• Title/Summary/Keyword: interval volume

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Cardiovascular response to surprise stimulus (놀람 자극에 대한 심혈관 반응)

  • Eom, Jin-Sup;Park, Hye-Jun;Noh, Ji-Hye;Sohn, Jin-Hun
    • Science of Emotion and Sensibility
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    • v.14 no.1
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    • pp.147-156
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    • 2011
  • Basic emotions such as happiness, sadness, anger, fear, and disgust have been widely used to investigate emotion-specific autonomic nervous system activity in many studies. On the contrary, surprise emotion, Suggested also as one of the basic emotions suggested by Ekman et al. (1983), has been least investigated. The purpose of this study was to provide a description of cardiovascular responses on surprise stimulus using electrocardiograph (ECG) and photoplethysmograph (PPG). ECG and PPG were recorded from 76 undergraduate students, as they were exposed to a visuo-acoustic surprise stimulus. Heart rate (HR), standard deviation of R-R interval (SD-RR), root mean square of successive R-R interval difference (RMSSD-RR), respiratory sinus arrhythmia (RSA), finger blood volume pulse amplitude (FBVPA), and finger pulse transit time (FPTT) were calculated before and after the stimulus presentation. Results show significant increase in HR, SD-RR, and RMSSD-RR, decreased FBVPA, and shortened FPTT. Evidence suggests that surprise emotion can be characterized by vasoconstriction and accelerated heart rate, sympathetic activation, and increased heart rate variability, parasympathetic activation. These results can be useful in developing an emotion theory, or profiling surprise-specific physiological responses, as well as establishing the basis for emotion recognition system in human-computer interaction.

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Effect of $N_2$-back-flushing in Multi Channels Ceramic Microfiltration System for Paper Wastewater Treatment (제지폐수 처리를 위한 다채널 세라믹 정밀여과 시스템에서 질소 역세척 효과)

  • Park Jin-Yong;Choi Sung-Jin;Park Bo-Reum
    • Membrane Journal
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    • v.16 no.1
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    • pp.31-38
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    • 2006
  • The ceramic microfiltration system with periodic $N_2$-back-flushing was operated for treating paper wastewater discharged from a company making toilet papers by recycling milk or juice cartons. Two kinds of alumina membranes with 7 channels used here for recycling paper wastewater. The optimal filtration time interval for HC04 membrane with $0.4{\mu}m$ pore size was lower value of 4 min than 16 min for HC10 with $1.0{\mu}m$ pore size at fixed back-flushing time 40 sec, trans-membrane pressure $1.0kg_f/cm^2$ and back-flushing pressure $5.0kg_f/cm^2$. From the results of TMP effect at fixed filtration time interval and back-flushing time, the lower TMP was better on membrane fouling because high TMP could make easily membrane cake and fouling inside membrane structure. However, we could acquire the highest volume of total permeate at the highest TMP for the reason that TMP was driving force in our filtration system to treat paper wastewater. Then the permeate water of low turbidity was acquired in our microfiltration system using multi channels ceramic membranes, and the treated water could be reused in paper process.

Tumor Habitat Analysis Using Longitudinal Physiological MRI to Predict Tumor Recurrence After Stereotactic Radiosurgery for Brain Metastasis

  • Da Hyun Lee;Ji Eun Park;NakYoung Kim;Seo Young Park;Young-Hoon Kim;Young Hyun Cho;Jeong Hoon Kim;Ho Sung Kim
    • Korean Journal of Radiology
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    • v.24 no.3
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    • pp.235-246
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    • 2023
  • Objective: It is difficult to predict the treatment response of tissue after stereotactic radiosurgery (SRS) because radiation necrosis (RN) and tumor recurrence can coexist. Our study aimed to predict tumor recurrence, including the recurrence site, after SRS of brain metastasis by performing a longitudinal tumor habitat analysis. Materials and Methods: Two consecutive multiparametric MRI examinations were performed for 83 adults (mean age, 59.0 years; range, 27-82 years; 44 male and 39 female) with 103 SRS-treated brain metastases. Tumor habitats based on contrast-enhanced T1- and T2-weighted images (structural habitats) and those based on the apparent diffusion coefficient (ADC) and cerebral blood volume (CBV) images (physiological habitats) were defined using k-means voxel-wise clustering. The reference standard was based on the pathology or Response Assessment in Neuro-Oncologycriteria for brain metastases (RANO-BM). The association between parameters of single-time or longitudinal tumor habitat and the time to recurrence and the site of recurrence were evaluated using the Cox proportional hazards regression analysis and Dice similarity coefficient, respectively. Results: The mean interval between the two MRI examinations was 99 days. The longitudinal analysis showed that an increase in the hypovascular cellular habitat (low ADC and low CBV) was associated with the risk of recurrence (hazard ratio [HR], 2.68; 95% confidence interval [CI], 1.46-4.91; P = 0.001). During the single-time analysis, a solid low-enhancing habitat (low T2 and low contrast-enhanced T1 signal) was associated with the risk of recurrence (HR, 1.54; 95% CI, 1.01-2.35; P = 0.045). A hypovascular cellular habitat was indicative of the future recurrence site (Dice similarity coefficient = 0.423). Conclusion: After SRS of brain metastases, an increased hypovascular cellular habitat observed using a longitudinal MRI analysis was associated with the risk of recurrence (i.e., treatment resistance) and was indicative of recurrence site. A tumor habitat analysis may help guide future treatments for patients with brain metastases.

Evaluation of the Usefulness of Restricted Respiratory Period at the Time of Radiotherapy for Non-Small Cell Lung Cancer Patient (비소세포성 폐암 환자의 방사선 치료 시 제한 호흡 주기의 유용성 평가)

  • Park, So-Yeon;Ahn, Jong-Ho;Suh, Jung-Min;Kim, Yung-Il;Kim, Jin-Man;Choi, Byung-Ki;Pyo, Hong-Ryul;Song, Ki-Won
    • The Journal of Korean Society for Radiation Therapy
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    • v.24 no.2
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    • pp.123-135
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    • 2012
  • Purpose: It is essential to minimize the movement of tumor due to respiratory movement at the time of respiration controlled radiotherapy of non-small cell lung cancer patient. Accordingly, this Study aims to evaluate the usefulness of restricted respiratory period by comparing and analyzing the treatment plans that apply free and restricted respiration period respectively. Materials and Methods: After having conducted training on 9 non-small cell lung cancer patients (tumor n=10) from April to December 2011 by using 'signal monitored-breathing (guided- breathing)' method for the 'free respiratory period' measured on the basis of the regular respiratory period of the patents and 'restricted respiratory period' that was intentionally reduced, total of 10 CT images for each of the respiration phases were acquired by carrying out 4D CT for treatment planning purpose by using RPM and 4-dimensional computed tomography simulator. Visual gross tumor volume (GTV) and internal target volume (ITV) that each of the observer 1 and observer 2 has set were measured and compared on the CT image of each respiratory interval. Moreover, the amplitude of movement of tumor was measured by measuring the center of mass (COM) at the phase of 0% which is the end-inspiration (EI) and at the phase of 50% which is the end-exhalation (EE). In addition, both observers established treatment plan that applied the 2 respiratory periods, and mean dose to normal lung (MDTNL) was compared and analyzed through dose-volume histogram (DVH). Moreover, normal tissue complication probability (NTCP) of the normal lung volume was compared by using dose-volume histogram analysis program (DVH analyzer v.1) and statistical analysis was performed in order to carry out quantitative evaluation of the measured data. Results: As the result of the analysis of the treatment plan that applied the 'restricted respiratory period' of the observer 1 and observer 2, there was reduction rate of 38.75% in the 3-dimensional direction movement of the tumor in comparison to the 'free respiratory period' in the case of the observer 1, while there reduction rate was 41.10% in the case of the observer 2. The results of measurement and comparison of the volumes, GTV and ITV, there was reduction rate of $14.96{\pm}9.44%$ for observer 1 and $19.86{\pm}10.62%$ for observer 2 in the case of GTV, while there was reduction rate of $8.91{\pm}5.91%$ for observer 1 and $15.52{\pm}9.01%$ for observer 2 in the case of ITV. The results of analysis and comparison of MDTNL and NTCP illustrated the reduction rate of MDTNL $3.98{\pm}5.62%$ for observer 1 and $7.62{\pm}10.29%$ for observer 2 in the case of MDTNL, while there was reduction rate of $21.70{\pm}28.27%$ for observer 1 and $37.83{\pm}49.93%$ for observer 2 in the case of NTCP. In addition, the results of analysis of correlation between the resultant values of the 2 observers, while there was significant difference between the observers for the 'free respiratory period', there was no significantly different reduction rates between the observers for 'restricted respiratory period. Conclusion: It was possible to verify the usefulness and appropriateness of 'restricted respiratory period' at the time of respiration controlled radiotherapy on non-small cell lung cancer patient as the treatment plan that applied 'restricted respiratory period' illustrated relative reduction in the evaluation factors in comparison to the 'free respiratory period.

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Analyses Using Micro-CT Scans and Tissue Staining on New Bone Formation and Bone Fusion According to the Timing of Cranioplasty via Frozen Autologous Bone Flaps in Rabbits : A Preliminary Report

  • Shin, Hee Sup;Lee, Deok-Won;Lee, Seung Hwan;Koh, Jun Seok
    • Journal of Korean Neurosurgical Society
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    • v.57 no.4
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    • pp.242-249
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    • 2015
  • Objective : The timing of cranioplasty and method of bone flap storage are known risk factors of non-union and resorption of bone flaps. In this animal experimental study, we evaluated the efficacy of cranioplasty using frozen autologous bone flap, and examined whether the timing of cranioplasty after craniectomy affects bone fusion and new bone formation. Methods : Total 8 rabbits (male, older than 16 weeks) were divided into two groups of early cranioplasty group (EG, 4 rabbits) and delayed cranioplasty group (DG, 4 rabbits). The rabbits of each group were performed cranioplasty via frozen autologous bone flaps 4 weeks (EG) and 8 weeks (DG) after craniectomy. In order to obtain control data, the cranioplasty immediate after craniectomy were made on the contralateral cranial bone of the rabbits (control group, CG). The bone fusion and new bone formation were evaluated by micro-CT scan and histological examination 8 weeks after cranioplasty on both groups. Results : In the micro-CT scans, the mean values of the volume and the surface of new bone were $50.13{\pm}7.18mm^3$ and $706.23{\pm}77.26mm^2$ in EG, $53.78{\pm}10.86mm^3$ and $726.60{\pm}170.99mm^2$ in DG, and $31.51{\pm}12.84mm^3$ and $436.65{\pm}132.24mm^2$ in CG. In the statistical results, significant differences were shown between EG and CG and between DG and CG (volume : p=0.028 and surface : p=0.008). The histological results confirmed new bone formation in all rabbits. Conclusion : We observed new bone formation on all the frozen autologous bone flaps that was stored within 8 weeks. The timing of cranioplasty may showed no difference of degree of new bone formation. Not only the healing period after cranioplasty but the time interval from craniectomy to cranioplasty could affect the new bone formation.

A Preliminary Evaluation on CO2 Storage Capacity of the Southwestern Part of Ulleung Basin, Offshore, East Sea (동해 울릉분지 남서 주변부의 이산화탄소 저장 용량 예비 평가)

  • Kim, Yu-Lee;Lee, Keum-Suk;Jo, So-Hyun;Kim, Min-Jun;Kim, Jong-Soo;Park, Myong-Ho
    • Economic and Environmental Geology
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    • v.45 no.1
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    • pp.41-48
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    • 2012
  • A theoretical $CO_2$ storage capacity is estimated on the southwestern continental shelf margin of Ulleung Basin, offshore Korea using 2D/3D multi-channel seismic and wellbore data acquired in the area over the two decades since the late 1980s. For the first time in Korea, the present study applies an efficiency factor to the capacity calculation, together with the other required parameters. For possible $CO_2$ storage volume estimation of the study area, we interpreted the seismic data in the Gorae area from 800 m to 3,000 m below the seafloor integrated with the well data, and identified five different seismic units; the limited depth interval is considered because of fluid state of $CO_2$ and tightness of the formation. The total volumes of each seismic unit were converted with a time-depth relation inferred from the checkshot surveys before the other required parameters including porosity and density were applied to compute the potential storage capacity. The accumulated possible storage volume from the five depositional units in the study area is estimated to be approximately 5,100 Mton ($P_{50}$). The approaches made in this study will be applied to the rest area of the basin and other continental shelves (i.e., Yellow Sea and northern part of East China Sea) in the next phase.

Correlation of Marine Exploration-Survey Vessel Operation Factors and Grid-Type Operation Method through ES Model Analysis (환경스트레스 모델을 통한 해양탐사·조사선의 격자형 운항방식과 운항요인 상관관계에 관한 연구)

  • Park, Hyungoo;Park, Young-soo;Kim, Dae-won
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.6
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    • pp.634-643
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    • 2020
  • Because of the continuous increase in the demand for and importance of marine space, marine exploration and survey activities are being actively conducted in Korea actively. Because the marine survey vessels used for these activities have special operational patterns depending on the purpose and probe vessels, research on maritime traffic risk is required. In this study, an attempt was made to determine the correlation of each factor with the effect of marine exploration and survey vessel operation on maritime traffic. The status of ocean exploration and survey vessels in operation in Korea was identified, as well as the special operational conditions of some of the ocean physical probes. Generally, the number of exploration and survey vessels involved per hour, total vessel length(including exploration equipment), operation, interval distance of exploration as per plan, and marine traffic conditions(traffic volume and speed) can be classified as operating factors. To compare the results of the environmental stress, a maritime traffic flow simulation based on the "ES" Model was performed with each of the identified operating factors as independent variables. The results of the analysis confirmed that the environmental stress significantly changed in the order of traffic volume, ship length and speed. In addition, it was confirmed that the environmental stress is reduced when the operation course is set at an angle with the nearby maritime traffic flow. Accordingly, it can help reduce the operator's burden if the survey vessel operator understands nearby maritime traffic conditions and reflects them in the operation method when setting the operation plan.

Study of the Tidal Discharge (조석출입량에 관한 조사)

  • 최귀열
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.10 no.1
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    • pp.1394-1408
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    • 1968
  • The tidal discharge is defined as the quantity of water flowing through a certain cross-section per unit of time, in contrast to river discharges, tidal discharges change periodically in magnitude and direction. Thus the total volumes of water flowing into again out of the system-called flood volume and ebb volume, respectively, depend on both the tidal and the river discharges. To ditermine the tidal discharge and the flood and ebb volumes of the Yong-san river, the discharges were measured at spring, mean and neap tide and simultaneous gage reading were taken at Samhak-do, Lower Myo-do, Myongsan-ni and Naju. The general procedure for measuring the tidal discharges was as follows. First, several cross-sections were measured and one of them was chosen. First, several cross-sections were measured and one of them was chosen. Then verticals were serected in the chosen cross section. Because comparatively few verticals should be representative of the discharge distribution over the river profile, the selection was done in accordance with the somtimes irregular bottom profile. The velocities were measured with the same current meters. The observations which included water level readings were continued for a period of about 13 hours. The current direction meter, a pyramid shaped resistance body, suspend in the water on a thin wire. The bubble in a circular tilting level fixed to the wire indicates the direction of the current. Reading were taken at intervals of 1m for depths of 10m or less, and for depths over 10m at intervals of 2m, going downwards and upwards. The averages of the two velocities were used for the computation of the discharges. The discharges and the flood and ebb volumes were ditermined by a graphical method. The mean velocities, corrected for their direction when necesary, were ditermined for each time interval and each vertical, and these velocities were plotted against the time. The resulting curves show possible mistakes very clearly, and the effect of observation errors could be reduced. The corrected velocities read from the curve at half-hour intervals were multiplied by the depth at the virtical at the corresponding time. The discharges thus found were ploted against the position of the vertical in the transit and joined by a smooth curve, integration of the curve rendered the total discharges as they occurred of half-hour intervals. Plotting these total discharges against the time yeilded during the day. The flood and ebb volumes were obtained by integration of the total discharge curve.

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Factors Related to Exertional Oxygen Desaturation in Patients with COPD (만성 폐쇄성 폐질환(COPD) 환자에서 운동 시 발생하는 산소 불포화 반응과 관련된 인자)

  • Shim, Sang-Woo;Jo, Jun-Yeon;Kwon, Yong-Sik;Chae, Jin-Nyeong;Park, Jie-Hae;Lee, Mi-Young;Rho, Byung-Hak;Choi, Won-Il
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.6
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    • pp.498-503
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    • 2011
  • Background: The causes of exertional desaturation in patients with COPD can be multifactorial. We aimed to investigate factors predict exertional desaturation in patients with moderate to severe COPD. Methods: We tested 51 consecutive patients with stable COPD (FEV1/FVC, $40{\pm}13%$ predicted). Patients performed a six minute walk test (6MWT). Pulse oxymetric saturation (SpO2) and pulse rate were recorded. Results: Oxygen desaturation was found in 15 subjects after 6MWT, while 36 subjects were not desaturated. Lung diffusing capacity was significantly lower in desaturation (DS) group ($62{\pm}18%$ predicted) compared with not desaturated (ND) group ($84{\pm}20$, p<0.01). However there was no statistical difference of FEV1/FVC ratio or residual volume between two groups. The pulse rate change was significantly higher in the desaturated compared with the not desaturated group. Six minute walking distance, subjective dyspnea scale, airflow obstruction, and residual volume did not predict exertional oxygen desaturation. Independent factors assessed by multiple logistic regression revealed that a pulse rate increment (odd ratio [OR], 1.19; 95% confidence interval [CI], 1.01~1.40; p=0.02), a decrease in baseline PaO2 (OR, 1.105; 95% CI, 1.003~1.218; p=0.04) and a decrease in lung diffusing capacity (OR, 1.10; 95% CI, 1.01~1.19; p=0.01) were significantly associated with oxygen desaturation. Receiver operator characteristic (ROC) analysis showed that an absolute increment in pulse rate of 16/min gave optimal discrimination between desaturated and not desaturated patients after 6MWT. Conclusion: Pulse rate increment and diffusion capacity can predict exertional oxygen desaturation in stable COPD patients with moderate to severe airflow obstruction.

A Development of Stem Analysis Program and its Comparison with other Method for Increment Calculation (수간석해(樹幹析解) 전산(電算)프로그램 개발(開發) 및 생장량(生長量) 계산방법(計算方法)의 비교(比較)에 관(關)한 연구(硏究))

  • Byun, Woo Hyuk;Lee, Woo Kyun;Yun, Kwang Bae
    • Journal of Korean Society of Forest Science
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    • v.79 no.1
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    • pp.1-15
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    • 1990
  • In this study the stem analysis program, which can be operated with personal computer was developed to reduce time and cost of calculation, and to increase accuracy of analysis. The stem analysis method used in this program was compared with other methods. The results obtained were as follows : The value, 1/100mm measured from the latest annual ring measurement machine (Jahrringme${\beta}$geraete Johan Type II) was automatically inputed to the computer and saved into given file name. Turbo Pascal program was written to do this. The measured data was analyzed by stem analysis calculation program written by Fortran-77. Volume and height increments were approximated by spline function, and diameter of the stem disk was calculated by quadratic mean method. The increment values calculated by the programs were printed annually and in every five-year. Stem analysis diagram and several increment graphs were also easily printed. The result compared between those analysis methods showed that quadratic mean could reduce the error caused from eccentric pith. When the stem taper curve method, approximated by spline function, was used in the calculation of tree height and volume, increments would be more exactly calculated.

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