• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.17 no.4 s.107
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• pp.358-367
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• 2006

In this paper, a mathematical formulation of protection ratio and its calculation method are suggested for a radio relay system with diversity techniques. The analysis of protection ratio and its physical meaning have been performed for the space or frequency diversity system, and in particular protection ratios are reviewed in terms of the parameters of diversity improvement factor, which comprises antenna gain, separation distance between antennas, frequency and its difference between carriers, and distance. As one of simulated results, the co-channel protection ratio of 60 dB is obtained for the space diversity system regarding 6.2 GHz, 60 km, 64-QAM, and 25 m between antennas, which gives 15 dB less than the co-channel protection ratio of the non-space diversity system. In addition, the co-channel protection ratio for the frequency diversity system gives 64 dB in case of frequency offset of 0.5 GHz under the same conditions as the space diversity system, which brings about 11 dB less than the co-channel protection ratio of non-frequency diversity system. In consequency, it is interesting to note that the space diversity system is less sensitive to interference in comparison to the frequency diversity system and provides better quality of service for a given interference.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.05a
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• pp.685-688
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• 2016

SBAS(Satellite Based Augmentation System) broadcasts the correction message based on satellite communication to improve the positioning accuracy of GNSS user. For this reason, SBAS is actively being utilized on navigation part. To apply SBAS to navigation part, it should satisfy not only accuracy but also integrity, continuity, availability, coverage requirements and so on. Since SBAS reference station is the base infrastructure of SBAS, it is the main factor to determine the environment, position, and geometry of reference stations to achieve SBAS service performance. Therefore, a site environmental analysis should be performed prior to the selection of SBAS reference station. In this paper, it performs the environmental analysis of NDGPS(Nationwide Differential GPS) reference station sites on the premise that SBAS reference station will be co-operated in the same site of NDGPS operated by MOF(Ministry of Oceans and Fisheries). The environmental analysis is conducted as carrying out the visibility analysis of GPS satellite and interference analysis. This paper also presents the brief procedures and requirements for site survey of SBAS reference station.

• Korean Journal of Mineralogy and Petrology
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• v.35 no.4
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• pp.507-520
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• 2022

The Sr isotope ratio, which is used as basic data for rock formation time, crustal and mantle evolution studies, is determined by mass spectrometer such as thermal ionization mass spectrometry (TIMS) or multi-detector inductively coupled plasma mass spectrometry (MC-ICP-MS). In this technical report, we compared how incomplete chemical separation of elements affects the determination of Sr isotope ratios. For the experiment, commercial resin, NBS987(NIST SRM987) Sr isotope standard, and rock standard samples from the Geological Survey of Japan (GSJ) such as JG1a, JB3 and JA1 were used. As a result of the comparative experiment, it was clearly observed that the measured values of ⁸⁷Sr/⁸⁶Sr change when Rb remains due to incomplete separation of the NBS987 Sr isotope standard sample as well as the rock standard samples of GSJ. This indicates that complete separation is an important factor since the calculated value deviates from the true value even though correction for isotope interference by isobar is performed when measuring the isotope ratio with MC-ICP-MS. This also suggests that, when reporting the measurement result of Sr isotope ratio using MC-ICP-MS, the measurement strength of ⁸⁵Rb should be reported together with the measurement strength of all isotopes of Sr so that isotope interference by isobar can be judged.

• Journal of the Korean Geotechnical Society
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• v.24 no.9
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• pp.13-21
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• 2008

Partitioning tracer method is a useful tool to characterize large domains of the aquifers contaminated with light nonaqueous phase liquids (LNAPLs). Sorption of the partitioning tracers to the organic matter content of soil can potentially influence the efficacy of partitioning tracer method. LNAPL-water partitioning coefficients of tracers ($K_{nw}$), measured by static method, showed linear relationship. Sorption isotherm tests were conducted to evaluate the sorption capacity of the soils packed in the columns and the results were appropriately represented by Freundlich sorption isotherm. The sorption of tracers proportionally increased with the increase of the organic matter content of the soil. Laboratory experiments were conducted in four columns each packed with soils of different organic matter contents to determine the potential interference effects of sorption to soil organic matter content and correction factors for the errors in estimation of LNAPLs by partitioning tracer method. Though there were no contaminants added, breakthrough curves from columns packed with mixture of Jumunjin standard sand and organic matter showed separation of tracers. Columns were then contaminated to residual saturation with kerosene and breakthrough curves were obtained. The results show that sorption of tracers to soil organic matter leads to an increase in the retardation factor (R) and hence, to an overestimation of the saturation of LNAPLs. A relation between the percentage of organic matter content and the corresponding percentage error in the estimation of NAPLs has been developed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2753-2758
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• 2014

Background: GC-binding factor 2 (GCF2) is a transcriptional regulator that represses transcriptional activity of the epidermal growth factor receptor (EGFR) by binding to a specific GC-rich sequence in the EGFR gene promoter. In addition to this function, GCF2 has also been identified as a tumor-associated antigen and regarded as a potentially valuable serum biomarker for early human hepatocellular carcinoma (HCC) diagnosis. GCF2 is high expressed in most HCC tissues and cell lines including HepG2. This study focused on the influence of GCF2 on cell proliferation and apoptosis in HepG2 cells. Materials and Methods: GCF2 expression at both mRNA and protein levels in HepG2 cells was detected with reverse transcription (RT) PCR and Western blotting, respectively. RNA interference (RNAi) technology was used to knock down GCF2 mRNA and protein expression. Afterwards, cell viability was analyzed with a Cell Counting Kit-8 (CCK-8), and cell apoptosis and caspase 3 activity by flow cytometry and with a Caspase 3 Activity Kit, respectively. Results: Specific down-regulation of GCF2 expression caused cell growth inhibition, and increased apoptosis and caspase 3 activity in HepG2 cells. Conclusions: These primary results suggest that GCF2 may influence cell proliferation and apoptosis in HepG2 cells, and also provides a molecular basis for further investigation into the possible mechanism at proliferation and apoptosis in HCC.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.640-647
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• 2016

By minimizing fluorescence interference phenomena, aequorin-based luminescence technology can provide a relatively sensitive detection platform with integration of $G{\alpha}16$ protein in order to track internal calcium mobilization by G protein-coupled receptors (GPCR). In this type of cell-based functional assay format, it is essential to optimize the transfection process of a receptor and $G{\alpha}16$ protein. For this study, corticotropin releasing factor receptor subtype 2(CRF2) was set as a model system to generate three stable cells with CRF2 and $G{\alpha}16$ in addition to transiently transfected cells under three different conditions. Agonist (sauvagine) and antagonist (K41498) responses in those cells were analyzed to develop the optimum transfection process. As a result, the effective signal ratio in the dose response experiments of sauvagine and K41498 were at least 10-fold higher (z'=0.77) in CRF2-$G{\alpha}16$ stable cells. For the transient transfection cells, stable expression of $G{\alpha}16$ prior to the CRF2 represented a two-fold higher signal (z'=0.84) than the other cases of transient transfection. In conclusion, for the utilization of transient transfection processes to develop a cell-based GPCR functional assay system, it is suggested to introduce various target receptors after stable expression of $G{\alpha}16$ protein.

• Journal of the Korean Magnetics Society
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• v.15 no.5
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• pp.282-286
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• 2005

Ni-Cu-Zn ferrites were prepared by the co-precipitation and ferrite microwave absorbers on low temperature sintering were investigated in this work. The properties of its microwave absorbing and physical were analyzed into variations of Ni addition, calcination temperature, sintering temperature. From the analysis of X-ray diffraction patterns, we can see that all the particles have only a single phase spinel structure. In addition, the powders particle size distribution obtained the nano size. By increasing the Ni additive, the permeability of the powders was decreased and the loss factor increased at sintering temperature $1100^{\circ}C$. Also, we considered that it can used high frequency rage. We found that the $(Ni_{0.7}Cu_{0.2}Zn_{0.1}O)_{1.02}(Fe_{2}O_3)_{0.98}$ appeared microwave absorbing properties better than other composition.

• BMB Reports
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• v.46 no.5
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• pp.252-257
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• 2013

Fibroblast activation protein (FAP) is a specific serine protease expressed in tumor stroma proven to be a stimulatory factor in the progression of some cancers. The purpose of this study was to investigate the effects of FAP knockdown on tumor growth and the tumor microenvironment. Mice bearing 4T1 subcutaneous tumors were treated with liposome-shRNA complexes targeting FAP. Tumor volumes and weights were monitored, and FAP, collagen, microvessel density (MVD), and apoptosis were measured. Our studies showed that shRNA targeting of FAP in murine breast cancer reduces FAP expression, inhibits tumor growth, promotes collagen accumulation (38%), and suppresses angiogenesis (71.7%), as well as promoting apoptosis (by threefold). We suggest that FAP plays a role in tumor growth and in altering the tumor microenvironment. Targeting FAP may therefore represent a supplementary therapy for breast cancer.

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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• v.5 no.1
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• pp.22-30
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• 1994

The error probability of the DS-CDMA / DPSK cellular mobile communication system with CCI canceller and MRC diversity reception technique has been analyzed in the cellular radio channel which is characterized by AWGN, Multi-User Interference(MUI) and m-distribution fading. System capacity i. e., number of user per cell has been derived and the evaluated results are shown in figures as a function of PN code sequence length, fading index, BER, number of diversity branches and $E_b/N_o$, Here, the voice activity factor is assumed to be 3/8, the number of sectors in a cell 3 and Multi-User Iner- ference is modeled as Gaussian process.

• Journal of Environmental Impact Assessment
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• v.17 no.3
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• pp.177-188
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• 2008

Attempts to develope designation criteria for ecological protected areas were made for rational and scientific designation and management of 'ecosystem and landscape conservation areas', 'wetland protection areas', 'special islands protection areas', and 'wildlife protected areas' which have been designated and managed by the Ministry of Environment. Through analysis of the requisites and criteria of IUCN, UNESCO, Natura 2000, the Ramsar convention, the United States, the United Kingdom, Japan, and Germany as well as various academic researches, evaluation items of the protected areas were classified into naturalness, biodiversity, ecosystem, and scientific values. These classification titles are reflection of Korean laws concerning the 4 protected areas described above. Of these items 'naturalness' is composed of 3 factors of wilderness, geomorphology and landscape, and vegetation. 'Biodiversity' is composed of the 5 factors of species diversity, endangered species, rare species, indigenous biological resources, and habitat of wetland wild animals. 'Ecosystem' is composed of 5 factors of typicalness, diversity, rarity, restoration ability, and degree of interference. All factors are scored using a 3 point scale of high, middle, or low and are then transformed into the numerical index for designating and zoning purposes. Conclusively, it is expected that the developed methodology will be highly applicable with field verifications.