• 한국벤처창업학회:학술대회논문집
• /
• 한국벤처창업학회 2021년도 춘계학술대회
• /
• pp.33-42
• /
• 2021

Based on the findings of Lee et al.(2020) and Lee & Oh(2021), this paper aims to fill the gap in our knowledge regarding the relationship between strategic choices and corporate growth by utilizing a novel dataset of 'Unicorn' and 'Hyper-growing' companies. Two previous studies provide coherent findings that the relationship between firms' strategies and their performance should be explored under a more comprehensive framework with consideration of both internal and external factors. Therefore, in this study, we apply a single conceptual framework to two different datasets, which considers the strategy factors as independent variables, and the industry(market) and the firm age as moderating variables. For our dependent variables, valuations for unicorn companies and revenue CAGR for hyper-growing companies are used after categorizing them into three uniform groups. The strategy variables include 'Generic (Cost-leadership, Differentiation, focus) strategies', 'Growth(Organic, M&A) strategies', 'Leading(Pioneer, Fast-follower) strategies', 'Target market(B2B, B2C, B2G, C2C) strategies', 'Global(Global, Local) strategies', 'Digital(Online, Offline) strategies.' For industry(market) factors, it consists of historical growth rate for industries and economic, demographic, and regulatory aspects of states and countries. To overcome the differences in their units, they are also uniformly categorized into multiple groups. Before we conduct a regression analysis, we analyze the industry distribution of the 'Unicorn' and the 'Hyper-growing' companies with descriptive statistics at the integrated and individual levels. Next, we employ hierarchical regression models on Study A('Unicorn' companies in 2019) and Study B('Hyper-growing' companies in 2019) under the same comprehensive framework. We then analyze the relationship between the 'strategy' and the 'performance' factors with two different approaches: 1) an integrated regression model with both the sample of Study A and B and 2) respective regression models on Study A and B. This empirical study aims to provide a complete understanding and a reference to which strategy factors should be considered to promote firms' scale-up and growth.

• 동의신경정신과학회지
• /
• 제34권4호
• /
• pp.369-384
• /
• 2023

Objectives: The purpose of this study was to review the recent clinical studies on Korean medicine for treatment of eating disorders. Methods: We searched clinical studies that verified the effectiveness of Korean medicine for the treatment of eating disorders. The search was done in 9 databases (Korean, Chinese, and English databases) from January 2016 to August 2023. Results: A total of 10 articles were retrieved. The articles were classified based on the type of study design: 1 database study, 2 case series, and 7 case reports. Among the articles, in 4 articles, acupuncture was used as a treatment intervention for bulimia nervosa, and in 6 articles herbal medicine was used as a treatment intervention for anorexia nervosa. The most frequent pattern identification was 'Liver qi depression', the most composed herb was 'Root of Glycyrrhiza uralensis (甘草)', and the most used acupoints were CV12 and SP6. All the studies showed positive results. Conclusions: Korean medicine for eating disorders treatments might be effective. However, the quality of evidence in the selected studies was low, and there was no comparison of the treatment effects using objective diagnostic tools. For more accurate results, systematically designed clinical studies using objective diagnostic tools should be conducted.

• Korean Journal of Radiology
• /
• 제25권3호
• /
• pp.301-313
• /
• 2024

Objective: The current body of evidence lacks clarity regarding the comparative efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) as minimally invasive treatments for benign thyroid nodules. The primary objective of this study is to clarify these concerns. Materials and Methods: A comprehensive search was conducted using the Cochrane Library, Scopus, Europe PMC, and Medline databases until October 10th, 2023, using a combination of relevant keywords. This study incorporated literature that compared RFA and MWA for benign thyroid nodules. The primary outcome was the volume reduction ratio (VRR) from baseline to follow-up. Secondary outcomes were symptom score, cosmetic score, ablation time, major complications rate, hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. We used Risk of Bias in Non-randomized Studies - of Interventions (ROBINS-I) tool to assess the risk of bias in the included studies. We employed random effects models to analyze the standardized mean difference (SMD) and odds ratio for the presentation of outcomes. Results: Nine studies with 2707 nodules were included. The results of our meta-analysis indicated similar efficacy between RFA and MWA in terms of VRR during the 1 (SMD 0.06; 95% confidence interval [CI]: -0.13 to 0.26; P = 0.52) and 3 (SMD 0.11; 95% CI: -0.03 to 0.25; P = 0.12) months of follow-up. VRR was significantly higher in RFA than in MWA at the 6 (SMD 0.25; 95% CI: 0.06-0.43; P = 0.008) and 12 month of follow-up (SMD 0.38; 95% CI: 0.17 to 0.59; P < 0.001). There were no significant differences between RFA and MWA in symptom scores, cosmetic scores, or the incidence of complications, including hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. Conclusion: RFA showed a higher VRR than MWA at 6 and 12-month follow-ups, with a comparable safety profile.

• 마케팅과학연구
• /
• 제18권2호
• /
• pp.19-45
• /
• 2008

본 연구는 인터넷쇼핑몰 비주얼 머천다이징의 주요차원을 고객이 쇼핑몰에 진입한 후 정보탐색과 대안평가를 거치는 등의 쇼핑과정을 토대로 AIDA모형 관점에서 점포, 제품, 촉진에 초점을 맞추었다. VMD의 주요차원(primary dimensions)으로는 점포디자인, 머천다이징, 그리고 머천다이징단서로 구분하였다. 선행연구 결과를 토대로 점포다자인의 하위차원으로는 차별성, 간결성, 위치확인성을, 머천다이즈의 하위차원으로는 제품구색, 명성, 정보성을, 그리고 머천다이징단서의 하위차원으로는 제품추천 및 링크를 설정하여 VMD태도와의 관계를 탐색적으로 조사하였다. 연구결과 이들 세 차원은 종속변수에 유의한 정의 영향을 미치는 것으로 나타났다.

• Tuberculosis and Respiratory Diseases
• /
• 제43권4호
• /
• pp.613-622
• /
• 1996

교착성 세기관지염은 매우 드문 소기도질환의 하나로서 변리학적으로 증식성 세기관지염과 더불어 폐쇄성 세기관지염의 양축의 하나를 점하고 있다. BOOP로 대표되는 증식성 세 기관지염은 임상경과가 비교적 빠르고 방사선학적으로도 간질성 또는 폐포성 음영 을 동반하는 비정형 폐렴과 유사한 발현을 보이므로 실제의 빈도가 적지 않다는 점은 제외하더라도 비교적 쉽게 의심하고 진단에 이를 수 있는 질환인 반면, 교착성 세기관지염은 그 빈도 자체가 매우 드물 뿐더러 방사선 소견이 거의 정상이고 폐기능검사 소견도 폐쇄성 양상을 보이므로 임상적으로 대개는 만성폐쇄성폐질환으로 간과되기 쉬운 질환으로써 그 진단이 쉽지 않다. 치료적인 면에서도 증식성 세기관지염이 부신피질호르몬제에 대해 극적인 반응을 보이는 반면 교착성 세기관지염은 세기관지벽 전체가 섬유성 반흔으로 대치되어 비가역성 기도폐쇄가 초래하는 병리학적 특성이 시사하는 바와 같이 치료에 대한 반응이 매우 미약한 치명적 질환이다. 그 원인으로서는 증식성 및 교착성 세기관지염 모두에서 독성 물질에 의한 흡입성 폐손상, 약제성, 감염성, 교원질환 관련성, 장기 이식 후등 선행 요인이 있는 경우와 원발 요인이 없는 경우를 특발성이라 한다. 같은 선행 요인에 의해 두가지 다른 질환군이 초래된다는 사실에서 이들이 같은 질환의 한 spectrum상에 있다는 설명도 있고, 여러 원인에 대해 같은 조직 소견이 관찰된다는 점에서 질환 특이적 병리 소견이라기보다는 비특이적 조직 반응의 하나라는 설명도 있지만 이에 대해서는 추후 연구가 필요한 실정이다. 저자 등은 비 Hodgkin 림프종을 진단 받은 동일한 시점에서 비교적 빠르게 진행하는 만성기도폐쇄 양상을 나타내고, 만성폐쇄성폐질환에 대한 위험 인자가 없고 흉부 방사선 소견상 정상소견을 나타내는 47세 여자 환자에서 개흉폐생검을 실시하여 교착성 세기관지염을 진단하였기에 문헌 고찰과 함께 보고하는 바이다. 상기한 선행 요인이 확인되지 않아 특발성이라 판단되며, 악성 종양, 특히 림프종과의 관련성 여부에 대해서는 현재로서는 확언하기 어렵고 향후 연구가 필요한 사항이라 생각된다.

• Journal of Chest Surgery
• /
• 제52권4호
• /
• pp.248-329
• /
• 2019

Background: Though clinical practice guidelines (CPGs) for cardiac rehabilitation (CR) are an effective and widely used treatment method worldwide, they are as yet not widely accepted in Korea. Given that cardiovascular disease is the second leading cause of death in Korea, it is urgent that CR programs be developed. In 2008, the Government of Korea implemented CR programs at 11 university hospitals as part of its Regional Cardio-Cerebrovascular Center Project, and 3 additional medical facilities will be added in 2019. In addition, owing to the promotion of CR nationwide and the introduction of CR insurance benefits, 40 medical institutions nationwide have begun CR programs even as a growing number of medical institutions are preparing to offer CR. The purpose of this research was to develop evidence-based CPGs to support CR implementation in Korea. Methods: This study is based on an analysis of CPGs elsewhere in the world, an extensive literature search, a systematic analysis of multiple randomized control trials, and a CPG management, development, and assessment committee comprised of 33 authors-primarily rehabilitation specialists, cardiologists, and thoracic surgeons in 21 university hospitals and 2 general hospitals. Twelve consultants, primarily rehabilitation, sports medicine, and preventive medicine specialists, CPG experts, nurses, physical therapists, clinical nutritionists, and library and information experts participated in the research and development of these CPGs. After the draft guidelines were developed, 3 rounds of public hearings were held with staff members from relevant academic societies and stakeholders, after which the guidelines were further reviewed and modified. Results: CR involves a more cost-effective use of healthcare resources relative to that of general treatments, and the exercise component of CR lowers cardiovascular mortality and readmission rates, regardless of the type of coronary heart disease and type and setting of CR. Conclusion: Individualized CR programs should be considered together with various factors, including differences in heart function and lifestyle, and doing so will boost participation and adherence with the CR program, ultimately meeting the final goals of the program, namely reducing the recurrence of myocardial infarction and mortality rates.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권4호
• /
• pp.2159-2165
• /
• 2013

Cancer registries help to establish and maintain cancer incidence reporting system, serve as a resource for investigation of cancer and its causes, and provide information for planning and evaluation of preventive and control programs. However, their wider role in directly enhancing oncology drug access has not been fully explored. We examined the value of cancer registries in oncology drug access in the Asia-Pacific region on three levels: (1) specific registry variable types; (2) macroscopic strategies on the national level; and (3) a regional cancer registry network. Using literature search and proceedings from an expert forum, this paper covers recent cancer registry developments in eight economies in the Asia-Pacific region - Australia, China, Hong Kong, Malaysia, Singapore, South Korea, Taiwan, and Thailand - and the ways they can contribute to oncology drug access. Specific registry variables relating to demographics, tumor characteristics, initial treatment plans, prognostic markers, risk factors, and mortality help to anticipate drug needs, identify high-priority research area and design access programs. On a national level, linking registry data with clinical, drug safety, financial, or drug utilization databases allows analyses of associations between utilization and outcomes. Concurrent efforts should also be channeled into developing and implementing data integrity and stewardship policies, and providing clear avenues to make data available. Less mature registry systems can employ modeling techniques and ad-hoc surveys while increasing coverage. Beyond local settings, a cancer registry network for the Asia-Pacific region would offer cross-learning and research opportunities that can exert leverage through the experiences and capabilities of a highly diverse region.

• 식물병연구
• /
• 제25권4호
• /
• pp.220-225
• /
• 2019

2018년 경북 김천 지역 포도 하우스 재배 농가에서 포도송이가 무르고 마른 포도 과실이 낙과되는 피해가 발생하였다. 병반 표면에는 검갈색의 곰팡이 포자가 형성된 것을 확인할 수 있었으며, 이병과실에서 병원균을 분리하여 균학적 특징 및 염기서열 분석결과 병원균은 Aspergillus tubingensis로 동정하였다. 이 증상의 원인균을 증명하기 위해 이병과실에서 병원균을 분리하여 병원성 검정을 수행한 결과, 고온으로 갈수록 급격히 병이 진전되고 하우스에서 발생한 병징과 일치하였다. 또한, 포도송이 썩음 병원균에 대하여 화학농약 약제의 선발을 통해 병원균의 확산을 막고 예방을 하고자 단제 7종 균사생장 억제 효과 검정을 실시하였다. Dipenoconazole, tebuconazole, metconazole, iminoctadine, captan 5가지의 약제에서 균사생장 억제 효과가 확인되었다. A. tubingensis에 의한 포도송이썩음병(가칭)은 2018년도부터 국내 샤인머스켓 포도에 처음 발생되고 있음을 보고하고, 효과적으로 포도송이썩음병의 발생을 예방할 수 있는 5종의 약제를 보고한다.

• 대한핵의학회지
• /
• 제35권3호
• /
• pp.142-151
• /
• 2001

목적: 높은 숙련도의 국어와 낮은 숙련도의 영어의 단어들을 사용하는 시각 과제에서 어의처리에 매개되는 뇌 신경회로의 공통요소와 특이요소를 탐색하고자 하였다. 대상 및 방법: 정상인 13명을 대상으로 국어단어에 대한 어의처리 과제, 영어단어에 대한 어의처리 과제, 단순 도형을 이용한 대조과제 등 세 가지 인지과제를 주고, 과제 수행 동안 $[^{15}O]H_2O$를 추적자로 한 양전자방출단층촬영을 실시한 후 감산분석을 통해 두 언어에 대한 어의처리 과정에 공통적으로 관여하는 뇌영역과 각각에 특이하게 작용하는 뇌영역을 탐색하였다. 결과: 국어 및 영어단어에 공통적으로 어의처리 과정에 좌측 편측성의 방추상이랑(fusiform gyrus)의 활성화가 관찰되었고, 추가적으로 영어단어의 경우 좌측 하측두이랑(inferior temporal gyrus)의 활성화가 관찰되었다. 국어단어에 특이한 어의처리 영역은 우측 일차청각영역을 포함하는 뇌 전반에 걸친 다발성 활성화가 특징이었던데 반해, 영어단어에 특이한 어의처리 영역은 우측 시각영역에 한정된 양상이었다. 결론: 높은 숙련도의 국어단어를 이용한 시각적 과제수행에는 내적 음운처리가 중요한데 비해, 낮은 숙련도의 영어단어를 이용한 과제수행의 경우에는 주로 시각적 주사(visual scanning)가 중요한 요소를 구성한다.

• The Korean Journal of Pain
• /
• 제30권1호
• /
• pp.34-43
• /
• 2017

Background: We sought to determine the association between chronic pain and participating in routine health screening in a low socioeconomic-status (SES) rental-flat community in Singapore. In Singapore, ${\geq}85%$ own homes; public rental flats are reserved for those with low-income. Methods: Chronic pain was defined as pain ${\geq}3$ months. From 2009-2014, residents aged 40-60 years in five public rental-flat enclaves were surveyed for chronic pain; participation in health screening was also measured. We compared them to residents staying in adjacent owner-occupied public housing. We also conducted a qualitative study to better understand the relationship between chronic pain and health screening participation amongst residents in these low-SES enclaves. Results: In the rental-flat population, chronic pain was associated with higher participation in screening for diabetes (aOR = 2.11, CI = 1.36-3.27, P < 0.001), dyslipidemia (aOR = 2.06, CI = 1.25-3.39, P = 0.005), colorectal cancer (aOR = 2.28, CI = 1.18-4.40, P = 0.014), cervical cancer (aOR = 2.65, CI = 1.34-5.23, P = 0.005) and breast cancer (aOR = 3.52, CI = 1.94-6.41, P < 0.001); this association was not present in the owner-occupied population. Three main themes emerged from our qualitative analysis of the link between chronic pain and screening participation: pain as an association of "major illness"; screening as a search for answers to pain; and labelling pain as an end in itself. Conclusions: Chronic pain was associated with higher cardiovascular and cancer screening participation in the low-SES population. In low-SES populations with limited access to pain management services, chronic pain issues may surface during routine health screening.