Journal of Veterinary Science

The Korean Society of Veterinary Science (대한수의학회)
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Metastatic intestinal adenocarcinoma with osseous metaplasia in two Domestic Korean Shorthair cats

  • Jae-Ha Jung (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Na-Yon Kim (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Yeseul Yang (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Dansong Seo (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Goeun Choi (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Hyunki Hong (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Taeseong Moon (Eum Animal Medical Center) ;
  • Hyeong-Mok Kim (Eum Animal Medical Center) ;
  • Jihee Han (Top Care Animal Medical Center) ;
  • Jihee Hong (Top Care Animal Medical Center) ;
  • Yongbaek Kim (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University)
  • Received : 2023.05.03
  • Accepted : 2023.07.11
  • Published : 2023.09.30
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Abstract

Two Domestic Korean Shorthair cats presented with dyschezia and vomiting. Computed tomography revealed a colonic mass with calcification and lymph node metastasis in case 1, and a small intestinal mass with disseminated mesenteric metastasis and calcification in case 2. Histopathology revealed intestinal adenocarcinoma with osseous metaplasia. Case 1 died two months after surgery from distant metastasis; and case 2 showed no metastasis for five months but presented with anorexia, euthanized seven months after diagnosis. Metastatic intestinal adenocarcinoma with bone formation should be considered as differential diagnosis for calcification on imaging, and lymph node metastasis at diagnosis may indicate poor prognosis.

Keywords

Acknowledgement

The authors thank EUM Animal Medical Center, Hwaseong, Top Care Animal Medical Center, Goyang, and PATH Inc., Seoul, South Korea for providing the patient information and technical assistance.

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