• Title/Summary/Keyword: ipc

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Isopinocampheylhaloborane-Methyl Sulfide as Hydroborating and Stereoselective Reducing Agent

  • 차진순;민수진;김종미;권오운;김은주
    • Bulletin of the Korean Chemical Society
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    • v.16 no.1
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    • pp.37-42
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    • 1995
  • Reactions of alkenes and alkynes with the recently discovered isopinocampheylhaloborane-methyl sulfide (IpcBHX·SMe2, X=Cl, Br, I) were investigated in detail in order to establish their usefulness as hydroborating agents. The reagents readily hydroborated alkenes at 50 ℃ and alkynes at 25 ℃ with excellent regioselectivity in placing the boron atom exclusively at the less hindered carbon atom. Especially, the selectivity achieved by the iodo derivative reaches essentially 100%. In addition to that, IpcBHX·SMe2 was applied to the reduction of cyclic ketones to examine its stereoselectivity. The halogen substituent in these reagents plays an important role in the stereoselective reduction. The stereoselectivity increased dramatically with increasing steric size of the substituent. Finally, the iodo derivative achieved highly stereoselective reduction, such selectivity being comparable to that previously achieved with trialkylborohydrides.

Accessibility of Electronic Publishing Technology Trends (전자출판의 접근성 관련 기술 동향 분석 - 특허정보분석을 중심으로-)

  • Jang, Bo-Seong;Nam, Young-Jun
    • Proceedings of the Korean Society for Information Management Conference
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    • 2014.08a
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    • pp.115-118
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    • 2014
  • 본 연구는 특허정보의 제목 및 초록에 나타난 장애인을 위한 전자출판의 접근성 기술 동향을 분석하고자 관련 유효특허를 수집 분석하였다. 분석내용은 특허 출원 빈도, IPC 주제분류, 전자출판 접근성 기술 분류 기준에 의한 세부 기술별 출원 동향, 주제어 출현 빈도 등을 파악하였다. 연구결과 장애인의 전자출판 접근성 분야는 출원 건수가 증가하는 전형적인 성장기 단계이며, IPC 주제분류는 섹션G(물리학), 섹션H(전기)영역에서 주로 특허가 출원되고 있으며 세부 기술별 출원 동향은 문자를 점자로 변환 압축 및 관련 보조공학기기 개발 특허 등이 중심적으로 나타났다. 출현 빈도수를 기준으로 한 상위 주제어는 braille, display, device, tactile, character, control 순으로 나타났다.

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Network Analysis of Technology Convergence on Decentralized Energy by Using Patent Information : Focused on Daegu City Area (특허정보를 활용한 분산형 에너지 기술융합 네트워크 분석 : 대구지역을 중심으로)

  • Han, Jang-Hyup;Na, Jung-Gyu;Kim, Chae-Bogk
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.3
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    • pp.156-169
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    • 2016
  • The objective of this study is to investigate patent trends of Daegu city which tries to introduce environment friendly energy and to develop new technology or new industry sprung from technology convergence on smart decentralized energy technology and other technologies. After applying network analysis to corresponding groups of technology or industry convergence, strategy for future energy convergence industry is provided. Patent data applied in Daegu city area are used to obtain research goal. The technology which contains several IPC codes (IPC Co-occurrence) is considered as a convergence technology. Path finder network analysis is used for visualizing and grouping by using IPC codes. The analysis results categorized 13 groups in energy convergence industry and reclassified them into 3 cluster groups (Smart Energy Product Production Technology Group, Smart Energy Convergence Supply Technology Group, Smart Energy Indirect Application Technology Group) considering the technical characteristics and policy direction. Also, energy industry has evolved rapidly by technological convergence with other industries. Especially, it has been converged with IT industry, and there is a trend that energy industry will be converged with service industry and manufacturing industry such as textile, automobile parts, mechanics, and logistics by employing infrastructure as well as network. Based on the research results on core patent technology, convergence technology and inter-industry analysis, the direction of core technology research and development as well as evolution on decentralized energy industry is identified. By using research design and methodology in this study, the trend of convergence technology is investigated based on objective data (patent data). Above all, we can easily confirm the core technology in the local industry by analyzing the industrial competitiveness in the macro level. Based on this, we can identify convergence industry and technology by performing the technological convergence analysis in the micro level.

Nitric Oxide-cGMP-Protein Kinase G Pathway Contributes to Cardioprotective Effects of ATP-Sensitive $K^+$ Channels in Rat Hearts

  • Cuong, Cang Van;Kim, Na-Ri;Cho, Hee-Cheol;Kim, Eui-Yong;Han, Jin
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.2
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    • pp.95-100
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    • 2004
  • Ischemic preconditioning (IPC) has been accepted as a heart protection phenomenon against ischemia and reperfusion (I/R) injury. The activation of ATP-sensitive potassium $(K_{ATP})$ channels and the release of myocardial nitric oxide (NO) induced by IPC were demonstrated as the triggers or mediators of IPC. A common action mechanism of NO is a direct or indirect increase in tissue cGMP content. Furthermore, cGMP has also been shown to contribute cardiac protective effect to reduce heart I/R-induced infarction. The present investigation tested the hypothesis that $K_{ATP}$ channels attenuate DNA strand breaks and oxidative damage in an in vitro model of I/R utilizing rat ventricular myocytes. We estimated DNA strand breaks and oxidative damage by mean of single cell gel electrophoresis with endonuclease III cutting sites (comet assay). In the I/R model, the level of DNA damage increased massively. Preconditioning with a single 5-min anoxia, diazoxide $(100\;{\mu}M)$, SNAP $(300\;{\mu}M)$ and 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate (8-pCPT-cGMP) $(100\;{\mu}M)$ followed by 15 min reoxygenation reduced DNA damage level against subsequent 30 min anoxia and 60 min reoxygenation. These protective effects were blocked by the concomitant presence of glibenclamide $(50\;{\mu}M)$, 5-hydroxydecanoate (5-HD) $(100\;{\mu}M)$ and 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate, Rp-isomer (Rp-8-pCPT-cGMP) $(100\;{\mu}M)$. These results suggest that NO-cGMP-protein kinase G (PKG) pathway contributes to cardioprotective effect of $K_{ATP}$ channels in rat ventricular myocytes.

A Study on the Statistical Analysis of Korea Patent Information (한국특허정보의 통계분석에 관한 연구)

  • Uhm, Dai-Ho;Chang, Young-Bae;Jeong, Eui-Seop
    • Journal of Information Management
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    • v.41 no.3
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    • pp.27-44
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    • 2010
  • Most research about patent data analyzes the trend of technologies using a Patent Map(PM), and suggests the frequencies and trend of patents in a certain topic using tables or graphs in Excel. However, more advanced analysis tools are recently needed to compare the trends among national and international industries. This research discussed why statistical analysis is needed to improve the reliability in PM analysis, and the research compares the trends of patents in Korea between 1990 and 2004 by years, International Patent Classification(IPC) sections, and countries using the frequencies and Poisson regression model. The statistical analysis is also suggested and applied to R&D studies.

Effects on Changes in Femoral Vein Blood Flow Velocity with the Use of Lower Extremity Compression for Critical Patients with Brain injury (하지압박요법이 중증 뇌손상 환자의 대퇴 정맥 혈류 속도변화에 미치는 영향)

  • Kim, Jung-Sook;Kim, Hye-Jung;Woo, Yun-Hee;Lym, Ji-Young;Lee, Chul-Hyung
    • Journal of Korean Academy of Nursing
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    • v.39 no.2
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    • pp.288-297
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    • 2009
  • Purpose: This study was done to evaluate the mean venous velocity (MVV) response with knee and thigh length compression stockings (CS) versus intermittent pneumatic compression (IPC) devices in immobile patients with brain injuries. Methods: We carried out a randomized controlled study. We analyzed both legs of a randomly chosen sample of 43 patients assigned to one of 4 groups (86 legs). The patients were sequentially hospitalized in the intensive care unit (ICU) in "S hospital" from November 2005 to December 2006. The base line and augmented venous velocity was measured at the level of the common femoral vein. We applied leg compression 42 times over 7 days (for 2 hours at a time at 2 hour intervals). Results: There was a statistical difference among the 4 groups. The difference for the "IPC" group was more significant than the "CS" group. Conclusion: These results indicate that the application of IPC can be considered as an effective method to prevent deep vein thrombosis for immobile patients with brain injury.

Survey of Intellectual Property Rights in the Ergonomics Field in Korea

  • Park, Jemo;Hwang, Jung Bo;Jung, Hwa Shik
    • Journal of the Ergonomics Society of Korea
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    • v.34 no.5
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    • pp.487-499
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    • 2015
  • Objective: The purpose of this study was to analyze the trend of ergonomics field in overall intellectual property rights in Korea, and suggest the direction for the future development. Background: Many ergonomists are trying to pursue optimal human well-being and safety, and create more convenient designs for human use. For these reasons, intellectual property rights may be used to protect the legitimate rights of originative and innovative ergonomic designs. Method: Intellectual property rights were reviewed by using Korea Intellectual Property Rights Information Service (KIPRIS), and then were classified and analyzed according to three intellectual property rights (patent, utility model, design), International Patent Classification (IPC) and ergonomics application areas. Results: The total number of intellectual property rights registered in the ergonomics field in terms of three intellectual property rights (patent, utility model, design) showed 48,814 which occupied 5.97% of the total registered Korea's intellectual property rights. Within three intellectual property rights, patent (87%) was recorded overwhelmingly higher than utility model (9%) and design (4%). Conclusion: The current trend of patent, utility model and design in the ergonomics field in Korea tend to increase over time. It is suggested based on the analysis in this study that continuing research and development should be focused on electricity section in accordance with the global trend. Application: The results of this study can direct the ergonomists to the areas of intellectual property rights in the ergonomics field that should focus on the research and development in terms of three intellectual property rights, IPC and ergonomics application areas.

Analysis of Patent Technology Trend of Domestic Brassiere (국내 브래지어 특허기술동향 분석)

  • Jeong, Eunyeong;Kwak, Seongyeong;Park, Soonjee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.44 no.2
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    • pp.321-341
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    • 2020
  • This study analyzed the domestic patent trends of brassiere to provide fundamental data for promising technology. Relevant patents were searched by inputting the key words of "brassiere" and IPC code "A41C" on patent information search service of KIPRIS. A search for bras patents from 1985 to 2019 revealed 533 registered applications out of the total 744 listed. The IPC code with the highest portion (40%) was A41C3/00 (brassiere), followed by A41C3/14 (forming inserts, 21.6%), and A41C3/12 (component parts, 13.3%). To arrange the guidelines of the content of brassiere patents, we carried out a qualitative technology analysis on 744 patents, to extract 850 technology cases applied in patents. From the technological features of each case, main categories were classified into two parts (function and structure) and function was divided into 7 sub-categories that included physiological comfort, physical comfort, utility, healthcare, appearance, and economic value. As for the structure, cup showed the highest portion (37.9%), followed by pad (16.5%), and wings (13.2%). From the aspect of function, appearance showed the highest portion (30.8%), followed by usability (22.2%), physiological comfort (14.6%), physical comfort (14.6%), economic value (10.7%), and health care (7.4%).