• Korean Journal of Pharmacognosy
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• v.31 no.3
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• pp.306-309
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• 2000

Two sesquiterpene lactones were isolated from methanol extracts of the whole plants of Youngia japonica (L.) DC. by the silica gel column chromatography and recrystallization. On the basis of spectrometric studies including $^1H-NMR,\;^{13}C-NMR,\;DEPT,\;^1H-^1H\;COSY,\;^{13}C-^1H\;COSY$, IR and MS, compounds 1 and 2 were identified as derivatives of 10(14)-guaien-12, 6-olide, isoamberboin and isolipidiol, respectively. This is the first report on the isolation of isoamberboin and isolipidiol from Youngia japonica (L.) DC.

• Korean Journal of Pharmacognosy
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• v.32 no.3 s.126
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• pp.238-241
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• 2001

The leaves and flowers of Hemisteptia lyrata Bunge (Compositae) have been used for cure sour throat and treat tumors in traditional chinese medicine. As a result of the chemical investigation, two compounds were isolated from the $CHCl_3$ extract of the flowers of H. lyrata. On the basis of spectroscopic experiments, their structures were identified as 8-hydroxy-3-keto-10(14)-guaien-12,6-oxide (Isoamberboin) and 3,8-dihydroxy-4(15),10(14),11(13)-guaiatrien-12,6-oxide (8-Hydroxyzaluzanin C). They were first isolated from the genus Hemisteptia.