• 근관절건강학회지
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• 제21권3호
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• pp.173-183
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• 2014

Purpose: This study examined the effects of exercise programs on the pain and quality of life in patients with knee osteoarthritis. Methods: Electronic bibliographic databases of KiSTi, KoreaMed, KISS and KERIS were searched to identify studies of randomized controlled trials and non-randomized controlled trials. As a result, 1213 publications identified and 16 studies met inclusion and exclusion criteria. All studies examined for quality assessment of studies using Cochrane's risk of bias. Results: The 16 studies were eligible for inclusion criteria, then the meta-analysis was conducted to examine effectiveness of exercise programs on pain and quality of life in patients with knee osteoarthritis. The meta- analysis based on the random effect model showed that the exercise program was beneficial in decreasing pain (effect size .69; 95% confidence interval 0.45~0.91). Also, the exercise programs have been shown to be effective in significantly improving the quality of life. However, it was not statistically significant due to severe deviations of studies (effect size 1.06; 95% confidence interval -0.34~2.46). Conclusion: Exercise programs had positive effects on pain relief and improvement of the quality of life in patients with knee osteoarthritis, although the quality of life was not statistically significant due to severe deviations of studies.

• 산업경영시스템학회지
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• 제41권1호
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• pp.50-58
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• 2018

Intermittent demand is a demand with a pattern in which zero demands occur frequently and non-zero demands occur sporadically. This type of demand mainly appears in spare parts with very low demand. Croston's method, which is an initiative intermittent demand forecasting method, estimates the average demand by separately estimating the size of non-zero demands and the interval between non-zero demands. Such smoothing type of forecasting methods can be suitable for mid-term or long-term demand forecasting because those provides the same demand forecasts during the forecasting horizon. However, the smoothing type of forecasting methods aims at short-term forecasting, so the estimated average forecast is a factor to decrease accuracy. In this paper, we propose a forecasting method to improve short-term accuracy by improving Croston's method for intermittent demand forecasting. The proposed forecasting method estimates both the non-zero demand size and the zero demands' interval separately, as in Croston's method, but the forecast at a future period adjusted by binomial weight according to occurrence probability. This serves to improve the accuracy of short-term forecasts. In this paper, we first prove the unbiasedness of the proposed method as an important attribute in forecasting. The performance of the proposed method is compared with those of five existing forecasting methods via eight evaluation criteria. The simulation results show that the proposed forecasting method is superior to other methods in terms of all evaluation criteria in short-term forecasting regardless of average size and dispersion parameter of demands. However, the larger the average demand size and dispersion are, that is, the closer to continuous demand, the less the performance gap with other forecasting methods.

• Radiation Oncology Journal
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• 제36권2호
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• pp.114-121
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• 2018

Purpose: To explore the feasibility of maximum diameter as a response assessment method for vestibular schwannomas (VS) after stereotactic radiosurgery or fractionated stereotactic radiotherapy (RT), we analyzed the concordance of RT responses between maximum diameters and volumetric measurements. Materials and Methods: Forty-two patients receiving curative stereotactic radiosurgery or fractionated stereotactic RT for VS were analyzed retrospectively. Twelve patients were excluded: 4 did not receive follow-up magnetic resonance imaging (MRI) scans and 8 had initial MRI scans with a slice thickness >3 mm. The maximum diameter, tumor volume (TV), and enhanced tumor volume (ETV) were measured in each MRI study. The percent change after RT was evaluated according to the measurement methods and their concordances were calculated with the Pearson correlation. The response classifications were determined by the assessment modalities, and their agreement was analyzed with Cohen kappa statistics. Results: Median follow-up was 31.0 months (range, 3.5 to 86.5 months), and 90 follow-up MRI studies were analyzed. The percent change of maximum diameter correlated strongly with TV and ETV (r(p) = 0.85, 0.63, p = 0.000, respectively). Concordance of responses between the Response Evaluation Criteria in Solid Tumors (RECIST) using the maximum diameters and either TV or ETV were moderate (kappa = 0.58; 95% confidence interval, 0.32-0.85) or fair (kappa = 0.32; 95% confidence interval, 0.05-0.59), respectively. Conclusions: The percent changes in maximum diameter and the responses in RECIST were significantly concordant with those in the volumetric measurements. Therefore, the maximum diameters can be used for the response evaluation of VS following stereotactic RT.

• 디지털융복합연구
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• 제16권7호
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• pp.249-257
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• 2018

본 논문은 신기술이 융합된 도로안전시설물에 대한 평가기준 탐색 및 평가를 위한 가상현실 시뮬레이션 환경 구축을 목적으로 하였다. 가상현실 시뮬레이션을 위해서는 높은 현실감과 정확한 행동 데이터 추출이 필요하다. 이를 위해 Unreal Engine을 활용하여 주변 환경을 외부환경과 차량환경으로 나눠 제작하였다. 외부환경은 주변 환경, 날씨, 시간대, 타 차량으로 나눠 제작하였으며 차량환경은 승용차와 화물차를 요인으로 제작하였다. 이후, 발광 도로표지병에 대한 샘플 시뮬레이션 제작 및 사전실험을 진행하여, 도로표지병이 5m 간격이 10m 간격보다 더 차선유도를 잘한다는 결과를 나타냈다. 이는 차후 새로운 기술이 접목된 새로운 도로안전시설물에 대한 평가기준에 대한 탐색을 위한 시뮬레이션 작성에서도 활용 가능하다는 것을 확인할 수 있었다. 향후, 다른 도로시설물에 대한 모델링 및 샘플 컴포넌트를 추가하여 다양한 환경에 대한 시뮬레이션이 가능하도록 할 수 있을 것이다.

• 문화기술의 융합
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• 제8권3호
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• pp.551-557
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• 2022

대심도 지하 터널 공사에서 마주치는 지반공학적 위험인자는 다양하며, 심도와 한국의 지역적 지질특성에 따라 위험인자의 종류와 기준이 다르다. 도심 지하 복합 지반의 다양한 다공질의 특성을 보이는 지질의 특성 및 지질구조가 안전성에 미치는 영향을 이해하기위해 국내외 사례를 바탕으로 한국의 대심도 암반의 위험 인자를 분석하였다. 연구 결과 대심도 터널지반의 안정성에 영향을 주는 7개의 카테고리들 즉, 지질구조, 암반특성, 수리지질, Overburden, 높은 응력, 지반특성 및 인공 구조물과 약 20 여개의 위험인자들이 도출 되었다. 위험인자들 중 가장 영향력이 큰 단층, 습곡, 암맥 및 암석 종류에 따른 위험기준 및 위험산정을 위한 구간 값을 제시한다. 다른 인자들의 기준과 구간 값은 연구 중에 있다.

• Journal of Trauma and Injury
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• 제29권4호
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• pp.139-145
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• 2016

Purpose: The major pelvic trauma results in high mortality with associated fatal other injuries. During early stage of resuscitation, multidisciplinary approach is essential to improve the survival and outcomes. This study aims to report the effect and positive outcome of the trauma team approach on the management of hemodynamically unstable pelvic bone fracture. Methods: This retrospective review included all patients with hemodynamically unstable pelvic bone fracture admitted between March 2007 and December 2015. Patients were divided into group A, which comprised those admitted before the trauma team approach was started, and group B, which comprised those admitted after the approach was started. The advanced trauma life support protocol was followed for all patient. The comparisons between the two groups were based on medical records. Study variables included demographics, initial vital sign, injury severity score, fracture type, and injury mechanism. We analyzed the outcomes in each group with respect to the time interval for doctors' arrival, total length of stay in the emergency department (ED), time interval for computed tomography evaluation, 24-hour mortality, time interval for definitive fixation, and definitive fixation in the time-window of opportunity. Results: Fifty-three patients met the inclusion criteria. No statistically significant differences in demographic data existed between the two groups. The time interval for doctors' arrival (min, $63.09{\pm}50.48$ vs $21.48{\pm}17.75$; p=0.038) and total length of stay in the ED (min, $269.33{\pm}105.96$ vs $115.49{\pm}56.24$; p=0.023) were significantly improved. The 24-hour mortality was not significantly different between the two groups.(%, 14.3 vs 12.0; p=1.000) However, the time interval for definitive fixation and definitive fixation in the time-window of opportunity showed better results. Conclusion: The trauma team approach has positive effects, which include initial resuscitation through multidisciplinary approach and shortening the time interval to definitive fixation, on the management of hemodynamically unstable pelvic bone fracture.

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1123-1127
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• 2016

Chemotherapy is the primary treatment for advanced and recurrent cervical cancer. To evaluate the survival outcomes of chemotherapy and the prognostic factors in this setting, we conducted a retrospective study by reviewing the medical records of advanced and recurrent cervical cancer patients treated with systemic chemotherapy at our institute between January, 2008 and December, 2014. One hundred and seventy-three patients met the criteria with a mean age of 50.9 years. 4.1% of them were HIV positive. The most common initial stage was stage IVB (30.1%) and the most common histology was squamous cell carcinoma (68.6%). Ninety-two (53.2%) patients were previously treated with concurrent chemoradiation with 53% developing combined sites of recurrence. The median recurrence free interval was 16.7 months. Cisplatin + 5 fluorouracil (5FU) (53.2%) was the most frequent first line chemotherapy followed by carboplatin + paclitaxel (20.2%) with an objective response of 39.3%. Seventy-two patients received subsequent chemotherapy. The median overall survival of all studied patients was 13.2 months. Only a recurrence free interval of less than 12 months was an independent prognostic factor for survival outcome. In conclusion, chemotherapy treatment for advanced and recurrent cervical cancer patients showed modest efficacy with a shorter recurrence free survival less than 12 months as a significant poor prognosis factor.

• 한국의류학회지
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• 제44권2호
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• pp.310-320
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• 2020

This study established a lower garment sizing system for abdominal obesity adult women aged 30-59 based on 277 females selected from the 7th Size Korean Anthropometric survey. The criteria for subjects in this study were over 25 kg/㎡ of the BMI, over 85 cm of waist, and over 0.8 waist hip ratio. The results are as follows. The lower body analysis of abdominal obesity adult women showed that average circumference items were larger than the ordinary size, and the average length items were smaller. The standard deviation was applied around the average values of waist circumference and hip circumference for the suggestion of a lower garment sizing system for abdominal obesity adult women. The interval between the designation was ±1.5 cm with a waist circumference of 100 cm and ±2.5 cm with an average hip circumference of 100 cm. We established 13 designation sections in consideration of the cover ratio and cover efficiency. The cover ratio in the 13 nominal sections was 71.5%. The segmental distribution rate presented in the results will also be useful for production planning in specific sizes that helped enable rational production.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2003년도 제8차 학술대회 초록집
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• pp.37-37
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• 2003

To assess the merits and demerits of postcontrast fat-suppressed (FS) brain MR imaging in children in the evaluation of various enhancing lesions, compared with postcontrast conventional or Magnetization Transfer (MT) imaging. 대상 및 방법： We reviewed patients with enhancing lesion on brain MR imaging who underwent both FS imaging and one of conventional or MT imaging as a postcontrast T1-weighted brain MR imaging. Inclusion criteria of our study were as follows： MR studies should be peformed within one-year interval and showed no significant interval change of imaging findings. Thirty-four patients (21 male, 13 female; mean age, 8 years) with 43 enhancing lesions (19 intra-axial, 19 extra-axial, and 5 orbital location) were included in this study, Twenty-one pairs of FS and conventional imaging, and 15 pairs of FS and MT imaging were available. Two radiologists visually assessed the lesion conspicuity and the presence of flow or susceptibility artifacts in a total of 36 pairs of MR imaging by consensus. For 21 measurable lesions (19 pairs of FS and conventional imaging, 5 pairs of FS and MR imaging), contrast ratio between the lesion and the normal brain( ［SIlesion-SIwater］/[SInormal brain-SIwater]) were calculated and compared.

• 한국물환경학회지
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• 제29권1호
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• pp.55-65
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• 2013

It is very difficult to apply stream flow data directly to the management of Total Maximum Daily Loads because there are some differences between the unit watershed and the stream flow monitoring network in their characteristics such as monitoring locations and its intervals. Flow duration curve can be developed by linking the daily flow data of stream monitoring network to 8 day interval flow data of the unit watershed. This study investigated the current operating conditions of the stream flow monitoring network and the flow relationships between the unit watershed and the stream flow monitoring network. Criteria such as missing and zero value data, and correlation coefficients were applied to select the stream flow reference sites. The reference sites were selected in 112 areas out of 142 unit watersheds in 4 river basins, where the stream flow observations were carried out in relatively normal operating conditions. These reference sites could be utilized in various ways such as flow variation analysis, flow duration curve development and so on for the management of Total Maximum Daily Loads.