• Title/Summary/Keyword: internal stability

Search Result 1,114, Processing Time 0.03 seconds

Enhancement of Anticancer Activities of Ephedra sinica, Angelica gigas by Ultra High Pressure Extraction (초고압 추출 처리에 의한 마황과 당귀의 항암 활성 증진)

  • Jeong, Hyang-Suk;Han, Jae-Gun;Ha, Ji-Hye;Kim, Young;Oh, Sung-Ho;Kim, Seoung-Seop;Jeong, Myoung-Hoon;Choi, Geun-Pyo;Park, Uk-Yeon;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
    • /
    • v.17 no.2
    • /
    • pp.102-108
    • /
    • 2009
  • This study was performed to enhance anticancer activities of E. sinica, and A. gigas by ultra high pressure extraction process. The cytotoxicity of E. sinica and A. gigas on human kidney cell (HEK293) was as low as 24.94% and 25.3% in adding 1.0 $mg/m{\ell}$ of the sample extracted at 500 Mpa for 15 minute. Generally, the inhibition of cancer cell growth on A549 and MCF-7 was increased over 20% in the ultra high pressure samples, compared to the conventional extraction process. Under the extracts from ultra high pressure process showed not only the strongest anticancer activities, but also had better stability than normal extracts. It was also found that the extracts of A. gigas reduced the hypertrophy of the internal organs, such as adrenal and spleen caused stresses in several mouse models.

Thermotropic Liquid Crystalline Properties of Cholesteryloxycarbonated and (Cholesteryloxycarbonyl) alkanoated Celluloses (콜레스테릴옥시카본화 그리고 (콜레스테릴옥시카보닐)알카노화 셀룰로오스들의 열방성 액정 특성)

  • Jeong, Seung-Yong;Ma, Yung-Dae
    • Polymer(Korea)
    • /
    • v.32 no.2
    • /
    • pp.169-177
    • /
    • 2008
  • The thermal and optical properties of cellulose tri(cholesteryloxy) carbonate(CCE0) and cellulose tri(cholesteryloxycarbonyl)alkanoates (CCEn, n=$2{\sim}8$, 10, the number of methylene units in the spacer) were investigated. CCE0 formed an enantiotropic cholesteric phase, whereas all the CCEn exhibited monotropic cholesteric phases. CCEn with n=$3{\sim}8$ formed cholesteric phases with left-handed helical structures whose optical pitches (${\lambda}_m's$) decrease with increasing temperature. On the other hand, CCE0 and CCEn with n=2 or 10 did not display reflection colors over the full cholesteric range, suggesting that the helical twisting power of the cholesteryl group highly depends on the length of the spacer connecting the cholesteryl group to the main chain. The thermal stability and degree of order in the mesophase and the temperature dependence of the ${\lambda}_m$ observed for CCEn highly depended on n. The results were discussed in terms of the differences in the internal plasticization, the arrangement of the side groups, and the conformation of the molecules.

NUMERICAL ANALYSIS FOR TURBULENT FLOW AND AERO-ACOUSTICS AROUND A THREE DIMENSIONAL CAVITY WITH HIGH ASPECT RATIO (3차원 고세장비 공동 주위의 난류유동 및 음향 특성에 관한 수치적 연구)

  • Mun, P.U.;Kim, J.S.
    • Journal of computational fluids engineering
    • /
    • v.15 no.2
    • /
    • pp.7-13
    • /
    • 2010
  • Flight vehicles such as wheel wells and bomb bays have many cavities. The flow around a cavity is characterized as an unsteady flow because of the formation and dissipation of vortices brought by the interaction between the free stream shear layer and the internal flow of the cavity. The resonance phenomena can damage the structures around the cavity and negatively affect the aerodynamic performance and stability of the vehicle. In this study, a numerical analysis was performed for the cavity flows using the unsteady compressible three-dimensional Reynolds-Averaged Navier-Stokes (RANS) equation with Wilcox's turbulence model. The Message Passing Interface (MPI) parallelized code was used for the calculations by PC-cluster. The cavity has aspect ratios (L/D) of 5.5 ~ 7.5 with width ratios (W/D) of 2 ~ 4. The Mach and Reynolds numbers are 0.4 ~ 0.6 and $1.6{\times}10^6$, respectively. The occurrence of oscillation is observed in the "shear layer and transient mode" with a feedback mechanism. Based on the Sound Pressure Level (SPL) analysis of the pressure variation at the cavity trailing edge, the dominant frequencies are analyzed and compared with the results of Rossiter's formula. The dominant frequencies are very similar to the result of Rossiter's formula and other experimental datum in the low aspect ratio cavity (L/D = ~4.5). In the high aspect ratio cavity, however, there are other low dominant frequencies of the leading edge shear layer with the dominant frequencies of the feedback mechanism.

Analysis of the Characteristics of Ground Reaction Force According to the Level of Knee Osteoarthritis During Gait (보행 시 농작업 종사자들의 슬관절 퇴행성 등급에 따른 지면반력 특성 분석)

  • Lee, Kyung-Ill;Lee, Chul-Gab;Hong, Wan-Ki;Kim, Min
    • Korean Journal of Applied Biomechanics
    • /
    • v.25 no.4
    • /
    • pp.393-399
    • /
    • 2015
  • Objective : This study was conducted with an aim to use it as basic data for developing assistive devices, such as insoles that can suppress the progress of degenerative diseases and strategies, to improve early degenerative diseases by assessing walking characteristics of farm workers who were classified as KL-grade in the perspective of motor mechanics. Method : 38 male and female adults who complained of knee joint pain for more than six months were selected, and they were classified according to KL-grade. KL-grade was assessed by an orthopaedic specialist and an occupational environment health specialist. Filming equipment (FX-1, CASIO, Japan) and a ground reaction force system (AMTI OR6, AMTI, USA) were used to identify ground reaction force characteristics, and WOMAC was used for a pain rating scale. Results : There was a difference between the right and left side (axis-X) according to KL-grade, and when the grade was higher, the internal ground reaction force was also higher. Changes in COP were not affected by KL-grade of the knee joint, but it tended to increase as the grade increased. There were differences in the time required for limb support while walking according to the grades, and when the grade was higher, walking was more inefficient with long braking force and short propulsion forces. Also, pain rating scale, the right and left side, and COP changes while in support phase were related. Conclusion : There was a partial, statically significant difference in KL-grade and ground reaction force occurring during the support phase, and there were differences in ground reaction forces according to the grades of degenerative arthritis in the knee joint, indicating that this study is worthy as basic data for future studies.

Sintering and Characterization of SiC-matrix Composite Including TRISO Particles (TRISO 입자를 포함하는 SiC 복합소결체의 소결 및 특성 평가)

  • Lee, Hyeon-Geun;Kim, Daejong;Park, Ji Yeon;Kim, Weon-Ju
    • Journal of the Korean Ceramic Society
    • /
    • v.51 no.5
    • /
    • pp.418-423
    • /
    • 2014
  • Fully ceramic micro encapsulated (FCM) nuclear fuel is a concept recently proposed for enhancing the stability of nuclear fuel. FCM nuclear fuel consists of tristructural-isotropic (TRISO) fuel particles within a SiC matrix. Each TRISO fuel particle is composed of a $UO_2$ kernel and a PyC/SiC/PyC tri-layer which protects the kernel. The SiC ceramic matrix is created by sintering. In this FCM fuel concept, fission products are protected twice, by the TRISO coating layer and by the SiC ceramic. The SiC ceramic has proven attractive for fuel applications owing to its low neutron-absorption cross-section, excellent irradiation resistivity, and high thermal conductivity. In this study, a SiC-matrix composite containing TRISO particles was sintered by hot pressing with $Al_2O_3-Y_2O_3$ additive system. Various sintering conditions were investigated to obtain a relative density greater than 95%. The internal distribution of TRISO particles within the SiC-matrix composite was observed using an x-ray radiograph. The fracture of the TRISO particles was investigated by means of analysis of the cross-section of the SiC-matrix composite.

The Strength and Deformation Characteristics of Jumunjin Sand under Low Confining Stresses (낮은 구속응력에 대한 주문진 표준사의 강도 및 변형 특성)

  • Han, Young-Chul;Lim, Hyun-Sung;Jeong, Sang-Seom
    • Journal of the Korean Geotechnical Society
    • /
    • v.30 no.2
    • /
    • pp.33-42
    • /
    • 2014
  • The shear strength and deformation characteristics of granular soils at low confining stresses differ from those with high confining stresses. Thus, the clear understanding of geotechnical problems related to the low confining stress state such as the stability of shallow foundations, embankments, slope failure, debris flow characteristics and liquefaction as well as the various laboratory model tests is needed. In this study, drained triaxial compression tests with the cell pressures from 5 kPa to 300 kPa were performed on dry Jumunjin sand. The results show that the internal friction angle and deformation modulus are dependent on the confining stress. Also, the correlations between them on the dense and loose sand were established.

A Study Analyzing Donation Cases for Establishing Library Corporate Donation Culture (도서관 기부문화 정착을 위한 기업기부 사례분석 연구)

  • Noh, Younghee
    • Journal of the Korean Society for Library and Information Science
    • /
    • v.48 no.2
    • /
    • pp.109-135
    • /
    • 2014
  • Library is a social institution that satisfies the intellectual needs of the community and provides information, cultural enjoyment, and continuing education to the community. However, it is true that a library may face with difficulties in satisfying the diverse and advanced needs of its users and performing its newly acquired roles because of the limited financial resources of state and local governments. Therefore, this study proposed the introduction of corporate donations as one of the options for library funding, both for expansion of critical library infrastructure and for the internal stability of library operations. To this end, this study determined corporate donation goals, donation targets, campaign donations, the number of libraries being built and renovated, and the effects on libraries that obtained corporate donations by investigating and analyzing known corporate donation cases. The results of this study could be used by libraries hoping to attract corporate donations.

Selective Recovery of the SSD TRIM Command in Digital Forensics (디지털 포렌식 관점에서 SSD TRIM 명령의 선별적 복구)

  • Hwang, Hyun Ho;Park, Dong Joo
    • KIPS Transactions on Computer and Communication Systems
    • /
    • v.4 no.9
    • /
    • pp.307-314
    • /
    • 2015
  • Recently, market trends of auxiliary storage device HDD and SSD are interchangeable. In the future, the SSD is expected to be used more popular than HDD as an auxiliary storage device. The TRIM command technique has been proposed and used effectively due to the development of the SSD. The TRIM command techniques can be used to solve the problem of Freezing SSD that operating system cooperates with the SSD. The TRIM command techniques are performed in the idle time of the internal SSD that are actually deleted when a user deletes the data. However, in the point of view of computer forensics, the digital crime is increasing year by year due to lack of data recovery. Thus, this rate of arrest is insufficient. In this paper, I propose a solution that selectively manages data to delete based on advantage of the stability and the write speed of the TRIM command. Through experiments, It is verified by measuring the performance of the traditional method and selected method.

Integrated Tree Crops-ruminants Systems in South East Asia: Advances in Productivity Enhancement and Environmental Sustainability

  • Devendra, C.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.24 no.5
    • /
    • pp.587-602
    • /
    • 2011
  • Improved efficiency in the use of natural resources, pragmatic production systems and environmental sustainability, justified by the need for improved land use systems and increased productivity, are discussed in the context of Asian integrated systems, diversification, and issues of sustainability. The importance of these are reflected by serious inadequate animal protein production throughout Asia, where available supplies cannot match current and projected human requirements up to 2050. Among the ruminant production systems, integrated tree crops-ruminant production systems are grossly underestimated and merit emphasis and expansion. As an example, integrated oil palm- based system is an important pathway for integration with ruminants (buffaloes, cattle, goats and sheep), and provides the entry point for development. The importance and benefits of integrated systems are discussed, involving animals with annual and perennial tree crops, integration with aquaculture, the significance of crop-animal interactions, stratification of the systems, production options, improved use of forages and legumes, potential for enhanced productivity, implications for improved livelihoods of the rural poor and the stability of farm households. The advances in research and development in South East Asia highlight demonstrable increased productivity from animals and meat offtakes, value addition to the oil palm crop, sustainable development, and distinct economic impacts. The results from 12 out of a total of 24 case studies concerning oil palm over the past three decades showed increased yield of 0.49-3.52 mt of fresh fruit bunches (FFB)/ha/yr; increased income by about 30%; savings in weeding costs by 47- 60% equivalent to 21-62 RM/ha/yr; and an internal rate of return of 19% based on actual field data. The results provide important socio-economic benefits for resource-poor small farmers. Potential increased offtakes and additional income exist with the integration of goats. Additionally, the potential for carbon sequestration with tree crops is an advantage. The reasons for low adoption of the syatems are poor awareness of the potential of integrated systems, resistance by the crop- oriented plantation sector, and inadequate technology application. Promoting wider expansion and adoption of the systems in the future is linked directly with coherent policy, institutional commitment, increased investments, private sector involvement, and a stimulus package of incentives.

Sloshing suppression by floating baffle

  • Kang, Hooi-Siang;Md Arif, Ummul Ghafir;Kim, Kyung-Sung;Kim, Moo-Hyun;Liu, Yu-Jie;Lee, Kee-Quen;Wu, Yun-Ta
    • Ocean Systems Engineering
    • /
    • v.9 no.4
    • /
    • pp.409-422
    • /
    • 2019
  • Sloshing is a phenomenon which may lead to dynamic stability and damages on the local structure of the tank. Hence, several anti-sloshing devices are introduced in order to reduce the impact pressure and free surface elevation of liquid. A fixed baffle is the most prevailing anti-sloshing mechanism compared to the other methods. However, the additional of the baffle as the internal structure of the LNG tank can lead to frequent damages in long-term usage as this structure absorbs the sloshing loads and thus increases the maintenance cost and downtime. In this paper, a novel type of floating baffle is proposed to suppress the sloshing effect in LNG tank without the need for reconstructing the tank. The sloshing phenomenon in a membrane type LNG tank model was excited under sway motion with 30% and 50% filling condition in the model test. A regular motion by a linear actuator was applied to the tank model at different amplitudes and constant period at 1.1 seconds. Three pressure sensors were installed on the tank wall to measure the impact pressure, and a high-speed camera was utilized to record the sloshing motion. The floater baffle was modeled on the basis of uniform-discretization of domain and tested based on parametric variations. Data of pressure sensors were collected for cases without- and with-floating baffle. The results indicated successful reduction of surface run-up and impulsive pressure by using a floating baffle. The findings are expected to bring significant impacts towards safer sea transportation of LNG.