• 한국가시화정보학회:학술대회논문집
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• 2001.12a
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• pp.36-43
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• 2001

The flow field structures of two interacting parallel supersonic free jets are studied by flow visualization using planar laser-induced fluorescence of NO seeded in nitrogen gas. The experiments are carried out for several distances between two orifice centers and for various ratios of the pressure in the reservoir to that in the expansion chamber. The flow fields are visualized mainly on the plane including two jet centerlines and its characteristic shock system, especially a cell structure formed secondly by interaction of two jets, are analyzed. The positions of the normal shock depending on the pressure ratios are also compared.

• BMB Reports
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• v.43 no.12
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• pp.795-800
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• 2010

Huntingtin-interacting protein 1-related (HIP1r) is known to function in clathrin-mediated endocytosis and regulation of the actin cytoskeleton, which occurs continuously in non-dividing cells. This study reports a new function for HIP1r in mitosis. Green fluorescent protein-fused HIP1r localizes to the mitotic spindles. Depletion of HIP1r by RNA interference induces misalignment of chromosomes and prolonged mitosis, which is associated with decreased proliferation of HIP1r-deficeint cells. Chromosome misalignment leads to missegregation and ultimately production of multinucleated cells. Depletion of HIP1r causes persistent activation of the spindle checkpoint in misaligned chromosomes. These findings suggest that HIP1r plays an important role in regulating the attachment of spindle microtubules to chromosomes during mitosis, an event that is required for accurate congression and segregation of chromosomes. This finding may provide new insights that improve the understanding of various human diseases involving HIP1r as well as its fusion genes.

• Journal of Mechanical Science and Technology
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• v.20 no.11
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• pp.1950-1960
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• 2006

Based on Banach fixed point theorem, a method to calculate nonlinear superposition for three interacting Stokes' waves is proposed in this paper. A mathematical formulation for the nonlinear superposition in deep water and some numerical solutions were investigated. The authors carried out the numerical study with three progressive linear potentials of different wave numbers and succeeded in solving the nonlinear wave profiles of their three wave-interaction, that is, using only linear wave potentials, it was possible to realize the corresponding nonlinear interacting wave profiles through iteration of the method. The stability of the method for the three interacting Stokes' waves was analyzed. The calculation results, together with Fourier transform, revealed that the iteration made it possible to predict higher-order nonlinear frequencies for three Stokes' waves' interaction. The proposed method has a very fast convergence rate.

• 한국연소학회:학술대회논문집
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• 2002.11a
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• pp.49-56
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• 2002

A two-dimensional direct numerical simulation is performed to investigate the formation characteristics of a single vortex interacting with $CH_4/N_2$-Air counterflow nonpremixed flame. The numerical method was based on a predictor-corrector scheme for a low Mach number flow. The detailed transport properties and a 16-step augmented reduced mechanism are adopted in this calculation. The budgets of the vorticity transport equation arc examined to reveal the mechanisms leading to the formation, evolution and dissipation of a single vortex interacting with counterflow nonpremixed flame. It is found that the stretching term, which depends on the azimuthal component of vorticity, and radial velocity, mainly generates vortieitv in non-reacting and reacting flows. The viscous and baroclinic torque term destroy the vorticity in non-reacting flow. In addition, the baroclinic torque term due to density and pressure gradient generates vorticity, while viscous and the volumetric expansion terms due to density gradient destroy vorticity in reacting flow.

• The Journal of Korean Society of Virology
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• v.30 no.3
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• pp.211-217
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• 2000

Nef is a lentiviral protein involved in pathogenesis of AIDS, but its molecular mechanism of action remains incompletely understood. Here we report the isolation of the interacting protein with the HIV-1 Nef, using the yeast two hybrid system for expression cloning. One of the positive colonies was selected as the final candidate for the interacting protein gene. The nucleotide sequencing revealed that this interacting protein is Human Ikaros/LyF-1. This protein interacted with the C-terminal region of Nef specifically in yeast system, not with the N-terminal region. This interaction was also confirmed by in vitro binding assay.

• Transactions of the Korean Society of Mechanical Engineers
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• v.10 no.2
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• pp.232-240
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• 1986

Extinction characteristics of the two interacting premixed flames are analyzed for the effects of flame stretch and preferential diffusion using large activation energy asymptotic analysis by adopting counterflow system as a model problem. Results show that the flammable limit of the thermally interacting premixed flames is extended compared to the single flame, and the extinction mechanism is classified into weak and strong interactions. As the lewis number of the deficient species increases, the region of strong interaction diminishes which can explain the different characteristics of the extinction boundaries of the lean (rich) methane/air and butane/air flames. The influence of the flame stretch to the interaction boundaries is also studied.

• International Journal of Control, Automation, and Systems
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• v.4 no.5
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• pp.559-566
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• 2006

In the real system application, the interacting multiple model (IMM) based algorithm requires less computing resources as well as a good performance with respect to the various target maneuverings. And it further requires an easy design procedure in terms of its structures and parameters. To solve these problems, a fuzzy interacting multiple model (FIMM) algorithm, which is based on the basis sub-models defined by considering the maneuvering property and the time-varying mode transition probabilities designed by using the mode probabilities as inputs of a fuzzy decision maker, is proposed. To verify the performance of the proposed algorithm, airborne target tracking is performed. Simulation results show that the FIMM algorithm solves all problems in the real system application of the IMM based algorithm.

• 한국전산유체공학회:학술대회논문집
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• 2002.05a
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• pp.115-120
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• 2002

A two-dimensional direct numerical simulations was peformed to investigate the flame structure of $CH_4/N_2$-Air counterflow nonpremixed flame interacting with a single vortex. The detailed transport properties and a modified 16-step augmented reduced mechanism based on Miller and Bowman's detailed reaction mechanism were adopted in this calculation. To quantify the strain on flame induced by a vortex, a scalar dissipation rate (SDR) is introduced. Results show that the fuel- and air-side vortex cause an unsteady extinction. In this case, the flame interacting with a vortex is extinguished in much larger SDR than steady flame. It was also found that air- side vortex extinguishes a flame more rapidly than fuel -side vortex.

• Structural Engineering and Mechanics
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• v.39 no.5
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• pp.683-701
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• 2011

In this study, inelastic displacement ratios and ductility demands are investigated for SDOF systems with period range of 0.1-3.0 s. with elastoplastic behavior considering soil structure interaction. Earthquake motions recorded on different site conditions such as rock, stiff soil, soft soil and very soft soil are used in analyses. Soil structure interacting systems are modeled with effective period, effective damping and effective ductility values differing from fixed-base case. For inelastic time history analyses, Newmark method for step by step time integration was adapted in an in-house computer program. Results are compared with those calculated for fixed-base case. A new equation is proposed for inelastic displacement ratio of interacting system ($\tilde{C}_R$) as a function of structural period of interacting system ($\tilde{T}$), strength reduction factor (R) and period lengthening ratio ($\tilde{T}/T$). The proposed equation for $\tilde{C}_R$ which takes the soil-structure interaction into account should be useful in estimating the inelastic deformation of existing structures with known lateral strength.

• The Journal of Natural Sciences
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• v.10 no.1
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• pp.27-32
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• 1998

To find the interacting protein with the cytoplasmic domain of HIV-1 gp41, the yeast two hybrid system was used for the expression cloning. Among the $1.4 \times 10^6 colonies, 20 colonies were selected as the final candidate for the interacting protein gene. The nucleotide sequencing revealed three kinds of protein, acidic ribosomal protein P0, beta tubulin, alpha catenin. These proteins interacted with the gp41 specifically in yeast system.