• Journal of Biomedical Engineering Research
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• v.25 no.4
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• pp.295-300
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• 2004

Coil embolization technique has been used recently to treat cerebral aneurysms. When a giant or a multilobular aneurysm are treated by roils, filling an aneurysm sac completely with coils is difficult and partial blocking of an aneurysm sac is inevitable. Blood flow characteristics, which nay affect the embolization process of an aneurysm sac, are changed by the locations of coils for the Partially blocked aneurysms. Blood flow fields are also influenced by the geometry of a parent vessel. In order to suggest the coil locations effective for aneurysm embolization, the blood flow fields of lateral aneurysm models were analyzed for the different coil locations and parent vessel geometries. Three dimensional pulsatile flow fields are analyzed by numerical methods considering non-Newtonian viscosity characteristics of blood. Flow rate into the aneurysm sac (inflow rate) and wall shear stress, which are suspected as flow dynamic factors influencing aneurysm embolization, are also calculated. Inflow rates were smaller and the low wall shear stress zones were larger in the neck blocked models compared to the dome blocked models. Smaller inflow and larger low wall shear stress zones in the distal neck blocked model imply that the distal neck should be the effective coil locations for aneurysm embolization.

• Journal of Environmental Science International
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• v.18 no.6
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• pp.609-619
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• 2009

SWAT-K model is a modified version of the original SWAT, and is known to more accurately estimate the streamflows and pollutant loadings in Korean watersheds. In this study, its hydrological components were compared with those of HSPF in order to analyse the differences in total runoff including evapotranspiration(ET), surface flow, lateral flow and groundwater flow from the Chungju Dam watershed during $2000{\sim}2006$. Averaged annual runoff with SWAT-K overestimated by 1%, and HSPF underestimated it by 3% than observed runoff. Determination coefficients($R^2$) for observed and simulated daily streamflows by both the models were relatively good(0.80 by SWAT-K and 0.82 by HSPF). Potential ET and actual ET by HSPF were lower in winter, but similar or higher than those by SWAT-K. And though there were some differences in lateral and groundwater flows by two models because of the differences in hydrological algorithms, the results were to be reasonable. From the results, it was suggested that we should utilize a proper model considering the characteristic of study area and purposes of the model application because the simulated results from same input data could be different with models used. Also we should develop a novel model appropriate to Korean watersheds by enhancing limitations of the existing models in the future.

• Journal of Environmental Science International
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• v.22 no.5
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• pp.571-580
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• 2013

In this study, compared with the result of water surface elevation and water velocity on the establishment of river maintenance basic plan and result of HEC-GeoRAS based GIS, and after use the result of water surface elevation and velocity were observed in the Han stream on Jeju island, analysis 2 dimensional stream flow. the lateral hydraulic characteristics and curved channel of the stream were analyzed by applying SMS-RMA2 a 2 dimensional model. The results of the analysis using HEC-RAS model and HEC-GeoRAS model indicated that the distribution ranges of water surface elevation and water velocity were similar, but the water surface elevation by section showed a difference of 0.7~2.18 EL.m and 0.63~1.16 EL.m respectively, and water velocity also showed differences of maximum 1.58m/sec and 2.67m/sec. SMS-RMA2 analysis was done with the sphere of Muifa the typhoon as a boundary condition, and as a result, water velocity distribution was found to be 1.19 through 3.91 m/sec, and the difference of lateral water velocity in No. 97 through 99 the curved channel of the stream was analyzed to be 1.59 through 2.36 m/sec. In conclusion it is anticipated that the flow analysis of 2 dimension model of stream can reflect the hydraulic characteristics of the stream curved channel or width and shape, and can be applied effectively in the establishment of river maintenance basic plan or management and designing of stream.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.11a
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• pp.99-113
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• 1996

Taurine, a ${\beta}$-amino acid, plays an important role as a neuromodulator and is necessary for the normal development of the brain. Since de novo synthesis of taurine in the brain is minimal and in vivo studies suggest that taurine does not cross the blood-brain barrier, the blood-cerebrospinal fluid (CSF) barrier is likely to play a role in taurine transport between the central nervous system and the systemic circulation. Therefore, we examined in vivo elimination of taurine from the CSF in the rat to characterize in vivo kinetics of elimination for taurine from the CSF is consistent with the in vitro study. Using a stereotaxic device, cannulaes were placed into the lateral ventricle and the cisterna magna of the rat. Radio-labelled taurine and inulin (a marker of CSF flow) were injected into the lateral ventricle, and the concentrations of the labelled compounds in the CSF were monitored for up to 3 hrs in the cisterna magna. The apparent clearance of taurine from CSF was greater than the estimated CSF flow (p<0.005), indicating that there is a clearance process in addition to the CSF flow. Taurine distribution into the choroid plexus was at least 10 fold higher than that found in other brain areas (e.g., cerebellum, olfactory bulb and cortex). When unlabelled taurine was co-administered with radio-labelled taurine, the apparent clearance of the labeled taurine was reduced (p<0.01), suggesting a saturable disposition of taurine from CSF. Distribution of taurine into the choroid plexus, cerebellum, olfactory bulb and cortex was similarly diminished, indicating that the saturable uptake of taurine into these tissues is responsible for the non-linear disposition. A pharmacokinetic model involving first order elimination and saturable distribution described these data adequately. The Michaelis-Menten rate constant estimated from in vivo elimination study is similar to that obtained in the in vitro uptake experiment Collectively, our results demonstrate that taurine is transported in the choroid plexus via a taurine is cleared from the CSF via a saturable process. This process may be functionally relevant to taurine homeostasis in the brain.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.11
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• pp.1168-1179
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• 2006

The validity of an unsteady two-dimensional(2-D) numerical hydrodynamic and pollutant dispersion model(2DNHPDM) was evaluated using the data obtained from I-sa streams in Sooncheon, Chonnam, during rain-fall run-off. Field observations was conducted for 35 hours during the 10 hours rainfall event on 7th May 2005. The water level, 2-D velocity, flow field, and COD at seven points selected along the river were measured at intervals of one hour. The model was applied to describe two-dimensional movement of dissolved pollutants in meandering non-uniform river. Major physical processes affecting the lateral and horizontal mixing of the river flow were simulated. The model was proved effective in describing the hydrodynamics and dispersion of the river pollutants from its major tributaries as well as non-point sources.

• Korean Journal of Materials Research
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• v.9 no.3
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• pp.257-262
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• 1999

The selective area growth of GaN by metal organic chemical vapor deposition has been carried out on GaN/ sapphire substrate using $SiO_2$ mask. We investgated the effect of growth parameters such as flow rate of $NH_3$(500­~1300sccm) and the growth temperature(TEX>$950~1060^{\circ}C$) on the growth selectivity and characteristics of GaN using the Scanning Electron Microscopy(SEM). The selectivity of GaN improved as flow rate of NH, and growth temperature in­creased. But the grown GaN shapes on the substrate windows was independent of the flow rate of $NH_3$. On the pattern shapes such as circle, stripe, and radiational pattern(rotate the stripe pattern by $30^{\circ}, 45^{\circ}$), we observed the hexagonal pyramid, the lateral over growth on the mask layer, and the difference of the lateral growth rate depending on growth condition.

• Journal of Navigation and Port Research
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• v.27 no.3
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• pp.253-258
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• 2003

To evaluate the unsteady motion in laterally berthing maneuver, it is necessary to grasp very clearly the magnitude and properties of the hydrodynamic forces acting on ship hull in shallow water. In this study, numerical calculation was made to investigate quantitatively the hydrodynamic force according to the water depth for Wigley model using the CFD (Computational Fluid Dynamics) technique. Comparing the computational results to the experimental ones, the validity of the CFD method was verified. The numerical solutions evaluated the hydrodynamic force with good accuracy, and then captured the features of the flow field around the ship in detail. The transitional lateral force in a state ranging from rest to uniform motion is modeled by using the concept of the circulation.

• Proceedings of the Korean Geotechical Society Conference
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• 1999.03a
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• pp.481-488
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• 1999

This study, investigates the existing theoretical backgrounds in order to examine the behavior of lateral flow owing to the plasticity of soils when unsymmetrical surcharge is worked on polluted soils by the increase of water content compares and analyzes the results measured through model tests. Unsymmetrical surcharge is increased at regular intervals to soil tank made up the polluted soils and then the amounts of settlement, lateral displacement and upheaval are observed. Critical surcharge was decided ｑ$\sub$cr/= 3.42 C$\sub$u/ similar to those had proposed Terzaghi and JHI, and the value of ultimate capacity was decided ｑ$\sub$ult/= 7.71 C$\sub$u/ similar to that of Tschebotarioff and JHI.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.308-311
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• 2005

In this paper, we studied about the effects of the rotating cantilever pipe conveying fluid with a moving mass. The influences of a rotating angular velocity, the velocity of fluid flow and moving mass on the dynamic behavior of a cantilever pipe have been studied by the numerical method. The equation of motion is derived by using the Lagrange's equation. The cantilever pipe is modeled by the Euler-Bemoulli hew theory. When the velocity of a moving mass is constant, the lateral tip-displacement of a cantilever pipe is proportional to the moving mass and the angular velocity. In the steady state, the lateral tip-displacement of a cantilever pipe is more sensitive to the velocity of fluid than the angular velocity, and the axial deflection of a cantilever, pipe is more sensitive to the effect of a angular velocity.

• Macromolecular Research
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• v.12 no.2
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• pp.189-194
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• 2004

When water is evaporated quickly from a water-based colloidal suspension, colloidal particles protrude from the water surface, distorting it and generating lateral capillary forces between the colloidal particles. The protruded colloidal particles are then assembled into ordered colloidal crystalline domains that float on the water surface on account of their having a lower effective density than water. These colloidal crystal domains then assemble together by lateral capillary force and convective flow; the generated colloidal crystal has grain boundaries. The single domain size of the colloidal crystal could be controlled, to some extent, by changing the rate of water evaporation, but it seems very difficult to fabricate a single crystal over a large area of the water's surface without reorienting each colloidal crystal domain. To reorient such colloidal crystal domains, a glass plate was dipped into the colloidal suspension at a tilted angle because the meniscus (airwaterglass plate interface) is pinned and thinned by further water evaporation. The thinning meniscus generated a shear force and reoriented the colloidal crystalline domains into a single domain.