• Journal of Life Science
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• v.19 no.11
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• pp.1506-1513
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• 2009

RGS proteins have been identified as negative regulators of G protein signalling pathways and attenuate the activity of GPCR receptors. However, information on the regulatory effects of RGS proteins in the activity of cannabinoid receptors is limited. In this study, the role of RGS proteins on the signal transduction of the CB2 cannabinoid receptor was investigated in HEK293 cells co-transfected with CB2-receptors and plasmids encoding RGS2, RGS3, RGS4 and RGS5. Treatment of cells with WIN55, 212-2, a CB2 receptor agonist, inhibited forskolin-induced cAMP response element (CRE) activity in CB2-transfected HEK293 (CB2-HEK293) cells. This inhibitory effect of WIN 55, 212-2 on CRE activity was reversed by co-transfection of CB2-HEK293 cells with RGS3, but not with RGS2, RGS4 and RGS5. However, endogenous RGS3 protein knocked down by a small interfering siRNA targeting RGS3 gene enhanced inhibition of forskolin induced CRE activity via agonist induced CB2 receptor signal transduction. These results indicate the functional role of endogenous RGS protein in cannabinoid signaling pathways and define receptor-selective roles of endogenous RGS3 in modulating CRE transcriptional responses to agonist induced CB2 receptor activity.

• Journal of the Korean Institute of Gas
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• v.20 no.4
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• pp.65-77
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• 2016

Modeling for complex reacting flow in Fischer-Tropsch reactor is one of the challenges in the field of Computational Fluid Dynamics (CFD). It is hard to derive each and every reaction rate for all chemical species because Fisher-Tropsch reaction produces many kinds of hydrocarbons which include lots of isomers. To overcome this problem, after analyzing the existing methodologies for reaction rate modeling, non-Anderson-Schulz-Flory methodology is selected to model the detailed reaction rates. In addition, the inside flow has feature of multi-phase flow, and the methodologies for modeling multi-phase flow depend on the interference between the phases, distribution of the dispersed phase, flow pattern, etc. However, existing studies have used a variety of inside flow modeling methodologies with no basis or rationale for the feasibility. Modeling inside flow based on the experimental observation of the flow would be the best way, however, with limited resources we infer the probable regime of inside flow based on conventional fluid dynamics theory; select the appropriate methodology of Mixture model; and perform systematic CFD modeling. The model presented in this study is validated through comparisons between experimental data and simulation results for 10 experimental conditions.

• The Journal of the Korea institute of electronic communication sciences
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• v.3 no.3
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• pp.188-194
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• 2008

In this paper, we propose for improving QoS in Hospital wireless network using Cellular-IP/PRC(Paging Route Cache) with Paging Cache and Route Cache in Cellular-IP and propose for performance of realtime and non-real time handoff service using Handoff state machine Paging Route Cache. Although the Cellular-IP/PRC technology is devised for mobile internet communication, it has its vulnerability in frequent handoff environment. This handoff state machine using differentiated handoff improves quality of services in Cellular-IP/PRC Suggested algorithm shows better performance than existing technology in wireless mobile internet communication environment. When speech quality is secured considering increment of interference to receive in case of suppose that proposed acceptance method grooves base radio station capacity of transfer node is plenty, and moat of contiguity cell transfer node was accepted at groove base radio station with a blow, groove base radio station new trench lake acceptance method based on transmission of a message electric power estimate of transfer node be. Do it so that may apply composing PC(Paging Cache) and RC(Routing Cache) that was used to manage paging and router in radio Internet network in integral management and all nodes as one PRC(Paging Router Cache), and add hand off state machine in transfer node so that can manage hand off of transfer node and Roaming state efficiently, and studies so that achieve connection function at node. Analyze benevolent person who influence on telephone traffic in system environment and forecasts each link currency rank and imbalance degree, forecast most close and important lake interception probability and lake falling off probability, GoS(Grade of Service), efficiency of cell capacity in QoS because applies algorithm proposing based on algorithm use gun send-receive electric power that judge by looking downward link whether currency book was limited and accepts or intercept lake and handles and displays QoS performance improvement.

• Journal of Navigation and Port Research
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• v.39 no.4
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• pp.293-297
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• 2015

Underwater acoustic communications has been limited use for military purposes in the past. However, the fields of underwater applications expend to detection, submarine and communication in recent. The excessive multipath encountered in underwater acoustic communication channel is creating inter symbol interference, which is limiting factor to achieve a high data rate and bit error rate performance. To improve the performance of a received signal in underwater communication, many researchers have been studied for channel coding scheme with excellent performance at low SNR. In this paper, we applied BCJR decoder based ( 2,1,7 ) convolution codes and to compensate for the distorted data induced by the multipath, we applying the turbo equalization method. Through the underwater experiment on the Gyeungcheun lake located in Mungyeng city, we confirmed that turbo equalization structure of BCJR has better performance than hard decision and soft decision of Viterbi decoding. We also confirmed that the error rate of decoder input is less than error rate of $10^{-1}$, all the data is decoded. We achieved sucess rate of 83% through the experiment.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.6
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• pp.638-644
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• 2018

Relay systems have recently gained attentions because of its capability of cell coverage extension and the power gain as the one of key technologies for 5G. Relays can be exploited for small-cell base stations and the autonomous network, where communication devices communicate with each other cooperatively. Therefore, the relay technology is expected to enable the low power and large capacity communication. In order to maximize the benefits of using a limited number of relays, the efficient relay selection method is required. Especially, when two nodes exchange their data with each other via relay, the relay selection can maximize the average data rate by the spatial location of the relay. For this purpose, the average data rate is analyzed first according to the relay selection. In this paper, we analyzed the average data rate when two nodes exchange their data via dual-hop decode and forward relaying considering the interference by the concurrent transmission under Nakagami-m fading channel. The correctness of the analysis is verified by the Monte Carlo simulation. The results show that the concurrent transmission is superior to the non-concurrent transmission in the high required data rate region rather than in the low required data rate region.

• KIPS Transactions on Computer and Communication Systems
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• v.10 no.8
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• pp.215-222
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• 2021

In order to alleviate the limited resource problem and interference problem in cellular networks, the dual connectivity technology has been introduced with the cooperation of small cell base stations. In this paper, we design a new efficient and fair resource allocation scheme for the dual connectivity technology. Based on two different bargaining solutions - Generalizing Tempered Aspiration bargaining solution and Gupta and Livne bargaining solution, we develop a two-stage radio resource allocation method. At the first stage, radio resource is divided into two groups, such as real-time and non-real-time data services, by using the Generalizing Tempered Aspiration bargaining solution. At the second stage, the minimum request processing speeds for users in both groups are guaranteed by using the Gupta and Livne bargaining solution. These two-step approach can allocate the 5G radio resource sequentially while maximizing the network system performance. Finally, the performance evaluation confirms that the proposed scheme can get a better performance than other existing protocols in terms of overall system throughput, fairness, and communication failure rate according to an increase in service requests.

• Journal of Popular Narrative
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• v.26 no.3
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• pp.87-120
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• 2020

The study noted the characteristics of the web novel's 'Book Travel' motif, which reflects the characteristics of popular culture content, which is free to use familiar genre grammar or code. The imagination of the main character entering the work he read in the real world is a reinterpretation of the existing genre grammar of the web novel, and studying the motif is meaningful in reviewing the intertext of the genre. This motif, summarized as 'Book Travel' differs from other genres in the romance fantasy genre, which can also be used to reveal the gender characteristics of the genre. The study noted that the 'Book Travel' motif was born from an interactive interpretation of existing narratives, thus having a affinity with dimensional shift, regression, and alternative historical objects, and referring to the writing norms of Fanfiction. Through this, it was predicted that the re-combination of existing narratives and interference between genres would continue in the future. Next, the original move in the romance fantasy genre was seen as quite conservative and revealing the logic of self-improvement even though people around him became the main characters and overthrew the narrative. The characters should use their knowledge of the future of the real world to fight in a world of survival where destruction has been predicted. The appearance of an ethical and self-help subject is interesting, but on the other hand, I could look at conservatism in that romance is a way of survival and achievement of characters. The research is meaningful in that it reviewed the characteristics of the original transfer motif, which started fairly quickly in the romance fantasy genre, and reviewed its appearance background and characteristics. There was a limit to the collection of physical works and limited platform. The above limits are intended to be supplemented by further reviewing and supplementing later works.

• Journal of Space Technology and Applications
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• v.2 no.1
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• pp.41-51
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• 2022

CubeSat is a satellite platform that is widely used not only for earth observation but also for space exploration. CubeSat is also used in magnetic field investigation missions to observe space physics phenomena with various shape configurations of magnetometer instrument unit. In case of magnetic field measurement, the magnetometer instrument should be far away from the satellite body to minimize the magnetic disturbances from satellites. But the accommodation setting of the magnetometer instrument is limited due to the volume constraint of small satellites like a CubeSat. In this paper, we investigated that the magnetic field interference generated by the cube satellite was analyzed how much it can affect the reliability of magnetic field measurement. For this analysis, we used a reaction wheel and Torque rods which have relatively high-power consumption as major noise sources. The magnetic dipole moment of these parts was derived by the data sheet of the manufacturer. We have been confirmed that the effect of the residual moment of the magnetic torque located in the middle of the 3U cube satellite can reach 36,000 nT from the outermost end of the body of the CubeSat in a space without an external magnetic field. In the case of accurate magnetic field measurements of less than 1 nT, we found that the magnetometer should be at least 0.6 m away from the CubeSat body. We expect that this analysis method will be an important role of a magnetic cleanliness analysis when designing a CubeSat to carry out a magnetic field measurement.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.5
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• pp.737-746
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• 2023

As the core infrastructure to lead technical innovation for the fourth industrial revolution, economic value and utilizations of radiowaves are increased rapidly. The objectives of this study are to recognize the growing trend of radio stations that transmit information using radiowaves, a limited resource of the country, and to propose developed plans for the radio stations operation system in line with the changing radio technology and use environment. To be specific, the detailed implementation procedures and methods of the system were derived in accordance with the government's plan to convert the complete inspection of radio stations into a SDoC(Self Declaration of Conformity) by the telco. SDoC is a policy that grants autonomy and responsibility for radio waves interference management to existing telecom operator recognized as having radio stations operating capabilities. It has significance in that the function of radio stations inspection, which is a representative technical regulation, is efficiently distributed to the government and the private sector. This study has significance in providing reference for expediting deregulation in the radiowaves management policy.

• Animal Bioscience
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• v.37 no.5
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• pp.929-943
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• 2024

Objective: The present study was executed to explore the molecular mechanism of fibroblast growth factor 10 (FGF10) gene in bovine adipogenesis. Methods: The bovine FGF10 gene was overexpressed through Ad-FGF10 or inhibited through siFGF10 and their negative control (NC) in bovine adipocytes, and the multiplicity of infection, transfection efficiency, interference efficiency were evaluated through quantitative real-time polymerase chain reaction, western blotting and fluorescence microscopy. The lipid droplets, triglycerides (TG) content and the expression levels of adipogenic marker genes were measured during preadipocytes differentiation. The differentially expressed genes were explored through deep RNA sequencing. Results: The highest mRNA level was found in omasum, subcutaneous fat, and intramuscular fat. Moreover, the highest mRNA level was found in adipocytes at day 4 of differentiation. The results of red-oil o staining showed that overexpression (Ad-FGF10) of the FGF10 gene significantly (p<0.05) reduced the lipid droplets and TG content, and their down-regulation (siFGF10) increased the measurement of lipid droplets and TG in differentiated bovine adipocytes. Furthermore, the overexpression of the FGF10 gene down regulated the mRNA levels of adipogenic marker genes such as CCAAT enhancer binding protein alpha (C/EBPα), fatty acid binding protein (FABP4), peroxisome proliferator-activated receptor-γ (PPARγ), lipoprotein lipase (LPL), and Fas cell surface death receptor (FAS), similarly, down-regulation of the FGF10 gene enriched the mRNA levels of C/EBPα, PPARγ, FABP4, and LPL genes (p<0.01). Additionally, the protein levels of PPARγ and FABP4 were reduced (p<0.05) in adipocytes infected with Ad-FGF10 gene and enriched in adipocytes transfected with siFGF10. Moreover, a total of 1,774 differentially expressed genes (DEGs) including 157 up regulated and 1,617 down regulated genes were explored in adipocytes infected with Ad-FGF10 or Ad-NC through deep RNA-sequencing. The top Kyoto encyclopedia of genes and genomes pathways regulated through DEGs were the PPAR signaling pathway, cell cycle, base excision repair, DNA replication, apoptosis, and regulation of lipolysis in adipocytes. Conclusion: Therefore, we can conclude that the FGF10 gene is a negative regulator of bovine adipogenesis and could be used as a candidate gene in marker-assisted selection.