• 제목/요약/키워드: intensive observation

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Effects of High-Intensive Exercise Duration on Hematologic Properties and Cytokines in Rats (고강도운동 지속시간이 rat의 혈액학적 조성과 사이토카인에 미치는 영향)

  • Hyun, Kyung-Yae
    • Journal of Life Science
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    • v.21 no.7
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    • pp.1039-1045
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    • 2011
  • The effects of duration and time-dependent, high-intensity exercise on hematological properties and inflammation-related parameters in rats were studied. 20, 60, and 120 min of high-intensive exercise were performed daily for 8 weeks. None of the complete blood count (CBC) factors were affected by the exercise, except for the leukocyte concentration which, in the 20 min group, showed an increase of 47% compared to the control, but this was decreased after 60 min by 30% compared to the control. As exercise was performed for 60 min or longer, serum concentrations of $Fe^{++}$, unsaturated iron biding capacity (UIBC), and total iron biding capacity (TIBC) were significantly elevated in comparison to the control, where 20 min of exercise did not show any change. Both levels of interleukin-6 (IL-6), a pro-inflammatory cytokine, and interleukin-10 (IL-10), an anti-inflammatory cytokine in the serum, were elevated in response to the high-intensity exercise, however the rate of IL-6 increase was higher than the rate of exercise intensity increase, thus the offset of inflammation might be suggested. The concentration of nitric oxide (NO) in the serum became high in response to the exercise. Overall, the current observation suggests that inflammation-like responses to high-intensity exercise might be due to high circulation of blood flow and high oxygen requirement, resulting in systemic damages. However, under the current high-intensity exercise conditions, more than 20 min of exercise might not be suggested for health care purposes.

A Study on the Environment for Lowbirth Weight Infants in Neonatal Intensive Care Unit in the United States (신생아집중간호단위 환경과 저체중출생아의 반응에 대한 연구)

  • Han Kyung Ja
    • Child Health Nursing Research
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    • v.4 no.2
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    • pp.159-176
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    • 1998
  • In effort to conduct comparative study on the caregiving environment of Neonatal Intensive Care Unit(NICU) in both U. S and Korea, this study was been conducted first in the U.S. Purpose : The purpose of this study is to identify the physical environment and direct caregiving practices to lowbirth weight infants in NICU in the US. It also aims to examine the NICU outcome status and behavioral reponses of lowbirth weight infants. Methods : A study design using descriptive and inferential statistics was been conducted through an observational, field method. A sample of 15 preform infants admitted to NICU were recruited for the study. The subjects were those with birth weight between 1,000 gm to 1,500 gm, born at the gestation period of 27 to 33 weeks, and without any chromosomal or other genetic anomalies, major congenital infections, or maternal illness. Thirty minutes observation(three times of ten minutes of continuous observation)of the infant's behavior and physiological status, and an four-hour observation of the physical environment and direct care giving procedures were been conducted on the 3rd and 10th day after birth, and on the day of discharge from the NICU or at 34weeks postconception. The data to be collected were in four areas : the demograghic characteristics of the infants, the physical environment and care giving procedures, the frequency of the infant's designated behavior and physiological response, and NICU outcome variables. A descriptive analysis and Kruskal-Wallis, Pearson r were been applied according to variable characteristics. Results : 1. Mother's mean age was 29.47. The sample consisted of 6 males and 9 females. Mean gestational ages were 29.17 weeks. Mean birth weight was 1236.33g. Mean Apgar scores at one minute were 6.6, and 7.8 at five minutes. 2. The location for the incubator was in the distance from the light, X-ray screens and nursing station, in proximity to side-lamp, telephone and faucet on the third day after birth. The location for the incubator was in the distance from the light and radio on the tenth day and in proximity to nursing station on the day of dischage from the NICU or at 34weeks postconception. 3. Nesting was the most applying aids to the infants. And foot roll, shielding and plastic frame were frequently using by nurses for facilitating well modulated restful posture. 4. There were statistically significant changes in the patterns of physical environment included locating the infant's incubator and bedding, specific aids to self regulation on the 3rd and 10th day after birth, and on the day of discharge from the NICU or at 34weeks postconception. 5. Statistically significant changes were not appeared in the patterns of direct caregiving procedure to the infants included stress inducing or reducing manipulations on the 3rd and 10th day after birth, and on the day of discharge from the NICU or at 34weeks postconception. 6. The stress response of the infants in NICU were significantly reduced as the infants grow older. 7. There were not statistically significant correlation between the physical envronment and the stress responses of the infants in NICU. 8. There were statistically significant correlation between the direct caregiving procedure to the infants and the stress response of the infants in NICU in the second and third observation on the day three. 9. Average weight gain per day from birth to discharge was 38.73g, number of days in the hospital was 42.60, number of days before bottle feeding was 3.6. Postconception age starting bottle feed ing was 31/sup +5/ weeks. Number of days on mechanical ventilator was average 7.64, 11.42 was an average number of days of oxygen need. Conclusion : It, thus, appears that to minimize the sensorymotor stimulation for the low birthweight preterm infant in NICU, manipulation of care giving practices to the babies whatever the stress inducing or reducing procedures, have to be limited in the immediate early stage after birth. And it needed to be reexamine to identify the appropriate and specific physical environment and the patterns of direct caregiving to the low birthweight preform infant as the infants grow older in NICU.

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A Real-time Monitoring and Modeling of Turbidity Flow into a Reservoir (실시간 저수지 탁수 감시 및 예측 모의)

  • Chung, Se-Woong;Ko, Ick-Hwan
    • Proceedings of the Korea Water Resources Association Conference
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    • 2005.05b
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    • pp.1184-1188
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    • 2005
  • The impacts of turbidity flow induced by summer rainfall events on water supply, aquatic ecosystems, and socioeconomics are significant and major concerns in most of reservoirs operations. As a decision support tool, the real-time turbidity flow monitoring and modeling system RTMMS is under development using a laterally integrated two-dimensional (2D) hydrodynamic and water quality model. The objectives of this paper is to present the preliminary field observation results on the characteristics of rainfall-induced turbidity flows and their density flow regimes, and the model performance in replicating the fate and transport of turbidity plume in a reservoir. The rainfall-induced turbidity flows caused significant drop of river water temperature by 5 to $10^{\circ}C$ and resulted in density differences of 1.2 to $2.6kg/m^3$ between inflow water and ambient reservoir water, which consequently led development of density flows such as plunge flow and interflow in the reservoir. The 2D model was set up for the reservoir. and applied to simulate the temperature stratification, density flow regimes, and temporal and spatial turbidity distributions during flood season of 2004 After intensive refinements on grid resolutions , the model showed efficient and satisfactory performance in simulating the observed reservoir thermal stratification and turbidity profiles that all are essentially required to enhance the performance of RTMMS.

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A Case Study on Heavy Rainfall Using a Wind Profiler and the Stability Index

  • Hong, Jongsu;Jeon, Junhang;Ryu, Chansu
    • Journal of Integrative Natural Science
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    • v.8 no.3
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    • pp.221-232
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    • 2015
  • In this study, the vertical characteristics of wind were analyzed using the horizontal wind, vertical wind, and vertical wind shear, which are generated from a wind profiler during concentrated heavy rain, and the quantitative characteristics of concentrated heavy rain were analyzed using CAPE, SWEAT, and SRH, among the stability indexes. The analysis of the horizontal wind showed that 9 cases out of 10 had a low level jet of 25 kts at altitudes lower than 1.5 km, and that the precipitation varied according to the altitude and distribution of the low-level jet. The analysis of the vertical wind showed that it ascended up to about 3 km before precipitation. The analysis of the vertical wind shear showed that it increased up to a 1 km altitude before precipitation and had a strong value near 3 km during heavy rains. In the stability index analysis, CAPE, which represents thermal buoyancy, and SRH, which represents dynamic vorticity, were used for the interpretation of the period of heavy rain. As SWEAT contains dynamic upper level wind and thermal energy, it had a high correlation coefficient with concentrated-heavy-rain analysis. Through the case studies conducted on August 12-13, 2012, it was confirmed that the interpretation of the prediction of the period of heavy rain was possible when using the intensive observation data from a wind profiler and the stability index.

Development of Monitoring Site Selection Criteria of the Korean Soil Quality Monitoring Network to Meet its Purposes (토양측정망 운영목적에 따른 토양측정망 지점 선정 방안 연구)

  • Jeong, Seung-Woo
    • Journal of Soil and Groundwater Environment
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    • v.18 no.2
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    • pp.19-26
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    • 2013
  • This study developed the classification of National Soil Quality Monitoring Network (NSQM) and its site selection criteria to meet the recently established purposes of the NSQM. The NSQM were suggested by this study to classify into the six-purposes site groups from the current classification of land uses. The six purposes site groups were 1) intensive observation sites, 2) contaminant loading sites, 3) human activity sites, 4) background sites, 5) river soil sites, and 6) sites near the groundwater quality monitoring wells. Furthermore, this study developed the site selection criteria of NSQM utilizing the accumulated NSQM data, road traffic data, chemical emission data, census, soil information, and the literature related to soil quality variation due to contaminant loads. For selecting suitable sites for NSQM, this study used road traffic, chemical emission, the distance from the contaminant sources, and population information as specific criteria. The suggested site classification and criteria were appled for the current 100 NSQM sites for evaluation. Forty sites were met to the criteria suggested by this study, but sixty sites were not met to the criteria. However, some of the sixty sites also included the obscure sites that their addresses were not apparent to find them.

Epinephrine-induced lactic acidosis in orthognathic surgery: a report of two cases

  • Son, Hee-Won;Park, Se-Hun;Cho, Hyun-Oh;Shin, Yong-Joon;Son, Jang-Ho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.42 no.5
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    • pp.295-300
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    • 2016
  • Submucosal infiltration and the topical application of epinephrine as a vasoconstrictor produce excellent hemostasis during surgery. The hemodynamic effects of epinephrine have been documented in numerous studies. However, its metabolic effects (especially during surgery) have been seldom recognized clinically. We report two cases of significant metabolic effects (including lactic acidosis and hyperglycemia) as well as hemodynamic effects in healthy patients undergoing orthognathic surgery with general anesthesia. Epinephrine can induce glycolysis and pyruvate generation, which result in lactic acidosis, via ${\beta}2$-adrenergic receptors. Therefore, careful perioperative observation for changes in plasma lactate and glucose levels along with intensive monitoring of vital signs should be carried out when epinephrine is excessively used as a vasoconstrictor during surgery.

Comparison of tropical cyclone wind field models and their influence on estimated wind hazard

  • Gu, J.Y.;Sheng, C.;Hong, H.P.
    • Wind and Structures
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    • v.31 no.4
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    • pp.321-334
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    • 2020
  • Engineering type tropical cyclone (TC) wind field models are used to estimate TC wind hazard. Some of the models are well-calibrated using observation data, while others are not extensively compared and verified. They are all proxies to the real TC wind fields. The computational effort for their use differs. In the present study, a comparison of the predicted wind fields is presented by considering three commonly used models: the gradient wind field model, slab-resolving model, and a linear height-resolving model. These models essentially predict the horizontal wind speed at a different height. The gradient wind field model and linear height-resolving model are simple to use while the nonlinear slab-resolving model is more compute-intensive. A set of factors is estimated and recommended such that the estimated TC wind hazard by using these models becomes more consistent. The use of the models, including the developed set of factors, for estimating TC wind hazard over-water and over-land is presented by considering the historical tracks for a few sites. It is shown that the annual maximum TC wind speed can be adequately modelled by the generalized extreme value distribution.

Meanings of Library Catalog in Learning Activities of Korean College Students (대학생의 학습활동에 있어 도서관목록의 의미)

  • Lee, Eun-Ju;Lee, Jae-Whoan
    • Journal of Korean Library and Information Science Society
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    • v.43 no.3
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    • pp.49-77
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    • 2012
  • The purpose of this study is to investigate the values and meanings of university libraries and library catalog in the learning activities of Korean college students. Discussed in details are unique features in their library use behavior and catalog search behavior, and critical factors influencing their behavioral characteristics. A qualitative approach was employed for data collection and analysis. Intensive interviews were conducted with 30 students, also utilized was tight and close observation of their library search behavior. The result of this study is on identifying the underlying reasons why Korean students use their libraries and catalogs in a passive and limited manner.

Nitric Oxide Synthase Expressions in ADR-induced Cardiomyopathy in Rats

  • Liu, Baogang;Li, Hongli;Qu, Hongyan;Sun, Baogui
    • BMB Reports
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    • v.39 no.6
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    • pp.759-765
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    • 2006
  • In this study, we investigate Nitric oxide synthase (NOS) expressions in adriamycin (ADR)-induced cadiomyopathy in rats. Sixty male Wistar rats were randomly divided into two main groups: control and ADR groups. Myocardial histopathological observation was performed; Expressions of 3 isoforms of NOS genes were examined by RT-PCR analysis; Expressions of 3 isoforms of NOS protein was assessed by Western blot analysis. Myocardium exhibited intensive morphological changes after 8 weeks of ADR treatment. The expression levels of inducible NOS (iNOS) gene and protein were significantly increased in ADR-treated rats after 8 weeks of treatment and then slightly increased at weeks 9 and 10. No significantly difference of neuronal NOS (nNOS) or endothelial NOS (eNOS) gene and protein were observed in the myocardium obtained from the control rats and ADR-injected rats at any time point. iNOS gene expression is selectively induced by ADR in heart. The upregulation of iNOS gene and protein may be somehow correlated with morphological changes seen in heart of rat treated with ADR.

Effect of Microporosity on Tensile Properties of As-Cast AZ91D Magnesium Alloy

  • 이충도
    • Transactions of Materials Processing
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    • v.8 no.3
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    • pp.283-283
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    • 1999
  • In the present study, the effect of microporosity on the tensile properties of as-cast AZ91D magnesium alloy was investigated through experimental observation and numerical prediction. The test specimens were fabricated by die-casting and gravity-casting. For gravity-casting, the inoculation and use of various metallic moulds were applied to obtain a wide range of microporosity. The deficiency of the interdendritic feeding of the liquid phase acted as d dominant mechanism on the formation of the micropores in the Mg-Al-alloys, rather than the evolution of hydrogen gas. Although tensile strength and elongation has a nonlinear and very intensive dependence upon microporosity, the yield strength appeared to have a linear relationship with microporosity. However, it was possible to quantitatively estimate the linear contribution of microporosity on the individual tensile property far a range of microporosity, which was below about B %. The numerical prediction suggests that the effect of microporosity on fractured strength and elongation decreased as the strain hardening exponent increased. Furthermore. the shape and distribution of micropores may play a more dominant role than local plastic deformation on the tensile behavior of AZ9lD alloy.