• Korean Journal of School Psychology
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• v.17 no.2
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• pp.199-222
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• 2020

This study was conducted to verify the effects of socially prescribed perfectionism on depression as mediated by intolerance of uncertainty and either ruminating or reflective response styles, on as will as to find ways to effectively address depression as it presents in university students. For this purpose, 283 university students at the central region were assesed using data collected from the following surveys: the Center for Epidemiological Studies-Depression Scale(CES-D), the Multidimensional Perfectionism Scale(HMPS), the Intolerance of Uncertainty Scale(IUS), and the Response to Depressed Mood Questionnaire(RDQ) and that were used to collect data. The results of this study are as follows. First, there was a positive correlation between the Intolerance of uncertainty and the rumination response style to the uncertainty of socially prescribed perfectionism, but not correlation the reflective response mode. Second, with respect to the relationship between socially prescribed perfectionism and depression, intolerance of uncertainty was set as the primary mediator variable and the rumination response style were set as the secondary mediator variables. The results shown to have a significant mediating effects. However this mediating effect was not significant when, in order to verify the mediating effect, we set the secondary mediator variable as the reflective response style. These results suggest that to prevent depression that manifests as socially prescribed perfectionism, it may be effective to intervene with a focus on the intolerance of uncertainty and the rumination response style. Finally, the implications and limitations of the study are discussed based on the results.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.17 no.5
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• pp.95-104
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• 2022

This study aims to find out the influence of the intolerance of uncertainty on entrepreneurial intention by focusing on the start-up support system awareness. While most of existing studies focused on the positive psychological variables and individual environmental characteristics influencing on the entrepreneurial intention, this study has taken a look at the influence of the intolerance of uncertainty as the psychological variable to the entrepreneurial intention to negatively act on the entrepreneurial intention. As a result of the analysis, the intolerance of uncertainty under the control of entrepreneurship and gender is shown to have the negative (-) influence on the entrepreneurial intention and has high level of recognition on the start-up support system perception, and the start-up support system perception is confirmed to have positive (+) influence on the entrepreneurial intention. And, it also indicates that, with respect to the influence of the intolerance of uncertainty on the entrepreneurial intention, the start-up support system perception has the partial medium effect. Following this result of the study, it provides following indications: First the existing studies on the entrepreneurial intention had not covered the intolerance of uncertainty but it is confirmed as the psychological variable with negative influence on the entrepreneurial intention. Second, it is feasible for the preliminary start-up businesses may turn the fear on start-up failure into positive entrepreneurial intention with the start-up support system perception as the leading vehicle. And, third, based on the result, the government should enhance the start-up support system perception even more by seeking ways of efficient publicity to enable more preliminary start-up businesses to participate in diverse start-up support policies. Lastly, it discusses the limitations of this study as well as proposal for ensuing study plans.

• Journal of Dairy Science and Biotechnology
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• v.38 no.1
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• pp.1-18
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• 2020

Lactose intolerance is a pathophysiological phenomenon caused by a deficiency of the enzyme lactase present in human intestines. Changes in intestinal digestion and colon fermentation after the intake of lactose-containing products cause diarrhea and other clinical discomforts. Therefore, lactose intolerance can be easily ameliorated by consuming lactose hydrolyzed milk and dairy products. In the recent years, lactose-free dairy products have provided lactose intolerant consumers with several options, due to an improvement in the quality and an increase in the variety of products. Currently, the manufacturing of lactose-free products also represents the fastest growing sector in the dairy industry. This review, thus, aims to provide an overview of the current availability and prospects of lactose-free dairy products, and also discuss the potential benefits of the development of a variety of lactose-free dairy foods.

• Korean Journal of Biological Psychiatry
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• v.21 no.3
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• pp.87-92
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• 2014

Objectives Risk taking has been implicated in the development of various psychiatric disorders. Previous studies have indicated that risk taking behavior is associated with high levels of impulsiveness. Risk taking entail uncertain situation that outcome probability is unknown. This study tested impulsivity, intolerance of uncertainty and risk taking behavior. Methods A total of 73 participants completed a test battery comprised of the UPPS-P scale as a psychometric measurement of five dimensions of impulsivity, Intolerance of Uncertainty Scale, and Balloon Analog Risk Task (BART) as a behavioral measure of risk taking. The Pearson correlation analysis was used. Results The sensation seeking factor was positively correlated with BART measure (r = 0.27, p = 0.02). Specifically, the relationship between sensation seeking and BART was significant in females. Conclusions Among the five factors of UPPS-P, only the sensation seeking factor predicts risk taking propensity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.338-344
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• 2020

Intolerance of Uncertainty is associated with numerous psychopathologies, including generalized anxiety disorders. However, several studies differ in the factor structures applicable for the Intolerance of Uncertainty Scale (IUS), and there exists a debate regarding the factorial and construct validity. Thus, in the current study, the IUS was newly translated to explore and verify the structures and factors relative to the cultural background of Korea. The study involved an exploratory factor analysis of randomly extracted data from 260 of 533 adults selected. Results determined that a prospective factor of 3 items and inhibitory factor of 5 items was appropriate. In addition, a confirmatory factor analysis and correlation analysis of the remaining 273 data revealed that a structural model comprising of the 8-items two factors model was well suited (x²=37.699, TLI=0.951, CFI=0.969, RMSEA=0.063, SRMR=0.039), and showed significant static correlation with worry, depression, and state-trait anxiety.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.6
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• pp.545-553
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• 2019

Purpose: Feeding tolerance is extremely important in preterm infants. This study aimed to evaluate whether preterm infants receiving Lactobacillus reuteri DSM 17938 would develop fewer symptoms of feeding intolerance. Secondary outcomes were duration of parenteral nutrition, time to reach full feeding, length of hospital stay, sepsis, necrotizing enterocolitis (NEC), diarrhea, and mortality. Methods: This double-blind randomized controlled trial of L. reuteri DSM 17938 versus placebo included 94 neonates with a gestational age of 28-34 weeks and birth weight of 1,000-1,800 g. Results: Feeding intolerance (vomiting and/or distension) was less common in the probiotic group than in the placebo group (8.5% vs. 25.5%; relative risk, 0.33; 95% confidence interval, 0.12-0.96; p=0.03). No significant intergroup differences were found in proven sepsis, time to reach full feeding, length of hospital stay, or diarrhea. The prevalence of NEC (stages 2 and 3) was 6.4% in the placebo group vs. 0% in the probiotic group (relative risk, 1.07; 95% confidence interval, 0.99-1.15; p=0.24). Mortality rates were 2.1% in the probiotic group and 8.5% in the placebo group, p=0.36). Conclusion: The administration of L. reuteri DSM 17938 to preterm infants was safe and significantly reduced feeding intolerance. No significant differences were found in any other secondary outcomes.

• Safety and Health at Work
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• v.10 no.3
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• pp.362-369
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• 2019

Background: Chronic nonspecific symptoms attributed to indoor nonindustrial work environments are common and may cause disability, but the medical nature of this disability is unclear. The aim was to medically characterize the disability manifested by chronic, recurrent symptoms and restrictions to work participation attributed to low-level indoor pollutants at workplace and whether the condition shares features with idiopathic environmental intolerance. Methods: We investigated 12 patients with indoor aire-related work disability. The examinations included somatic, psychological, and psychiatric evaluations as well as investigations of the autonomic nervous system, cortisol measurements, lung function, and allergy tests. We evaluated well-being, health, disability, insomnia, pain, anxiety, depression, and burnout via questionnaires. Results: The mean symptom history was 10.5 years; for disabling symptoms, 2.7 years. Eleven patients reported reactions triggered mainly by indoor molds, one by fragrances only. Ten reported sensitivity to odorous chemicals, and three, electric devices. Nearly all had co-occurrent somatic and psychiatric diagnoses and signs of pain, insomnia, burnout, and/or elevated sympathetic responses. Avoiding certain environments had led to restrictions in several life areas. On self-assessment scales, disability showed higher severity and anxiety showed lower severity than in physician assessments. Conclusion: No medical cause was found to explain the disability. Findings support that the condition is a form of idiopathic environmental intolerance and belongs to functional somatic syndromes. Instead of endless avoidance, rehabilitation approaches of functional somatic syndromes are applicable.

• The Journal of Korean Academic Society of Nursing Education
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• v.28 no.3
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• pp.328-339
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• 2022

Purpose: This study was conducted to identify the mental health status of Korean adults during the COVID-19 pandemic and to verify the predictors and mediating effects of avoidance coping on the relationship between the intolerance of uncertainty and anxiety and the intolerance of uncertainty and depression. Methods: An online survey was completed by 191 Korean adults from 19 to 64 years old. Using the IBM SPSS Win 19.0 program, the data were analyzed through the frequency, mean, t-test or analysis of variance, Pearson's correlation coefficient, linear regression analysis and Sobel test. Results: Of the survey respondents 21.5%, and 33.5% respectively were classified into anxiety and depression risk groups. The predictors of anxiety were intolerance of uncertainty (β=.52), avoidance coping (β=.21), and response efficacy (β=-.15). Those variables explained 47.7% of the respondents' anxiety. The predictors of depression were intolerance of uncertainty (β=.40), avoidance coping (β=.20), and response-efficacy (β=-.12). These variables explained 34.9% of the participants' depression. Among the predictors of anxiety and depression, avoidance coping was the significant mediating variable. Conclusion: The predictors of anxiety and depression during the COVID-19 pandemic were revealed to be intolerance of uncertainty, avoidance coping, and response-efficacy. These results indicate the necessity of providing the cognitive interventions and reducing the use of avoidance coping strategies on a personal level. Community-level efforts, including early detection and health communication strategies, should prioritize risk groups for example young adults. The study suggests it will be necessary to provide sufficient information, psychological support and economic policy alternatives related to the COVID-19 pandemic on the national level.

• Herbal Formula Science
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• v.31 no.3
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• pp.203-213
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• 2023

Objectives : The purpose of this study is to report the symptomatic relief effect of a herbal prescription combined with methimazole for hyperthyroidism caused by Graves' disease. Methods : After diagnosis of hyperthyroidism, methimazole was initially administered alone. As the clinical symptoms continued, a herbal medicine combining Gamiondam-tang and Cheongsimyeonja-eum was administered together with methimazole. Blood concentrations of hormones were measured, and the degree of clinical symptoms was measured using the NRS scale. The effect of herbal medicine on heat intolerance was analyzed by Wilcoxon rank sum test, and the relationship between thyroid hormone and heat intolerance was analyzed by Pearson's correlation coefficient. Results : Heat intolerance symptoms were significantly reduced when the herbal prescription was administered in parallel than when methimazole was administered alone (w=296, p=0.001). The decrease in heat intolerance was not related to thyroid hormone levels (p=0.27, 0.37). Conclusions : It was found that the herbal medicine combining Gamiondam-tang and Cheongsimyeonja-eum was effective in treating hyperthyroidism symptoms including heat intolerance.

• Journal of Dairy Science and Biotechnology
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• v.27 no.2
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• pp.55-62
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• 2009

Milk is called an almost complete food in terms of nutrition, especially for the younger generations because it contains a number of nutrients required for growth and development. Lactose intolerance is defined as a malabsorption of lactose in the intestine with some typical symptoms of abdominal pains and bloating, and occurred at 75% of global populations, which hampers milk consumption worldwide. Lacks of milk consumption in the underdeveloped countries frequently lead to many nutrients deficiencies, so that diseases including osteoporosis, hypertension, and colon cancer are more prevalent in the recent days. Lactose in foods needs to be hydrolyzed prior to intestinal absorption. The hydrolytic enzyme responsible for splitting lactose into its monomeric forms, glucose and galactose, is called as lactase or $\beta$-galactosidase. The former is primarily used as blood sugar and energy source and the latter used in glycolipid synthesis of brain tissues in infants. Lactose is clinically diagnosed with the breath hydrogen production test as well as intestinal biopsy. Reportedly, symptoms of lactose intolerance are widely prevalent at 25% of Europeans, 50 to 80% of Hispanics, South Indians, Africans, and Jews, almost 100% of Asians and native Americans. For the adults, phenotype of lactase persistence, which is able to hydrolyse lactose, is more common in the northern Europeans, but in the other area lactase non-persistence or adult-type hypolactasia is dominant. Genetic analysis on human lactase gene continued that lactase persistence was closely related to the err site of 1390 single nucleotide polymorphism from the 5'-end. To alleviate severity of lactose intolerance symptoms, some eating patterns including drinking milk a single cup or less, consumption along with other foods, whole milk rather than skimmed milk, and drink with live yogurt cultures, are highly recommended for the lactose maldigesters. Also, delay of gastric emptying is effective to avoid the symptoms from lactose intolerance. Frequency of lactose intolerance with conventional diagnosis is thought overestimated mainly because the subjects are exposed to too much lactose of 50 g rather than a single serving amount. Thus simple and accurate diagnostic method for lactose intolerance need to be established. It is thought that fermented milk products and low- or free lactose milks help improve currently stagnant milk consumption due to lactose intolerance which contributes to major barrier in milk marketing especially in Asian countries.