• 한국수학교육학회지시리즈A:수학교육
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• 제62권3호
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• pp.401-416
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• 2023

본 연구는 기술수용모델을 기반으로 예비교사의 자기효능감과 AI 불안이 수학 수업에서 '똑똑! 수학 탐험대'를 사용하려는 의도에 미치는 영향을 구조적으로 살펴보았다. 이를 위해 254명의 예비교사들의 자기효능감, AI 불안, 인지된 사용 용이성, 인지된 유용성, 사용 의도를 변인으로 연구모형을 설정하고 구조방정식으로 변인 간의 구조적 관계와 직·간접효과를 분석하였다. 분석 결과, 자기효능감은 인지된 사용 용이성, 인지된 유용성, 사용 의도에 유의미한 영향을 미쳤으며, AI 불안은 인지된 사용 용이성과 인지된 유용성에 유의미한 영향을 미치지 않았다. 인지된 사용 용이성은 인지된 유용성과 사용 의도에 유의미한 영향을 미쳤으며, 인지된 유용성은 사용 의도에 유의미한 영향을 미쳤다. 이러한 결과를 통해 수학수업에서 예비교사가 '똑똑! 수학 탐험대' 사용을 촉진하기 위한 시사점과 방안을 제안하였다.

• 한국가구학회지
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• 제18권3호
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• pp.234-242
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• 2007

This study purpose is to design the stand-hangers that can be fabricated conveniently and effectly for manufacture and the market situation of Piwoori Furniture. The study scope is from the research to design prototype in a design process. This study explored the development of knock-down hanger which can be easily assembled and be newly oriented to hanger style. The hangers were made into two main parts with lower part composed as legs, drawers, and containers, and with lower part composed as a shelf and hanger-bear As they are emphasized by the function and usefulness, small sized clothing, underwear, and socks can be stored, and a lot of pants and jackets can be hanged by adjusting the height Therefore, it is not difficult for them to be packed, stored, and transported by being easily assembled and disassembled from the adaption of the knock-down system. Furthermore, the hangers made of the natural wood show the quality of texture and appearance.

• BMB Reports
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• 제56권2호
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• pp.102-107
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• 2023

Genome editing using CRISPR-associated technology is widely used to modify the genomes rapidly and efficiently on specific DNA double-strand breaks (DSBs) induced by Cas9 endonuclease. However, despite swift advance in Cas9 engineering, structural basis of Cas9-recognition and cleavage complex remains unclear. Proper assembly of this complex correlates to effective Cas9 activity, leading to high efficacy of genome editing events. Here, we develop a CRISPR/Cas9-RAD51 plasmid constitutively expressing RAD51, which can bind to single-stranded DNA for DSB repair. We show that the efficiency of CRISPR-mediated genome editing can be significantly improved by expressing RAD51, responsible for DSB repair via homologous recombination (HR), in both gene knock-out and knock-in processes. In cells with CRISPR/Cas9-RAD51 plasmid, expression of the target genes (cohesin SMC3 and GAPDH) was reduced by more than 1.9-fold compared to the CRISPR/Cas9 plasmid for knock-out of genes. Furthermore, CRISPR/Cas9-RAD51 enhanced the knock-in efficiency of DsRed donor DNA. Thus, the CRISPR/Cas9-RAD51 system is useful for applications requiring precise and efficient genome edits not accessible to HR-deficient cell genome editing and for developing CRISPR/Cas9-mediated knockout technology.

• 대한통합의학회지
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• 제8권3호
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• pp.1-10
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• 2020

Purpose : The purpose of this study is to analyze the corrective effect of the general coordinative manipulation (GCM) joint intervention model on distort leg with imbalance of the lower extremity joints, pelvic and shoulder girdles, and lumbar spine. Methods : The study used a comparative analysis of the size of the distort leg and the imbalance of the lower extremity joints, pelvic and shoulder girdles, and lumbar spine before and after the application of the GCM joint intervention model. A total of 31 subjects from movement center G and the department of physical therapy at university M were selected as research subjects, and they were divided into two groups. The GCM joint intervention model was applied to 18 subjects in the bow knee group and 13 subjects in the knock knee group. The two groups received daily intervention three times a week for four weeks. The corrective effect of the GCM joint intervention model for each type of distort leg was compared and analyzed. Results : The effects of the GCM joint intervention model in correcting bow knee and knock knee with knee deformation and imbalance of the lower extremity joints, pelvic and shoulder girdles, and lumbar spine were significant in most domains (p<.05). The correlation between the bow knee and knock knee groups showed significance in most domains (p<.05). Conclusion : The GCM joint intervention model showed significant corrective effect in the bow knee and knock knee groups in terms of knee deformation, lower extremity joints, pelvic and shoulder girdles, and lumbar spine (p<.05).

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2005년도 제20차 학술대회 논문집
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• pp.49-49
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• 2005

• 한국자동차공학회논문집
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• 제14권2호
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• pp.84-91
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• 2006

A heavy duty hydrogen-natural gas fueled engine can obtain stable operation at ultra lean conditions and reduce emissions extremely. Reduction of $CO_2$ in its engine is one of the most benefit. In this study, rate of hydrogen addition($R_{dH2}$) and compression ratio($\varepsilon$) were investigated including performance of this engine. As results, it was found that phenomenon of pressure oscillation when increasing $R_{dH2}$ and $\varepsilon$, it means occurring knock. It consider that pressure oscillation was increased due to fast burning speed of hydrogen. Even if same compression ratio, pressure oscillation was remarkable increased according to increasing $R_{dH2}$. Therefore, limit compression ratio of knock occurring was reduced by increasing $R_{dH2}$.

• Nuclear Engineering and Technology
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• 제48권2호
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• pp.482-494
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• 2016

The Feshbache-Kermane-Koonin (FKK) multi-step direct (MSD) theory of pre-equilibrium reactions has been used to compute the single-step cross-sections for some (p,${\alpha}$) reactions using the knock-on and pick-up reaction mechanisms at two incident proton energies. For the knock-on mechanism, the reaction was assumed to have taken place by the direct ejection of a preformed alpha cluster in a shell-model state of the target. But the reaction was assumed to have taken place by the pick-up of a preformed triton cluster (also bound in a shell-model state of the target core) by the incident proton for the pick-up mechanism. The Yukawa forms of potential were used for the proton-alpha (for the knock-on process) and proton-triton (for the pick-up process) interaction and several parameter sets for the proton and alpha-particle optical potentials. The calculated cross-sections for both mechanisms gave satisfactory fits to the experimental data. Furthermore, it has been shown that some combinations of the calculated distorted wave Born approximation cross-sections for the two reaction mechanisms in the FKK MSD theory are able to give better fits to the experimental data, especially in terms of range of agreement. In addition, the theory has been observed to be valid over a wider range of energy.

• 한국자동차공학회논문집
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• 제3권6호
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• pp.250-261
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• 1995

In this study, a rapid compression and expansion machine(RCEM) equipped with a swirl generator was designed and developed, in order to clarify normal and abnormal combustion(knocking phenomena). This RCEM is intended to simulate combustion process in actual automotive S.I.engines, having a high reproducibility in the compression stroke. Flame propagation and autoignition processes associated with normal and abnormal combustion were captured by the high speed schlieren photography. And swirl intensity. equivalence ratio and ignition position were varied to investigate the effect of turbulence, concentration in the unburnt gas region and flame propagation length. The knock intensity, knock mass fraction and knock mass fraction after autoignition were calculated by use of history of measured cylinder pressure.

• 자연과학논문집
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• 제15권1호
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• pp.57-67
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• 2005

산화적 스트레스에 대한 Bacillus subtilis의 thiol peroxidase 유전자의 생리적인 기능을 연구하기 위해 thiol peroxidase 유전자의 기능이 손상된 녹아웃 돌연변이주를 상동성 재조합에 의해 제조하였다. 호기적 조건에서 배양할 때 야생형과 녹아웃 돌연변이주 사이에는 성장속도에서 차이를 관찰할 수 없었다. 그러나 paraquat 처리할 때와는 달리 $H_2O_2$와 cumene hydroperoxide (CHP)에 의한 산화적 스트레스에 대해 역할을 하고 있음을 시사하는 결과이다.

• 소성∙가공
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• 제12권6호
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• pp.582-587
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• 2003

This paper is concerned with the mechanical property changes of the milli-size products manufactured by forward extrusion processes with square dies. Experiments are carried out with pure aluminum and pure copper billets. Extrusion ratio and knock-out pad are chosen as the important process parameters affecting the changes of mechanical properties such as shear strength and hardness. Shear strength tests with the extruded milli-size pin have shown the strong relation between victors hardness and shear strength in the neck of a stepped pin. As the extrusion ratio increases, the hardness on both the surface and the center line of a pin also increase. It is also noted that the hardness on the surface is a little higher than that on the center. The existence of knock-out pad in extrusion die causes the hardness in the neck of a extruded pin to increase. Finally, the approximated linear relations between shear strength and hardness of a pin are suggested.