• Title/Summary/Keyword: interaction accuracy

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Prediction of Implicit Protein - Protein Interaction Using Optimal Associative Feature Rule (최적 연관 속성 규칙을 이용한 비명시적 단백질 상호작용의 예측)

  • Eom, Jae-Hong;Zhang, Byoung-Tak
    • Journal of KIISE:Software and Applications
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    • v.33 no.4
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    • pp.365-377
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    • 2006
  • Proteins are known to perform a biological function by interacting with other proteins or compounds. Since protein interaction is intrinsic to most cellular processes, prediction of protein interaction is an important issue in post-genomic biology where abundant interaction data have been produced by many research groups. In this paper, we present an associative feature mining method to predict implicit protein-protein interactions of Saccharomyces cerevisiae from public protein interaction data. We discretized continuous-valued features by maximal interdependence-based discretization approach. We also employed feature dimension reduction filter (FDRF) method which is based on the information theory to select optimal informative features, to boost prediction accuracy and overall mining speed, and to overcome the dimensionality problem of conventional data mining approaches. We used association rule discovery algorithm for associative feature and rule mining to predict protein interaction. Using the discovered associative feature we predicted implicit protein interactions which have not been observed in training data. According to the experimental results, the proposed method accomplished about 96.5% prediction accuracy with reduced computation time which is about 29.4% faster than conventional method with no feature filter in association rule mining.

PreSPI: Protein-Protein Interaction Prediction Service System (PreSPI: 단백질 상호작용 예측 서비스 시스템)

  • Han Dong-Soo;Kim Hong-Soog;Jang Woo-Hyuk;Lee Sung-Doke
    • Journal of KIISE:Computing Practices and Letters
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    • v.11 no.6
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    • pp.503-513
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    • 2005
  • With the recognition of the importance of computational approach for protein-protein interaction prediction, many techniques have been developed to computationally predict protein-protein interactions. However, few techniques are actually implemented and announced in service form for general users to readily access and use the techniques. In this paper, we design and implement a protein interaction prediction service system based on the domain combination based protein-protein interaction prediction technique, which is known to show superior accuracy to other conventional computational protein-protein interaction prediction methods. In the prediction accuracy test of the method, high sensitivity($77\%$) and specificity($95\%$) are achieved for test protein pairs containing common domains with teaming sets of proteins in a Yeast. The stability of the method is also manifested through the testing over DIP CORE, HMS-PCI, and TAP data. Performance, openness and flexibility are the major design goals and they are achieved by adopting parallel execution techniques, web Services standards, and layered architecture respectively. In this paper, several representative user interfaces of the system are also introduced with comprehensive usage guides.

Questionnaire Results of Subjective Evaluation of Seal Robot at the National Museum of Science and Technology in Stockholm, Sweden

  • Shibata, Takanori;Wada, Kazuyoshi;Tanie, Kazuo
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2003.09a
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    • pp.16-19
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    • 2003
  • This paper describes research on mental commit robot that seeks a different direction from industrial robot, and that is not so rigidly dependent on objective measures such as accuracy and speed. The main goal of this research is to explore a new area in robotics, with an emphasis on human-robot interaction. In the previous research, we categories robots into four categories in terms of appearance. Then, we introduced a cat robot and a seal robot, and evaluated them by interviewing many people. The results showed that physical interaction improved subjective evaluation. Moreover, a priori knowledge of a subject has much influence into subjective interpretation and evaluation of mental commit robot. In this paper, 133 subjects evaluated the seal robot, Paro by questionnaires in an exhibition at the National Museum of Science and Technology in Stockholm, Sweden. This paper reports the results of statistical analysis of evaluation data.

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Human-Computer Natur al User Inter face Based on Hand Motion Detection and Tracking

  • Xu, Wenkai;Lee, Eung-Joo
    • Journal of Korea Multimedia Society
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    • v.15 no.4
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    • pp.501-507
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    • 2012
  • Human body motion is a non-verbal part for interaction or movement that can be used to involves real world and virtual world. In this paper, we explain a study on natural user interface (NUI) in human hand motion recognition using RGB color information and depth information by Kinect camera from Microsoft Corporation. To achieve the goal, hand tracking and gesture recognition have no major dependencies of the work environment, lighting or users' skin color, libraries of particular use for natural interaction and Kinect device, which serves to provide RGB images of the environment and the depth map of the scene were used. An improved Camshift tracking algorithm is used to tracking hand motion, the experimental results show out it has better performance than Camshift algorithm, and it has higher stability and accuracy as well.

Three Dimensional Dynamic Interaction of Foundations on Layered Half-Space (3차원 다층 반무한상 구조물의 동적 간섭에 관한 해석적 연구)

  • 조우연;이강원;임윤묵;김문겸
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2001.09a
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    • pp.75-82
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    • 2001
  • A dynamic interaction analysis of an adjacent surface fecundation on a layered half-space is performed in the frequency domain. A semi-analytical approach is employed to reduce the integration range of the wavenumber in the surface fundamental solution for a layered half-space in boundary element (BE) formulations. The present study then adopts a combined boundary and finite element method to analyze the dynamic behavior of a system of flexible surface foundations on an elastic homogeneous and layered half-space. Numerical examples are presented to demonstrate the accuracy of the developed method. The examples show the feasibility of an extended application fur the complicated dynamic interaction of foundations on layered media.

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Nonlinear Dynamic Analysis of Vehicle-Bridge Interaction considering the Hertzian Contact Spring and Rail Irregularities (헤르쯔 접촉스프링과 레일 요철을 고려한 차량-교량 동적상호작용 비선형 해석)

  • Kang, Young-Jong;Neuyen, Van-Ban;Kim, Jung-Hun;Kang, Yoon-Suk
    • Proceedings of the KSR Conference
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    • 2010.06a
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    • pp.1478-1485
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    • 2010
  • In this paper, the nonlinear dynamic response of Vehicle-Bridge interaction with the coupled equations of motion including nonlinear Hertzian contact is presented. The moving train model is chosen to have 10 degrees of freedom (DOF). The bridge is modeled as 2D Euler-Bernoulli beam element with 4 DOF for each element, two for rotations and another two for translations. The nonlinear Hertzian contact is used to simulate the interaction between vehicle and bridge. Base on the relationship of wheel displacement of the vehicle and the vertical displacement of the bridge in Hertzian contact, the coupled equations of motion of the whole system is derived. The convenient formulation was encoded into a computer program. The contact forces, contact area and stress of the rail surface were also computed. The accuracy and efficiency of the proposed program are verified and compared with exact analytical solution and other previous studies. Various numerical examples and parametric studies have demonstrated the versatility and applicability of the proposed program.

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HIGH ORDER EMBEDDED RUNGE-KUTTA SCHEME FOR ADAPTIVE STEP-SIZE CONTROL IN THE INTERACTION PICTURE METHOD

  • Balac, Stephane
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.17 no.4
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    • pp.238-266
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    • 2013
  • The Interaction Picture (IP) method is a valuable alternative to Split-step methods for solving certain types of partial differential equations such as the nonlinear Schr$\ddot{o}$dinger equation or the Gross-Pitaevskii equation. Although very similar to the Symmetric Split-step (SS) method in its inner computational structure, the IP method results from a change of unknown and therefore do not involve approximation such as the one resulting from the use of a splitting formula. In its standard form the IP method such as the SS method is used in conjunction with the classical 4th order Runge-Kutta (RK) scheme. However it appears to be relevant to look for RK scheme of higher order so as to improve the accuracy of the IP method. In this paper we investigate 5th order Embedded Runge-Kutta schemes suited to be used in conjunction with the IP method and designed to deliver a local error estimation for adaptive step size control.

A Comparative study On 2D Collision Detection Algorithms For Computer Games (컴퓨터게임을 위한 2D 충돌 감지 알고리즘 비교 분석에 관한 연구)

  • Lee, Young-Jae
    • Journal of Korea Game Society
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    • v.1 no.1
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    • pp.42-48
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    • 2001
  • Collision is a brief dynamic event consisting of the close approach of two or more objects or particles resulting in an abrupt change of momentum or exchange of energy because of interaction. Collisions play very important role in computer graphics, computer games and animations fields. Collisions can supply active interaction between cyberspace and real world and give much interests for making nice games so reasonable collision detection algorithms are needed. Collision detection algorithms should satisfy being fast and accuracy. In this paper, we survey the 2D collision detection algorithms between geometric models. We present several methods and system available for collision detection.

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Evaluation of Multicenter Multielectron Integrals Using One-range Addition Theorems in Terms of STOs for STOs and Coulomb-Yukawa Like Correlated Interaction Potentials with Integer and Noninteger Indices

  • Guseinov, I. I.
    • Bulletin of the Korean Chemical Society
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    • v.30 no.7
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    • pp.1539-1542
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    • 2009
  • Using one-range addition theorems for Slater type orbitals (STOs) and Coulomb-Yukawa like correlated interaction potentials (CIPs) introduced by the author, the series expansion formulae are derived for the multicenter multielectron integrals. The expansion coefficients occurring in these relations are presented through the overlap integrals of two STOs. The convergence of series expansion relations is tested by calculating concrete cases. The accuracy of the results is quite high for quantum number, screening constants and location of orbitals. The final results are especially useful in the calculation of multielectron properties for atoms and molecules when Hartree-Fock-Roothaan (HFR) and explicitly correlated methods are employed.

A drive-by inspection system via vehicle moving force identification

  • OBrien, E.J.;McGetrick, P.J.;Gonzalez, A.
    • Smart Structures and Systems
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    • v.13 no.5
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    • pp.821-848
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    • 2014
  • This paper presents a novel method to carry out monitoring of transport infrastructure such as pavements and bridges through the analysis of vehicle accelerations. An algorithm is developed for the identification of dynamic vehicle-bridge interaction forces using the vehicle response. Moving force identification theory is applied to a vehicle model in order to identify these dynamic forces between the vehicle and the road and/or bridge. A coupled half-car vehicle-bridge interaction model is used in theoretical simulations to test the effectiveness of the approach in identifying the forces. The potential of the method to identify the global bending stiffness of the bridge and to predict the pavement roughness is presented. The method is tested for a range of bridge spans using theoretical simulations and the influences of road roughness and signal noise on the accuracy of the results are investigated.