• BMB Reports
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• 제48권1호
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• pp.19-24
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• 2015

A mouse homozygous for the spontaneous mutation uncovered (Uncv) has a hairless phenotype. A 309-bp non-frameshift deletion mutation in the N-terminal cytoplasmic domain of iRhom2 was identified in Uncv mice ($iRhom2^{Uncv}$) using target region sequencing. The detailed molecular basis for how the iRhom2 mutation causes the hairless phenotype observed in the homozygous $iRhom2^{Uncv}$ mouse remains unknown. To identify differentially expressed proteins in the skin of wild-type and homozygous $iRhom2^{Uncv}$ littermates at postnatal day 5, proteomic approaches, including two-dimensional gel electrophoresis and mass spectrometry were used. Twelve proteins were differentially expressed in the skin in a comparison between wild-type and homozygous $iRhom2^{Uncv}$ mice. A selection of the proteomic results were tested and verified using qRT-PCR, western blot and immunohistochemistry. These data indicate that differentially expressed proteins, especially KRT73, MEMO1 and Coro-1, might participate in the mechanism by which iRhom2 regulates the development of murine skin.

• Korean Journal of Acupuncture
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• 제32권4호
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• pp.190-198
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• 2015

Objectives : Through comparison between Mawangdui Silk Manuscripts and Huangdi's Internal Classic, this study aimed to put an emphasis on clinical significance of Yin-yang theory in Meridians. Methods : We investigated the documents recorded in Yin Yang Shi Yi Mai Jiu Jing, Zu Bi Shi Yi Mai Jiu Jing and Miraculous Pivot to compare of the character of meridian names. Results : In the naming of meridians, three yin and three yang were accepted earlier than Viscera and Bowels. Three yin and three yang play important role in relation with division of a human body. Conclusions : It is necessary to focus on the importance of Yin-yang theory in meridian system.

• The International Journal of Costume Culture
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• 제13권1호
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• pp.37-41
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• 2010

It is a universal phenomenon for people to establish ideal images of man according to a specific time, society and race. Thus, people have invested endless endeavor to reach the standard of ideal image. Especially, they made efforts to embody the ideal image of man as a perfect human image using appearance feature like a human body and clothing. Shi jing(詩經) is considered as a very valuable source book which reveals the life style, customs, thinking, ideas, and emotion of people of that period. The purpose of this study is to analyze the ideal image of man and woman which ancient Chinese pursued, focusing Shi jing(詩經). The results are as following. The ideal image of man is nice, handsome, dignified, generous and gentle. Besides, he should have adequate sense of humor, tall height. clear eye, broad forehead, moderate and upright behavior, outstanding horsemanship and marksmanship and braveness. Meanwhile, the ideal image of woman was described as gentle, decent, and graceful. Also, she should have tall height, light complexion, pretty hand, long neck, broad forehead, clear eyes, and charming black hair. The ideal beauty of woman included nobility and elegant personality in addition to the good physical appearance.

• Journal of Acupuncture Research
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• 제20권1호
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• pp.61-73
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• 2003

Objective: The purpose of this study is to compare Sa-Am's Ohaeng-acupuncture(舍巖五行鍼法) with Linqi-aupuncture(六氣鍼法)-the transforms of Sa-Am's Ohaeng-acupuncture. Methods : Zheng Ge(正格), Sheng(勝格), Han Ge(寒格), Re Ge(熱格) of Sa-Am's Ohaeng-acupuncture compared with Liuqi-acupuncture(六氣鍼法)-therapy form invigoration and purgation of five zang-fu's wind. heat, dapness, dryness and cold(風熱濕燥寒). Results: 1. Liuqi-acupuncture used five-su points(五兪穴) and Zi-Ta Jing Bu Xie(自他經補瀉). 2. Liuqi-acupuncture is reinforced or reduced itself-point of itself-meridian(自經自穴) in therapy for invigoration and purgation. 3. Liuqi-acupuncture is therapy for invigoration and purgation of five zang-fu's wind, hear, dampness, dryness and cold(風熱濕燥寒). 4. Zheng Ge is similar to Bu-fa, Sheng Ge is similar to Xie-fa in Qu-xue of Ta-jing. The Qu-xue of interrestraining relations is the same, but that of interdependent relation is the difference in Qu-xure of Zi-jing. 5. Han Ge and Re Ge is similar to Re Bu Xie fa in Qu-xue fo Zi-jing but is different to in Ta-zing. For example, Han Ge is Shaofu(Bu), Yingu(Xie) but Re Ge is Shaofu(Xie), Yingu(Bu).

• 대한한방내과학회지
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• 제20권1호
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• pp.48-56
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• 1999

This study has been carried out to investigate Brain in Nei-jing. The results of this study were as follows. 1. Kidney energy becomes the marrow by warm caring function of Meong-mun(命門) and the marrow becomes brain by ascending and gathering between a hole Back-hoi(百會) and a hole pung-ji(風池) 2. Brain is a sea of the marrow that five vital organs are eraporated togather. 3. In Nei-jing(內經), there is a explanation the connectin between brain and mind, thanking by drawing in a concept of head. 4. Brain regulrates physical excercise. 5. There is a direct connection between brain and biosis. 6. Brain achieves function of sense, relating with the five sensory organs. 7. Brain controls a change of emotion. 8. Brain has immunological function.

• 대한한의학원전학회지
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• 제28권4호
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• pp.57-63
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• 2015

Objectives : Through the analysis of the harmonization(和) thought in Traditional Chinese culture, and then excavate the theory and application of Harmonization Method(和法) in Huang Di Nei Jing(黃帝內經) and Shanghan Zabing Lun(傷寒雜病論). Methods : We find the harmonization(和) means harmony and neutral in traditional Chinese culture, including the harmony of society, the harmony of the mind and the body, and so on. Results : Huang Di Nei Jing(黃帝內經) emphasized the health status is moderate, the disease state is unbalance, preserving our health should keep the yin-yang equilibrium, treating disease should reestablish the equilibrium status, which establish the foundation of the theory of Harmonization Method(和法). Shanghan Zabing Lun(傷寒雜病論) created the methods of settlement and harmony, which is a precedent for the wide application of Harmonization Method(和法) for future generations, including to reconcile the interior-exterior and yin-yang, to harmony the ying-wei and qi-blood, to reconcile the activities of qi of internal organs. Conclusions : The harmonization(和) is the ideological foundation of the theory system of TCM and the Harmonization Method(和法). The Harmonization Method(和法) is an important treatment method for clinical practice of Traditional Chinese Medicine.

• Journal of Acupuncture Research
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• 제19권1호
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• pp.210-224
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• 2002

Objective : A study on $\ll$Maek-beop$\gg$ which is the first scription of pulse diagnosis method in history. Method : A translation of contents in $\ll$Maek-beop$\gg$ into modern concepts on the basis of researched books and the explanation of difficult characters and paragraphs to general concepts. Result : The pulse diagnosis method by comparison, moxibustion method, venesection method, a treatment of an abscess and the succession of treatment in $\ll$Maek-beop$\gg$ are delivered from $\ll$Sumen, 素問$\gg$, $\ll$Lingchui, 靈樞$\gg$. Conclusion : A $\ll$Maek-beop$\gg$ is the scription of the diagnosis of meridian and therapeutic method in $\ll$Zu bi shi yi mai jiu jing, 足臂十一脈灸經$\gg$, $\ll$yin yang shi yi mai jiu jing, 陰陽十一脈灸經$\gg$.

• 동의신경정신과학회지
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• 제25권4호
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• pp.371-382
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• 2014

Objectives: The purpose of this study is to examine the test-retest reliability and to suggest methods to enhance reliability. Methods: Participants consisted of 145 patients with generalized anxiety disorder who were diagnosed by the Structured Clinical Interview for DSM-IV Axis I Disorders. Participants were tested twice within one week. Results: The test-retest reliability of the Instrument of Pattern Identification for Jing Ji and Zheng Chong was examined in 145 patients and it was calculated as 0.3919. Internal Reliability of each part was calculated as 0.320~0.502. Reliability and concordance rate of symptoms are presented in the table. Frequency of symptoms and correlation between weight and frequency are also presented in the table. Conclusions: Based on these results, we have modified the Instrument of Pattern Identification for Jing Ji and Zheng Chong.

• 대한한의학원전학회지
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• 제32권1호
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• pp.75-93
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• 2019

Objectives : This study is to reveal the origin of Mingtangyangfutu in "YiXueRenMen". Methods : This study compares and analyzes it with MingTang diagrams in reference books of "YiXueRenMen", MingTang diagrams and diagrams of bronze statues for acu-moxibustion in those days. Results : The origins of Mingtangyangfutu cannot be found in the citations. The argument that it is copied and simplified from MingTang diagrams in "JinLanXunJing(金蘭循經)" lacks its grounds. As MingTang diagrams in "TongRenShuXueZhengJiuTuJing" and "ZhenJiuJuYing" have less information than it, they were nothing more than references when it drew. Apparel of man, the first acupoint, the last acupoint and orders of acupoints of their meridians in it are different from ones in MingTang diagrams and diagrams of bronze statues for acu-moxibustion. Conclusions : Mingtangyangfutu is not a copied and simplified version of MingTang diagrams in "JinLanXunJing", but is one to add new information for MingTang diagrams in "TongRenShuXueZhengJiuTuJing", "ZhenJiuJuYing", or has a separate rationale (Gajeongdongin(嘉靖銅人) related to at the time.

• 대한한의학원전학회지
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• 제20권2호
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• pp.147-174
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• 2007

"Theory on the Sufficiency of Yang and the Deficiency of Yin(陽有餘陰不足論)" mainly instituted as follows: The 'Yang Qi(陽氣)' of the heaven(天) has changed to 'Qi(氣)', and the 'Yin Qi(陰氣)' of the earth(地) has changed to 'Xue(血)', 'Qi(氣)' is always sufficient and 'Xue(血)' is always deficient. 'The Always Sufficient Qi(氣常有餘)' means 'the fire always exists(常有火)', and 'the fire(火)' is 'the premier fire(相火)'. 'The premier fire(相火)' is always in men's body and causes 'activities(動)' which is the core characteristic in men's life, and in other side it always has opportunities to be made symptoms by 'the abnormal activities of the premier fire(相火妄動)'. In 'the always deficient Xue(血常不足)' , 'Xue(血)' is the 'Yin Qi(陰氣)' of liver and kidneys[肝腎] which is attached by 'the premier fire(相火)', as it means 'Xue(血)' and 'Jing(精)'. He suggested that 'the premier fire(相火)' is the power of human life, but if 'the premier fire(相火)' is not based on 'Yin Qi(陰氣)', it can not fulfill its function. So he thought that the maintenance and fulfillment of 'Yin Qi(陰氣)' is very important. In conclusion, "Theory on the Sufficiency of Yang and the Deficiency of Yin(陽有餘陰不足論)" explains the basic character of men's life which 'Dong Duo Jing Shao(動多靜少)', so 'the premier fire(相火)' which control 'the activities(動)' is always being and 'Jing Xue(精血)' which control 'Jing(靜)' is always scare.