• 제목/요약/키워드: laboratory analysis

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Association of the PSCA rs2294008 C>T Polymorphism with Gastric Cancer Risk: Evidence from a Meta-Analysis

  • Zhang, Qing-Hui;Yao, Yong-Liang;Gu, Tao;Gu, Jin-Hua;Chen, Ling;Liu, Yun
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권6호
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    • pp.2867-2871
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    • 2012
  • Background: Multiple studies have reported associations between the PSCA rs2294008 C > T polymorphism and GC, but susceptibility has proven inconsistent. Therefore, we estimates the relationship between the rs2294008 C > T polymorphism and GC by meta-analysis. Methods: PubMed, Embase and Web of Science databases were searched and nine independent case-control studies were included in this meta-analysis. Crude ORs with 95% CIs were extracted according to the Mantal-Haenszel method and pooled to assess the strength of the association. Results: We observed that the PSCA rs2294008 C > T polymorphism was significantly correlated with GC risk when all studies were pooled into the meta-analysis. Further subgroup analysis showed the polymorphism to be linked with diffuse and noncardia GC in the allele contrast model, homozygote codominant model, dominant model, and recessive model. However, no connection was apparent for intestinal and cardia GC. In the stratified analysis by ethnicity, significant associations were observed in Asians for the recessive model. Interestingly, the relationship was particularly significant in the Chinese population. Conclusions: Our findings suggest that the PSCA rs2294008 C > T polymorphism is a risk factor for GC, especially in diffuse and noncardia GC and in Chinese.

Effect of Horizontal Adduction Force on Infraspinatus and Deltoid Activities During the Side-Lying Wiper Exercise Using Pressure Biofeedback

  • Kim, Hyun-a;Hwang, Ui-jae;Jung, Sung-hoon;Ahn, Sun-hee;Kim, Jun-hee;Kwon, Oh-yun
    • 한국전문물리치료학회지
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    • 제24권4호
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    • pp.77-83
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    • 2017
  • Background: Shoulder external rotation exercises are commonly used to improve the stabilizing ability of the infraspinatus. Although the side-lying wiper exercise (SWE) is the most effective shoulder external rotation exercise to maximize infraspinatus activity, the effect of adduction force on the infraspinatus and posterior deltoid has not been demonstrated. Objects: This study was conducted to investigate whether horizontal adduction force increases infraspinatus activity and decreases posterior deltoid activity. Methods: Twenty-eight healthy subjects (male: 21, female: 7; $age=23.5{\pm}1.8years$; $height=170.1{\pm}7.4cm$; $weight=69.4{\pm}9.6kg$) were recruited. Subjects were asked to perform the SWE under two conditions: (1) general SWE and (2) SWE with adduction force using pressure biofeedback. Surface electromyography (EMG) signals of the infraspinatus and posterior deltoid were recorded during SWE. Paired t-tests were used to compare the EMG activity of the infraspinatus and posterior deltoid between the two conditions. Results: Posterior deltoid muscle activity was significantly decreased following SWE with adduction force ($7.53{\pm}4.52%$) relative to general SWE ($11.68{\pm}8.42%$) (p<.05). However, there was no significant difference in the infraspinatus muscle activity between the SWE with adduction force ($28.33{\pm}12.16%$) and the general SWE ($26.54{\pm}13.69%$) (p>.05). Conclusion: Horizontal adduction force while performing SWE is effective at decreasing posterior deltoid activity.

Preparation of Bi/Bi2MoO6 Plasmonic Photocatalyst with High Photocatalytic Activity Under Visible Light Irradiation

  • Zou, Chentao;Yang, Zhiyuan;Liang, Mengjun;He, Yunpeng;Yang, Yun;Yang, Shuijin
    • Nano
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    • 제13권11호
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    • pp.1850127.1-1850127.13
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    • 2018
  • Bi metal deposited on $Bi_2MoO_6$ composite photocatalysts have been successfully synthesized via a simple reduction method at room temperature with using $NaBH_4$ as the reducing agent. The photocatalytic activity of the composite was evaluated by degradation of rhodamine B (RhB) and bisphenol A (BPA) solution under visible light. The rate constant of $Bi/Bi_2MoO_6$ composite to RhB is 10.8 times that of $Bi_2MoO_6$, and the degradation rate constant of BPA is 6.9 times of that of $Bi_2MoO_6$. Nitrogen absorption-desorption isotherm proved that the increase of specific surface area is one of the reasons for the improvement of photocatalytic degradation activity of $Bi/Bi_2MoO_6$ composites. The higher charge transfer efficiency of $Bi/Bi_2MoO_6$ is found through the characterization of the photocurrent and impedance, which are attributed to the surface plasmon resonance (SPR) effect produced by the introduction of the metal Bi monomer in the composite. Free radical capture experiments proved that cavitation is the main active species. Based on the above conclusions, a possible mechanism of photocatalytic degradation is proposed.

Molecular characteristics of Budgerigar fledgling disease polyomavirus detected from parrots in South Korea

  • Kim, Sungryong;Kim, Su-Jin;Na, Ki-Jeong
    • Journal of Veterinary Science
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    • 제23권5호
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    • pp.67.1-67.11
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    • 2022
  • Background: Budgerigar fledgling disease polyomavirus (BFDV) is the pathogen that causes budgerigar fledgling disease in psittacine species. The clinical signs of PBFV infection include ascites, hepatitis, and crop stasis. BFDV is associated with a high mortality rate in nestling birds. In contrast, adult birds only have mild symptoms such as feather dystrophy. Objectives: This study aimed to determine the prevalence, genetic characteristics, and phylogenetic analysis of BFDV in pet parrots in Korea. Methods: Fecal and tissue samples were collected from 217 pet parrots from 10 veterinary hospitals including Chungbuk National University Veterinary Hospital. The molecular screening was performed using polymerase chain reaction (PCR) analysis of the small t/large T antigen gene segment. Full-length genome sequencing with the Sanger and phylogenetic analysis were performed on BFDV-positive samples. Results: The PCR results based on the small t/large T antigen gene marker indicated that BFDV DNA was present in 10 out of 217 screened samples. A whole-genome sequence was obtained from six strains and phylogenetic analysis revealed no significant relationship existed between the species and geographical locations amongst them. Conclusions: The prevalence of BFDV infection in South Korea is not high when compared to the prevalence of BFDV in other parts of the world, however, it has been reported sporadically in various species and geographic locations. The whole-genome analysis revealed 0.2%-0.3% variation in intragenomic homogeneity among the six strains analyzed. Korean strains are separately on the phylogenetic tree from their counterparts from China and Japan which might reflect the substantial genetic variation.

Big data platform for health monitoring systems of multiple bridges

  • Wang, Manya;Ding, Youliang;Wan, Chunfeng;Zhao, Hanwei
    • Structural Monitoring and Maintenance
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    • 제7권4호
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    • pp.345-365
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    • 2020
  • At present, many machine leaning and data mining methods are used for analyzing and predicting structural response characteristics. However, the platform that combines big data analysis methods with online and offline analysis modules has not been used in actual projects. This work is dedicated to developing a multifunctional Hadoop-Spark big data platform for bridges to monitor and evaluate the serviceability based on structural health monitoring system. It realizes rapid processing, analysis and storage of collected health monitoring data. The platform contains offline computing and online analysis modules, using Hadoop-Spark environment. Hadoop provides the overall framework and storage subsystem for big data platform, while Spark is used for online computing. Finally, the big data Hadoop-Spark platform computational performance is verified through several actual analysis tasks. Experiments show the Hadoop-Spark big data platform has good fault tolerance, scalability and online analysis performance. It can meet the daily analysis requirements of 5s/time for one bridge and 40s/time for 100 bridges.

Backstepping Control for Multi-Machine Web Winding System

  • Bouchiba, Bousmaha;Hazzab, Abdeldjebar;Glaoui, Hachemi;Med-Karim, Fellah;Bousserhane, Ismail Khalil;Sicard, Pierre
    • Journal of Electrical Engineering and Technology
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    • 제6권1호
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    • pp.59-66
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    • 2011
  • This work treat the modeling and simulation of non-linear dynamic behavior of a web winding process during traction. We designate by a winding process any system applying the cycles of unwinding, transport, treatment, and winding to various flat products. This system knows several constraints, such as the thermal effects caused by the frictions, and the mechanical effects provoked by metal elongation, that generates dysfunctions due to the influence of the process conditions. Several controllers are considered, including Proportional-integral (PI) and Backstepping control. This paper presents the study of Backstepping controls strategy of the winding system. Our winding system is simulated in MATLAB SIMULINK environment, the results obtained illustrate the efficiency of the proposed control with no overshoot, and the rising time is improved with good disturbances rejections comparing with the classical control law.

Limit analysis of 3D rock slope stability with non-linear failure criterion

  • Gao, Yufeng;Wu, Di;Zhang, Fei;Lei, G.H.;Qin, Hongyu;Qiu, Yue
    • Geomechanics and Engineering
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    • 제10권1호
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    • pp.59-76
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    • 2016
  • The non-linear Hoek-Brown failure criterion has been widely accepted and applied to evaluate the stability of rock slopes under plane-strain conditions. This paper presents a kinematic approach of limit analysis to assessing the static and seismic stability of three-dimensional (3D) rock slopes using the generalized Hoek-Brown failure criterion. A tangential technique is employed to obtain the equivalent Mohr-Coulomb strength parameters of rock material from the generalized Hoek-Brown criterion. The least upper bounds to the stability number are obtained in an optimization procedure and presented in the form of graphs and tables for a wide range of parameters. The calculated results demonstrate the influences of 3D geometrical constraint, non-linear strength parameters and seismic acceleration on the stability number and equivalent strength parameters. The presented upper-bound solutions can be used for preliminary assessment on the 3D rock slope stability in design and assessing other solutions from the developing methods in the stability analysis of 3D rock slopes.

Structural damage detection by principle component analysis of long-gauge dynamic strains

  • Xia, Q.;Tian, Y.D.;Zhu, X.W.;Xu, D.W.;Zhang, J.
    • Structural Engineering and Mechanics
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    • 제54권2호
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    • pp.379-392
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    • 2015
  • A number of acceleration-based damage detection methods have been developed but they have not been widely applied in engineering practices because the acceleration response is insensitive to minor damage of civil structures. In this article, a damage detection approach using the long-gauge strain sensing technology and the principle component analysis technology is proposed. The Long gauge FBG sensor has its special merit for damage detection by measuring the averaged strain over a long-gauge length, and it can be connected each other to make a distributed sensor network for monitoring the large-scale civil infrastructure. A new damage index is defined by performing the principle component analyses of the long-gauge strains measured from the intact and damaged structures respectively. Advantages of the long gauge sensing and the principle component analysis technologies guarantee the effectiveness for structural damage localization. Examples of a simple supported beam and a steel stringer bridge have been investigated to illustrate the successful applications of the proposed method for structural damage detection.

Advanced Reactor Passive System Reliability Demonstration Analysis for an External Event

  • Bucknor, Matthew;Grabaskas, David;Brunett, Acacia J.;Grelle, Austin
    • Nuclear Engineering and Technology
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    • 제49권2호
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    • pp.360-372
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    • 2017
  • Many advanced reactor designs rely on passive systems to fulfill safety functions during accident sequences. These systems depend heavily on boundary conditions to induce a motive force, meaning the system can fail to operate as intended because of deviations in boundary conditions, rather than as the result of physical failures. Furthermore, passive systems may operate in intermediate or degraded modes. These factors make passive system operation difficult to characterize within a traditional probabilistic framework that only recognizes discrete operating modes and does not allow for the explicit consideration of time-dependent boundary conditions. Argonne National Laboratory has been examining various methodologies for assessing passive system reliability within a probabilistic risk assessment for a station blackout event at an advanced small modular reactor. This paper provides an overview of a passive system reliability demonstration analysis for an external event. Considering an earthquake with the possibility of site flooding, the analysis focuses on the behavior of the passive Reactor Cavity Cooling System following potential physical damage and system flooding. The assessment approach seeks to combine mechanistic and simulation-based methods to leverage the benefits of the simulation-based approach without the need to substantially deviate from conventional probabilistic risk assessment techniques. Although this study is presented as only an example analysis, the results appear to demonstrate a high level of reliability of the Reactor Cavity Cooling System (and the reactor system in general) for the postulated transient event.

Analytic Study of Acquiring KANSEI Information Regarding the Recognition of Shape Models

  • Wang, Shao-Chi;Hiroshi Kubo;Hiromitsu Kikita;Takashi Uozumi;Tohru Ifukube
    • 한국감성과학회:학술대회논문집
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    • 한국감성과학회 2002년도 춘계학술대회 논문집
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    • pp.266-269
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    • 2002
  • This paper explores a fundamental study of acquiring the users' KANSEI information regarding the recognition of shape models. Since there are many differences such as background differences and knowledge differences among users, they will produce different evaluations based on their KANSEI even when an identical shape model is presented. Cluster analysis is proved to be available for catching a group tendency and for constructing a mapping relation between a description of the shape model and the HANSEl database. In order to investigate an analogical relation and a mutual influence in our consciousness, first, we made a questionnaire that asked subjects to represent images having different colors and shape cones by using 4 pairs of adjectives (KANSEI words). Next, based on the cluster analysis of the questionnaire using a fuzzy set theory, we proposed a hypothesis showing how the analogical relation and the mutual influence work in our mind while viewing the shape models. Furthermore, how the properties of KANSEI depend on their descriptions was also investigated by virtue of the cluster analysis. This work will be valuable to construct a personal KANSEI database regarding the Shape Model Processing System.

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