Purpose : To investigate clusterin expression in the acini and ductal cells of rat submandibular glands after Co-60 gamma irradiation. Materials and Methods : The male Sprague-Dawley rats weighing approximately 250 gm were divided into control and experimental groups. The experimental group was irradiated with a single absorbed dose of 2, 5, 10, and 15 Gy on the head and neck region. All the rats were sacrificed at 1, 3, 7, 14, 21, and 28 days after irradiation. The specimens including the submandibular gland were sectioned and observed using a immunohistochemical method. Results : In the 2 Gy group, clusterin expression was similar to that of the control group at 1 day after irradiation and it was observed in the striated ductal cells at 3 days after irradiation. In the 5 Gy group, clusterin expression was observed in the striated ductal cells at 1 day after irradiation and gradually increased in the 10 and 15 Gy groups. In the 15 Gy group, clusterin expression was prominent in the striated ductal cells at 1 day after irradiation, but it gradually decreased with the experimental period. The destruction of the striated ductal cells was observed in the 2 Gy group at 21 days after irradiation and in the 5, 10, and 15 Gy groups at 7 days after irradiation. The destruction of the acinar cells was observed in the 2 Gy group at 28 days after irradiation and in the 5, 10, and 15 Gy groups at 14 days after irradiation. Conclusion : Clusterin expression was induced by low doses of irradiation and it appeared to be involved in the regulation of cellular response to irradiation.
A survey was conducted to examine the knowledge and acceptance of food irradiation in order to provide baseline data required in the development of food irradiation education programs for college students. 150 students majoring in food and nutrition or food technology in the Chungnam National University were chosen for a survey. The results are as follows. First, college students' knowledge about food irradiation is scanty. Knowledge assessment showed that 56% of the participants had previously heard of food irradiation. 68% of the respondents thought that radioactivity remains in food after irradiation and 25.3% of them were not sure whether radioactivity remains in food after irradiation or not. Only half of the respondents thought that nutrient loss due to irradiation is equal to or lower than that due to cooking or freezing. Second, approximately 56% of the respondents showed that food irradiation is somewhat or strongly needed for meat or fish; whereas, over 60% of them showed that food irradiation is not needed for grain, vegetable and fruit. Almost 40% of the respondents were seriously concerned about irradiation of vegetables and fruits; whereas, they showed less concern about spice irradiation. More than half of the respondents were not willing to use irradiated food in all the six food groups. Third, the correlation analysis showed that the need of food irradiation is negatively correlated with concerning about the irradiated fish and fruits, but positively correlated with willingness to use irradiated food in all the five food groups, except in spices. Concern about the irradiated food is negatively correlated with willingness to use irradiated food from all the six food groups. Fourth, almost all the respondents (over 90%) agreed that the irradiated food labeling is required as well as the development of proper methods to identify irradiated foods.
The purpose of the study was to investigate the effects of the single and fractionated irradiation on the microvascular structure of the submandibular gland in rats. For this study, 90 Sprague-Dawley strain rats were irradiated to their neck region with equal split doses of 9Gy for a 4 hours interval and 15Gy single dose by 6MV X-irradiation and sacrificed on the 1st, 3rd, 7th, 14th and 27th day after irradiation. The author observed histological changes at Hematoxylin and Eosin staining and PAS staining under a light microscope, and also observed distribution and structural changes of the microvasculature in rat submandibular gland using a scanning electron microscope by forming vascular resin casting. The results were as follows: 1. In the light microscopic examination, the microvasculature was slightly dilated and decreased in number on the 1st day after irradiation, and increase in number of microvasculature was observed on the 3rd day after irradiation. And then distribution of microvasculature was markedly increased on the 7th day after iradiation, but decreased on th 14th day after irradiation again. Such changes were greater in the single irradiated group than in the fractionated irradiated group. 2. The reaction to PAS staining on glandular cell was decreased on the 1st and the 3rd day after irradiation, and recovered on the 7th day after irradiation. The reaction was decreased on the 14th day after irradiation again, and recovered on the 28th day after irradiation. Changes were more apparent in the single irradiated group. 3. In the scanning electron microscopic examination, early changes of microvasculature were decreased capillary density, dilation of conduits and meandering. Increased capillary dentsity or anastomosis due to vascular reproduction and smooth curved running were observed on the 7th and 14th day after irradiation. Decreased capillary and smooth running tendency were observed on the 28th day after irradiation again. Such changes were greater in the single irradiated group than in the fractionated irradiated group.
In this thesis, output voltage, current and power of solar module were classified by irradiation from data of overall operating characteristics collected for one year in order to manage efficient photovoltaic generation system and deliver maximum power. In addition, from these data, correlations between irradiation of photovoltaic cell and amount of power given by photovoltaic cell was quantitatively examined to deduce optimization of the design and construction of photovoltaic generation system. As I-V characteristics according to a temperature range of 10~50[$^{\circ}C$], the area of I-V characteristics were increased with an increase in temperature. Since this area corresponds to the power, output power is thought to have increased with temperature. As output power characteristics according to a temperature range of 10~50[$^{\circ}C$], output power was increased with an increase in temperature. Since output power increases with temperature increase, the result corresponds well to the related equation on temperature and output power. As I-V characteristics according to a irradiation range of 100~900 [$W/m^2$], voltage and current were increased with an increase in irradiation. The result is thought of as an increase in output power with increasing irradiation. As output power characteristics according to a irradiation range of 100~900 [$W/m^2$], output power was increased with increasing irradiation. This result corresponds well to the related equation on irradiation and output power.
Transactions on Electrical and Electronic Materials
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제11권5호
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pp.226-229
/
2010
Many methods exist that promote wound healing, including light therapy, which consists of light beams that assist the human body in treating and sterilizing wounds, as well as regenerating cells. Irradiation with specific wavelengths of either laser or LED light has been shown to induce beneficial proliferation of fibroblasts that, depending on the size of the wound, can be effective in promoting wound healing. The experiments in this study utilized 8 week old 250~300 g Male Sprague Dawley Rats (ILAR Code: NTacSam:SD) and included a non-irradiation group and a 525 nm green LED irradiation group (n of each group = 7). In experiments animals were allowed to rest for 24 hours after wounds had been excised, which was followed by non- irradiation or 525 nm green LED irradiation therapy one hour per day for 9 days. Immunohistochemical staining was conducted for cytokeratin in order to precisely measure the defect size. In addition, Masson's trichrome staining was utilized in order to compare levels of collagen between the 525 nm green LED irradiation group and the non-irradiation group. Animals exposed to 525 nm green LED irradiation (p<0.05) healed at a faster rate and had increased collagenosis compared with the non-irradiated control group. Thus, treatment with 525 nm green LED irradiation had a beneficial effect on wound healing and should be considered as a possible alternative to low power laser treatment.
The purpose of this study was to improve dye effect and method in order to facilitate the use of persimmon juice dyeing. Silk fabrics were pad-dyed to 100% pick-up using padding machine after dipping in persimmon juice extracted from unripe persimmons indigenous to Jeju. The color of dyed silk fabrics by padding method was more even and repeatable than that by traditional hand method. Persimmon juice concentrations were 4 types 10, 25, 50 and 100%. The silk fabrics were pad-dyed to 100% pick-up and were repeatedly dyed two times and three times with 100% concentration. The higher the concentration, the more color deepened. UV Irradiation instead of sunlight was applied to color developing. Irradiation times were shortened to 1-8hrs. Color values which reguired 30-50 hrs. in sunlight irradiation. were obtained in 3-5 hrs. with UV irradiation. Tensile strengths of silk fabrics in UV irradiation decreased but not decreased in sunlight irradiation. Elongations of silk fabrics in sunlight irradiation increased but decreased in W irradiation. Drape stiffness increased up to three times.
Radiological and clinical evidences indicate that hyperthermia combined with irradiation produce a significant improvement in therapeutic effect of cancer The experiences obtained from 90 rats' kidney A single dose of irradiation ranged from 6Gy, 8Gy and 10Gy was delivered on the rat's kidney. The combined therapy group had the same irradiation after hyperthermia at $42\~44^{\circ}C$ for 30 minutes. Microscopic examination and calculation of thermal enhancement ratio were carried out, and the results were as follows: 1. In the group of hyperthermia alone, there were moderate glomerular congestion and mild tubular degeneration on light microscopic examination. 2. In the group of irradiation alone, tubular degeneration was noted in 6Gy irradiation and its severity was increased along with radiation dose. 3. In the group of hyperthermia combined with irradiation, tubular degeneration and necrosis were appeared in 6Gy and 10Gy irradiation, respectively. 4. On electron microscopic examination, proximal convoluted tubular and glomerular changes in irradiation group were similar to that of combined with hyperthermia, and its severity was increased along with observation periods. 5. Thermal enhancement ratio (TER) was 1.0 after evaluation of histipathologic changes in rat's kidney, with combination therapy.
Postharvest diseases cause considerable losses to harvested fruits and vegetables worldwide. Fresh produce suspected of harboring postharvest disease must be treated to control any pathogens present. Although there are various treatments to control postharvest losses by pathogens, the current community is eager to take safer and more eco-friendly alternatives to help with human health and reduce environmental risks. Ionizing irradiation is a promising phytosanitary treatment that has a significant potential to control postharvest diseases in use worldwide. Although almost 19000 metric tons of sweet potatoes and various fruits are irradiated each year in six countries to control postharvest disease, irradiation continues to be a debate, with slow acceptance by industries. Irradiation alone is not effective as a fungicide, and an over dose affects the physical properties of irradiated products. A combination of irradiation with other treatments such as heating, biocontrol agents, chlorination, and nano Ag particles is to enhance their effectiveness. Challenges to the use of phytosanitary irradiation are an avoidance of irradiated postharvest and cost of the irradiation facilities, and thus consumers still need to be educated on the principles and benefits of irradiation and prepare an optimum economy of scale for commercial use. In this review, we evaluated the current phytosanitary irradiation, and combination with various other treatments to minimize the postharvest losses.
Selecting graphite grades with superior irradiation characteristics is important task for designers of graphite moderation reactors. To provide reference information and data for graphite selection, the effects of irradiation on three fine-grained, iso-molded nuclear grade graphites, ETU-10, IG-110, and NBG-25, were compared based on irradiation-induced changes in volume, thermal conductivity, dynamic Young's modulus, and coefficient of thermal expansion. Data employed in this study were obtained from reported irradiation test results in the high flux isotope reactor (HFIR)(ORNL) (ETU-10, IG-110) and high flux reactor (HFR)(NRL) (IG-110, NBG-25). Comparisons were made based on the irradiation dose and irradiation temperature. Overall, the three grades showed similar irradiation-induced property change behaviors, which followed the historic data. More or less grade-sensitive behaviors were observed for the changes in volume and thermal conductivity, and, in contrast, grade-insensitive behaviors were observed for dynamic Young's modulus and coefficient of thermal expansion changes. The ETU-10 of the smallest grain size appeared to show a relatively smaller VC to IG-110 and NBG-25. Drastic decrease in the difference in thermal conductivity was observed for ETU-10 and IG-110 after irradiation. The similar irradiation-induced properties changing behaviors observed in this study especially in the DYM and CTE may be attributed to the assumed similar microstructures that evolved from the similar size coke particles and the same forming method.
Choo, Kee Nam;Yang, Seong Woo;Park, Seng Jae;Shin, Yoon Taeg
Nuclear Engineering and Technology
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제53권1호
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pp.344-350
/
2021
As the High Flux Advanced Neutron Application Reactor (HANARO) has been recently required to support new R&D relevant to future nuclear systems requiring a much higher neutron fluence, the development of irradiation capsule technology for long-term irradiation testing was performed in three steps (3, 5, 10 dpa). At first, several design improvements of a standard capsule were suggested based on a failure analysis of the capsule and successfully applied for irradiation testing at HANARO at up to eight reactor operation cycles equivalent to 3 dpa. Based on a schematic stress analysis of the vulnerable parts of the previous capsule, an optimized design of the capsule was made for 5 dpa irradiation. The newly designed capsule was safely out-pile tested up to 450 days, which was equivalent to 5 dpa irradiation in the reactor. The test results were submitted to the Reactor Safety Review Committee of HANARO and irradiation testing for 5 dpa was approved. The capsule was also successfully out-pile tested to evaluate the possibility of irradiation testing for 10 dpa. For a higher neutron fluence exceeding 10 dpa, new capsule technologies, including a new capsule that has a different bottom design and neutron flux boosting capsule, were also suggested.
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