• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.1
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• pp.50-63
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• 2023

Objectives : This study used a network pharmacology approach to explore the active compounds and therapeutic mechanisms of Yijin-tang on Meniere's disease. Methods : The active compounds of Yijin-tang were screened via the TCMSP database and their target proteins were screened via the STITCH database. The GeneCard was used to establish the Meniere's disease-related genes. The intersection targets were obtained through Venny 2.1.0. The related protein interaction network was constructed with the STRING database, and topology analysis was performed through CytoNCA. GO biological function analysis and KEGG enrichment analysis for core targets were performed through the ClueGO. Results : Network analysis identified 126 compounds in five herbal medicines of Yijin-tang. Among them, 15 compounds(naringenin, beta-sitosterol, stigmasterol, baicalein, baicalin, calycosin, dihydrocapsaicin, formononetin, glabridin, isorhamnetin, kaempferol, mairin, quercetin, sitosterol, nobiletin) were the key chemicals. The target proteins were 119, and 7 proteins(TNF, CASP9, PARP1, CCL2, CFTR, NOS2, NOS1) were linked to Meniere's disease-related genes. Core genes in this network were TNF, CASP9, and NOS2. GO/KEGG pathway analysis results indicate that these targets are primarily involved in regulating biological processes, such as excitotoxicity, oxidative stress, and apoptosis. Conclusion : Pharmacological network analysis can help to explain the applicability of Yijin-tang on Meniere's disease.

• Smart Structures and Systems
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• v.29 no.1
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• pp.237-250
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• 2022

Structural health monitoring (SHM) plays an important role in ensuring the safety and functionality of critical civil infrastructure. In recent years, numerous researchers have conducted studies to develop computer vision and machine learning techniques for SHM purposes, offering the potential to reduce the laborious nature and improve the effectiveness of field inspections. However, high-quality vision data from various types of damaged structures is relatively difficult to obtain, because of the rare occurrence of damaged structures. The lack of data is particularly acute for fatigue crack in steel bridge girder. As a result, the lack of data for training purposes is one of the main issues that hinders wider application of these powerful techniques for SHM. To address this problem, the use of synthetic data is proposed in this article to augment real-world datasets used for training neural networks that can identify fatigue cracks in steel structures. First, random textures representing the surface of steel structures with fatigue cracks are created and mapped onto a 3D graphics model. Subsequently, this model is used to generate synthetic images for various lighting conditions and camera angles. A fully convolutional network is then trained for two cases: (1) using only real-word data, and (2) using both synthetic and real-word data. By employing synthetic data augmentation in the training process, the crack identification performance of the neural network for the test dataset is seen to improve from 35% to 40% and 49% to 62% for intersection over union (IoU) and precision, respectively, demonstrating the efficacy of the proposed approach.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.4
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• pp.571-576
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• 2022

Due to the epochal development of the unmanned technology, the importance of LDT(: Location Detection Technology), which accurately estimates the location of a user or object, is dramatically increased. TOA(: Time of Arrival), which calculates a location by measuring the arrival time of signals, and TDOA(: Time Difference of Arrival) which calculates it by measuring the difference between two arrival times, are representative LDT methods. Based on the signals received from three or more base stations, TOA calculates an intersection point by drawing circles and TDOA calculates it by drawing hyperbolas. In order to improve the radio shadow area problem, a huge number of repeaters have been installed in the urban area, but the signals received through these repeaters may cause the serious error for estimating a location. In this paper, we propose an efficient location estimation technique using the signal received through the repeater. The proposed approach estimates the location of MS(: Mobile Station) employing TOA and TDOA methods, based on signals received from one repeater and two BS(: Base Station)s.

• Imaging Science in Dentistry
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• v.52 no.4
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• pp.351-357
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• 2022

Purpose: Convolutional neural networks (CNNs) have rapidly emerged as one of the most promising artificial intelligence methods in the field of medical and dental research. CNNs can provide an effective diagnostic methodology allowing for the detection of early-staged diseases. Therefore, this study aimed to evaluate the performance of a deep CNN algorithm for apical lesion segmentation from panoramic radiographs. Materials and Methods: A total of 1000 panoramic images showing apical lesions were separated into training (n=800, 80%), validation (n=100, 10%), and test (n=100, 10%) datasets. The performance of identifying apical lesions was evaluated by calculating the precision, recall, and F1-score. Results: In the test group of 180 apical lesions, 147 lesions were segmented from panoramic radiographs with an intersection over union (IoU) threshold of 0.3. The F1-score values, as a measure of performance, were 0.828, 0.815, and 0.742, respectively, with IoU thresholds of 0.3, 0.4, and 0.5. Conclusion: This study showed the potential utility of a deep learning-guided approach for the segmentation of apical lesions. The deep CNN algorithm using U-Net demonstrated considerably high performance in detecting apical lesions.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.2
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• pp.1-9
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• 2023

Objectives : This study used a network pharmacology approach to analyze the treatment mechanisms of Yijin-tang on Meniere's disease, and comparative analysis the treatment mechanisms of drugs recommended in the Meniere's disease treatment guidelines. Methods : We collected information on the recommended drugs from the Meniere's disease treatment guidelines and their target proteins were screened via the STITCH database. The intersection targets were obtained through Venny 2.1.0. Gene Ontology(GO) analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway analysis were performed using ClueGO. Results : The 7 proteins(TNF, CASP9, PARP1, CCL2, CFTR, NOS2, NOS1) were associated with both Yijin-tang and Meniere's disease related genes. The 10 proteins(AQP2, KCNE1, AQP1, AVP, ACE, HRH1, HRH3, NOS1, CA1, CFTR) were associated with both the recommended drugs in the guidelines and Meniere's disease related genes. The 2 proteins(CFTR, NOS1) were common across all three groups. Further, GO/KEGG pathway analysis of the collected proteins revealed that the common mechanisms of action between Yijin-tang and the recommended drugs in the guidelines were related to pathways involving immune dysfunction and disturbances in lymphatic fluid homeostasis. In addition, the recommended drugs in the guidelines appeared to act through mechanisms that improve blood flow through vasodilation. Conclusions : Pharmacological network analysis can help to explain the treatment mechanisms of Yijin-tang on Meniere's disease.

• Journal of the Economic Geographical Society of Korea
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• v.26 no.2
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• pp.155-168
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• 2023

Health geography has gained importance due to healthy smart cities, regions, and the integration of geo-internet and blockchain technologies. This study explores the intersection of geography and health, focusing on specific health challenges faced by individuals and groups. Using observational and descriptive methods, the study takes a regional approach to illuminate the socio-economic factors that are critical to addressing global health challenges. Drawing on academic literature and practical research, a concise case study of health challenges in Uzbekistan is presented, offering valuable insights. The analysis of data from informative articles and UN publications highlights the interdisciplinary nature of health geography and its practical applicability for researchers and policymakers. The findings underscore the important role of geography and health sciences in addressing region-specific diseases while highlighting the importance of spatial analysis in understanding environmental hazards and health impacts, including disease outbreaks.

• Science of Emotion and Sensibility
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• v.26 no.4
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• pp.115-124
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• 2023

This study explores the intersection of literary studies and artificial intelligence (AI), focusing on the common theme of human emotions to foster complementary advancements in both fields. By adopting a comparative perspective, the paper investigates emotion as a shared focal point, analyzing various emotion-related concepts from both literary and AI perspectives. Despite the scarcity of research on the fusion of AI and literary studies, this study pioneers an interdisciplinary approach within the humanities, anticipating future developments in AI. It proposes that literary sensibility can contribute to AI by formalizing subjective literary emotions, thereby enhancing AI's understanding of complex human emotions. This paper's methodology involves the terminology-centered extraction of emotions, aiming to blend subjective imagination with objective technology. This fusion is expected to not only deepen AI's comprehension of human complexities but also broaden literary research by rapidly analyzing diverse human data. The study emphasizes the need for a collaborative dialogue between literature and engineering, recognizing each field's limitations while pursuing a convergent enhancement that transcends these boundaries.

• IEMEK Journal of Embedded Systems and Applications
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• v.19 no.1
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• pp.47-55
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• 2024

We spend a lot of time in indoor space, and the space has a huge impact on our lives. Interior design plays a significant role to make an indoor space attractive and functional. However, it should consider a lot of complex elements such as color, pattern, and material etc. With the increasing demand for interior design, there is a growing need for technologies that analyze these design elements accurately and efficiently. To address this need, this study suggests a deep learning-based design analysis system. The proposed system consists of a semantic segmentation model that classifies spatial components and an image classification model that classifies attributes such as color, pattern, and material from the segmented components. Semantic segmentation model was trained using a dataset of 30000 personal indoor interior images collected for research, and during inference, the model separate the input image pixel into 34 categories. And experiments were conducted with various backbones in order to obtain the optimal performance of the deep learning model for the collected interior dataset. Finally, the model achieved good performance of 89.05% and 0.5768 in terms of accuracy and mean intersection over union (mIoU). In classification part convolutional neural network (CNN) model which has recorded high performance in other image recognition tasks was used. To improve the performance of the classification model we suggests an approach that how to handle data that has data imbalance and vulnerable to light intensity. Using our methods, we achieve satisfactory results in classifying interior design component attributes. In this paper, we propose indoor space design analysis system that automatically analyzes and classifies the attributes of indoor images using a deep learning-based model. This analysis system, used as a core module in the A.I interior recommendation service, can help users pursuing self-interior design to complete their designs more easily and efficiently.

• Clinical Endoscopy
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• v.55 no.3
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• pp.390-400
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• 2022

Background/Aims: Previous artificial intelligence (AI) models attempting to segment gastric intestinal metaplasia (GIM) areas have failed to be deployed in real-time endoscopy due to their slow inference speeds. Here, we propose a new GIM segmentation AI model with inference speeds faster than 25 frames per second that maintains a high level of accuracy. Methods: Investigators from Chulalongkorn University obtained 802 histological-proven GIM images for AI model training. Four strategies were proposed to improve the model accuracy. First, transfer learning was employed to the public colon datasets. Second, an image preprocessing technique contrast-limited adaptive histogram equalization was employed to produce clearer GIM areas. Third, data augmentation was applied for a more robust model. Lastly, the bilateral segmentation network model was applied to segment GIM areas in real time. The results were analyzed using different validity values. Results: From the internal test, our AI model achieved an inference speed of 31.53 frames per second. GIM detection showed sensitivity, specificity, positive predictive, negative predictive, accuracy, and mean intersection over union in GIM segmentation values of 93%, 80%, 82%, 92%, 87%, and 57%, respectively. Conclusions: The bilateral segmentation network combined with transfer learning, contrast-limited adaptive histogram equalization, and data augmentation can provide high sensitivity and good accuracy for GIM detection and segmentation.

• Journal of Information Science Theory and Practice
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• v.12 no.3
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• pp.14-35
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• 2024

This qualitative study explores cyberbullying among college students through Habermas's Theory of Communicative Action to examine the dissonance between online interactions and principles of rational discourse. Cyberbullying is a pervasive issue in digital communication that undermines logical, evidence-based conversation, fostering environments where misinformation, manipulation, and harm thrive. By analyzing case studies from three universities, the research identifies the characteristics, dynamics, and emotional impacts of cyberbullying on victims, highlighting the role of social media platforms in facilitating these negative interactions. The findings reveal significant challenges to authentic and equal online conversations, driven by power imbalances and a lack of genuine communication, leading to psychological distress, erosion of self-esteem, and changes in behavior among victims. The study underscores the potential of social media design and policy interventions to mitigate cyberbullying, emphasizing the need for educational programs, technological solutions, and community support to promote a safer, more respectful digital environment. Key themes include the dynamics of cyberbullying, the suppression of rational discourse, the psychological and emotional consequences of inauthentic communication, and strategies for resilience and recovery. The research contributes to understanding cyberbullying's complexities and suggests a multifaceted approach to addressing it, aligning with Habermas's ideal of communicative rationality to foster healthier online communities. Future research should further explore the intersection of technology design, user behavior, and regulatory policies to combat cyberbullying effectively.