• 한국간호교육학회지
• /
• 제28권1호
• /
• pp.15-26
• /
• 2022

Purpose: The purposes of this study was to describe the lived experience structures of married immigrant women with chronic diseases in reorganizing their lives in a variety of situations and contexts. Methods: This study applied grounded theory approach, and the participants were 15 married immigrant women with chronic disease. Data were collected through individual in-depth interviews and then analyzed by the method in Strauss and Corbin (1998). Results: The extracted data were organized 41 concepts, 21 subcategories, and 8 categories. The central phenomenon was determined to be "Life turned into a chronic disease." The causal conditions were "Undergoing physical and mental stress from marriage", "Lack of information on chronic diseases." The extracted contexts was "The demand for health resources." action and interaction strategies, "Finding problems and solutions." The intervention conditions influencing the strategies was "Establishing a support system." The result of such action was "To settle down in a way of life that suits your conditions." Conclusion: By providing a comprehensive and integrative understanding of how married immigrant women with chronic disease reorganize their lives, the study is expected to contribute to the development of social systems and national policies.

• 한국의사학회지
• /
• 제36권2호
• /
• pp.99-113
• /
• 2023

This paper is a study to find the philological basis of Bihoon (鼻熏) therapy. There is no separate philological study of Bihoon therapy to date, and for this reason, there is no clear definition or specific treatment manual. In this study, a related database was created and analyzed by examining literature data related to Bihoon therapy, focusing on Korean traditional medical books. There were about 1,000 data points related to Bihoon therapy in 45 kinds of medical books. They were largely classified into 1. Acute diseases such as insensitivity, 2. Diseases that occur in the upper human body such as nose, head, eyes, and throat, 3. Women's diseases related to childbirth, 4. Treatment of skin diseases and prevention of infectious diseases. In the case of insensitivity treatment, the focus was on awakening the patient's mind, and the treatment of diseases such as the nose, head, eyes, etc. was focused on resolving each symptom. Symptoms related to childbirth were mainly treated for uterine escapism or fainting after childbirth, while skin diseases were mainly treated for diseases that did not heal well, such as amniotic fluid. If a multifaceted approach to non-discipline therapy is added in the future, it is expected that clinical utilization will also be increased.

• 통합자연과학논문집
• /
• 제17권1호
• /
• pp.13-20
• /
• 2024

Female breast cancer is the fifth highest cause of mortality. Breast cancer is the most prevalent type of cancer in women globally, while it can also affect men. STAT5A plays a role in its development and progression. Given that activation of STAT5a is frequently linked to the growth and progression of tumors, STAT5a has been identified as a possible target for the therapy of several cancers. STAT5A, in particular, has proven to be overexpressed in various breast cancer cell lines and tumors, and it has been associated to the promotion of tumour cell proliferation and survival. STAT5A inhibition has been shown in vitro and in vivo to reduce the development of breast cancer cells. As a result, we have screened compounds from the FDA database that might serve as potential inhibitors of STAT5a through virtual screening, docking, DFT and MD simulation approaches. The drug Nilotinib has shown promising results inhibiting STAT5a. Further, in-vitro analysis will be carried forward to understand the anti-cancer activity.

• 대한한의학회지
• /
• 제44권4호
• /
• pp.1-13
• /
• 2023

Objectives: Weight counseling is an inevitable process for patients with obesity who intend to lose weight; however, the contents of real-world counseling practices remain uncertain in Korean medicine (KM) practice. This study aimed to explore the structure and constituents of obesity counseling in KM. Methods: Qualitative methods were used to explore the structure of weight counseling and clinicians' approaches to weight counseling, particularly the advice and main constituents of weight counseling in KM. Nine KM clinicians (4 women, 5 men) from nine clinics completed face-to-face, individual and semi-structured interviews from September 2019 to February 2020 in Seoul, Daejeon, Cheonan, Seongnam, Asan, and Hwaseoug. The interviews were digitally recorded, transcribed verbatim, and categorized based on their constituents. Results: During weight loss counseling, the six principal constituents of KM identified were: planning with patients, motivation, correcting misinformation on weight loss, dietary and exercise advice, medication guidance, and customized guides for each type. Conclusion: Clinicians with in-depth knowledge about obesity prescribed personalized guidance for exercise, diet, and medication through an integrative approach. The study results provide an in-depth understanding of weight counseling in KM. These six constituents could guide the counseling provided by clinicians in obesity care.

• Journal of Digestive Cancer Research
• /
• 제12권1호
• /
• pp.23-30
• /
• 2024

Borderline resectable pancreatic cancer, an intermediate stage between a completely resectable state and an unresectable state, requires a multidisciplinary treatment approach. This study aimed to elucidate the main characteristics and recent research trends regarding borderline resectable pancreatic cancer to gain further insights into them. Data from published papers about borderline resectable pancreatic cancer were collected from Web of Science (2014-2023) for the analysis. This study included 355 papers; data on major countries, publishing organizations, and keywords were collected and analyzed. Furthermore, R studio and VOSviewer were used for the qualitative and quantitative analyses of keywords. Publication of papers on borderline resectable pancreatic cancer was observed to be increasing annually by 12.8%, with the United States and Japan being the main publishing countries. In 2014, keywords related to surgery and chemotherapy were dominant; however, a shift toward more integrative approaches, such as neoadjuvant therapy, was observed over time. This study demonstrates rapidly evolving trends and paradigm changes in the research and management of borderline resectable pancreatic cancer. Thus, the results of this study are expected to contribute to establishing future research strategies and improving patient treatment outcomes.

• 생태와환경
• /
• 제39권1호통권115호
• /
• pp.62-72
• /
• 2006

수환경의 생물학적 건강도는 다양한 생물상을 이용하여 평가가 이루어져 왔으며 특히, 어류는 수환경의 건강성 평가를 위한 가장 좋은 생물종 중의 하나이다. 해부학적 기초에 의한 건강성 평가방법을 시도한 이번 예비실험의 목적은 대전시 갑천에 위치한 하수종맡처리장의 방류수가 수환경의 건강성에 어떤 영향을 미치는지 평가해 보는 것이다. 이러한 영향을 분석하기 위해 어류의 흉선(Thymus), 지느러미 (Fins), 지라 (Spleen), 후장 (Hindgut),신장 (Kidney), 피부 (Skin), 간 (Liver), 눈 (Eyes), 아가미(Gill), 및 헛아가미 (Pseudobranch)의 해부학적인 10개 메트릭을 이용하였다. 각각 2개의 대조군(control)과 처리군 (Treatment)으로 실험용 수조를 분리하여, 처리군에는 하수종말처리장의 방류수를 사용하였고 대조군에는 자연수를 사용하였으며, 각각의 수조에 버들치 (Rhynchocypris oxycephalus)를 5개체 씩 투여하였다. 투여한 버들치는 해부학적 측면의 관찰을 실시하였고, 이후 처리군의 죽은 버들치와 대조군의 개체를 각각 해부하고 10개 기관부위를 분석하여 HAI 건강도지수를 산정하였다. 해부하적 분석결과에 따르면, 3개의 대조군의 HAI지수는 0으로 나타나 최적상태로 판명되었고, 4 대조군은 40 ${\sim}$ 150점으로서 모두 악화상태로 나타났다. 또한, 생물통합지수 분석, 종풍부도분석, 내성도 및 트로픽길드 분석에 의거한 다양한 건강도 분석은 HAI 분석결과를 지지하였다. 본 HAI 기법은 현재 국내에서는 적용 평가된바 없어, 기존의 유수생태계의 건강도 평가에 상호보완적지수로의 활용도 가능할 것으로 사료된다.

• 벤처창업연구
• /
• 제7권2호
• /
• pp.113-127
• /
• 2012

IFRS에 따른 재무제표 작성은 연결재무제표의 주재무제표화, 원칙중심의 회계처리기준 등으로 인해 재무제표 본문의 간략화 및 다양화, 상세내역 및 비재무사항 주석기재 요구량 증대 등 공시 전반에 걸친 중요성이 높아지고 있다. 한편 K-IFRS체제하의 적정공시 방향에 대한 기존의 연구와 검토들은 IFRS 전면도입의 당위론적 배경과 제도변화 초기상황이라는 시기적 요인에 따라 기준제정기구나 감독기관 중심으로 공시요구사항 증대나 정보의 완전성(completeness) 측면에 초점을 두고 전개되어 온 것이 사실이다. 이에, 본 연구는 기존의 접근에 더하여 보고기업 및 정보이용자의 관점에서 보다 균형적인 IFRS 적용에 따른 적정공시 방향성을 도출하고자 하였다. 먼저 주요기업 재무공시 실태 검토 결과, 2010년, 2011년 재무공시에서 다수의 미준수사항 또는 권고할 사항이 지적되었다. 이러한 원인으로는 IFRS 기준의 성격에 따른 문제, 업종별 기업별 특성에 따른 문제, IFRS 도입비용 및 촉박한 공시기한 등 공시기업의 부담 측면이 지적될 수 있으며, 이는 정보이용자 입장에서의 이해가능성 및 활용도, 비교가능성 저하를 일으키는 것으로 나타났다. 이러한 실태의 개선을 위해, 제도의 완화/지원 측면에서 적용대상 기업의 추가 세분화 필요성 검토, 주석공시 내용과 범위 조정, 공시시기 조정 및 다원화, 공시환경 및 인센티브 지원 방안이 제안되었으며, 공시요구 강화 측면에서 기업, 정보이용자 참여비중 확대를 반영한 K-IFRS 제정체계 개선과 표준화된 세부양식 정의 및 적용의무화 필요성이 제시되었다.

• Asia pacific journal of information systems
• /
• 제17권4호
• /
• pp.133-163
• /
• 2007

Growth in the outsourcing market signals that firms of all sizes believe outsourcing will ultimately deliver many benefits and conveniences. But there are not many firms satisfied with the results of outsourcing. What is more, previous researches were fragmentary analyses focused on specific variables of outsourcing such as sourcing decisions, partnership rather than comprehensive analysis. Thus, they could not propose general systematic methodologies applicable to the real situation. To solve these problems, we developed an integrated theoretical framework that considered both contract with the hard side and trust with the soft side from a contingency viewpoint and tested this model using 143 data of Korean companies executing outsourcing. In addition, we examined how situational factors(outsourcing task complexity and outsourcing management competence) affects each path in the research model. The results of this study are as follows. First, it was proved the theory that trust is not a substitute for contract but its complement. Previous empirical studies on outsourcing success factors were focused on the establishment of successful partnership on the assumption that trust can replace contract in many situations. According to the results of our empirical analysis, however, contract and trust were in a mutually complementary relation with each other and their emphasis was different. Furthermore, different from previous researches, it was found effective to use trust as a supplementary tool and contract as a main means in outsourcing management strategy. Second, this study provided an integrated view that sees both contract and trust from a contingency viewpoint in theoretically reestablishing the relationship between contract and trust. Previous researches leaned to specific variables or theory-centered fragmentary analysis, but this study proposed a more practical and integrated research model and tested its effectiveness. Based on the results, with the model, decision makers are expected to scrutinize outsourcing situation more closely and to have a practical insight to the situation. Third, it was found that contract mechanism and trust building do not have a direct effect on outsourcing performance but relationship management intensity mediates the effect of contract mechanism and trust building. This is considered significantly meaningful to outsourcing partners who have believed that outsourcing would be successful if a contract is made properly or trust is built. Lastly, the path from trust building to relationship management intensity was moderated by informed buying, as the path coefficients from trust building to relationship management intensity varied by the degree of informed buying competence.

• 한국콘텐츠학회논문지
• /
• 제18권4호
• /
• pp.586-600
• /
• 2018

본 연구는 암 치료를 완료한 암생존자를 위한 통합 자기관리 어플리케이션 개발을 위한 기초자료를 수집하고자 시도되었다. 자기관리 프로그램은 증상관리와 신체활동관리로 구분되며 증상관리는 피로, 수면장애, 통증, 우울과 불안이 포함된다. 근거기반실무 가이드라인을 PubMed, CINAHL 및 EMBASE를 통해 검색하였으며 가이드라인 질 평가 후 최종 8개를 선정하여 분석하였다. 구조화된 표를 이용하여 스크리닝 대상자, 시기, 내용, 포괄적 사정대상자 및 사정내용을 추출하였고, 비약물적 중재 중 신체적 활동 및 운동 관련내용을 정리하였다. 통합한 결과, 암 치료 완료 후에도 모든 암 생존자를 대상으로 신뢰도와 타당도가 입증된 도구를 이용하여 정기적인 증상 스크리닝을 하여야 하고 중정도 이상의 증상 호소 시 전문가에 의한 포괄적인 사정을 요한다. 피로의 경우 신체적 활동이 일차적 중재법으로 권고되었으나 이 외 증상의 경우 보조요법 수준으로 효과가 있는 것으로 권고되었다. 따라서 암 생존자에게 꾸준한 신체적 활동을 격려하여야 하고 치료와 관련된 합병증이 없는 한 중강도의 신체활동을 꾸준히 유지할 수 있도록 중재하여야겠다. 이를 위해 신체적 활동에 대한 다양한 동기화 전략을 개발하고 적용해야 할 것으로 사료된다.

• 대한한의학회지
• /
• 제30권5호
• /
• pp.88-101
• /
• 2009

Objectives: Since Korean traditional medicine has an integrative perspective by its nature, the patients' psychological and physical problems in a Korean traditional clinic may be resolved through a more integrative approach. The purpose of this study was to describe the latent characteristics of psychological health of child outpatients and their parents visiting Korean traditional clinic with physical complaints and was to propose an alternative curriculum to meet their needs based on their psychological and physical aspects. Methods: Subjects studied consisted of 100 outpatients (59 boys, 41 girls, mean age 55 months, age range 18 to 83 months) and their parents. Behavior characteristics for children were measured by Korean version of Child Behavior Checklist for Ages 1.5-5 (CBCL1.5-5) while parenting stress, depression, and anxiety for parent were measured by Korean-Parenting Stress Index-Short Form (K-PSI-SF), Center for Epidemiologic Studies Depression Scale (CES-D) and State-Trait Anxiety Inventory (STAI), respectively. The data of subjects were compared to those of standardized groups and then were compared according to child's gender within sample. Results: Child participants were reported to have significantly higher scores of all CBCL 1.5-5 subscales than the standardized group. When compared, no differences of K-PSI-SF, CES-D, and STAI was found between parents of participants and the standardized groups. However, parents of child participants with at-risk psychological problems showed significantly higher scores of all parenting stress subscales than those of all child participants. In addition, the mothers of boy participants demonstrated significantly higher anxiety, depression and parenting stress than those of girl participants irrespective of psychological severity. Conclusions: We discussed the implication of these results in clinical situation and make recommendations for curriculum of psychiatry and pediatrics with the aim of improving proper diagnosis, consulting and treatment.