• Title/Summary/Keyword: internal knowledge

Search Result 1,047, Processing Time 0.026 seconds

Generic and adaptive probabilistic safety assessment models: Precursor analysis and multi-purpose utilization

  • Ayoub, Ali;Kroger, Wolfgang;Sornette, Didier
    • Nuclear Engineering and Technology
    • /
    • v.54 no.8
    • /
    • pp.2924-2932
    • /
    • 2022
  • Motivated by learning from experience and exploiting existing knowledge in civil nuclear operations, we have developed in-house generic Probabilistic Safety Assessment (PSA) models for pressurized and boiling water reactors. The models are computationally light, handy, transparent, user-friendly, and easily adaptable to account for major plant-specific differences. They cover the common internal initiating events, frontline and support systems reliability and dependencies, human-factors, common-cause failures, and account for new factors typically overlooked in many PSAs. For quantification, the models use generic US reliability data, precursor analysis reports, the ETHZ Curated Nuclear Events Database, and experts' opinions. Moreover, uncertainties in the most influential basic events are addressed. The generated results show good agreement with assessments available in the literature with detailed PSAs. We envision the models as an unbiased framework to measure nuclear operational risk with the same "ruler", and hence support inter-plant risk comparisons that are usually not possible due to differences in plant-specific PSA assumptions and scopes. The models can be used for initial risk screening, order-of-magnitude precursor analysis, and other research/pedagogic applications especially when no plant-specific PSAs are available. Finally, we are using the generic models for large-scale precursor analysis that will generate big picture trends, lessons, and insights.

A Study on Aspects of Transmedial Enjoyment of Game Users (게임 사용자의 트랜스미디어적 향유 양상 연구)

  • Ahn, Jin-Kyoung
    • Journal of Convergence for Information Technology
    • /
    • v.11 no.8
    • /
    • pp.119-128
    • /
    • 2021
  • This study defines the integrated game experience of game users that across internal and external media of game as the transmedia enjoyment of game. This study categorizes the cases and analyze features. Game users have four types of transmedial enjoyment. The expansion type is characterized by the user's desire to solve the uncertainty, and the transmission type is characterized by the emergence of alternative play spaces. In the permeation type and the circulation type, it is observed users participate more in the content can be re-contextualized and based on real world knowledge.

Biodegradative Activities of Fungal Strains Isolated from Terrestrial Environments in Korea

  • Lee, Seung-Yeol;Ten, Leonid N.;Das, Kallol;You, Young-Hyun;Jung, Hee-Young
    • Mycobiology
    • /
    • v.49 no.3
    • /
    • pp.285-293
    • /
    • 2021
  • Polylactic acid (PLA) and polycaprolactone (PCL) are commercially available bioplastics that are exploited worldwide, and both are biodegradable. The PLA and PCL polymer-degrading activity of 30 fungal strains that were isolated from terrestrial environments were screened based on the formation of a clear zone around fungal colonies on agar plates containing emulsified PLA or PCL. Among them, five strains yielded positive results of biodegradation. Strains Korean Agricultural Culture Collection (KACC) 83034BP and KNUF-20-PPH03 exhibited PCL degradation; two other strains, KACC 83035BP and KNUF-20-PDG05, degraded PLA; and the fifth strain, KACC 83036BP, biodegraded both tested plastics. Based on phylogenetic analyses using various combinations of the sequences of internal transcribed spacer (ITS) regions, RPB2, LSU, CAL, and b-TUB genes, the above-mentioned strains were identified as Apiotrichum porosum, Penicillium samsonianum, Talaromyces pinophilus, Purpureocillium lilacinum, and Fusicolla acetilerea, respectively. Based on our knowledge, this is the first report on (i) plastic biodegraders among Apiotrichum and Fusicolla species, (ii) the capability of T. pinophilus to degrade biodegradable plastics, (iii) the biodegradative activity of P. samsonianum against PCL, and (iv) the accurate identification of P. lilacinum as a PLA biodegrader. Further studies should be conducted to determine how the fungal species can be utilized in Korea.

Trend of Clinical Studies on Herbal Medicine Treatment for Night Terrors (야경증의 한약 치료에 대한 임상연구 동향)

  • Jeong, Jieun;Choi, Yoomin;Jang, Insoo;Jeong, Minjeong
    • The Journal of Pediatrics of Korean Medicine
    • /
    • v.36 no.1
    • /
    • pp.78-90
    • /
    • 2022
  • Objectives The purpose of this study is to review relevant clinical studies to investigate the effectiveness of herbal medicines for night terror in children. Methods Studies on herbal treatment for night terrors were searched and analyzed through electronic databases such as PubMed, China National Knowledge Infrastructure, Wanfang, CiNii, J-STAGE, Oriental Medicine Advanced Searching Integrated System and Science ON. Studies included Randomized controlled trials, case series, and case reports. Results A total of 25 studies were selected and analyzed. In most studies, improvement of night terrors was observed after treatment, such as high total effectiveness. In one study, the frequency of night terrors was decreased significantly in herbal medicine group. Conclusions Based on the results of the clinical studies, we identified that herbal medicine is an effective treatment for night terror. But it is considered necessary to prove the effect and safety through additional systematic clinical studies.

Morphological and molecular characterization of the genus Coolia (Dinophyceae) from Bahía de La Paz, southwest Gulf of California

  • Morquecho, Lourdes;Garate-Lizarraga, Ismael;Gu, Haifeng
    • ALGAE
    • /
    • v.37 no.3
    • /
    • pp.185-204
    • /
    • 2022
  • The genus Coolia A. Meunier 1919 has a global distribution and is a common member of epiphytic dinoflagellate assemblages in neritic ecosystems. Coolia monotis is the type species of the genus and was the only known species for 76 years. Over the past few decades, molecular characterization has unveiled two species complexes that group morphologically very similar species, so their limits are often unclear. To provide new knowledge on the biogeography and species composition of the genus Coolia, 16 strains were isolated from Bahía de La Paz, Gulf of California. The species were identified by applying morphological and molecular approaches. The morphometric characteristics of all isolated Coolia species were consistent with the original taxa descriptions. Phylogenetic analyses (large subunit [LSU] rDNA D1 / D2 and internal transcribed spacer [ITS] 1 / 5.8S / ITS2) revealed a species assemblage comprising Coolia malayensis, C. palmyrensis, C. tropicalis, and the C. cf. canariensis lineage. This is the first report of Coolia palmyrensis and C. cf. canariensis in Mexico and C. tropicalis in the Gulf of California. Our results strengthen the biogeographical understanding of these potentially harmful epiphytic dinoflagellate species.

Development of a Professionalism Measurement Scale for Clinical Nurses (임상간호사의 전문성 측정도구 개발)

  • Kim, Jeonghyun;Lee, Hyesoon;Pang, Yanghee
    • Journal of Korean Clinical Nursing Research
    • /
    • v.29 no.2
    • /
    • pp.186-197
    • /
    • 2023
  • Purpose: The purpose of this study was to develop a scale to measure professionalism of clinical nurses and evaluate the reliability and validity of the scale. Methods: DeVellis's scale-development eight steps were applied. The initial items were developed through a literature review and discussion with investigators, and the content validity was verified by seven experts. The data were collected from 250 hospital nurses for exploratory factor analysis and 217 hospital nurses for confirmatory factor analysis. Exploratory and confirmatory factor analyses were utilized to assess the construct validity. Cronbach's ⍺ was used to test the internal consistency reliability. Results: The results of the exploratory and confirmatory factor analyses showed that the scale comprised four factors: professional skill(eight items), sense of ethics (five items), knowledge-seeking activities (four items), and autonomy(three items). The four-factor structure was validated (x 2 =600.85 p<.001, GFI=.88, CFI=.84, RMSEA=.07), and Cronbach's ⍺ for the total scale was .84. Conclusion: The study results showed satisfactory reliability and validity of the professionalism measurement scale for clinical nurses. This scale has potential as an appropriate instrument for measuring clinical nurse professionalism.

Morphological and Phylogenetic Analysis of a New Record of Paraconiothyrium kelleni from Soil in Korea

  • Mukesh Kumar Yadav;Kallol Das;Jung-Joo Ryu;Seong-Keun Lim;Jin-Sil Choi;Seung-Yeol Lee;Hee-Young Jung
    • The Korean Journal of Mycology
    • /
    • v.51 no.2
    • /
    • pp.101-109
    • /
    • 2023
  • A fungal strain designated KNUF-21-66Q1 was isolated from soil in Chungcheongbuk Province, Korea. Moderate growth of colonies was observed on potato dextrose agar, oatmeal agar (OA), malt extract agar, and cornmeal agar media at 25℃, and the detailed morphology was examined on OA medium. The colonies on OA medium were flat, had entire margin, hyaline, and yellow concentric rings in 3-4 weeks. Conidiomata were pycnidial, solitary or clustered, globose to subglobose, black-brown, and 300-500 ㎛ in diameter. Conidiogenous cells were smooth, hyaline, globose to ampulliform, and 6.0-9.0×3.0-6.0 ㎛ in size (n=15). Conidia were hyaline to pale brown, slightly golden, obovoid to slightly ellipsoidal, smooth, guttulate, and 3.0-4.7×2.1-3.3 ㎛ in size (n=100). The strain was confirmed based on phylogenetic analysis using internal transcribed spacer regions, the partial 28S rDNA of large subunit, and β-tubulin gene sequences. The morphological observations and phylogenetic analysis revealed that the strain KNUF-21-66Q1 was similar to the previously described Paraconiothyrium kelleni. To our knowledge, this is the first report of P. kelleni in Korea.

First Report of an Apple Ring Rot Fungus Botryosphaeria kuwatsukai in Korea

  • Gwang-Jae Lim;Kallol Das;Hyeong-Jin Noh;Seong-Keun Lim;Young-Je Cho;Seung-Yeol Lee;Hee-Young Jung;Seong Hwan Kim
    • The Korean Journal of Mycology
    • /
    • v.51 no.2
    • /
    • pp.111-120
    • /
    • 2023
  • Three fungal strains designated as KNUF-23-MG32, KNUF-23-YC8, and KNUF-23-MJ82 were isolated from the abnormal symptomatic apple trees during screening fungal pathogens collected in Jeollanam-do and Gyeongsangbuk-do, Korea. These fungal strains were found to have similar cultural and morphological characteristics close to the genus Botryosphaeria. Morphological characteristics were matched with B. kuwatsukai CBS 135219 but different with B. dothidea KACC 45481 and B. sinensis HMAS 246714T. Pathogenicity tests of strain KNUF-23-MG32 showed that this strain causes rot in Fuji apples. Molecular phylogenetic analysis based on the sequences of the internal transcribed spacer (ITS) regions, translation elongation factor 1-alpha (TEF1α), and partial β-tubulin (TUB2) showed that these strains are B. kuwatsukai. To the best of our knowledge, this is the first report of an apple ring rot fungus Botryosphaeria kuwatsukai in Korea.

Characterization of Three Fusarium spp. Causing Wilt Disease of Cannabis sativa L. in Korea

  • Young Mo Koo;S. M. Ahsan;Hyong Woo Choi
    • Mycobiology
    • /
    • v.51 no.3
    • /
    • pp.186-194
    • /
    • 2023
  • In July 2021, wilting symptoms were observed in adult and seedling hemp (Cannabis sativa L. cv. Cherry Blossom) plants grown in a greenhouse. As the disease progressed, yellowing and wilting symptoms on the leaves developed, resulting in whole plant death. In seedling plants, typical damping-off symptoms were observed. To identify the pathogen, the roots of diseased plants were sampled, surface sterilized, and cultured on potato dextrose agar (PDA) media. From the culture, 4 different fungal isolates were recovered and purely cultured. Each fungal isolate showed distinct growth shapes and color development on malt extract agar, oatmeal agar, sabouraud dextrose agar, and PDA media. Microscopic observation and molecular identification using ribosomal DNA internal transcribed spacer sequencing identified them as 3 Fusarium spp. and 1 Thielaviopsis paradoxa. Additional sequencing of elongation factor 1-alpha and b-tubulin regions of 3 Fusarium spp. revealed that 2 of them are Fusarium solani, and the other one is Fusarium proliferatum. To examine which isolate can act as a causal agent of wilt disease of hemp, each isolate was tested for their pathogenicity. In the pathogenicity test, F. solani AMCF1 and AMCF2, and F. proliferatum AMCF3, but not T. paradoxa AMCF4, were able to cause wilting disease in hemp seedlings. Therefore, we report that F. solani AMCF1 and AMCF2, and F. proliferatum AMCF3 as causal agents of Fusarium wilt of hemp plants. To our knowledge, this is the first report of the wilt disease of C. sativa L. caused by Fusarium spp. in Korea.

Molecular and Morphological Characterization of Three New Fungal Species of the Class Sordariomycetes from Korea

  • Kallol Das;Jae-Ho Ban;So-Young Choi;Seung-Yeol Lee;Hee-Young Jung
    • The Korean Journal of Mycology
    • /
    • v.51 no.1
    • /
    • pp.25-38
    • /
    • 2023
  • Three fungal strains belonging to the class Sordariomycetes were isolated from soil collected on Jeju Island and Gyeongsangbuk-do, Korea. They were identified as Diaporthe endophytica (KNU-JJ-1809), Faurelina indica (KNU-JJ-1830), and Trichoderma ivoriense (KNU-4-KH1). KNU-JJ-1809 produced beta conidia that were straight, curved, hyaline, smooth-walled, with a diameter of 16.5-25.0×0.6-1.7 ㎛. The conidia of strain KNU-JJ-1830 were hyaline to light green, thin, clavate, round, truncate base, had guttules at both ends, with a diameter of 2.5-5.2×1.7-3.8 ㎛. The conidia of strain KNU-4-KH1 were oblong or ellipsoidal, smooth-walled, greenish, with a diameter of 2.2-4.4×2.2-3.6 ㎛. Internal transcribed spacer regions, partial large subunit, translation elongation factor 1-alpha, β-tubulin, and calmodulin genes were used to confirm the strains, and their cultural and morphological characteristics. To our knowledge, this is the first report on D. endophytica, F. indica, and T. ivoriense in Korea.