• The Korean Journal of Physiology and Pharmacology
• /
• v.12 no.4
• /
• pp.143-148
• /
• 2008

Caveolin-1 (CAV1) is an integral membrane protein that may function as a scaffold for plasma membrane proteins and acts as a tumor suppressor protein. One causative factor of chemotherapy-resistant cancers is P-plycoprotein (P-gp), the product of the multidrug resistance-1 gene (MDR1), which is localized in the caveolar structure. Currently, the interactive roles of CAV1 and MDR1 expression in the death of cancer cells remain controversial. In this study, we investigated the effects of indomethacin on the cell viability and the expression levels of MDR1 mRNA and protein in a CAV1-siRNA-mediated gene knockdown hepatoma cell line (SK-Hep1). Cell viability was significantly decreased in CAV1-siRNA-transfected cells compared with that of control-siRNA-transfected cells. Furthermore, the viability of cells pretreated with CAV1 siRNA was markedly decreased by treatment with indomethacin (400${\mu}$M for 24 h). However, the protein and mRNA levels of MDR1 were unchanged in CAV1-siRNA-transfected cells. These results suggest that CAV1 plays an important role as a major survival enzyme in cancer cells, and indomethacin can sensitively induce cell death under conditions of reduced CAV1 expression, independent of MDR1 expression.

• International Commerce and Information Review
• /
• v.15 no.2
• /
• pp.71-82
• /
• 2013

The automotive supply chain is increasingly complex as automakers seek more profitable solutions with global out-sourcing and manufacturing strategies. In the automotive industry, using returnable plastic containers (RPCs) is very common for domestic operations, but for internationally, it has not been considered by many companies because of issues such as overall distance and difficulty of control. The results of this simulation can help to analyze the interactive and coherent behavior of packaging and supply chain systems. The data obtained from the model can be applied to make substantial decisions for choosing the most profitable packaging types, at the same time as it can lead to designing an optimum supply chain for RPCs used in international supply chains.

• Journal of Korean Home Economics Education Association
• /
• v.17 no.3 s.37
• /
• pp.109-121
• /
• 2005

The Purpose of this research was to find out differences in motivation and achievement by gender between traditional group and ARCS group. The subjects were 217 first graders in six different classes from a middle school in Daegu. Each Class had Five lessons during 5 weeks. The collected data were analyzed using descriptive statistics, ANOVA and ANCOVA by SPSS 10.0 program. The results of this study are as follows : First, the ARCS group showed significantly higher score than the control group in motivation. But no significant difference was found between boys and girls and in interactive effects. Statistically significant differences were found in three factors of motivation - attention, relevance and satisfaction - from the ARCS model, but no significant difference in confidence. Second, there was no significant difference in students' achievement.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.12 no.1
• /
• pp.163-172
• /
• 2017

This study is a system that provides a suitable level of the problem, designing the learner certification simulation program based on the ITS(: Intelligent Tutoring System) based on the model and the learning expert model, the model through a buggy (Buggy Model). In the demand survey that reflects the needs of users, convenience, effectiveness, scalability, and reliability were required. In order to reflect this, various problems were developed, problem type analysis, difficulty control, student grades and level management. Users who are preparing for the certification test are expected to use the development system to solve the problems according to their own level and to solve various types of problems in a practical environment to greatly shorten the preparation period for certification.

• Biomedical Science Letters
• /
• v.10 no.4
• /
• pp.515-521
• /
• 2004

To measure regional cerebral blood volume (rCBV) with perfusion MR imaging of cerebral fat embolism by neutral fat and free fatty acids in cats. Triolein (group 1, n=15), oleic acid (group 2, n=9) and linoleic acid (group 3, n=11) were infused into unilateral internal carotid artery using microcatheter through the transfemoral approach. PVA particle was used as a non-fat embolic material in a control group (group 4, n=9). Perfusion-weighted MR image was obtained at 30 minutes and 2 hours postembolization, based on T2-and diffusion-weighted images. The data of lesion and contralateral normal area were transferred to personal computer, time-to-signal intensity curve was drawn and trans for used to △R2/sup */ curve in regular order. The process in the personal computer was done by using the author's developmental image processing program and interactive data language (IDL) softwares. Statistical significance was approved by paired t-test and ANOVA. rCBV of the lesion was decreased comparing to the normal area in all groups. The ratios of rCBV were as follows (group No, at 30 minutes, at 2 hours); group 1,32％, 51％; group 2, 30％, 44％; group 3, 39％, 61％; group 4, 21％, 36％. rCBVs of 2 hours was significantly increased compared to those of 30 minutes in all groups (P<0.005). rCBV was decreased at 30 minutes in cerebral fat embolism and recovered a little, but significantly at 2 hours. Perfusion-weighted images was useful method in offering hemodynamic information in cerebral fat embolism.

• Journal of the Korea Society of Computer and Information
• /
• v.24 no.12
• /
• pp.35-41
• /
• 2019

This paper propose design of remotely controllable hologram based interactive signage. General idea is organization of work of hologram signage through using Raspberry Pi hardware platform and Intel realsense r200 for interaction opportunity. Remote content management is based on Screenly software solution. Open CV based solutions are used for content controlling on the spectators side. Represented work describe of using of the 3D content rendering algorithm based on 3D gaming technology Unity 5. An experimental model was carried out with the purpose of IoS designing, to 3D data visualization and to introduce a new method for visualizing and displaying 3D data on a hologram pyramid signage. Description of working model of hologram signage is given in this paper.

• Journal of the Korea Computer Graphics Society
• /
• v.14 no.2
• /
• pp.19-25
• /
• 2008

We synthesize a texture with different structures at different scales. Our technique is based on deterministic parallel synthesis allowing real-time processing on a GPU. A new coordinate transformation operator is used to construct a synthesized coordinate map based on different exemplars at different scales. The runtime overhead is minimal because this operator can be precalculated as a small lookup table. Our technique is effective for upsampling texture-rich images, because the result preserves texture detail well. In addition, a user can design a texture by coloring a low-resolution control image. This design tool can also be used for the interactive synthesis of terrain in the style of a particular exemplar, using the familiar 'raise and lower' airbrush to specify elevation.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.49 no.11
• /
• pp.74-85
• /
• 2012

In this paper, we propose a optical property correction technique for a low-cost heterogeneous stereoscopic camera. Three main optical properties of a stereoscopic camera are zoom, focus, and DOF(depth of field). The difference or mis-match of these properties between two stereoscopic videos are the main causes of the visual fatigue to human eyes. The proposed correction technique reduces the difference of the optical properties between the stereoscopic videos and produces high-quality stereoscopic videos. To correct the zoom difference, a LUT(look-up table) is established to match the zoom ratio between the stereoscopic videos. To correct the DOF difference, the magnitude of image edge is measured and the lens iris is changed to control the DOF of the camera. A vertical-type stereoscopic rig is developed for the experiments of the optical property correction. Based on the experimental results, we find that a low-cost heterogeneous stereoscopic camera can be implemented, which can yield low visual fatigue to human eyes.

• Asian Journal for Public Opinion Research
• /
• v.5 no.1
• /
• pp.41-62
• /
• 2017

The political reformation in Indonesia is a determinant factor of the change in political communications and the roles of media. Currently, the political elites need media support, since it contextually has a significant role. Whoever has a good relationship with the media, will be loved by the public. On the other hand, the media also have a vested interest in the elite in running businesses and building the power of industry. Policies and capital pose a challenge to maintaining the continuity of the media. Independence and control of media are at stake, when the interests of the media and the elite collaborate with each other and then build a benefit on both sides. Meanwhile, the role of social media also cannot be neglected. The Indonesian political communication system is characterized by the presence of social media in a pseudo-relationship between the elite and the public. This paper tries to explain the growing trends of research in the academic environment and the research trends in political practice in Indonesia after the occurrence of post-reformation era in legislative and executive elections. The method used is the meta-analysis of research outcomes of university (dissertations) and secondary data sources. Data processing is done by meta-analysis of secondary data. The results of meta-analysis research indicate that, the objective conditions, in Indonesia, especially the political conditions, stimulate new spaces in communication research. The study of political communication becomes dominant in the academic environment. In addition, communication research is also characterized by a shift from the linear perspective (positivistic paradigm) to the interactive perspective (naturalistic paradigm). On the other hand, the development of politic and governance situations in Indonesia has prompted the establishment of polling agencies that help citizens understand the maps of political power and candidates in general elections and regional head elections.

• The Journal of the Korea Contents Association
• /
• v.5 no.5
• /
• pp.296-304
• /
• 2005

Quantitative analysis compare to dynamic characteristic change of the regional cerebral blood volume(rCBV) after development of cerebral fat embolism in cats using perfusion magnetic resonance(MR) Imaging. Twenty cats were used. Linoleic acid (n=11) were injected into the internal carotid artery using microcatheter through the transfemoral approach. Polyvinyl alcohol (Ivalon) (n=9) was injected as a control group. Perfusion MR images were obtained at 30 minutes and 2 hours after embolization, based on T2 and diffusion-weighted images. The data was time-to-signal intensity curve and ${\Delta}R_2^*$ curve were obtained continuously with the aid of home-maid image process algorithm and IDL(interactive data Banguage, USA) softwares. The ratios of rCBV increased significantly at 2 hours compared with those of 30 minutes (P<0.005). In conclusion, cerebral blood flow decreased in cerebral fat embolism immediately after embolization and recovered remarkably in time course. It is thought that clinically informations to dynamic characteristic change of the cerebral hemodynamics to the early finding in cerebral infarction by diffusion weighted imaging(DWI) and perfusion weighted imaging(PWI).