• 대한한의학방제학회지
• /
• 제16권2호
• /
• pp.47-69
• /
• 2008

Objectives : The purpose of this study is to inspect trends of the papers of osteoporosis in the field of herbal medicines and to establish the future direction for evaluation and development of natural medicines. Methods : We reviewed 80 oriental medicine papers in Korean journals published between 1994 and 2008. Results : There were 6 review, 2 clinical paper, 72 experimental papers and we confirmed that the drugs used in the experiments are almost yang-invigorating drugs which are good for kidney deficiency pattern Conclusions : We found out some of the herbal extracts are very efficacious for osteoporosis. More studies of oriental medicinal herbs are needed for developing anti-osteoporosis drugs with these basic data.

• 대한한방내과학회지
• /
• 제25권4호
• /
• pp.401-409
• /
• 2004

Aphasia is a dysfunction in recognition and communication, Most instances of aphasia are caused by cerebral disease, especially when a dominant hemisphere is injured. It brings about serious problem in treatment and in directing a therapeutic course for return to social community. A stroke patient who was adimitted Dongguk Bundang Oriental hospital was treated. This subject was diagnosed with Broca Aphasia and Flaccid Tongue(舌?) induced by Yang-deficiency of Kidney(腎陽虛). She was adiministered Jiwhangeumja(地黃飮子) and Scalp acupuncture, and the degree of her aphsia was measured with the Western Aphasia Battery. After three weeks, The patient improved in speaking and general depressed condition.

• 동의생리병리학회지
• /
• 제19권3호
• /
• pp.605-611
• /
• 2005

Chronic fatigue refers to the tiredness which disturbs one's daily activities and lasts more than six months without the sign of improvement by rest or sleep. Male chronic fatigue is included in internal injuries due to overstrain and exhaustion and closely related to river, spleen, stomach and kidney out of five Jang organs. Male chronic fatigue is based on the deficiency of Yang and aggravated by liquor, sex and emotional depression. Chronic fatigue has the following features in Hyungsang ; an inclination for lying: unwillingness to everything; drooping eyes and feeble voice; yellow pale complexion; withered ears; redness on the tip of nose; cheekbone, and lips; blood shot eyes; dryness and loss of hair. Male chronic fatigue usually attacks the persons of horse type and bird type because they are hyperactive compared with what they eat. The following medicines are commonly prescribed for the treatment of male chronic fatigue. Ssangwhatang, Sokunzungtang, and Yanghyulsamultang are commonly prescribed to horse type. Jaumkangwhatang, Chungsimyunzaum, Yookmijiwhangtang to bird type. Palmiwhan, Gozinumja. and Shinkihwan to fish type. Bozungikkitang, Galwhahaesungtang, Samchulgunbitang and Sipjundaebotang to turtle type.

• 한국의사학회지
• /
• 제17권1호
• /
• pp.143-161
• /
• 2004

In Dongeuibogam "東醫寶鑑", Qian Yi(錢乙)'s had been reorganized in more elaborated ways, comprising Ju dan Gae(朱丹溪)'s 'Yang is always sufficient and Yin is always deficient theory(陽有餘陰不足論) and Li Dong Yuan(李東垣)'s 'Theory of the Spleen and Stomach(脾胃論)'. In organizing the contents, 5 Organs(五臟) were mostly concerned especially 'the Heart, the Fire (心火) and the Kidney, the Water(腎水)' as the axis and 'the Spleen and Stomach(脾胃)' as the center of 5 Organs. Based on this concept, the patterns of disharmonies were categorized and the table of content was organized. In this book, 'Deficiency-Excess and Nourishing-Draining(虛實補瀉)'is the basic treatment rule and the concept of 'Yin and Yang(陰陽)' and 'Exterior and Interior(表裏)' is considered to help tell the prognosis. This book has importance of systemizing Qian Yi(錢乙)'s , which was previously mentioned in Hyangyakjipseongbang("鄕藥集成方"),Euibangyoochui("醫方類聚"), Euirimchyalyo("醫林撮要"), by comprising the theories of Jin Yuan Si Da J ia -the four great masters of the Jin Yuan Dynasties(金元四大家).

• 혜화의학회지
• /
• 제16권2호
• /
• pp.217-223
• /
• 2007

Over the period between October 2005 and February 2007, herbal medicine was administered to the patients coming to Dr. Cha Oriental Medical Clinic. As regards the prescription administered to children patients for treating their growth deficiency, Eukmigihwang-tang related to the kidney, the congenital factor, Bojungikgi-tang related to the spleen, the acquired factor. So I administered Eukmigihwang-tang plus Bojungikgi-tang(a union of both herb-remedy: Eukmigihwang-tang and Bojungikgi-tang) The results were obtained as follows. 1. The youngest is six years old, the oldest is thirteen years old. 2. A ratio of male and female children was same. 3. It was shown to be a greater increase than the average value of growth surveyed by the National Statistical Office. 4. It is considered that EukmigihwangtangHapBojungikgitang is effective on child growth.

• Neonatal Medicine
• /
• 제28권2호
• /
• pp.83-88
• /
• 2021

Treatment guidelines for postnatal cytomegalovirus (pCMV) infection in preterm have not been established yet. Neutropenia, thrombocytopenia, hepatitis, colitis, and sepsis-like disease are among the clinical manifestations, which range from moderate to serious. We present a case of autopsy diagnosed as pCMV infection in a premature infant delivered at gestational age of 24 weeks and 5 days. On the 7th and 14th days of birth, urinary CMV polymerase chain reaction samples were negative, ruling out congenital CMV infection. However, autopsy examination revealed that the patient had disseminated pCMV infection. CMV inclusion bodies were found in the majority of tissues, including the lung, liver, pancreas, breast, kidney, and adrenal gland, but not the placenta. The thymus exhibited significant cortical atrophy and T-cell immunodeficiency, possibly induced by dexamethasone treatment for bronchopulmonary dysplasia or by pCMV infection itself. If dexamethasone treatment is extended or high doses are considered, it may be beneficial to test the CMV infection status to prevent aggravation of infection. This case demonstrates that, despite the low prevalence, pCMV infection should be considered a differential diagnosis in preterm if other conditions or etiology cannot justify clinical deterioration.

• Childhood Kidney Diseases
• /
• 제28권2호
• /
• pp.80-85
• /
• 2024

Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare entity characterized by the presence of lupus anticoagulant (LA) and prothrombin (factor II) deficiency. It may cause severe bleeding contrary to classical antiphospholipid syndrome. Here, we report a case of LAHPS presenting with a hemorrhagic ovarian cyst in a 17-year-old girl with systemic lupus erythematosus (SLE) nephritis. She had been followed up for 8 years. Her first manifestation of SLE was prolonged gingival bleeding after tooth extraction at 9 years of age. During the follow-up period, she had neither severe bleeding nor thrombotic complications despite a positive LA and a prolonged activated partial thromboplastin time (aPTT). At this visit, the patient presented with colicky abdominal pain, a hemorrhagic ovarian cyst, a prolonged prothrombin time, a prolonged aPTT, a low factor II level, and a positive LA, leading to the diagnosis of LAHPS. While a hemorrhagic ovarian cyst resolved completely in 3 months, she received oral pill, transfusions of red blood cells and plasma, and intravenous cyclophosphamide pulse therapy in combination with glucocorticoids due to persistent menorrhagia, anemia, prolonged aPTT, and lupus flaring. Thus, LAHPS needs to be considered in SLE patients with positive LA and prolonged aPTT.

• 대한한의학원전학회지
• /
• 제20권2호
• /
• pp.175-193
• /
• 2007

A theory of the school which attach great importance to moxibustion therapy was more developed from 'Ge Hong(葛洪)', 'Wang Tao(王燾)' up to "BianQueXinShu(扁鵲心書)" of 'Dou Cai(竇材)' in Song Dynasty. The first volume of "BianQueXinShu" was described about the principles of health preserving method, diagnosis, treatment related with meridian system, support Yang theory, moxibustion therapy over the 10 chapters and in the continued 3 chapters, explained the symptoms and related moxibustion therapies. The summary is as follows. The Yang energy is the essence of the human body and it is minutely explained in "Hwangdineijing(黃帝內經)". However, the younger scholars after 'Zhang Zhongjing(張仲景)' held different views with "Hwangdineijing" so they didn't control serious diseases. Supporting the Yang energy, it will be possible to human body in good health and long life and perennial youth and longevity. To do like this, the first important thing is a moxibustion, the second is a Taoist hermit medication(丹藥) and the third is well usage of Radix Aconiti Lateralis Preparata. According to the sequence of Yang energy deficiency, the stages of diseases are classified as Ordinary Gi(平氣), Latter deficient state(微虛), The more deficient state(甚虛), Exhausting state(將脫), Exhausted state(已脫) and in the consideration of each stage, it is used gradually with warm-natured berbs, warm-acrid herbs, warm-heated herbs and moxibustion therapy. If it comes to the stage of Exhausted state, the Yang energy is too weak to treat a disease. Therefore it is easy to harm human body with usage the treatment of the Purgationist school theory or the Cold and cool medical school theory, so it is needed a great attention to use these therapies. To summarized the keynote of 'Du Jae''s moxibustion therapy, the one is a minority of selection of points(1$^{\sim}$2 acupuncture points), the second is a majority of moxibustion units(50$^{\sim}$500 units), and the other is a focused selection of points on spleen and kidney(especially Gwanwon, CC4). And in this book, it was explained concretely about the size of moxibustion, according to the experiment with mentioned size, the burning time of moxibustion was almost 4 min 40 sec, so the big size moxibustion was one of the characteristic of moxibustion therapy revealed in this book. Also it was used 'Suseongsan(睡聖散)' - a kind of analgesic herb complexes - to reduce a pain during the usage of moxibustion therapy in this book. To develop the moxibustion theory, it is more investigated in the future that there wasn't significant relation between Gwanwon(CC4) and spleen and kidney meridian in theory, compared to many used Gwanwon(CC4) in the prescription, where as mentioned the importance of spleen and kidney in treatment, that considering the burning time(1 unit - 4 min 40 sec, 12 units an hour, maximum 288 units a day) there were no guidances about meals, sleeping, stool and urine, and that there was no concrete study about the toxicity of 'Suseongsan' as analgesic moxibustion therapy.

• Childhood Kidney Diseases
• /
• 제2권1호
• /
• pp.14-19
• /
• 1998

목적 : 최근 6개월 이하의 영아에서 저칼슘혈증의 임상 경험의 예가 증가하여 이의 원인, 증세, 치료 및 임상 경과를 알아보기 위하여 본 연구를 시행하였다. 방법 : 1994년 2월 부터 1991년 4월까지 경북대학교 병원 소아과에 경련을 주소로 내원하였던 환아 중 그 원인이 저칼슘혈증으로 확인되었던 11예를 대상으로 하였다. 이들은 모두 6개월 이하였으며 평균 $2.2{\pm}1.1$개월이었다. 이들 환아의 병력지를 통하여 후향적으로 각종 검사를 분석하였다. 결과 : 이 환아들의 저칼슘혈증의 원인으로는 비타민 D 결핍이 8예였고, 무기인의 과다한 섭취가 3예였다. 경련의 양상은 전신성 간-근대성이 9예였고 부분 근대성이 2례였다. 경련의 지속시간은 30초에서 20분까지 다양하였으며, 경련의 횟수는 평균 6.5회였다. $Bonky^{(R)}$, 칼슘 단독 또는 병합 요법 후 혈청 칼슘은 치료 전 $6.3{\pm}0.9$ mg/dL서 치료 후 $9.9{\pm}1.7$ mg/dL로 통계학적으로 의미있게 증가하였고(P=0.0008), 혈청 ALP는 치료 전 $1,418{\pm}864$ U/L에서 치료후 $772{\pm}503$ UL로 통계학적으로 의미있게 감소하였다(P=0.0112). 입원 당시 iPTH은 $176.7{\pm}129$ pg/mL로 증가되어 있었고 3명의 환아에서 치료 이후 추후 검사상 정상 범위로 회복 되었다. 모든 환아에서 치료 전$25(OH)D_3$는 감소되어 있었으며 평균 $3.9{\pm}2.7$ ng/mL였고, 치료 후 1예에서 정상으로 회복되었다. $1,25(OH)_{2}D_{3}$는 6예 중 2예에서 감소되어 있었다. 결론 : 최근 비타민 D가 보강된 것으로 알려진 조제 분유 영양아에서 발생된 경련을 동반한 저칼슘혈증의 원인은 상당수에서 비타민 D 결핍이었으며 $1,25(OH)_{2}D_{3}$의 단기간 투여로 성공적으로 치료되었으며, 조제 분유 영양아에서도 저칼슘혈증의 원인으로 비타민 D 결핍을 반드시 생각해야 한다고 사료 된다.

• 동의생리병리학회지
• /
• 제29권5호
• /
• pp.378-385
• /
• 2015

Dizziness is one of the most common symptoms in clinical practice. The purpose of this study was to investigate the characteristics of patients with dizziness who visited Korean medicine hospital. This study analyzed 328 patients with dizziness who visited Dunsan Korean Medicine Hospital of Dae-Jeon University from Nov. 1st, 2012 to Oct. 31st, 2014. We gathered the data of the patients based on the medical charts. The patients were divided into 4 gorups ; central dizziness group, peripheral dizziness group, presyncope dizziness group, functional dizziness group, In the distribution according to sex, the number of female patients was higher than the male patients in all the types of dizziness except the presyncope group. The average age of the central group was higher than any other types. The peripheral and central group were most frequently admitted. The average hospitalization period were categorized as follows : central group 37.31, presyncope group 17, functional group 14.21, peripheral group 13.5 days. The following numbers of patients showed the distribution of each syndrome differentiation ; deficiency of qi and blood(氣血兩虛) 58.8%, plegm-dampness syndrome(濕痰中阻) 18.0%, hyperactivity of liver yang(肝陽上亢) 14.3%, deficiency of kidney essence(腎精不足) 8.8%. The distribution of herbal medicine for dizziness were categorized as follows ; Jaeumkeonbi-tang(Ziyinjianpi-tang, 滋陰健脾湯) 50.4%, Banhabaekchulcheonma-tang(Banxiabaishutianma-tang, 半夏白朮天麻湯) 10.2% and Bojungikgi-tang(Buzhongyiqi-tang, 補中益氣湯) 4.1%. The 86.0% of patients with dizziness has improved. The peripheral showed highest rate of improvement(100%). This report would serve as a reference data for further study about patients with dizziness in the clinical field of Korean medicine.