• Title/Summary/Keyword: laboratory diagnosis

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Prevalence of Malaria in Pregnant Women in Lagos, South-West Nigeria

  • Agomo, Chimere O.;Oyibo, Wellington A.;Anorlu, Rose I.;Agomo, Philip U.
    • Parasites, Hosts and Diseases
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    • v.47 no.2
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    • pp.179-183
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    • 2009
  • Prevalence rates reported for malaria in pregnancy in Nigeria vary considerably. The accuracy of results of malaria diagnosis is dependent on training, experience, and motivation of the microscopist as well as the laboratory facility available. Results of training programmes on malaria microscopy have shown low levels of sensitivity and specificity of those involved in malaria diagnosis routinely and for research. This study was done to ascertain the true prevalence of malaria in pregnancy in Lagos, South-West Nigeria. A total of 1,084 pregnant women were recruited into this study. Blood smears stained with Giemsa were used for malaria diagnosis by light microscopy. Malaria infection during pregnancy presents mostly as asymptomatic infection. The prevalence of malaria in this population was 7.7% (95% confidence interval; 6.2-9.4%). Factors identified to increase the risk of malaria infection include young maternal age (<20 years), and gravidity (primigravida). In conclusion, this study exposes the over-diagnosis of malaria in pregnancy and the need for training and retraining of laboratory staffs as well as establishing the malaria diagnosis quality assurance programme to ensure the accuracy of malaria microscopy results at all levels.

A Study on the System and Operation of Laboratory Safety Inspection and Diagnosis (연구실 안전점검 및 정밀안전진단제도 개선에 관한 연구)

  • Woo, In-Sung;Hwang, Myung-Hwan;Lee, Hong-Ju
    • Journal of the Korean Institute of Gas
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    • v.23 no.2
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    • pp.45-54
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    • 2019
  • According to the Laboratory Safety Act, each laboratory in the field of science and technology must conduct safety inspections and diagnosis every year or every two years. At present, the relevant guidelines are not clear, so there is a high possibility that inspection and diagnosis will become ineffective. In the laboratory, there is a pre-risk factor analysis system for hazardous factors, but there are many difficulties in implementation due to lack of education and understanding of the researchers, excessive work, etc. For the analysis of the opinions of experts in the safety field using the Delphi technique, we analyzed the following items: 1. Consideration in applying the Lab Safety Act, 2. Consideration in Lab Safety inspection and diagnosis, and 3. Government policy necessary for Lab. safety. Through the investigation and analysis of the detailed items, we extracted for problems and alternatives in current laboratory safety diagnosis and current law.

Application of Diagnostic Laboratory Tests in the Field of Oral Medicine: A Narrative Review

  • Ji Woon, Park;Yeong-Gwan, Im
    • Journal of Korean Dental Science
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    • v.15 no.2
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    • pp.101-111
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    • 2022
  • The purpose of laboratory tests in the field of oral medicine can be divided into two categories: (1) medical evaluation of patients with systemic diseases that are planning to receive dental care and (2) diagnosis of patients with certain oral diseases. First, laboratory tests are commonly used to evaluate patients with systemic diseases who need dental management. A combination of multiple tests is usually prescribed as a test panel to diagnose and assess a specific disease. Test panels closely related to oral medicine include those for rheumatoid arthritis, connective tissue disease/lupus, liver function, thyroid screening, anemia, and bleeding disorders. Second, laboratory tests are used as auxiliary diagnostic methods for certain oral diseases. They often provide crucial diagnostic information for infectious diseases caused by bacteria, fungi, and viruses that are associated with pathology in the oral and maxillofacial regions. Laboratory tests for infectious diseases are composed of growth-dependent methods, immunologic assays, and molecular biology. As the field develops, further application of laboratory tests, including synovial fluid analysis in temporomandibular joint disorders, salivary diagnostics, and hematologic biomarkers associated with temporomandibular disorders and orofacial pain conditions, is currently under scrutiny for their reliability as diagnostic tools.

Metastatic intestinal adenocarcinoma with osseous metaplasia in two Domestic Korean Shorthair cats

  • Jae-Ha Jung;Na-Yon Kim;Yeseul Yang;Dansong Seo;Goeun Choi;Hyunki Hong;Taeseong Moon;Hyeong-Mok Kim;Jihee Han;Jihee Hong;Yongbaek Kim
    • Journal of Veterinary Science
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    • v.24 no.5
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    • pp.64.1-64.6
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    • 2023
  • Two Domestic Korean Shorthair cats presented with dyschezia and vomiting. Computed tomography revealed a colonic mass with calcification and lymph node metastasis in case 1, and a small intestinal mass with disseminated mesenteric metastasis and calcification in case 2. Histopathology revealed intestinal adenocarcinoma with osseous metaplasia. Case 1 died two months after surgery from distant metastasis; and case 2 showed no metastasis for five months but presented with anorexia, euthanized seven months after diagnosis. Metastatic intestinal adenocarcinoma with bone formation should be considered as differential diagnosis for calcification on imaging, and lymph node metastasis at diagnosis may indicate poor prognosis.

Development of Fuzzy Rule-based Liver Function Test Diagnosis System (퍼지 규칙기반 간 기능 검사 해석 시스템의 개발)

  • Kim, Jong-Won;Oh, Kyung-Whan
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.05
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    • pp.155-160
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    • 1992
  • Liver function test is one of the most common tests for diagnosis and follow-up of patients and for heal th screening. Automatic interpretation and suggestions on the diagnostic possibilities contribute to shorten the interpretation time of the test results and help to provide qualified health care. Fuzzy logic has been recently introduced and being spread for these purposes. The present study aims at model Ins the foray rule-based laboratory diagnosis system. The fuzzy rule-based laboratory diagnosis system was applied to the diagnosis regarding liver function test. The system was evaluated by comparing with the stepwise multivariate discriminant function analysis, which showed similar results, and the overall accuracy of the fuzzy diagnosis system was about 80%.

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Development of a High-performance COVID-19 Diagnostic Kit Employing Improved Antibody-quantum dot Conjugate

  • Seongsoo Kim;Hyunsoo Na;Hong-Geun Ahn;Han-Sam Park;Jaewoong Seol;Il-Hoon Cho
    • Biomedical Science Letters
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    • v.29 no.4
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    • pp.344-354
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    • 2023
  • This study emphasizes the importance of early diagnosis and response to COVID-19, leading to the development of a rapid diagnostic kit using quantum dots. The research focuses on finely tuning bioconjugation with quantum dots to enhance the accuracy and sensitivity of COVID-19 diagnosis. We have developed a COVID-19 rapid diagnostic kit that exhibits a sensitivity more than 50 times higher than existing COVID-19 diagnostic kits. Quantum dots enable the accurate detection of COVID-19 viral antigens even at low concentrations, providing a rapid response in the early stages of infection. The COVID-19 quantum dot diagnostic kit offers quick analysis time, utilizing the quantum properties of particles to swiftly measure COVID-19 infection for immediate response and isolation measures. Additionally, this diagnostic kit allows for multiple analyses with ease, as multiple quantum dots can detect various antigens and antibodies simultaneously in a single experiment. This efficiency enhances testing, reduces sample requirements, and lowers experimental costs. The application of this diagnostic technology is anticipated in the future for early diagnosis and monitoring of other infectious diseases.

The Monitoring System with PV Module-level Fault Diagnosis Algorithm (태양전지모듈 고장 진단 알고리즘을 적용한 모니터링시스템)

  • Ko, Suk-Whan;So, Jung-Hun;Hwang, Hye-Mi;Ju, Young-Chul;Song, Hyung-June;Shin, Woo-Gyun;Kang, Gi-Hwan;Choi, Jung-Rae;Kang, In-Chul
    • Journal of the Korean Solar Energy Society
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    • v.38 no.3
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    • pp.21-28
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    • 2018
  • The objects of PV (Photovoltaic) monitoring system is to reduce the loss of system and operation and maintenance costs. In case of PV plants with configured of centralized inverter type, only 1 PV module might be caused a large loss in the PV plant. For this reason, the monitoring technology of PV module-level that find out the location of the fault module and reduce the system losses is interested. In this paper, a fault diagnosis algorithm are proposed using thermal and electrical characteristics of PV modules under failure. In addition, the monitoring system applied with proposed algorithm was constructed. The wireless sensor using LoRa chip was designed to be able to connect with IoT device in the future. The characteristics of PV module by shading is not failure but it is treated as a temporary failure. In the monitoring system, it is possible to diagnose whether or not failure of bypass diode inside the junction box. The fault diagnosis algorithm are developed on considering a situation such as communication error of wireless sensor and empirical performance evaluation are currently conducting.

Studies on Diagnosis for Pullorum Disease Comparative Experiments for the Diagnosis of Pullorum Disease by Tube Agglutination and Agar-gel Precipitin Tests with Chicken Sera (닭의 추백리병에 관한 연구 I. 추백리 진단에 있어서 혈청응집과 Agar-gel 침강반응과의 비교 시험)

  • Choi, J.Y.;Lee, S.Y.;Lee, C.K.
    • Korean Journal of Veterinary Research
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    • v.10 no.2
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    • pp.1-5
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    • 1970
  • In these studies the efficracy of plate, tube agglutination and agar-gel precipitin test were compared for the detection of pullorum infected chickens. From all the chickens showing positive reaction in agar-gel precipitin test, Salmonella pullorum organisms were isolated.

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Tumor Markers for Diagnosis, Monitoring of Recurrence and Prognosis in Patients with Upper Gastrointestinal Tract Cancer

  • Jing, Jie-Xian;Wang, Yan;Xu, Xiao-Qin;Sun, Ting;Tian, Bao-Guo;Du, Li-Li;Zhao, Xian-Wen;Han, Cun-Zhi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10267-10272
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    • 2015
  • To evaluate the value of combined detection of serum CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS for the clinical diagnosis of upper gastrointestinal tract (GIT) cancer and to analyze the efficacy of these tumor markers (TMs) in evaluating curative effects and prognosis. A total of 573 patients with upper GIT cancer between January 2004 and December 2007 were enrolled in this study. Serum levels of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were examined preoperatively and every 3 months postoperatively by ELISA. The sensitivity of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were 26.8%, 36.2%, 42.9%, 2.84%, 25.4%, 34.6%, 34.2% and 30.9%, respectively. The combined detection of CEA+CA199+CA242+CA724 had higher sensitivity and specificity in gastric cancer (GC) and cardiac cancer, while CEA+CA199+CA242+SCC was the best combination of diagnosis for esophageal cancer (EC). Elevation of preoperative CEA, CA19-9 and CA24-2, SCC and CA72-4 was significantly associated with pathological types (p<0.05) and TNM staging (p<0.05). Correlation analysis showed that CA24-2 was significantly correlated with CA19-9 (r=0.810, p<0.001). The levels of CEA, CA19-9, CA24-2, CA72-4 and SCC decreased obviously 3 months after operations. When metastasis and recurrence occurred, the levels of TMs significantly increased. On multivariate analysis, high preoperative CA72-4, CA24-2 and SCC served as prognostic factors for cardiac carcinoma, GC and EC, respectively. combined detection of CEA+CA199+CA242+SCC proved to be the most economic and practical strategy in diagnosis of EC; CEA+CA199+CA242+CA724 proved to be a better evaluation indicator for cardiac cancer and GC. CEA and CA19-9, CA24-2, CA72-4 and SCC, examined postoperatively during follow-up, were useful to find early tumor recurrence and metastasis, and evaluate prognosis. AFP, TPA and TPS have no significant value in diagnosis of patients with upper GIT cancer.

Rotor Failures Diagnosis of Squirrel Cage Induction Motors with Different Supplying Sources

  • Menacer, Arezki;Champenois, Gerard;Nait Said, Mohamed Said;Benakcha, Abdelhamid;Moreau, Sandrine;Hassaine, Said
    • Journal of Electrical Engineering and Technology
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    • v.4 no.2
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    • pp.219-228
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    • 2009
  • The growing application and the numerous qualities of induction motors (1M) in industrial processes that require high security and reliability levels has led to the development of multiple methods for early fault detection. However, various faults can occur, such as stator short-circuits and rotor failures. Traditionally the diagnosis machine is done through a sinusoidal power supply, in the present paper we study experimentally the effects of the rotor failures, such as broken rotor bars in function of the ac supplying, the load and show the impact of the converter from diagnosis of the machine. The technique diagnosis used is based on the spectral analysis of stator currents or stator voltages respectively according to the types of induction motor ac supplying. So, four different ac supplying are considered: ${\odot}$ the IM is directly by the balanced three-phase network voltage source, ${\odot}$ the IM is fed by a sinusoidal current source given the controlled by hysteresis, ${\odot}$ the IM is fed (in open loop) by a scalar control imposing through ratio V/f=constant, ${\odot}$ the IM is controlled through a vector control using space vector pulse width modulation (SVPWM) technique inverter with an outer speed loop.