• Title/Summary/Keyword: laboratory analysis

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VIBRATION SIGNAL ANALYSIS OF MAIN COOLANT PUMP FLYWHEEL BASED ON HILBERT-HUANG TRANSFORM

  • LIU, MEIRU;XIA, HONG;SUN, LIN;LI, BIN;YANG, YANG
    • Nuclear Engineering and Technology
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    • v.47 no.2
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    • pp.219-225
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    • 2015
  • In this paper, a three-dimensional model for the dynamic analysis of a flywheel based on the finite element method is presented. The static structure analysis for the model provides stress and strain distribution cloud charts. The modal analysis provides the basis of dynamic analysis due to its ability to obtain the natural frequencies and the vibration-made vectors of the first 10 orders. The results show the main faults are attrition and cracks, while also indicating the locations and patterns of faults. The harmonic response simulation was performed to gain the vibration response of the flywheel under operation. In this paper, we present a Hilbert-Huang transform (HHT) algorithm for flywheel vibration analysis. The simulation indicated that the proposed flywheel vibration signal analysis method performs well, which means that the method can lay the foundation for the detection and diagnosis in a reactor main coolant pump.

Uncertainty Evaluation of the Analysis of Methamphetamine and Amphetamine in Human Hair by GC/MS (GC/MS를 이용한 모발 중 메스암페타민 및 암페타민 분석의 측정불확도 평가)

  • Kim, Jin-Young;Kim, Jong-Sang;Kim, Min-Kyoung;Lee, Jae-Il;Suh, Yong-Jun;In, Moon-kyo
    • YAKHAK HOEJI
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    • v.51 no.3
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    • pp.206-213
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    • 2007
  • Recently estimating the uncertainty of an analytical result has become an essential part of quantitative analysis. This study describes the uncertainty of the measurement for the determination of methamphetamine and its major metabolite amphetamine in human hair, The method consists of washing, drying, weighing, incubation and extraction with methanolic HCI solution, clean-up, trifluoroacetyl derivatization, and qualification/quantification of residues by gas chromatography/mass spectrometry (GC/MS). Traceability of measurement was established through traceable standards and calibrated volumetric equipment and measuring instruments. Measurement uncertainty associated with each analyte in real samples was estimated using quality control (QC) data. The main source of combined standard uncertainty comprised two components, which are uncertainties associated with calibration linearity and variations in QC, while those associated with preparation of analytical standards and sample weighing were not so important considering the degree of contribution. Relative combined standard uncertainties associated with the described method ranged for individual analytes from 4.99 to5.03%.

Genetic Variant in CLPTM1L Confers Reduced Risk of Lung Cancer: a Replication Study in Chinese and a Meta-analysis

  • Luo, Xia;Lamsal, Laxmi Pangeni;Xu, Wen-Juan;Lu, Jie;Lu, Yan-Jun;Shen, Ying;Guan, Qing
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9241-9247
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    • 2014
  • Background: Rs31489 in the cleft lip and palate transmembrane1-like gene (CLPTM1L) has been identified to be associated with lung cancer through genome-wide association studies (GWAS). However, some recent replication studies yielded inconclusive results. Thus, we undertook this study to investigate the precise effect of rs31489 on lung cancer susceptibility. Materials and Methods: A hospital-based case-control study in 1,673 Chinese subjects (611 individuals with lung cancer and 1,062 controls) and a meta-analysis among 32,199 subjects (16,364 cases and 15,835 controls) were performed in this study. Results: In our case-control study, rs31489 was inversely associated with lung cancer (AC versus CC: OR=0.68, 95%CI=0.52-0.88; additive model: OR=0.68, 95%CI=0.54-0.85; dominant model: OR=0.65, 95%CI =0.51-0.84). Stratification analysis by smoking status showed a significant association and strong genetic effect in non-smokers but not in smokers. Our meta-analysis further confirmed the association, although with significant heterogeneity contributed by study design and source of controls, as shown by stratified analysis. Sensitive and cumulative analyses both indicated robust stability of our results. In addition, there was no observable publication bias in our meta-analysis. Conclusions: Overall, the findings from our replication study and meta-analysis demonstrated that CLPTM1L gene rs31489 is significantly associated with lung cancer.

Partial Least Squares Based Gene Expression Analysis in EBV-Positive and EBV-Negative Posttransplant Lymphoproliferative Disorders

  • Wu, Sa;Zhang, Xin;Li, Zhi-Ming;Shi, Yan-Xia;Huang, Jia-Jia;Xia, Yi;Yang, Hang;Jiang, Wen-Qi
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6347-6350
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    • 2013
  • Post-transplant lymphoproliferative disorder (PTLD) is a common complication of therapeutic immunosuppression after organ transplantation. Gene expression profile facilitates the identification of biological difference between Epstein-Barr virus (EBV) positive and negative PTLDs. Previous studies mainly implemented variance/regression analysis without considering unaccounted array specific factors. The aim of this study is to investigate the gene expression difference between EBV positive and negative PTLDs through partial least squares (PLS) based analysis. With a microarray data set from the Gene Expression Omnibus database, we performed PLS based analysis. We acquired 1188 differentially expressed genes. Pathway and Gene Ontology enrichment analysis identified significantly over-representation of dysregulated genes in immune response and cancer related biological processes. Network analysis identified three hub genes with degrees higher than 15, including CREBBP, ATXN1, and PML. Proteins encoded by CREBBP and PML have been reported to be interact with EBV before. Our findings shed light on expression distinction of EBV positive and negative PTLDs with the hope to offer theoretical support for future therapeutic study.

Dynamic Characteristic Analysis of Rotating Type Axial Phase Permanent Magnet Transverse Flux Machine (축방향 2상 영구자석형 횡자속 회전기의 동특성 해석)

  • Lee, Ji-Young;Lee, In-Jae;Kang, Do-Hyun;Chang, Jung-Hwan;Kim, Ji-Won;Chung, Si-Uk
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1029-1030
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    • 2007
  • This paper describes the dynamic analysis method and the characteristics of rotating type transverse flux motors excited by permanent magnets; the machine is called TFRM in here. A prototype of TFRM, made by combing soft magnetic composite (SMC) core, is introduced first, then the magneto static and dynamic analysis methods are explained. Analysis results are compared with measured results, and finally the effects of the proposed dynamic analysis method and the characteristics of TFRM are discussed.

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Obliquely incident earthquake for soil-structure interaction in layered half space

  • Zhao, Mi;Gao, Zhidong;Wang, Litao;Du, Xiuli;Huang, Jingqi;Li, Yang
    • Earthquakes and Structures
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    • v.13 no.6
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    • pp.573-588
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    • 2017
  • The earthquake input is required when the soil-structure interaction (SSI) analysis is performed by the direct finite element method. In this paper, the earthquake is considered as the obliquely incident plane body wave arising from the truncated linearly elastic layered half space. An earthquake input method is developed for the time-domain three-dimensional SSI analysis. It consists of a new site response analysis method for free field and the viscous-spring artificial boundary condition for scattered field. The proposed earthquake input method can be implemented in the process of building finite element model of commercial software. It can result in the highly accurate solution by using a relatively small SSI model. The initial condition is considered for the nonlinear SSI analysis. The Daikai subway station is analyzed as an example. The effectiveness of the proposed earthquake input method is verified. The effect of the obliquely incident earthquake is studied.

Systematic Review and Meta-Analysis of Antibiotic-Impregnated Shunt Catheters on Anti-Infective Effect of Hydrocephalus Shunt

  • Zhou, Wen-xiu;Hou, Wen-bo;Zhou, Chao;Yin, Yu-xia;Lu, Shou-tao;Liu, Guang;Fang, Yi;Li, Jian-wen;Wang, Yan;Liu, Ai-hua;Zhang, Hai-jun
    • Journal of Korean Neurosurgical Society
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    • v.64 no.2
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    • pp.297-308
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    • 2021
  • Objective : Shunt infection is a common complication while treating hydrocephalus. The antibiotic-impregnated shunt catheter (AISC) was designed to reduce shunt infection rate. A meta-analysis was conducted to study the effectiveness of AISCs in reduction of shunt infection in terms of age, follow-up time and high-risk patient population. Methods : This study reviewed literature from three databases including PubMed, EMBASE, and Cochrane Library (from 2000 to March 2019). Clinical studies from controlled trials for shunt operation were included in this analysis. A subgroup analysis was performed based on the patient's age, follow-up time and high-risk population. The fixed effect in RevMan 5.3 software (Cochrane Collaboration) was used for this meta-analysis. Results : This study included 19 controlled clinical trials including 10105 operations. The analysis demonstrated that AISC could reduce the infection rate in shunt surgery compared to standard shunt catheter (non-AISC) from 8.13% to 4.09% (odds ratio [OR], 0.48; 95% confidence interval [CI], 0.40-0.58; p=0.01; I2=46%). Subgroup analysis of different age groups showed that AISC had significant antimicrobial effects in all three groups (adult, infant, and adolescent). Follow-up time analysis showed that AISC was effective in preventing early shunt infections (within 6 months after implant). AISC is more effective in high-risk population (OR, 0.24;95% CI, 0.14-0.40; p=0.60; I2=0%) than in general patient population. Conclusion : The results of meta-analysis indicated that AISC is an effective method for reducing shunt infection. We recommend that AISC should be considered for use in infants and high-risk groups. For adult patients, the choice for AISC could be determined based on the treatment cost.

ACTIVATION ANALYSIS OF ENVIRONMENTAL SAMPLES USING THE MT-25 MICROTRON OF THE FLNR

  • Maslov, O.D.;Belov, A.G.;Starodub, G.Ya.;Dmitriev, S.N.
    • Analytical Science and Technology
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    • v.8 no.4
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    • pp.815-820
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    • 1995
  • Instrumental neutron and gamma activation analysis of coal and combustion products, determination of platinum content in natural samples by radiochemical gamma activation analysis and high-sensitive track method of thorium determination has been studied with the use of the MT-25 microtron.The optimal conditions for complete elemental analysis of coal and combustion products, isolation and determination of platinum and thorium are recommended.

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Streaming Media and Multimedia Conferencing Traffic Analysis Using Payload Examination

  • Kang, Hun-Jeong;Kim, Myung-Sup;Hong, James W.
    • ETRI Journal
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    • v.26 no.3
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    • pp.203-217
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    • 2004
  • This paper presents a method and architecture to analyze streaming media and multimedia conferencing traffic. Our method is based on detecting the transport protocol and port numbers that are dynamically assigned during the setup between communicating parties. We then apply such information to analyze traffic generated by the most popular streaming media and multimedia conferencing applications, namely, Windows Media, Real Networks, QuickTime, SIP and H.323. We also describe a prototype implementation of a traffic monitoring and analysis system that uses our method and architecture.

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An Analysis of Laboratory Instructions in Elementary School Science (초등학교 과학 실험 수업 분석)

  • Yang, Il-Ho;Jeong, Jin-Woo;Hur, Myung;Kim, Young-Shin;Kim, Jin-Soo;Cho, Hyun-Jun;Oh, Chang-Ho
    • Journal of Korean Elementary Science Education
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    • v.25 no.3
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    • pp.281-295
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    • 2006
  • The purpose of this study was to analyze laboratory instructions used in elementary school science lessons by utilizing an analysis instrument for science laboratory instruction(AISLI). This analysis instrument was comprised of 3 elements; the aim of the laboratory activity, the interaction generated, and the inquiry process. There were also a total of 20 sub-categories and its validity was identified at 0.89 by four science educators. For the purposes of this study, 90 laboratory instructions were video-recorded, then transcribed. Laboratory instructions were analyzed by three analyst teams, and the inter-rater reliability within teams was checked through Pearson correlation, with a score of 0.91. The results of this study were as follows: the two principle aims of laboratory activity, namely, to acquire declarative knowledge and to increase attitudes toward science, were observed to be in evidence in 98.9% and 92.2% in laboratory instructions, and the levels of categories of the interaction and inquiry processes were situated at level-1. The implications of these results are that laboratory instructions currently in use do not place sufficient demands upon students' scientific thinking and are not at all conducive to student-centered activities. Therefore in order to remedy this situation, the usefulness of current science laboratory instructions need to be re-evaluated.

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