• Journal of Life Science
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• v.17 no.11
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• pp.1587-1592
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• 2007

Locus control region (LCR) is a cia-acting element which regulates the transcription of genes in developmental stage and/or tissue-specific pattern. Typically, LCR consists of several DNase I hypersensitive sites (HSs), where the binding motifs for transcriptional activators are present. The binding of activators to the HSs recruits chromatin modifying complexes to the LCR, opening chromatin structure and modifying histones covalently through the locus. LCR forms close physical contact with target gene located at a distance by looping away intervening region. In addition, non-coding RNA is transcribed from LCR toward target genes in continuously acetylated active domain. These structural and functional features of LCR suggest that the LCR plays many roles in chromatin activation and transcriptional regulation.

• Journal of Information Technology Applications and Management
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• v.13 no.4
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• pp.181-195
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• 2006

In recent years, increasing attention has been paid on how to manage a successful relationships between the receiver and provider of the Information Systems(IS) outsourcing services. This study explores the sources of influence for successful outsourcing relationships. Based on the Jaworski's control combination model for marketing, we (1) propose a management combination model of outsourcing relationships where trust is introduced as an intervening variable and outsourcing compleyity as a moderating variable, (2) test this model using a sample of 94 outsourcing projects in 36 organizations that have outsourced there IS functions to external service providers. The results indicated several significant findings. First, the deployment of management mechanism such as contract mechanism and trust building has a significant effect on the outsourcing success through trust only. Second, complexity of outsourcing activities has a moderating effect on relationship management combinations.

• Korean Journal of Community Nutrition
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• v.2 no.5
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• pp.671-679
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• 1997

Community nutritionists draw upon theories from the social sciences to improve their work in health promotion and disease prevention. Social science theories are sets of concepts that provide systematic explanations that can predict events or situations, and are classified into several paradigms and worldviews. these theories interact with research and practice around the subject matter of community nutrition. Use of these theories provides benefits in community nutrition by helping to organize thinking about nutrition topics in ways that are useful for assessing , understanding, intervening, and evaluation community nutrition issues. Community nutrition researchers and practitioners can be choose from many available social science theories by evaluating assumptions, scope, applicability, complexity, effectiveness, and other aspects of the theories. Awareness and use of social science theories should enhance the development of community nutrition. (Korean J Community Nutrition2(5) : 671-679, 1997)

• Journal of Korean Society for Quality Management
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• v.35 no.1
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• pp.35-51
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• 2007

In terms of company management for market segmentation and creating new market opportunity, Blog service has much important meanings. This study was designed to investigate the casual relationship among service quality, service value, customer satisfaction, and customer loyalty in the given blog service site "Cyworld". Through the empirical results, specific factors of blog service quality were discovered to be amusement, interaction, customization, reliability and convenience. Also rte confirmed that service value intervening between blog service quality and customer satisfaction plays an important role. This paper presents much implications both theoretical and practical side.

• Bulletin of the Korean Chemical Society
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• v.9 no.3
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• pp.133-135
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• 1988

Kinetics and mechanism of the nucleophilic substitution reactions of phenacyl bromides with anilines in methanol-acetonitrile mixtures at $45.0^{\circ}C$ are reported. The reaction is found to proceed via $S_N2$ process, but the magnitudes of cross interaction constants, ${\rho}_{XY}$, between substituents X in the nucleophile and Y in substrate were unusually small, even after allowing for the fall off due to non-conjugative intervening -CO group in the reactant. As in the other phenacyl derivatives, the resonance shunt phenomenon was invoked to explain the remarkable diminuation of the $|{\rho}_{XY}|$ values.

• Korean Journal of Remote Sensing
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• v.10 no.2
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• pp.63-82
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• 1994

Multitemporal analysis with remotely sensed data is complicated by numerous intervening factors, including atmospheric attenuation and occurrence of clouds that obscure the relationship between ground and satellite observed spectral measurements. A reconstruction system was developed to increase the discrimination capability for imagery that has been modified by residual dffects resulting from imperfect sensing of the target and by atmospheric attenuation of the signal. Utilizing temporal information based on an adaptive timporal filter, it recovers missing measurements resulting from cloud cover and sensor noise and enhances the imagery. The temporal filter effectively tracks a systematic trend in remote sensing data by using a polynomial model. The reconstruction system were applied to the AVHRR data collected over Korean Peninsula. The results show that missing measurements are typically recovered successfully and the temporal trend in vegetation change is exposed clearly in the reconstructed series.

• Korean Journal of Head & Neck Oncology
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• v.34 no.2
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• pp.85-87
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• 2018

The arteriovenous malformation (AVM) is an anomaly of capillary development that results from direct connection between branches of artery and vein without intervening capillary bed. The neurogenic tumors have a tendency to various types of degeneration. Recently, we experienced a 73-year old man with a mass in left supraclavicular area. The intraoperative findings showed severe adhesions with cervical plexus, like a neurogenic tumor. Finally, the mass was revealed as AVM. We report a unique disease pattern with a literature review.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.3
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• pp.451-458
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• 2021

The objective of this research is to analyze the effect of bad credit and liquidity on bank performance with the mediation of capital adequacy. Data were provided by banking institutions listed on the Indonesia Stock Exchange from the period of 2011-2019. The analysis technique was PLS-SEM supported by an application named WarpPLS 6.0. The results of the research show that the effect of bad credit and liquidity on bank performance is not significant. A high level of bad credit is associated with a low level of bank performance. Bank earnings decline along with low profitability. This relationship is not significant because banks can still cover some proportions of bad credit through capital availability. Capital adequacy as an intervening variable has mediated partially the effect of bad credit and liquidity on bank performance. Besides, capital adequacy has a strong effect on credit distribution. Agency theory says that the owner of the fund (the savers of saving account, current account, deposit account) is called principal while the bank as the trusted institution to manage the fund is called an agent. If customers fulfill their duty, then bad credit never happens.

• Journal of Korean Medicine for Obesity Research
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• v.22 no.1
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• pp.77-85
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• 2022

While the Coronavirus disease 2019 (COVID-19) pandemic is gradually turning into an endemic disease, concerns about post COVID-19 conditions (Long COVID) are emerging. Obesity is a major risk factor for severe complications of COVID-19, and COVID-19 has a wide range of effects on obesity and metabolic function. This paper aims to examine the interaction between COVID-19 and obesity, the effects and mechanisms of long COVID on obesity, and the role of Korean medicine on long COVID-related obesity. Obesity may worsen with cardiometabolic damage and psychosocial insecurity during COVID-19 and long COVID-induced neuroinflammation, systemic inflammation, mitochondrial dysfunction, and hypoxia also may aggravate obesity. Korean Medicine treatments, which have been widely used to treat obesity, have the potential to improve obesity in the era of long COVID by intervening in these mechanisms.

• Journal of Animal Reproduction and Biotechnology
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• v.37 no.1
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• pp.62-66
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• 2022

To date, the development of anticancer drugs has been conducted using two-dimensional (2D) cell culture systems. However, since cancer cells in the body are generated and developed in three-dimensional (3D) microenvironments, the use of 2D anticancer drug screening can make it difficult to accurately evaluate the anticancer effects of drug candidates. Therefore, as a step towards developing a cancer cell-friendly 3D microenvironment based on a combination of vinylsulfone-functionalized polyethylene glycol (PEG-VS) with dicysteine-containing crosslinker peptides with an intervening matrix metalloproteinase (MMP)-specific cleavage site, the types of MMPs secreted from human hepatocarcinoma HepG2 cells, a representative cancer cell, were analyzed transcriptionally and translationally. MMP3 was confirmed to be the most highly expressed protease secreted by HepG2 cells. This knowledge will be important in the design of a crosslinker necessary for the construction of PEG-based hydrogels customized for the 3D culture of HepG2 cells.