• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 추계학술대회 논문집
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• pp.763-768
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• 2004

CWR(Continuous Welded Rail) has many advantage over the conventional jointed rail track. The use of CWR track not only reduces the track maintenance cost, but increase the life cycle of track components. As the use of CWR increases in track structures, derailing disasters associating with track buckling also increase in great numbers due to high compressive thermal stress. Despite the importance, the number of studies relevant to the instability is quite limited. In this paper, It considers the contribution of rail-pad-fastener resistance, uplift of tie and nonlinear analysis. Influence of various track components on CWR track temperature and mode shape were characterized.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2005년도 추계 학술발표회 제17권2호
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• pp.781-784
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• 2005

Concrete structures often present volumetrical changes particularly due to thermal and moisture related shrinkages. Volumetric instability is detrimental to the performance and durability of concrete structures because structural elements are usually restrained. These restrained shrinkages develope tensile stresses which often results in cracking in combination with the low fracture resistance of concrete. Early-age defects in high-performance concrete due to thermal and autogenous deformation shorten the life cycle of concrete structures. Thus, it is necessary to examine the behavior .of early-age concrete at the stages of design and construction. The purpose of this study was to propose a shrinkage models of VES-LMC (very-early strength latex-modified concrete) at early-age considering thermal deformation and autogenous shrinkage.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 추계학술대회 논문집
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• pp.812-815
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• 2002

The shape of K-R curve for an ideally brittle material is flat because the surface energy is an unvaried material property. However, the K-R curve can take on a variety of shapes when nonlinear material behavior accompanies fracture. By the way, a general metallic material is nonlinear, structural steel is such. Therefore, the J-R curve form J-integral value instead of K parameters can be used to evaluate elastic-plastic materials with flaws in terms of ductile fracture that can be significant to design. In this paper, R-curve behaviors form K and J parameter is considered for the precise assessment of fracture analysis, in case of JS-SS400 steels.

• Steel and Composite Structures
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• 제29권4호
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• pp.509-526
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• 2018

The direct strength method adopted by the AISI Standard and AS/NZS 4600 is an advanced design method meant to substitute the effective width method for the design of cold-formed steel structural members accounting for local instability of thin plate elements. It was proven that the design strength formula for the direct strength method could predict the ultimate strength of medium strength steel welded section compressive and flexural members with local buckling reasonably. This paper focuses on the modification of the direct strength formula for the application to high strength and high performance steel welded section columns which have the nominal yield stress higher than 460 MPa and undergo local buckling, overall buckling or their interaction. The resistance of high strength steel welded H and Box section columns calculated by the proposed direct strength formulae were validated by comparison with various compression test results, FE results, and predictions by existing specifications.

• Steel and Composite Structures
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• 제12권4호
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• pp.291-302
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• 2012

Frequently, steel silos are supported by discrete supports or columns to permit easy access beneath the barrel. In such cases, large loads are transferred to the limited number of supports, causing locally high axial compressive stress concentrations in the shell wall above the supports. If not dealt with properly, these increased stresses will lead to premature failure of the silo due to local instability in the regions above the supports. Local stiffening near the supports is a way to improve the buckling resistance, as material is added in the region of elevated stresses, levelling these out to values found in uniformly supported silos. The aim of a study on the properties of local stiffening will then be to increase the failure load, governed by an interaction of plastic collapse and elastic instability, to that of a discrete supported silo. However, during the course of such a study it was found that, although the failure remains local, the cylinder height is also a parameter that influences the failure mechanism, a fact that is not properly taken into account in current design practice and codes. This paper describes the mechanism behind the effect of the cylinder height on the failure load, which is related to pre-buckling deformations of the shell structure. All results and conclusions are based on geometrically and materially non-linear finite element analyses.

• Nuclear Engineering and Technology
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• 제42권4호
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• pp.450-459
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• 2010

The present paper investigates the collapse pressure of cylinders with intermediate thickness subjected to external pressure based on detailed elastic-plastic finite element (FE) analyses. The effect of the initial ovality of the tube on the collapse pressure was explicitly considered in the FE analyses. Based on the present FE results, the analytical yield locus, considering the interaction between the plastic collapse and local instability due to initial ovality, was also proposed. The collapse pressure values based on the proposed yield locus agree well with the present FE results; thus, the validity of the proposed yield locus for the thickness range of interest was verified. Moreover, the partial safety factor concept based on the structural reliability theory was also applied to the proposed collapse pressure estimation model, and, thus, the priority of importance of respective parameter constituting for the collapse of cylinders under external pressure was estimated in this study. From the application of the partial safety factor concept, the yield strength was concluded to be the most sensitive, and the initial ovality of tube was not so effective in the proposed collapse pressure estimation model. The present deterministic and probabilistic results are expected to be utilized in the design and maintenance of cylinders subjected to external pressure with initial ovality, such as the once-through type steam generator.

• 한국공간구조학회논문집
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• 제23권2호
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• pp.19-28
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• 2023

Timber structures are susceptible to moisture, contamination, and pest infestation, which can compromise their integrity and pose a significant fire hazard. Despite these drawbacks, timber's lightweight properties, eco-friendliness, and alignment with current architectural trends emphasizing sustainability make it an attractive option for construction. Moreover, timber structures offer economic benefits and provide a natural aesthetic that regulates building temperature and humidity. In recent years, timber domes have gained popularity due to their high recyclability, lightness, and improved fire resistance. Researchers are exploring hybrid timber and steel domes to enhance stability and rigidity. However, shallow dome structures still face challenges related to structural instability. This study investigates stability problems associated with timber domes, the behavior of timber and steel hybrid domes, and the impact of timber member positioning on dome stability and critical load levels. The paper analyzes unstable buckling in single-layer lattice domes using an incremental analysis method. The critical buckling load of the domes is examined based on the arrangement of timber members in the inclined and horizontal directions. The analysis shows that nodal snapping is observed in the case of a concentrated load, whereas snap-back is also observed in the case of a uniform load. Furthermore, the use of inclined timber and horizontal steel members in the lattice dome design provides adequate stability.

• 보존과학회지
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• 제20권
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• pp.43-54
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• 2007

무량사오층석탑(보물 제185호)은 백제의 옛 땅에 위치한 지리적 특성으로 백제의 기법이 이어졌고 통일신라의 시대적인 양식도 계승된 고려초기의 석탑이다. 이 석탑은 오랜세월 외부에 위치해 있어 부재에 심한 암석학적 풍화와 생물학적 풍화를 받고 있으며 상대갑석에는 중심침하가 발생한 상태이다. 이에 상대갑석의 중심침하의 원인을 규명하기 위해 탄성파 탐사, 전기비저항 탐사, GPR 탐사와 같은 비파괴 방법을 이용하여 지반안정해석을 실시하였다. 이 결과, 모든 탐사에서 지반은 양호한 상태로 나타났으며, 특히 전기비저항 탐사자료를 통해 지반강화 다짐으로 보여지는 고비저항대가 나타났다. 따라서 상대갑석에서 발생한 중심침하 현상은 지반의 불안정에 의한 것이 아니라 상대갑석 상부 부재의 구조적 불안정에서 기인된 것이라 해석된다. 이 결과는 석탑의 상시 모니터링 또는 보존대책 수립시 기초자료로 활용될 것이다.

• Journal of Microbiology and Biotechnology
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• 제27권9호
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• pp.1711-1715
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• 2017

In this study, we characterized the $bla_{NDM-5}$-bearing plasmid in a Klebsiella pneumoniae isolate that had lost the plasmid during serial passage. We determined the complete sequences of the plasmid pCC1410-2, which was extracted from a K. pneumoniae ST709 isolate collected at a Korean hospital from which two NDM-5-producing K. pneumoniae isolates were subsequently isolated. As a result, the pCC1410-2 plasmid had a backbone structure that was similar to those of two plasmids previously reported from the same hospital, but lacked some antibiotic resistance genes ($bla_{TEM-1}$, rmtB, mphR(A), mrx(A), and mph(A)). A 9-bp repeating unit encoding three amino acids (Gln-Gln-Pro) was inserted in TraD in pCC1410-2. Thus, the pCC1410-2 plasmid might be transferred from the previously identified carbapenem-resistant K. pneumoniae, but some delections and inversions might have occurred during the process. We compared the transfer frequency and stability of the plasmids. The relative frequency of conjugative transfer and stability in the host were significantly lower in pCC1410-2 than in previously reported $bla_{NDM-5}$-bearing plasmids in Korea. A low transfer frequency and instability in the host may cause underestimation of carbapenemase-producing Enterobacteriaceae in the clinical setting and in surveillance studies.

• Journal of Gastric Cancer
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• 제8권4호
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• pp.169-175
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• 2008

목적: 대장암에서 microsatellite instability high (MSI-H)를 보인 환자가 microsatellite stable (MSS) 또는 microsatellite instability low (MSI-L)를 가진 그룹보다 예후가 좋은 것으로 되어 있으나 II기, III기 대장암에서 MSI-H를 보인 환자가 MSS 또는 MSI-L를 가진 그룹보다 5-fluorouracil (5-FU)에 대한 효과가 떨어진다는 연구 보고가 있다. Thymidylate synthase (TS)는 DNA 합성에 필요한 물질임과 동시에 5-FU의 표적물질이며 암환자에서 TS 발현율이 높을수록 5-FU에 의한 항암치료 효과가 감소한다. 이와 같이 MSI가 높을수록, TS 발현이 높을수록 5-FU에 대한 감수성이 떨어지기 때문에 MSI와 TS간의 상관관계를 밝히려는 연구가 대장암 환자를 대상으로 시도되었으나 현재까지의 결과는 상관관계가 있다는 보고와 없다는 보고가 있어서 일정하지 않다. 위암 환자에서는 MSI와 TS의 관계에 대한 연구는 없다. 따라서 본 연구에서는 위암 환자에서의 MSI와 TS 발현정도의 상관관계를 분석하였다. 대상 및 방법: 2004년 1월부터 2006년 5월까지 분당차병원에서 위암으로 근치적 위절제술을 시행 받은 환자 중 99명을 대상으로 MSI 및 TS 발현 정도를 비교 분석하였다. MSI는 5개의 표지자(BAT25, BAT26, D2S123, D5S346, D17S250)에 대해서 분석하였고 TS는 면역조직화학 염색으로 그 발현 정도를 측정하였다. 결과: 전체 99예의 환자에서 MSS/MSI-L 및 MSI-H인 경우가 각각 92 (92,9%), 7 (7.1%)예였고 TS에 대한 면역조직화학 염색 정도에 따라 negative, low TS 및 high TS인 경우는 각각 46 (46.5%), 33 (33.3%), 20 (20.2%)예였다. MSS/MSI-L 92예에서 TS의 negative, low TS, high TS는 각각 46 (50%), 30 (32.6%), 16 (17.4%)예였고 MSI-H인 7예에서는 TS의 negative, low TS, high TS가 0 (0%), 3 (42.9%), 4 (57.1%)예로 MSI-H 7예 모두에서 TS를 발현하였고 검정 결과 통계적으로 유의하게 MSI-H와 high TS 간에는 상관관계가 있었다. 결론: 위암환자에서 MSI-H를 보인 경우가 MSS/MSI-L를 보인 경우보다 더 높은 TS의 발현을 보였다.