• Title/Summary/Keyword: internal medicine

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A Case of Prothionamide Induced Hepatitis on Patient with Multi-Drug Resistant Pulmonary Tuberculosis (다제내성 결핵환자에서 Prothionamide에 의한 급성 간염 1예)

  • Park, Jun-Beom;Park, Byung-Hoon;Son, Ji-Young;Jung, Ji-Ye;Kim, Eun-Young;Lim, Ju-Eun;Lee, Sang-Hoon;Lee, Sang-Kook;Kim, Song-Yee;Jung, Won-Jai;Lim, Seung-Taek;Lee, Kyung-Jong;Kang, Young-Ae;Kim, Young-Sam;Kim, Se-Kyu;Chang, Joon;Choi, Jun-Jeong;Park, Moo-Suk
    • Tuberculosis and Respiratory Diseases
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    • v.70 no.3
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    • pp.251-256
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    • 2011
  • The prevalence of multi-drug resistant tuberculosis (MDR-TB), which is resistant to isoniazid and rifampin, has been increasing in Korea. And the side effects of 2nd line anti-tuberculosis medications, including drug-induced hepatitis, are well known. Although prothionamide (PTH) is one of the most useful anti-TB medications and although TB medication-induced acute hepatitis is a severe complication, there are only a few published case reports about prothionamide induced hepatitis. In this case report, a 22 year old male was diagnosed with pulmonary MDR-TB and was administered 2nd line anti-TB mediations, including PTH. Afterwards, he had a spiking fever and his liver enzymes were more than 5 times greater than the upper limit of the normal range. He was then diagnosed with drug-induced hepatitis by liver biopsy. His symptoms and liver enzyme elevation were improved after stopping PTH. Accordingly, we report this case of an association between PTH and acute hepatitis.

A Case of Passive Smoking Induced Respiratory Bronchiolitis Associated Interstitial Lung Disease (간접흡연으로 유발된 호흡 세기관지염 연관 간질성 폐질환 1예)

  • Lee, Kyoung Ju;Kim, Jung Ha;Ha, Eun Sil;Jung, Jin Yong;Lee, Seung Hyeun;Kim, Se Joong;Lee, Eun Joo;Hur, Gyu Young;Jung, Hye Cheol;Lee, Sung Yong;Kim, Hyn Koo;Lee, Sang Yeub;Kim, Je Hyeong;Shin, Chol;Shim, Jae Jeong;In, Kwang Ho;Kang, Kyung Ho;Yoo, Se Hwa
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.5
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    • pp.541-545
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    • 2005
  • Respiratory bronchiolitis associated interstitial lung disease is a rare condition among current or ex-smokers, which has features consistent with interstitial lung disease. The presentations are non-specific, but symptoms generally include a cough and dyspnea on exertion, and its pathology is characterized by the accumulation of pigmented macrophages within the respiratory bronchioles and adjacent air spaces, and is associated with mild thickening of the peribronchiolar interstitium. Recently, the case of a 54-year-old woman passive smoker, diagnosed as having respiratory bronchiolitis associated interstitial lung disease, was experienced at our institution.

A Case Report of a Sporadic Spinocerebellar Ataxia Patient with Herniated Intervertebral Lumbar Discs Treated with Traditional Korean Medicine (요추 추간판 탈출증을 동반한 산발성 소뇌 운동실조 환자에 대한 한방치험 증례보고 1례)

  • Seo, Hye-jin;Kang, Ah-hyun;Han, Dong-geun;Sung, Jae-yeon;Oh, Ju-hyun;Lee, Yu-ra;Kang, Man-ho;Lee, Hyung-chul;Eom, Guk-hyeon;Song, Woo-sub
    • The Journal of Internal Korean Medicine
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    • v.39 no.5
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    • pp.994-1003
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    • 2018
  • Objective: The aim of this study was to report a clinical case suggesting the potential effects of traditional Korean medicine for the treatment of sporadic spinocerebellar ataxia in a patient with herniated intervertebral lumbar discs. Methods: The patient was treated with a series of Korean medicine treatments including the herbal medicine Zhenganxifeng-tang-gagam, acupuncture, pharmacoacupuncture, and electroacupuncture along with herniated intervertebral lumbar disc treatments. Results: Improvements of Numeric rating scale (NRS) and European Quality of Life-5 Dimensions (EQ-5D) score were observed after the treatment. Conclusion: Traditional Korean medicine has potential benefits for sporadic spinocerebellar ataxia patients with herniated intervertebral lumbar discs.

Infection Rate of Chlamydia pneumoniae in Patients with Chronic Cough (만성기침 환자에서 Chlamydia pneumoniae 감염률)

  • Chun, Seung-Yeon;Park, Kwon-Oh;Park, Yong-Bum;Choi, Jeong-Hee;Lee, Jae-Young;Mo, Eun-Kyung;Park, Sung-Hoon;Kim, Cheol-Hong;Lee, Chang-Youl;Hwang, Yong-Il;Jang, Seung-Hun;Shin, Tae-Rim;Park, Sang-Myeon;Kim, Dong-Gyu;Lee, Myung-Goo;Hyun, In-Gyu;Jung, Ki-Suck
    • Tuberculosis and Respiratory Diseases
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    • v.69 no.6
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    • pp.426-433
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    • 2010
  • Background: Persistent cough has recently been found to be associated with Chlamydia pneumoniae infection. We aimed to investigate the infection rate of C. pneumonia in adult patients with chronic cough. Methods: We recruited 68 patients with persistent cough lasting in excess of 3 weeks, who visited Kangdong Sacred Heart Hospital from January 2005 to August 2005. On the first visit, chest and paranasal sinuses radiography, skin prick test of common allergens, and induced sputum samples for C. pneumoniae were performed in all of patients. Further evaluation for diagnosis included a methacholine provocation test and eosinophil counts in induced sputum. Results: The most common cause of chronic cough was upper airway cough syndrome (UACS) (26.5%), followed by eosinophilic bronchitis (20.6%) and cough variant asthma (16.2%). Idiopathic chronic cough was the cause in 33.8% of patients. The mean duration of cough was 11.7 months. C. pneumoniae was isolated by polymerase chain reaction (PCR) from one patient who had upper respiratory air way syndrome. Conclusion: Chlamydia pneumoniae appears to have a minor role as a cause of chronic cough in patients.