• Title/Summary/Keyword: interval probability

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Discriminative validity of the timed up and go test for community ambulation in persons with chronic stroke

  • An, Seung Heon;Park, Dae-Sung;Lim, Ji Young
    • Physical Therapy Rehabilitation Science
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    • v.6 no.4
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    • pp.176-181
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    • 2017
  • Objective: The timed up and go (TUG) test is method used to determine the functional mobility of persons with stroke. Its reliability, validity, reaction rate, fall prediction, and psychological characteristics concerning ambulation ability have been validated. However, the relationship between TUG performance and community ambulation ability is unclear. The purpose of this study was to investigate whether the TUG performance time could indicate community ambulation levels (CAL) differentially in persons with chronic stroke. Design: Cross-sectional study. Methods: Eighty-seven stroke patients had participated in this study. Based on the self-reporting survey results on the difficulties experienced when walking outdoors, the subjects were divided into the independent community ambulation (ICA) group (n=35) and the dependent community ambulation group (n=52). Based on the area under the curve (AUC), the discrimination validity of the TUG performance time was calculated for classifying CAL. The Binomial Logistic Regression Model was utilized to produce the likelihood ratio of selected TUG cut-off values for the distinguishing of community ambulation ability. Results: The selected TUG cut-off values and the area under the curve were <14.87 seconds (AUC=0.871, 95% confidence interval=0.797-0.945), representing a mid-level accuracy. Concerning the likelihood ratio of the selected TUG cut-off value, it was found that the group with TUG performance times shorter than 14.87 seconds showed a 2.889 times higher probability of ICA than those with a TUG score of 14.87 seconds or longer (p<0.05). Conclusions: The TUG can be viewed as an assessment tool that is capable of classifying CAL.

Application of Rasch Analysis to the Korean Version of the Fullerton Advanced Balance Scale (한국어판 플러턴 어드밴스드 균형 척도의 라쉬분석)

  • Kim, Gyoung-mo
    • Physical Therapy Korea
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    • v.23 no.1
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    • pp.46-54
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    • 2016
  • Background: Rasch analysis estimates the probability that a respondent will endorse an item and select a particular rating for that item. It has the advantage of placing both the items and the person along a single ration scale and calibrates person ability and item difficulty onto an interval scale by logits. In addition, Rasch analysis is a useful tool for exploring the validity of questionnaires that have been developed using traditional methods. Therefore, it has been recommended as a method for developing and evaluating functional outcome measures. Objects: The purpose of this study was to investigate the item fit, item difficulty, and rating scale of the Korean version of the Fullerton Advanced Balance Scale (KFAB) using Rasch analysis. Methods: Total 97 subjects (39 males and 58 females) with dwelling elderly adults were participated, but 3 people were excluded for misfit persons. Rasch analysis was then done by means of the Winsteps program to determine the item fit, item difficulty, rating scale, and reliability of the KFAB. Results: In this study, the 'standing with feet together and eyes closed', 'two-footed jump', 'walk with head turns', and 'stand on foam, eyes closed' items shown misfit statistics. The most difficult item was 'stand on one leg', whereas the easiest item was 'turn in full circle'. The rating scale was acceptable with all criteria. Both item and person separation indices and reliability showed acceptable values. This would indicated that each domain covers a useful range of item difficulty that is appropriate for measuring a person with a wide range of functional ability. Conclusion: The KFAB has been proven reliable, valid and an appropriate tool with which to evaluate the balance of the elderly people.

Modifications of DCF Scheme to Alleviate Jitter Property in WLANs (무선 랜의 지터 성능 개선을 위한 DCF 개선 방안)

  • Kang, Dong-Hun;Seok, Seung-Joon
    • Journal of Internet Computing and Services
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    • v.9 no.5
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    • pp.153-163
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    • 2008
  • Almost literature has so far proposed the modifications to IEEE 802.11 DCF MAC protocol to improve system throughput and average delay. Jitter(variance in packet delays) is, however, considered as an important QoS parameter for real-time streaming service which is popularized increasingly. Unfortunately, legacy access protocol for WLAN can't support the jitter. This paper proposes two schemes modifying the DCF MAC protocol to reduce the average value of jitter for multimedia frames arrived at received nodes. The one scheme, referred to as DCW-DCF(Decreasing Contention Window-DCF), reduces CW(Contention Window) size by half whenever a transmitted frame collided against other frames and back-off happens. Also, it increase initial CW size according as the link utilization and the collision probability increase. The other scheme, referred to as D-DIFS(Differential-DIFS), assigns different values to DIFS. That is, the DIFS interval is deceased as the number of back-off for a frame increases. In this paper, the two schemes are evaluated through simulation using ns2 and simulation results show that the proposed schemes are effective for improving the jitter property of standard WLAN.

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Repeated Transsphenoidal Surgery for Pituitary Tumors (경접형골동접근법에 의한 뇌하수체종양의 재수술)

  • Koh, Young-Cho;Yoo, Heon;Kim, Chang-Hyun;Whang, Do-Yun;Jang, Jin-Soon;Park, Hyo-Il
    • Journal of Korean Neurosurgical Society
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    • v.29 no.7
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    • pp.929-934
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    • 2000
  • Objective : The results of secondary transsphenoidal surgery(TSS) for either residual or recurring pituitary adenomas have been reported to be unfavorable. To evaluate the effectiveness of secondary TSS, we analyzed the surgical results of residual or recurred pituitary adenomas in patients who underwent secondary TSS from 1992 to 1998. Material and Methods : Among the 95 patients who underwent TSS during this period, 14(15%) received repeated TSS. Two of the 14 patients underwent three TSS. Among the 11 patients with pituitary adenomas, three had nonfunctioning tumors ; six prolachnomas ; two GH-secreting adenomas. The remaining three patieats had craniopharyngioma, pituitary abscess and hemangioendothelioma respectively. The interval between the two surgical procedures ranged from one week to 33 months(mean ; 12 months). Causes of the secondary TSS were tumor recurrence in 11 patients, intentional staged operation in three, persistent disease despite medical therapy and CSF leak after initial operation in one respectively. Treatments prior to secondary TSS were medical treatment only in eight patients. Results : During the repeated operationtss some adhesion was noted in septal mucous membrane. The sphenoid cavity was filled with fibrous tissue which correlated with the methods of reconstruction of the sellar floor at the previous operation. There was no statistically significant difference in success rate of surgery between the initial and the second TSS(86% vs 81%). The complication rate was similar between the two procedures. There was no statistically significant factors affecting the results of second TSS. Conclusion : Transsphenoidal reoperation was regarded as a suitable approach for treating recurrent pituitary adenomas in spite of some degree of operative difficulties. In patients with transsphenoidally resectable tumor residuals or recurrences confirmed by magnetic resonance imaging, remissions can be obtained with high probability, especially in secondary surgery after an staged decompression.

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An Evaluation of Suckling and Post Weaning Practices in Relation to the Stimulation and Ease of Detection of Oestrus in Nepalese Pakhribas Pigs

  • Shrestha, NP;Edwards, S.A.;English, P.R;Robertson, J.F.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.6
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    • pp.765-770
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    • 2001
  • Thirty second parity sows of the synthetic Nepalese Pakhribas genotype were used to investigate factors which might improve the occurrence and expression of estrus. The experiment had two sequential elements. In part 1, a change in suckling pattern was applied during lactation, and in part 2, different estrus detection methods were evaluated after weaning. All sows received the same pattern of weaning, which imitated the progressive weaning system used in Nepalese villages. Piglets from each litter were weaned at three ages (6, 7 and 8 weeks of age) in the proportion of 0.5 at 6 weeks followed by 0.25 at each of the subsequent weanings. In the first lactation treatment, the suckling pattern was left undisturbed, similar to the practice used in the villages in which the remaining piglets after first weaning are allowed continuous suckling. In the other treatment, the remaining piglets after first weaning were allowed to suckle their sows only during the night, whilst in the day time (09:00-16:00) they were excluded from the sow but left free to roam around. After weaning, estrus detection procedures were carried out in the absence or presence of two different boar stimuli: a synthetic boar pheromone spray or fresh boar urine. These were applied sequentially in a sequence of testing that alternated for each sow on a daily basis. The weaning to re-mating interval was significantly longer for the unrestricted suckling treatment. All sows were re-mated within 30 days after first weaning in the restricted suckling treatment groups, whereas only 71% of sows were re-mated within 30 days after weaning in the unrestricted suckling treatment groups ($x^2=3.877$, 1df, p<0.05). Both boar pheromone spray and boar urine increased the estrus detection probability, with no significant differences between the two stimuli treatments.

Simultaneous Comparison of Efficacy and Adverse Events of Interventions for Patients with Esophageal Cancer: Protocol for a Systematic Review and Bayesian Network Meta-analysis

  • Doosti-Irani, Amin;Mansournia, Mohammad Ali;Rahimi-Foroushani, Abbas;Cheraghi, Zahra;Holakouie-Naieni, Kourosh
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.2
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    • pp.867-872
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    • 2016
  • Background: Esophageal cancer is one of the most serious malignancies. Due to the aggressive nature of this cancer, the prognosis is poor. A network meta-analysis with simultaneous comparison of multiple treatments can help determine better treatment options that have higher effects on overall survival of patients with lower adverse events. The aim of this review is to simultaneously compare efficacy and adverse events of treatment interventions for esophageal cancer. Materials and Methods: In this review, only randomized control trials (RCT) will be considered for network meta-analysis. All international electronic databases including Medline, Web of Sciences, Scopus, Cochran's library, EMBASE and Cancerlit will be searched to find randomized control trials which compared two or more treatment interventions for esophageal cancer. A network plot will be drawn for visual representation of all available treatment interventions. Bayesian approach will be used to combine the direct and indirect evidence. Treatment effects (e.g. hazard ratio for time to event outcomes, risk ratio for binary outcomes, and rate ratio for count outcomes with 95% credible interval) will be reported. Moreover, cumulative probability of the treatment ranks will be reported using the surface under the cumulative ranking (SUCRA) graphs. Consistency assumption will be assessed by the loop-specific and design-by-treatment interaction approaches. Conclusions: The results of this study may be helpful for the patients, clinicians and health policy makers in selecting treatments that have the best effect on survival and lowest adverse events.

External Validation of a Clinical Scoring System for Hematuria

  • Lee, Seung Bae;Kim, Hyung Suk;Kim, Myong;Ku, Ja Hyeon
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6819-6822
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    • 2014
  • Background: The aim of this study was to evaluate the accuracy of a new scoring system in Korean patients with hematuria at high risk of bladder cancer. Materials and Methods: A total of 319 consecutive patients presenting with painless hematuria without a history of bladder cancer were analyzed, from the period of August 2012 to February 2014. All patients underwent clinical examination, and 22 patients with incomplete data were excluded from the final validation data set. The scoring system included four clinical parameters: age (${\geq}50$ = 2 vs. <50 =1), gender (male = 2 vs. female = 1), history of smoking (smoker/ex-smoker = 4 vs. non-smoker = 2) and nature of the hematuria (gross = 6 vs. microscopic = 2). Results: The area under the receiver-operating characteristic curve (95% confidence interval) of the scoring system was 0.718 (0.655-0.777). The calibration plot demonstrated a slight underestimation of bladder cancer probability, but the model had reasonable calibration. Decision curve analysis revealed that the use of model was associated with net benefit gains over the treat-all strategy. The scoring system performed well across a wide range of threshold probabilities (15%-45%). Conclusions: The scoring system developed is a highly accurate predictive tool for patients with hematuria. Although further improvements are needed, utilization of this system may assist primary care physicians and other healthcare practitioners in determining a patient's risk of bladder cancer.

Severity-Adjusted Mortality Rates of Coronary Artery Bypass Graft Surgery Using MedisGroups (MedisGroups를 이용한 관상동맥우회술의 중증도 보정사망률에 관한 연구)

  • Kwon, Young-Dae
    • Quality Improvement in Health Care
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    • v.7 no.2
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    • pp.218-228
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    • 2000
  • Background : Among 'structure', 'process' and 'outcome' approaches, outcome evaluation is considered as the most direct and best approach to assess the quality of health care providers. Risk-adjustment is an essential method to compare outcome across providers. This study has aims to judge performance of hospitals by severity adjusted mortality rates of coronary artery bypass graft (CABG) surgery. Methods : Medical records of 584 patients who got the CABG surgery in 6 general hospitals during 1996 and 1997 were reviewed by trained nurses. The MedisGroups was used to quantify severity of patients. The predictive probability of death was calculated for each patient in the sample from a multivariate logistic regression model including the severity score, age and sex. For evaluation of hospital performance, we calculated ratio of observed number to expected number of deaths and z score [(observed number of deaths - expected number of deaths)/square root of the variance in the number of deaths], and compared observed mortality rate with confidence interval of adjusted mortality rate for each hospital. Results : The overall in-hospital mortality was 7.0%, ranged from 2.7% to 15.7% by hospital. After severity adjustment the mortality by hospital was from 2.7% to 10.7%. One hospital with poor performance was distinctly divided from others with good performance. Conclusion : In conclusion, severity-adjusted mortality rate of CABG surgery might be applied as an indicator for hospital performance evaluation in Korea. But more pilot studies and improvement of methodologies has to be done to use it as quality indicator.

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On Confidence Intervals of Robust Regression Estimators (로버스트 회귀추정에 의한 신뢰구간 구축)

  • Lee Dong-Hee;Park You-Sung;Kim Kee-Whan
    • The Korean Journal of Applied Statistics
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    • v.19 no.1
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    • pp.97-110
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    • 2006
  • Since it is well-established that even high quality data tend to contain outliers, one would expect fat? greater reliance on robust regression techniques than is actually observed. But most of all robust regression estimators suffers from the computational difficulties and the lower efficiency than the least squares under the normal error model. The weighted self-tuning estimator (WSTE) recently suggested by Lee (2004) has no more computational difficulty and it has the asymptotic normality and the high break-down point simultaneously. Although it has better properties than the other robust estimators, WSTE does not have full efficiency under the normal error model through the weighted least squares which is widely used. This paper introduces a new approach as called the reweighted WSTE (RWSTE), whose scale estimator is adaptively estimated by the self-tuning constant. A Monte Carlo study shows that new approach has better behavior than the general weighted least squares method under the normal model and the large data.

Determination of Resetting Time to the Process Mean Shift with Failure (고장을 고려한 공정평균 이동에 대한 조정시기 결정)

  • Lee, Do-Kyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.42 no.4
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    • pp.145-152
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    • 2019
  • All machines deteriorate in performance over time. The phenomenon that causes such performance degradation is called deterioration. Due to the deterioration, the process mean of the machine shifts, process variance increases due to the expansion of separate interval, and the failure rate of the machine increases. The maintenance model is a matter of determining the timing of preventive maintenance that minimizes the total cost per wear between the relation to the increasing production cost and the decreasing maintenance cost. The essential requirement of this model is that the preventive maintenance cost is less than the failure maintenance cost. In the process mean shift model, determining the resetting timing due to increasing production costs is the same as the maintenance model. In determining the timing of machine adjustments, there are two differences between the models. First, the process mean shift model excludes failure from the model. This model is limited to the period during the operation of the machine. Second, in the maintenance model, the production cost is set as a general function of the operating time. But in the process mean shift model, the production cost is set as a probability functions associated with the product. In the production system, the maintenance cost of the equipment and the production cost due to the non-confirming items and the quality loss cost are always occurring simultaneously. So it is reasonable that the failure and process mean shift should be dealt with at the same time in determining the maintenance time. This study proposes a model that integrates both of them. In order to reflect the actual production system more accurately, this integrated model includes the items of process variance function and the loss function according to wear level.