• Title/Summary/Keyword: laboratory method

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HV-SoP Technology for Maskless Fine-Pitch Bumping Process

  • Son, Jihye;Eom, Yong-Sung;Choi, Kwang-Seong;Lee, Haksun;Bae, Hyun-Cheol;Lee, Jin-Ho
    • ETRI Journal
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    • v.37 no.3
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    • pp.523-532
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    • 2015
  • Recently, we have witnessed the gradual miniaturization of electronic devices. In miniaturized devices, flip-chip bonding has become a necessity over other bonding methods. For the electrical connections in miniaturized devices, fine-pitch solder bumping has been widely studied. In this study, high-volume solder-on-pad (HV-SoP) technology was developed using a novel maskless printing method. For the new SoP process, we used a special material called a solder bump maker (SBM). Using an SBM, which consists of resin and solder powder, uniform bumps can easily be made without a mask. To optimize the height of solder bumps, various conditions such as the mask design, oxygen concentration, and processing method are controlled. In this study, a double printing method, which is a modification of a general single printing method, is suggested. The average, maximum, and minimum obtained heights of solder bumps are $28.3{\mu}m$, $31.7{\mu}m$, and $26.3{\mu}m$, respectively. It is expected that the HV-SoP process will reduce the costs for solder bumping and will be used for electrical interconnections in fine-pitch flip-chip bonding.

Evaluation of the Method for Total Homocysteine in Plasma Using LC-MS/MS (LC-MS/MS를 이용한 Homocysteine 측정과 그 유용성 평가)

  • Jun, Sun-Hee;Lim, Mi-Suk;Jung, Yong-Sun;Song, Jung-Han
    • Korean Journal of Clinical Laboratory Science
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    • v.37 no.1
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    • pp.22-26
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    • 2005
  • Total homocysteine is now considered a risk factor for cardiovascular diseases. I increased interest has led to a multitude of studies requiring the determination of total homocysteine in conjunction with other factor. There are various methods for measuring total homocysteine, including HPLC, FPIA, GC-MS and LC-MS/MS. The most recent method for measuring total homocysteine uses a deuterium-labelled internal standard and tandem mass spectrometry. This development requires no derivatization and therefore leads to an increase in sample throughput compared to other techniques. We have evaluated the method for homocysteine by the LC-MS/MS method, and the correlation between the FPIA method and the LC-MS/MS method. The standard curve (0, 5, 10, 20, 50, 100 uM) was linear over the range examined (up to 100 uM). The lower limit of quantification (CV < 10 %) was 0.5 uM/L and the lower limit of detection (S/N >3) was 0.1 uM/L. Intra-assay variation and inter-assay variation were both <6 %. The comparision study for homocysteine concentration showed good correlation (r=0.9684) between the FPIA method and LC-MS/MS methods. Our conclusion is that the method showed relatively good precision, and was rapid and accurate.

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Effective Multiplexing Method for Conditional Access System in Terrestrial DMB

  • Lee, Yong-Hoon;Lee, Gwang-Soon;Lee, Jin-Hwan;Ahn, Chung-Hyun;Lee, Soo-In;Kim, Nam
    • ETRI Journal
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    • v.30 no.6
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    • pp.859-861
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    • 2008
  • This letter proposes a conditional access system (CAS) suitable for use in terrestrial digital multimedia broadcasting (T-DMB), based on an effective multiplexing method to provide encrypted T-DMB services. Specifically, the proposed multiplexing method for a CAS is designed to reduce the additional bit rate while assuring easy access to the designated encrypted services. Finally, the performance of the implemented CAS is confirmed through implementation and a broadcasting experiment under various service environments.

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Technology Selection Method for Optimal Energy Storage (기술 특성치 스크리닝을 통한 최적 에너지저장 기술 선정 방법)

  • Seong Jegarl;Ji Hyun Lee;Hyunshil Kim;Jeseok Shin;Jihun Lim
    • New & Renewable Energy
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    • v.19 no.1
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    • pp.31-40
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    • 2023
  • The expanding significance of energy storage (ES) technology is increasing the acceptability of power systems by augmenting renewable energy supply. To deploy such ES technologies, we must select the optimal technology that meets the requirements of the system and confirm the technical and economic feasibility of the business model based on it. Herein, we propose a method and tool for selecting the optimal ES technology suitable for meeting the requirements of the system, based on its performance characteristics. The method described in this study can be used to discover and apply various ES technologies and develop business models with excellent economic feasibility.

Accurate Detection of a Defective Area by Adopting a Divide and Conquer Strategy in Infrared Thermal Imaging Measurement

  • Jiangfei, Wang;Lihua, Yuan;Zhengguang, Zhu;Mingyuan, Yuan
    • Journal of the Korean Physical Society
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    • v.73 no.11
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    • pp.1644-1649
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    • 2018
  • Aiming at infrared thermal images with different buried depth defects, we study a variety of image segmentation algorithms based on the threshold to develop global search ability and the ability to find the defect area accurately. Firstly, the iterative thresholding method, the maximum entropy method, the minimum error method, the Ostu method and the minimum skewness method are applied to image segmentation of the same infrared thermal image. The study shows that the maximum entropy method and the minimum error method have strong global search capability and can simultaneously extract defects at different depths. However none of these five methods can accurately calculate the defect area at different depths. In order to solve this problem, we put forward a strategy of "divide and conquer". The infrared thermal image is divided into several local thermal maps, with each map containing only one defect, and the defect area is calculated after local image processing of the different buried defects one by one. The results show that, under the "divide and conquer" strategy, the iterative threshold method and the Ostu method have the advantage of high precision and can accurately extract the area of different defects at different depths, with an error of less than 5%.

Preparation of Well-Dispersed Nanosilver in MIL-101(Cr) Using Double-Solvent Radiation Method for Catalysis

  • Chang, Shuquan;Liu, Chengcheng;Fu, Heliang;Li, Zheng;Wu, Xian;Feng, Jundong;Zhang, Haiqian
    • Nano
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    • v.13 no.12
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    • pp.1850145.1-1850145.8
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    • 2018
  • In this study, a double-solvent radiation method is proposed to prepare silver nanoparticles in the pores of metal-organic framework MIL-101(Cr). The results reveal that well-dispersed silver nanoparticles with a diameter of about 2 nm were successfully fabricated in the cages of monodisperse octahedral MIL-101(Cr) with a particle size of about 400 nm. The structure of MIL-101(Cr) was not destroyed during the chemical treatment and irradiation. The resulting Ag/MIL-101 exhibits excellent catalytic performance for the reduction of 4-nitrophenol. This method can be extended to prepare other single or bimetallic components inside porous materials.

Establishment of a Tm-shift Method for Detection of Cat-Derived Hookworms

  • Fu, Yeqi;Liu, Yunqiu;Abuzeid, Asmaa M.I.;Huang, Yue;Zhou, Xue;He, Long;Zhao, Qi;Li, Xiu;Liu, Jumei;Ran, Rongkun;Li, Guoqing
    • Parasites, Hosts and Diseases
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    • v.57 no.1
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    • pp.9-15
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    • 2019
  • Melting temperature shift ($T_m-shift$) is a new detection method that analyze the melting curve on real-time PCR thermocycler using SYBR Green I fluorescent dye. To establish a $T_m-shift$ method for the detection of Ancylostoma ceylanicum and A. tubaeforme in cats, specific primers, with GC tail of unequal length attached to their 5' end, were designed based on 2 SNP loci (ITS101 and ITS296) of the internal transcribed spacer 1 (ITS1) sequences. The standard curve of $T_m-shift$ was established using the standard plasmids of A. ceylanicum (AceP) and A. tubaeforme (AtuP). The $T_m-shift$ method stability, sensitivity, and accuracy were tested with reference to the standard curve, and clinical fecal samples were also examined. The results demonstrated that the 2 sets of primers based on the 2 SNPs could accurately distinguish between A. ceylanicum and A. tubaeforme. The coefficient of variation (CV) of $T_m$- values of AceP and AtuP was 0.07% and 0.06% in ITS101 and was 0.06% and 0.08% in ITS296, respectively. The minimum detectable DNA concentration was $5.22{\times}10^{-6}$ and $5.28{\times}10^{-6}ng/{\mu}l$ samples of AceP and AtuP, respectively. The accuracy of $T_m-shift$ method reached 100% based on examination of 10 hookworm DNA samples with known species. In the clinical detection of hookworm in 69 stray cat fecal sample, the $T_m-shift$ detection results were consistent with the microscopic examination and successfully differentiated between the 2-hookworm species. In conclusion, the developed method is a rapid, sensitive and accurate technique and can provide a promising tool for clinical detection and epidemiological investigation of cat-derived hookworms.

Emission Profile Studies of Thermionic Cathodes and Field Emitters

  • Tawa, Yasuhiro;Kai, Junjiro;Tama, Masayoshi;Ijima, Kenji;Saito, Tsunenari
    • 한국정보디스플레이학회:학술대회논문집
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    • 2002.08a
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    • pp.371-375
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    • 2002
  • Emissions of thermionic cathodes and field emitters were studied using a cathode emission profiler which works based on the anode scanning method. Findings about impregnated cathodes in thermal activation and gas poisoning processes are shown. Effects of surface treatments for field emitters are studied from the viewpoint of emission profiles and characteristics of the emitters.

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