• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.4
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• pp.1938-1945
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• 2014

This study intends to investigate physical trauma in the adolescent during exercise of teenage elite judo players in Seoul. The subjects were male 67, female 14, totally 81 in middle and high school student and the data collected june the first to 28th, 2013. A data were analyzed frequency analysis, chi-square test and t-test using SPSS 16.0 program. The questionaire was contained 6 categories, experience, region, types, time, causes, intervention and preventionof sports injury. The highest results of each categories of this study is that experience of injury is 77(95.1%), region is knee 35(70.0%), type is contusion 42(54.5%), time is summer 54(70.1%), cause is body crash 40(51.9%), and intervention is going hospital 46(59.7%). To prevent physical trauma, we should recognize physical trauma durind exercise as a health problem. And to prevent physical trauma, relatives should make prevention prorgram for adolescent sports players. It will improve their quality of life.

• Journal of The Korean Association For Science Education
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• v.34 no.2
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• pp.93-105
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• 2014

Group creativity has recently been heightened as a core competence in the 21st century. Therefore, there is a need for introduction of concepts on design thinking emphasizing the collaboration and empathy to science education as an effective method for fostering group creativity. Understanding design thinking for effective introduction should be preceded, so we explore the characterizations of design thinking through the generic model overlay method, focus group interview, and critical incident technique analysis. The results reveal 4 cluster units of competency and 15 core competencies. The collaboration cluster consists of 5 competencies and they are as follows: organization of the team, communication, self-control, persuasiveness, and initiative competency. The integrative thinking cluster consists of 3 competencies and they are as follows: analytical, strategic, and intuitive thinking competency. The human-centeredness cluster consists of 3 competencies and they are as follows: user-orientation, relationship building, and interpersonal understanding competency. The multidisciplinary cluster consists of 4 competencies and they are as follows: achievement orientation, information seeking, curiosity, and flexibility competency. Findings are expected to provide the basic data for developing programs and establishing strategies in order to foster group creativity as well as introducing design thinking to science education effectively.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3825-3830
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• 2013

More studies are needed to clarify treatments and prognosis of early esophageal squamous cell carcinoma (ESCC). This retrospective study was designed to review the outcome of surgical treatment for early ESCC, evaluate the results of a left thoracotomy for selected patients with early ESCC, and identify factors affecting lymph node metastases and survival. The clinicopathological data of 228 patients with early ESCC who underwent transthoracic esophagectomy with lymphadenectomy without preoperative adjuvant treatment were reviewed. The ${\chi}^2$ test or Fisher's exact test were used to detect factors related to lymph node metastasis. Univariate and multivariate analyses were performed to identify prognostic factors. There were 152 males and 76 females with a median age of 55 years. Two hundred and eight patients underwent a left thoracotomy, and the remaining 20 patients with lymph nodes in the upper mediastinum more than 5 mm in short-axis diameter by computed tomography scan underwent a right thoracotomy. No lymph node metastasis was found in the 18 patients with carcinoma in situ, while lymph node metastases were detected in 1.6% (1/62) of patients with mucosal tumours and 18.2% (27/148) of patients with submucosal tumours. Only 7 patients showed upper mediastinal lymph node metastases in the follow-up. The 5- and 10-year overall survival rates were 81.4% and 70.1%, respectively. Only histologic grade (P<0.001) and pT category (P=0.001) significantly correlated with the presence of lymph node metastases. In multivariate analysis, only histologic grade (P=0.026) and pT category (P=0.008) were independent prognostic factors. A left thoracotomy is acceptable for selected patients with early ESCC. Histologic grade and pT category affected the presence of lymph node metastases and were independent prognostic factors for early ESCC.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.4
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• pp.361-370
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• 2017

Previous reports have suggested that physical and psychological stresses may trigger fibromyalgia (FM). Stress is an important risk factor in the development of depression and memory impairments. Antidepressants have been used to prevent stress-induced abnormal pain sensation. Among various antidepressants, tianeptine has been reported to be able to prevent neurodegeneration due to chronic stress and reverse decreases in hippocampal volume. To assess the possible effect of tianeptine on FM symptoms, we constructed a FM animal model induced by restraint stress with intermittent cold stress. All mice underwent nociceptive assays using electronic von Frey anesthesiometer and Hargreaves equipment. To assess the relationship between tianeptine and expression levels of brain-derived neurotrophic factor (BDNF), cAMP response element-binding protein (CREB), and phosphorylated cAMP response element-binding protein (p-CREB), western blotting and immunohistochemistry analyses were performed. In behavioral analysis, nociception tests showed that pain threshold was significantly decreased in the FM group compared to that in the control group. Western blot and immunohistochemical analyses of medial prefrontal cortex (mPFC) and hippocampus showed downregulation of BDNF and p-CREB proteins in the FM group compared to the control group. However, tianeptine recovered these changes in behavioral tests and protein level. Therefore, this FM animal model might be useful for investigating mechanisms linking BDNF-CREB pathway and pain. Our results suggest that tianeptine might potentially have therapeutic efficacy for FM.

• Journal of the Korea Convergence Society
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• v.8 no.12
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• pp.417-423
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• 2017

The purpose of this study was to find out how to apply CAM to college students by studying the perceptions and application factors of CAM, the actual condition of application, satisfaction according to sex, and usefulness. The subjects of this study are narrative research on H university students in Chungnam. The results of this study showed that 150(50.3%) respondents recognized CAM as an auxiliary means of modern medicine, 61(20.3%) mental and psychological stability (33.7%), and the satisfaction rate of CAM according to gender was higher in women than in men. The usefulness of CAM was 2.60, and the improvement and characteristics were 2.32 and 2.80, respectively. As a result of this study, it is necessary for university students who are the foundation of society to correctly recognize and promote CAM to prevent disease and maintain health. In addition, the analysis of the recognition and application factors of CAM, and the satisfaction according to gender, could provide information for program development of CAM in the future.

• Journal of the Korean earth science society
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• v.25 no.7
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• pp.576-585
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• 2004

This study was conducted to analyze the relationships between terms, learning concepts and inquiries in ocean unit, the National Common Basic Curriculum. The several science textbooks were selected to use for study, written in accordance with the 7 current national curriculum for the fourth grade of elementary school, the seventh of middle school and the tenth of high school. The higher the school level becomes, the frequencies of using terms related with ocean region get. The explanation of terms, however, has a tendency to be less frequent in the high school level. In the perspective of learning concept, there are more concrete concepts than formal concepts regardless of school level. Pure scientific context appears most often in inquiry contest through the whole course of every school level. In respect to inquiry process, the frequency of integrative inquiry process is on the increase as the school level gets higher. From the viewpoint of inquiry activity, there have been a lot of discussions, experiments and investigations in every school level, while high school does not the present any field study and project. Through these result, it is considered that the explanation of main terms is inevitable in the textbooks as basic educational material without regard to school level. In learning concept and inquiry context, a well-rounded learning is needed in relation to students' cognitive development and science-technology-society. Especially for the inquiry activity of earth science education, the educational effect is remarkable through field study; its appropriate application is required, accordingly.

• Korean Journal of Social Welfare
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• v.55
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• pp.27-54
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• 2003

This study examines the problems of children exposed to family violence. As a result, the children exposed to family violence exhibit various emotional, behavioral and social problems and distorted perceptions and inappropriate reactions toward family violence. Based on these results and existing programs for children exposed family violence, an integrative group program has been devised. The program was applied to two groups of the children and an experimental study was conducted to examine its effectiveness on emotional problems, aggressiveness, social skills and perceptions/reactions toward family violence. As a result, the experimental groups have shown an overall significant improvement in scores on emotional problems, aggressiveness, social skills and perceptions/reactions toward family violence. The study offers the following recommendations for clinical social work practice. First, great efforts to alleviating the problems of children exposed to family violence should be made continually. Second, special attention should be paid to reflect the characteristics of our own culture in clinical social work intervention and to do so, various practical intervention skills suitable to our culture should be developed. Finally, many different intervention models for children exposed family violence should be developed and researches comparing those models should be carried out.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.11
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• pp.897-903
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• 2015

In this paper, the contrast therapy of skin was numerically investigated by solving the conjugate heat transfer problem. A finite volume method based on the SIMPLE algorithm was adopted to solve the axisymmetric incompressible Navier-Stokes equations, coupled with an energy equation. These equations are strongly coupled with the Pennes bio-heat equation in order to consider the effect of blood perfusion rate. We investigated the thermal response of skin at some selected depths for various input temperature profiles of a stimulator for contrast therapy. From the numerical simulations, the regions with cold/hot threshold temperatures were found for five input temperature profiles. It was shown that the temperature varies mildly for different input profiles as the depth increases, owing to the Pennes effect. The input temperatures for effective hot/cold stimulation of dermis layer were found to be $47^{\circ}C$ and $7^{\circ}C$, respectively. The present numerical results will be used for finding an optimal temperature profile of a stimulator for contrast therapy.

• Journal of Society of Preventive Korean Medicine
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• v.18 no.2
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• pp.89-100
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• 2014

Objective : The co-administration effects of Gongjindan (GJD) on the pharmacokinetics (PK) of sorafenib were observed as a process of the comprehensive and integrative medicine. Methods : After sorafenib treatment, GJD was administered within 5 min. The plasma were collected at 30min before administration, 30min, 1, 2, 3, 4, 6, 8 and 24hrs after end of GJD treatment, and plasma concentrations of sorafenib were analyzed using LC-MS/MS methods. PK parameters of sorafenib ($T_{max}$, $C_{max}$, AUC, $t_{1/2}$ and $MRT_{inf}$) were analysis as compared with sorafenib single administered rats. Results : The absorption of sorafenib were significantly increased at 30min, 1, 6 and 6hrs after co-administration with GJD as compared with sorafenib single treated rats. Accordingly, the $AUC_{0-t}$ (47.20%) of sorafenib was significantly increased but $t_{1/2}$ (-30.63%) and $MRT_{inf}$ (-34.11%) in co-administered rats were non-significantly decreased. These findings are considered as direct evidences that GJD increased the oral bioavailability of sorafenib through increase of the absorption, when they co-administered within 5min. Conclusion : Based on the results, co-administration of GJD increased the oral bioavailability of sorafenib through increase of the gastrointestinal absorption. It is considered that the more detail pharmacokinetic studies should be tested to conclude the effects of GJD on the pharmacokinetics of sorafenib, when they were co-administered, like the effects after co-administration with reasonable intervals considering the $T_{max}$ of sorafenib (about 3.5hr-intervals) and after repeated co-administrations.Hence, concomitant uses of GJD with sorafenib may require close monitoring for potential drug interactions.

• Korean Journal of Ecology and Environment
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• v.39 no.1 s.115
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• pp.62-72
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• 2006

Biological health in aquatic environments has been assessed by several approaches using various bio-taxa. Especially, fish has been identified as one of the best ecological indicators for an integrative health assessments in aquatic environments. In this preliminary study, the necropsy-based approach using the Health Assessment Index (Adams et al., 1993; HAI, Blazer, 2000), was employed for the assessments of aquatic environments influenced by effluent water from wastewater disposal plants (WDP) near a urban stream (i.e., Cap-Stream). For the impact analysis from the effluents, we developed 10 metric necropsy-based model including $M_l\;skin,\;M_2\;fin,\;M_3\;thymus,\;M_4\;spleen,\;M_5\;hindgut,\;M_6\;kidney,\;M_7\;liver.\;M_8\;eyes,\;M_9\;gill,\;and\;M_{10}$ pseudobranch. We set up duplicate controls (natural upstream water plus 5 fishes in each control tank) and duplicate treatments (effluent water from the WDP plus 5 fishes in each treatment tank) in the laboratory. Preliminary results showed that HAI values in the controls were zero, indicating an excellent condition by the criteria of HAI, while the HAI values in the treatments ranged between 40 and 150, indicating a poor condition. Also, various health conditions, based on the index of biological integrity (IBI), species richness, tolerance guilds, and trophic guilds supported the HAI approach. The HAI approach, not applied in Korea, not may be used as an surrogate fer ecological health assessment in lotic ecosystems.