• Asian-Australasian Journal of Animal Sciences
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• v.33 no.2
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• pp.187-196
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• 2020

Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (F_ST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r² = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r² = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9949-9953
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• 2014

Objective: To evaluate the long term results among patients with soft tissue sarcoma of the thoracic wall. Materials and Methods: Twenty-six patients who were treated with pre-or postoperative radiotherapy between December 1980-December 2007, with a diagnosis of soft tissue sarcoma of the thoracic wall were retrospectively evaluated. Results: The median age was 44 years (14-85 years) and 15 of them were male. A total of 50% of patients were grade 3. The most common histologic type of tumor was undifferentiated pleomorphic sarcoma (26.9%). Tumor size varied between 2-25 cm (median 6.5 cm). Seventeen of the cases had marginal and 9 had wide local resection. Four cases received preoperative radiotherapy and 22 postoperative radiotherapy. Six of the patients with large and high grade tumors received chemotherapy. Median follow-up time was 82 months (9-309 months). Local recurrence and metastasis was detected in 34.6% and 42.3% of patients, respectively. Five-year local control (LC), disease-free survival (DFS), overall survival (OS), and disease-specific survival (DSS) were 62%, 38%, 69%, and 76% respectively. On univariate analysis, the patients with positive surgical margins had a markedly lower 5-year LC rate than patients with negative surgical margin, but the difference was not significant (43% vs 78%, p=0.1). Five-year DFS (66% vs 17%) and DSS (92% vs 60%) rates were significantly worse for the patients who had high grade tumors (p=0.01, p=0.008 respectively). Conclusions: Tumor grade and surgical margin are essential parameters for determining the prognosis of thoracic wall soft tissue sarcoma both in our series and the literature.

• The Journal of the Acoustical Society of Korea
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• v.24 no.2
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• pp.103-110
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• 2005

Providing adequate amount of spatial impression for spaciousness) has been known to be one of the most important design considerations for the good acoustics of rooms for music. and the measurement, of room acoustics using parameters. such as LEF and IACC, forms an essential part of such evaluation. However. it is unavoidable to use different transducers (figure of eight microphones. head and torso) for the measurement of each parameter and it tends to make the measurement procedure complicated. The Present work tried to provide a simpler way to measure these binaural room acoustic parameters including monaural ones with a single measurement system using both spatial information collected through a 5-channel microphone and a trained neural network. A computer simulation program, CATT-Acoustic V7.2. which allowed us to obtain exactly the same spatial information as a 5-channel microphone was used. since it requires quite a large amount of data for practical training of a neural network. Since each reflection has different energy. delay and direction, energy should be integrated properly. the concept of ray tracing method was applied inversely in this work. Also applying weightings according to the delay times was considered in this work. Finally, predicted results were compared with the measured data md their correlations were analyzed and discussed.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.15 no.4
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• pp.333-341
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• 2017

The Korea Atomic Energy Research Institute (KAERI) constructed the PyRoprocessing Integrated inactive Demonstration facility (PRIDE) to carry out experiments on engineering scale pyroprocessing. PRIDE has a large processing cell that human workers are not allowed to access, and thus the equipment inside is operated from outside using remote handling systems. It is therefore essential to examine the operability and maintainability of the equipment in view of remote handling systems, and the equipment is thoroughly examined in a mockup cell before it is installed in the processing cell. If the equipment is tested in a virtual mockup rather than in a mockup cell, the development cost can be significantly reduced. The PRIDE 3D simulator was integrated for virtual verification of equipment that will be installed in the processing cell. All remote handling devices in the actual PRIDE were also virtually installed in the PRIDE 3D simulator. The 3D model of the equipment was loaded and located in the exact position in the virtual processing cell. A scenario to replace an actual electrode was implemented in the PRIDE 3D simulator. The design of the equipment and the working procedures in the scenario were successfully evaluated. The results demonstrated that the PRIDE 3D simulator can be used successfully as an alternative to actual mockup testing.

• Asian Journal of Atmospheric Environment
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• v.9 no.4
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• pp.280-287
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• 2015

The high time-resolution monitoring data are essential to estimate rapid changes in chemical compositions, concentrations, formation mechanisms, and likely sources of atmospheric particulate matter (PM). In this study, $PM_{2.5}$ sulfate, $PM_{2.5}$, $PM_{10}$, and the number concentration of size-resolved PMs were monitored in Fukuoka, Japan by good time-resolved methods during the springtime. The highest monthly average $PM_{2.5}$ sulfate was found in May ($8.85{\mu}g\;m^{-3}$), followed by April ($8.36{\mu}g\;m^{-3}$), March ($8.13{\mu}g\;m^{-3}$), and June ($7.22{\mu}g\;m^{-3}$). The cases exceed the Japanese central government's safety standard for $PM_{2.5}$ ($35{\mu}g\;m^{-3}$) reached 10.11% during four months campaign. The fraction of $PM_{2.5}$ sulfate to $PM_{2.5}$ varied from 12.05% to 68.11% with average value of 35.49% throughout the entire period of monitoring. This high proportion of sulfate in $PM_{2.5}$ is an obvious characteristic of the ambient $PM_{2.5}$ in Fukuoka during the springtime. However, the average fraction of $PM_{2.5}$ sulfate to $PM_{2.5}$ in three rain events occurred during our intensive campaign fell right down to 15.53%. Unusually high $PM_{2.5}$ sulfate (> $30{\mu}g\;m^{-3}$) marked on three days were probably affected by the air parcels coming from the Chinese continent, the natural sulfur in the remote marine atmosphere, and a large number of ships sailing on the nearby sea. The theoretical number concentration of $(NH_4)_2SO_4$ in $PM_{0.5-0.3}$ was originally calculated and then compared to $PM_{2.5}$ sulfate. A close resemblance between the diurnal variations of the theoretically calculated number concentration of $(NH_4)_2SO_4$ in $PM_{0.5-0.3}$ and $PM_{2.5}$ sulfate concentration indicates that the secondary formed $(NH_4)_2SO_4$ was the primary form of sulfate in $PM_{2.5}$ during our monitoring period.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.12
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• pp.6550-6557
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• 2013

The public road construction projects awarded by the regional construction and management office, which is an affiliate of the Ministry of Land, Infrastructure and Transport, are managed by construction supervision officers. These officials frequently visit a large number of construction sites to conduct inspections and supervision tasks. Therefore, the site management efficiency is essential in terms of the time and money spent in travelling to the sites. The introduction of a site monitoring management system is considered necessary to minimize the number of site visits and enable remote monitoring of the construction progress to enhance the business efficiency of the construction supervision officers. In this study, a remote site monitoring system was constructed using web cameras for public road construction works. The trial applications were implemented by selecting ten constructions sites. The effectiveness of the system was analyzed to assess its applicability. In an assessment of the applicability of the verification results, remote site monitoring showed cost savings of approximately 35% compared to the existing site management. The guidelines for applying the site monitoring management system were provided, the introduction plan was investigated, and the improvement method was presented. The results showed that the system is likely to minimize the unnecessary site visits, remove the risk factors at vulnerable areas in the sites beforehand, and prevent a range of disasters and accidents. In addition, the quality of the infrastructures is likely to improve through the prevention of accidents and the elimination of substandard and faulty construction work.

• Journal of Nutrition and Health
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• v.6 no.4
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• pp.15-22
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• 1973

Sodium chloride plays an important role as the main condiment at daily meal. It is well known that humans require sodium chloride as an essential nutrient to keep the homeostasis of electrolytes. The amounts of salt intake may be a reflection of geography, culture and food habit rather than necessity. Lee has reported (1962) that Koreans ingest high amounts of sodium chloride in their meals, with an intake of excess carbohydrate (80-90% of total Calories) and low protein in their diet. This includes large amounts of rice, Kimchi and other fermented soybean products common in the Korean diet. This investigation was designed to study the dietary relations of sodium chloride to other nutrients in the Korean diet. Twenty four albino male rats, weighing from 290-300g, were divided into four dietary groups according to the amounts of carbohydrate, protein and fat in the basal diet. Each diet contained a rice powder as a carbohydrate source. Diet I was a control diet, Diet II, low protein, Diet III, low protein and low fat diet and Diet IV, low fat diet. All rats were provided with 3% sodium chloride solution. Diet and salt solution were given ad libitum. The experiment was carried out for 9 weeks during which time the body weight, the food intake, and 3% sodium chloride solution consumption were determined. At the 9th week, the urine was collected the blood sample from the artery of each rat for the analysis of sodium and potassium and other chemical studies. The rats were sacrificed and the kidney, adrenal, liver and spleen were measured, and observed changes of the pathological tissue in the kidney and adrenal. The results were summarized as follows: 1) The growth rate was higher in Diet I than in the other experimental diets (II, III and IV) after 4 weeks. There was no significant difference found between the experimental Diets II, III and IV. 2) The daily food intake was greater in the experimental diets II, III and IV than in the control diet. However, there was no difference among the high carbohydrate diets Diet II, III and IV. 3) The daily water (3% sodium chloride solution) intake was also greater in the Diets II, III and IV, than in the control diet. However, there was no difference between Diets II, III and IV. 4) The concentration of sodium and potassium in the blood were within the normal range in all diets. 5) The amount of sodium chloride in the urine was significantly greater in Diets II, III and IV than in the control diet. Diets II, III, IV had a larger amount of sodium solution consumption. 6) Observation of pathological tissue in the experimental diets found a cell proliferation in the glomerlulus of the kidney, while such change was not found in the control diet.

• Journal of KIISE:Information Networking
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• v.29 no.5
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• pp.583-594
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• 2002

Assuring the security of group communications such as tole-conference and software distribution requires a common group key be shared among the legal members in a secure manner. Especially for large groups with frequent membership change, efficient rekey mechanism is essential for scalability. One of the most popular ways to provide sealable rekey is to partition the group into several subgroups. In this paper, we propose a two-layered key management scheme which combines DEP and CBT, a protocol in which subgroup manager cannot access the multicast data and another that has a multi-core, respectively. We also select sub-group key management protocols suitable for our structure and design new rekey protocols to exclude the subgroup managers from the multicast data. Compared to previous protocols based on CBT, our scheme provides forward secrecy, backward secrecy and scalability. This would reduce the number of encryption and decryption for a rekey message and would improve the efficiency number of rekey messages and the amount of information related to group members that group managers must maintain compared to DEP.

• Journal of KIISE:Computer Systems and Theory
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• v.29 no.5
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• pp.245-256
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• 2002

Shadows are important elements in producing a realistic image. Generation of exact shapes and positions of shadows is essential in rendering since it provides users with visual cues on the scene. It is also very important to be able to create soft shadows resulted from area light sources since they increase the visual realism drastically. In spite of their importance. the existing shadow generation algorithms still have some problems in producing realistic shadows in real-time. While image-based rendering techniques can often be effective1y applied to real-time shadow generation, such techniques usually demand so large memory space for storing preprocessed shadow maps. An effective compression method can help in reducing memory requirement, only at the additional decoding costs. In this paper, we propose a new image-barred shadow generation method based on image warping. With this method, it is possible to generate realistic shadows using only small sizes of pre-generated shadow maps, and is easy to extend to soft shadow generation. Our method will be efficiently used for generating realistic scenes in many real-time applications such as 3D games and virtual reality systems.

• Cartoon and Animation Studies
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• s.31
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• pp.209-226
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• 2013

With rapidly changing multimedia environment, various artistic changes and digitalized up-to-date social infra, urban environment construction based on culture contents has been activated. The large image in front of urban building that is expressed as media-façade, increasing rapidly in a recent period, is not a new thing at all. In addition, IT technology molten in city space is testing the possibility of new media through the meeting with architecture. However, unlike its infra enlargement, the definition about media-façade is not clear so the system was constructed in a level of night lightscape or outdoor image advertisement. The purpose of this guideline is the regulation from the negative aspect rather than the possibility of various visual, artistic media expressions. Therefore, it could not show essential concept of media-façade. Moreover, most of companies or building owners focus on short-term profit and marketing effect rather than prepare various contents so they can not use constructed infra properly. After all, in many cases, they discolor the meaning of media-façade. This paper is a pilot study to grasp the current definition of media-façade to construct right guideline of media-façade. On the basis of this study, it will prepare academic definition of media-façade and construct the guideline for design evaluation.