• Journal of radiological science and technology
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• v.43 no.5
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• pp.353-357
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• 2020

IVR procedures are on the rise, and patient doses are on the rise. It is necessary to evaluate fluoroscopy dose in IVR procedure. Evaluate ESD on IVR equipment as a reference to DRL settings, I would like to present the direction of improvement in the ESD rate test criteria for fluoroscopy dose. The experimental method is measured with 6cc ionization chamber under the 20cm PMMA Phantom. Radiation is subject to abdominal procedure. The average dose rate of the incident surface was 21.6 ± 11.4 mGy/min. The highest dose equipment was 58.5 mGy/min, and there was no equipment exceeding the domestic standard of 100 mGy/min. However, there were five units above 50 mGy/min. To reduce fluoroscopy dose, it is recommended to reduce pulse rate, The dose increases as the image receptor ages. It is recommended to modify the domestic inspection criteria to 50 mGy/min.

• The Korean Journal of Applied Statistics
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• v.22 no.5
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• pp.1033-1046
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• 2009

In new drug development studies or clinical trials, zero-dose control is needed in general to determine the lowest dose level for a new drug which can act with our bodies. When the lowest dose level compared with zero-dose control has significant difference in effect, it is referred as minimum effective dose(MED). We propose, in this paper, parametric sequential test using updated control to identify the minimum effective dose(MED) level. Monte Carlo Simulation is adapted to examine the power and experimental significance levels of the proposed method with other methods.

• Journal of Preventive Medicine and Public Health
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• v.38 no.4
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• pp.431-436
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• 2005

Objectives : We investigated the seroprevalence of the measles antibody and its at tributable factors for the students who underwent routine 2-dose Schedule Era. Methods : The subjects were 996 students of the national measles seroepidemiologic study in December 2000 who had vaccination records. We conducted a questionnaire survey and we performed serologic testing for the measlesspecific IgG by using an enzyme linked immunosorbent assay. Results : The coverage for the first dose of the MMR vaccination at 12-15 months of age was 95.1% and the coverage for the second dose of MMR at 4-6 years of age was 35.0%. The proportion of subjects undergoing 2-dosesof MMR dec reased as the age of the subjects increased. The seropositive rate of the measles antibody was significantly high in the second dose vaccinees (93.5% in the second dose group, 84.7% in the non-second dose group, p<0.001) and it was 72.0% in the 0-dose group, 85.4% in the 1-dose group and 93.7% in the 2-dose group (p<0.001). Two point eight percent of the subjects had a past history of measles infection. On the multiple logistic regression analysis, the first and second dose (odds ratio, 8.54; 95% CI.=3.05-23.91), the first dose (odds ratio, 3.06; 95% CI.=1.20-7.81) and the outbreak in the year 2000 (odds ratio, 1.89; 95% CI.=1.24-2.88) were the significant factors for the seropositivity. Conclusions : Maintaining high coverage with a 2-dose vaccination program would be the decisive factor to prevent an outbreak of measles and to eliminate measles in Korea.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2006.08a
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• pp.135-135
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• 2006

• The Korean Journal of Pain
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• v.18 no.2
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• pp.124-132
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• 2005

Background: This study was performed to evaluate the dose-related effects of naloxone on morphine analgesia in the rat formalin test, and observe the correlation of pain behavior and spinal c-fos expression induced by a formalin injection. Methods: Fifty rats were divided into five groups; control, morphine (morphine pre-treated, intra-peritoneal injection of 0.1 mg of morphine 5 min prior to formalin injection), and three naloxone groups, which were divided according to the administered dose-ratio of naloxone to morphine 20 : 1 ($5{\mu}g$), 10 : 1 ($10{\mu}g$), and 1 : 1 ($100{\mu}g$) representing the low-, medium-, and high-dose naloxone groups, respectively, were injected intra-peritoneally 16 min after a formalin. A fifty ul of 5% formalin was injected into the right hind paw. All rats were observed for their pain behavior according to the number of flinches during phases 1 (2-3, 5-6 min) and 2 (1 min per every 5 min from 10 to 61 min). The spinal c-fos expression was quantitatively analyzed at 1 and 2 hours after the formalin injection using a real-time PCR. Results: The morphine pre-treated (morphine and three naloxone) groups during phase 1, and the morphine, low- and medium-dose naloxone groups during phase 2, showed significantly less flinches compared to those of the control (P < 0.05). In the three naloxone groups, the numbers of flinches were transiently reduced following the naloxone injection in the low- and medium-dose groups compared to those of the morphine group (P < 0.05). The duration of the reduced flinches was longer in the medium-dose group (P < 0.05). The high-dose group revealed immediate increases in flinches immediately after the naloxone injection compared to those of the morphine, low- and medium-dose groups (P < 0.05 for each). The spinal c-fos expression showed no significant patterns between the experimental groups. Conclusions: Our data suggest that relatively low-dose naloxone (1/20 to 1/10 dose-ratio of morphine) transiently potentiates morphine analgesia; whereas, high-dose (equal dose-ratio of morphine) reverses the analgesia, and the spinal c-fos expression does not always correlate with pain behavior in the rat formalin test.

• Progress in Medical Physics
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• v.1 no.1
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• pp.51-60
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• 1990

Dose distributions around Co- 60 moving source in high dose rate remote afterloading unit, Buchler 3K unit, were experimented with X-omat V films and calculations. In our experiments, film dosimetries have achieved to evaluated the axial dose distributions for source oscillations were 0, 3.5, 5.0 and 6.0 cm in periodically, In results, the dose distributions in axial of source movement showed apparently higher than in transverse direction caused by source locations, dwelling time and air gap in the applicator. In the calculations, the dose rate was derived by using the inverse square law, filteration corrections and Meisberger constant for scatter corrections as source movings. In our experiments and calculations, the average dose uncertainties were showed -2.1$\pm$1.9% in fixed sourdce, -2.9$\pm$1.8%, -7.4$\pm$6.1% and -6.7$\pm$4.6% at 3.5 cm, 5.0 cm and 6.0 cm source oscillations, but the calculations have showed very close to experimental dose rate within 4 cm distance from source.

• Korean Journal of Digital Imaging in Medicine
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• v.13 no.1
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• pp.1-6
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• 2011

The purpose of our study was to determine the entrance surface dose and absorbed dose in ovary when using the metal speculum and plastic speculum in hysterosalpingography respectively. The examinations was performed in anthropomorphic phantom into which calibrated photoluminescence glass dosimeter were placed on symphysis pubis level surface and ovary area. We checked average fluoroscopy time and spot expose times during the hysterosalpingography. It was average fluoroscopy time 58 sec, spot expose 5 times. We divided the subjects into two different groups to used metal and plastic speculum. We measured 10 times of absorbed dose in the same condition of the anthropomorphic phantom. We compared two groups adsorbed dose on ovary with speculum material-related. The entrance surface dose on of plastic Speculum using group was average 17.23 mGy, absorbed dose on ovary was average 3.51 mGy. The entrance surface dose on ovary of metal Speculum using group was average 19.95 mGy, absorbed dose on ovary was average 4.14 mGy. Plastic speculum using group shows a decrease absorbed dose(17.9%) as compared with metal speculum using group. The method of plastic speculum using in hysterosalpingography. might provide us with lower radiation dose, especially in patients with childbearing stage.

• Nuclear Engineering and Technology
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• v.54 no.10
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• pp.3849-3854
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• 2022

The present work aims to optimize the radiation protection efficiency for ion-selective containers used in the liquid treatment for the nuclear power plant (NPP) cooling cycle. Some naturally occurring rocks were examined as filler materials to reduce absorbed dose and equivalent dos received from the radioactive waste container. Thus, the absorbed dose and equivalent dose were simulated at a distance of 1 m from the surface of the radioactive waste container using the Monte Carlo simulation. Both absorbed dose and equivalent dose rate are reduced by raising the filler thickness. The total absorbed dose is reduced from 7.66E-20 to 1.03E-20 Gy, and the equivalent dose is rate reduced from 183.81 to 24.63 µSv/h, raising the filler thickness between 0 and 17 cm, respectively. Also, the filler type significantly affects the equivalent dose rate, where the redorded equivalent dose rates are 24.63, 24.08, 27.63, 33.80, and 36.08 µSv/h for natural rocks basalt-1, basalt-2, basalt-sill, limestone, and rhyolite, respectively. The mentioned results show that the natural rocks, especially a thicker thickness (i.e., 17 cm thickness) of natural rocks basalt-1 and basalt-2, significantly reduce the gamma emissions from the radioactive wastes inside the modified container. Moreover, using an outer cementation concrete wall of 15 cm causes an additional decrease in the equivalent dose rate received from the container where the equivalent dose rate dropped to 6.63 µSv/h.

• Journal of Korean Society on Water Environment
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• v.20 no.4
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• pp.376-381
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• 2004

The use of electron beam irradiation was investigated to disinfect total coliforms in the secondary sewage treatment effluent. Unchlorinated secondary effluent was irradiated at different dose of 0.2~1.0 kGy by 1 MeV, ELV-4 Model electron beam accelerator. It is interesting to note that a 100 % reduction in total coliforms and total colonies were achieved until a dose of approximately 0.8 kGy. Even at low dose of 0.2 kGy, the total coliforms and total colonies were successfully inactivated to the level of satisfying the new effluent discharge guideline. Besides disinfection of total coliforms, approximately a 50% removal in biochemical oxygen demand was pronounced at a dose of 0.2 kGy. More than 20 % removal in suspended solids and turbidity was also observed at a dose of 1.0 kGy. The application of electron beam irradiation appeared to be one of options to reuse sewage treatment effluent as agricultural or industrial water.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.23 no.10
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• pp.826-830
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• 2010

This study examined the effect of the scattering dose on the thyroid during a mammography examination. One hundred subjects for a mammography examination were enrolled in this study. The average glandular dose (AGD) and thyroid scattering dose (TSD) were measured. Statistical analysis was carried out using the percentage, t-test and co-variance. The mean radiation exposure to the breast and thyroid was $1.08{\pm}0.16$ and $0.14{\pm}0.04$ mGy, respectively. The percentage TSD to the AGD was 31.19%. There was no difference between the Rt. and Lt., and CC to MLO, and radiation dose to the TSD was 13.78% of the breast. Therefore, the volume of radiation exposure to the thyroid was 54.12% in a single routine mammography examination. These results suggest that the TSD was increased by increasing radiation dose to the breast. A thyroid protector is considered necessary to decrease the level of radiation exposure.