• Title/Summary/Keyword: interval censored

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Empirical Bayesian Prediction Analysis on Accelerated Lifetime Data (가속수명자료를 이용한 경험적 베이즈 예측분석)

  • Cho, Geon-Ho
    • Journal of the Korean Data and Information Science Society
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    • v.8 no.1
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    • pp.21-30
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    • 1997
  • In accelerated life tests, the failure time of an item is observed under a high stress level, and based on the time the performances of items are investigated at the normal stress level. In this paper, when the mean of the prior of a failure rate is known in the exponential lifetime distribution with censored accelerated failure time data, we utilize the empirical Bayesian method by using the moment estimators in order to estimate the parameters of the prior distribution and obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

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Nonparametric Inference for the Recurrent Event Data with Incomplete Observation Gaps

  • Kim, Jin-Heum;Nam, Chung-Mo;Kim, Yang-Jin
    • The Korean Journal of Applied Statistics
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    • v.25 no.4
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    • pp.621-632
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    • 2012
  • Recurrent event data can be easily found in longitudinal studies such as clinical trials, reliability fields, and the social sciences; however, there are a few observations that disappear temporarily in sight during the follow-up and then suddenly reappear without notice like the Young Traffic Offenders Program(YTOP) data collected by Farmer et al. (2000). In this article we focused on inference for a cumulative mean function of the recurrent event data with these incomplete observation gaps. Defining a corresponding risk set would be easily accomplished if we know the exact intervals where the observation gaps occur. However, when they are incomplete (if their starting times are known but their terminating times are unknown) we need to estimate a distribution function for the terminating times of the observation gaps. To accomplish this, we treated them as interval-censored and then estimated their distribution using the EM algorithm proposed by Turnbull (1976). We proposed a nonparametric estimator for the cumulative mean function and also a nonparametric test to compare the cumulative mean functions of two groups. Through simulation we investigated the finite-sample performance of the proposed estimator and proposed test. Finally, we applied the proposed methods to YTOP data.

Estimation of a Product Replacement Ratio During the Warranty Period for a Warranty Analysis (보증분석을 위한 품질보증 기간 중 제품 교체율 추정 사례 연구)

  • Ahn, Hae-Il
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.35 no.2
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    • pp.71-79
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    • 2012
  • In this paper, an evaluation of a product replacement ratio of irreparable items to the normally working ones is performed with a view to a warranty analysis. It is demonstrated that the replacement ratio during the warranty period can be estimated from the field data collected during the period of operation, and one can provide the management with a useful information regarding the appropriateness for the warranty period, which is vital to the product marketing strategy. Although warranty data usually take the form of multiply right censored interval data, the conventional reliability analysis method seems to be good enough as in this case. More sophisticated method such as warranty cost analysis and 2-dimensional warranty analysis is yet desired.

Statistical Analysis of Bivariate Recurrent Event Data with Incomplete Observation Gaps

  • Kim, Yang-Jin
    • Communications for Statistical Applications and Methods
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    • v.20 no.4
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    • pp.283-290
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    • 2013
  • Subjects can experience two types of recurrent events in a longitudinal study. In addition, there may exist intermittent dropouts that results in repeated observation gaps during which no recurrent events are observed. Therefore, theses periods are regarded as non-risk status. In this paper, we consider a special case where information on the observation gap is incomplete, that is, the termination time of observation gap is not available while the starting time is known. For a statistical inference, incomplete termination time is incorporated in terms of interval-censored data and estimated with two approaches. A shared frailty effect is also employed for the association between two recurrent events. An EM algorithm is applied to recover unknown termination times as well as frailty effect. We apply the suggested method to young drivers' convictions data with several suspensions.

Developing statistical models and constructing clinical systems for analyzing semi-competing risks data produced from medicine, public heath, and epidemiology (의료, 보건, 역학 분야에서 생산되는 준경쟁적 위험자료를 분석하기 위한 통계적 모형의 개발과 임상분석시스템 구축을 위한 연구)

  • Kim, Jinheum
    • The Korean Journal of Applied Statistics
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    • v.33 no.4
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    • pp.379-393
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    • 2020
  • A terminal event such as death may censor an intermediate event such as relapse, but not vice versa in semi-competing risks data, which is often seen in medicine, public health, and epidemiology. We propose a Weibull regression model with a normal frailty to analyze semi-competing risks data when all three transition times of the illness-death model are possibly interval-censored. We construct the conditional likelihood separately depending on the types of subjects: still alive with or without the intermediate event, dead with or without the intermediate event, and dead with the intermediate event missing. Optimal parameter estimates are obtained from the iterative quasi-Newton algorithm after the marginalization of the full likelihood using the adaptive importance sampling. We illustrate the proposed method with extensive simulation studies and PAQUID (Personnes Agées Quid) data.

A Study of the Small Sample Warranty Data Analysis Using the Bayesian Approach (베이지안 기법을 이용한 소표본 보증데이터 분석 방법 연구)

  • Kim, Jong-Gurl;Sung, Ki-Woo;Song, Jung-Moo
    • Proceedings of the Safety Management and Science Conference
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    • 2013.04a
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    • pp.517-531
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    • 2013
  • 보증 데이터를 통해 제품의 수명 및 형상모수를 추정할 때 최우추정법과 같은 전통적인 통계 분석방법(Classical Statistical Method)을 많이 사용하였다. 그러나 전통적인 통계 분석방법을 통해 수명과 형상모수의 추정 시 표본의 크기가 작거나 불완전한 경우 추정량의 신뢰성이 떨어진다는 단점이 있고 또 누적된 경험과 과거자료를 충분히 이용하지 못하는 단점도 있다. 이러한 문제점을 해결하기 위해 모수의 사전분포를 가정하는 베이지안(Bayesian) 기법의 적용이 필요하다. 하지만 보증 데이터분석에 있어서 베이지안 기법을 이용한 연구는 아직 미흡한 실정이다. 본 연구에서는 수명분포가 와이블 분포를 갖는 보증데이터를 활용하여 모수 추정의 효율성을 비교 분석하고자 한다. 이를 위해 와이블 분포의 모수가 대수정규분포를 따르는 사전분포를 갖는 베이지안 기법과 전통적 통계기법인 생명표법(Actuarial method)을 활용하여 추정량을 도출하고 비교 분석하였다. 이를 통해 충분한 관측 데이터를 확보할 수 없는 경우에 베이지안 기법을 이용한 보증 데이터 분석방법의 성능을 확인하고자 한다.

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Economic Valuation of Yeido Park: Application of Double-Bounded Dichotomous Choice Contingent Valuation Method (여의도공원의 경제적 가치평가: 二段階 二選 假想價値推定法을 적용하여)

    • Journal of the Korean Institute of Landscape Architecture
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    • v.26 no.3
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    • pp.90-103
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    • 1998
  • The purposes of this study are to estimate the economic value and reasonable entrance fee of the Yeido Park, which is under construction in Seoul, by conduct the face-to-face interview. A total of 645 daults were selected by two stage cluster sampling. The senario was designed to meet the requirements for doubgle-bounded dichotomous choice CVM, and distributed with the photograph to epict and compare the current and suggested conditions. A donation vehicle and entrance fee were utilized to find the possibility of strategic behaviors and protest zero, and to make the data estimatable tfor interval censored survival analysis. Date was calibrated by the survival analysis to eleminate the 'fat-tail problem'. Weibull distribution was assumed as a baseline distrubution. The mean WTP of donation and entrance fee was ₩5,281 and ₩783, respectively. The economic value of this park was determined by aggregating the mean value, giving a total WTP for the population of ₩36,861,645,000. This economic value was composed with the use value and existence value. The calibrationi of the Weibull proportional hazard model showed that nearness to the park, age, intention to isit the park, and educational attainment were significant independent variable to influence an amount of donation.

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Sample Size Determination in survival Studies (생존함수의 비교연구를 위한 표본수의 결정)

  • 박미라;김선우;이재원
    • The Korean Journal of Applied Statistics
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    • v.11 no.2
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    • pp.269-285
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    • 1998
  • One of the most important issues in the area of clinical trial research is the determination of the sample size required to insure a specified power in detecting a real or clinically relevant difference of a stated magnitude. Increasingly, medical journals are requiring authors to provide information on the sample size needed to detect a given difference. We restrict our attention to the designs far comparirng two survival distributions. These are concerned with the survival time which is defined as the interval from a baseline(e.g. randomization) to failure (e.g. death, recurrence of disease). Survival times axe right censored when patients have not foiled by the time of analysis or have been loss to follow-up during the trial. For different types of clinical trials for comparing survival distributions, there have been marry research in sample size determination. We review the existing literature concerning commonly used sample size formulae in the design of randomized clinical trials, and compare the assumption, the power and the sample size calculation of these methods. We also compare by simulation the expected power and observed power of each method under various circumstances. As a result, guidelines in terms of practical usage are provided.

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Survival Analysis of Gastric Cancer Patients with Incomplete Data

  • Moghimbeigi, Abbas;Tapak, Lily;Roshanaei, Ghodaratolla;Mahjub, Hossein
    • Journal of Gastric Cancer
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    • v.14 no.4
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    • pp.259-265
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    • 2014
  • Purpose: Survival analysis of gastric cancer patients requires knowledge about factors that affect survival time. This paper attempted to analyze the survival of patients with incomplete registered data by using imputation methods. Materials and Methods: Three missing data imputation methods, including regression, expectation maximization algorithm, and multiple imputation (MI) using Monte Carlo Markov Chain methods, were applied to the data of cancer patients referred to the cancer institute at Imam Khomeini Hospital in Tehran in 2003 to 2008. The data included demographic variables, survival times, and censored variable of 471 patients with gastric cancer. After using imputation methods to account for missing covariate data, the data were analyzed using a Cox regression model and the results were compared. Results: The mean patient survival time after diagnosis was $49.1{\pm}4.4$ months. In the complete case analysis, which used information from 100 of the 471 patients, very wide and uninformative confidence intervals were obtained for the chemotherapy and surgery hazard ratios (HRs). However, after imputation, the maximum confidence interval widths for the chemotherapy and surgery HRs were 8.470 and 0.806, respectively. The minimum width corresponded with MI. Furthermore, the minimum Bayesian and Akaike information criteria values correlated with MI (-821.236 and -827.866, respectively). Conclusions: Missing value imputation increased the estimate precision and accuracy. In addition, MI yielded better results when compared with the expectation maximization algorithm and regression simple imputation methods.

Estimation of the survival function of the legislative process in Korea: based on the experiences of the 17th, 18th, and 19th National Assembly of Korea (국회 법안 검토 기간의 생존함수 추정: 제 17, 18, 19대 국회의 사례를 바탕으로)

  • Yun, Yeonggyu;Cho, Yunsoo;Jung, Hye-Young
    • The Korean Journal of Applied Statistics
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    • v.32 no.4
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    • pp.503-515
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    • 2019
  • In this study we estimate the survival function of duration of the legislative processes in the 17th, 18th, and 19th National Assembly of Korea, and further analyze effects of the political situation variables on the legislative process. We define the termination of legislative process from a novel perspective to alleviate issues of dependency between censoring and failure in the data. We also show that the proportional hazards assumption does not hold for the data, and analyze data employing a log-normal accelerated failure time model. The policy areas of law agendas are shown to affect the speed of legislative process in different ways and legislative process tends to be prompt in times of divided governments.