• Journal of Oriental Neuropsychiatry
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• v.22 no.4
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• pp.111-124
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• 2011

Objectives : This case series was conducted to report the efficacy of Ondam-tanggami for insomnia. Methods : Insomnia patients with more than 15 points on Insomnia Severity Index scale were assessed using SCL-90-R, STAI, STAXI, BDI. Being treated with Ondam-tanggami after 2 weeks, ISI, STAI, STAXI, BDI were re-measured to determine the progress of insomnia. It is measured that total sleep time, number of awaking times during sleep, satisfaction of sleep daily. Results : After treatment, quality of sleep has improved and ISI, STAI, STAXI, BDI score have decreased. Conclusions : According to the study, treatment with Ondam-tanggami for insomnia has shown positive results. Further use of Ondam-tanggami is much anticipated for future treatment of insomnia cases.

• Sleep Medicine and Psychophysiology
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• v.24 no.2
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• pp.97-105
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• 2017

Objectives: To evaluate sleep characteristics and factors associated with sleep disturbance in schizophrenia patients with concurrent active psychotic symptoms and insomnia. Methods: Schizophrenia patients with insomnia and active psychotic symptoms (n = 63) were recruited from community-based mental rehabilitative facilities. Sleep scales such as the Korean version of the Insomnia Severity Index (ISI-K) and the Korean Version of the Pittsburgh Sleep Quality Index (PSQI-K) were evaluated and those with ISI-K >15 were included in the study. Psychotic, anxiety and depressive symptoms were rated with the Brief Psychotic Rating Scale (BPRS), the Korean Version of the Anxiety Sensitivity Index (K-ASI), and the Korean Version of the Beck Depression Inventory-I (K-BDI), respectively. Pearson correlation analyses were performed between the sociodemographic data, ISI-K and PSQI-K. Multiple linear regression analysis was conducted to investigate the factors which affected the ISI-K and PSQI-K. Results: The mean ISI-K and PSQI-K scores were $18.1{\pm}2.6$ and $12.0{\pm}2.2$, respectively. Pearson correlation analysis showed a negative correlation between age of onset and ISI-K score and positive correlations between BRPS and PSQI-K scores and between K-ASI and both ISI-K and PSQI-K scores. Multiple regression analyses for both ISI-K and PSQI-K with K-ASI, age of onset, and BPRS as covariates revealed K-ASI as the only significant remaining factor. Conclusion: Our study suggests that anxiety symptoms are associated with insomnia symptoms in schizophrenia patients regardless of depressive or psychotic symptoms.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.5
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• pp.892-897
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• 2010

Insomnia is common disease generating about 30% incidence in Korea. It describes not only a state of a lack of sleep but also a causative factor for both psychological and physical disorders. According to Oriental Medicine theory, there are many causes of insomnia, and Wibulhwa(胃不和) is one of causes. In this study, we diagnosed as Wibulhwa(胃不和) for three patients and mainly treated with Modified Yukgunja-tang. We compared with before and after Insomnia Severity Index(ISI) treatment. As a result, ISI score falled, and it showed an improvement in insomnia. So we suggest that Modified Yukgunja-tang might be usefully applied to the treatment of insomnia caused by Wibulhwa(胃不和).

• Journal of Oriental Neuropsychiatry
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• v.23 no.3
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• pp.63-76
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• 2012

Objectives : The aim of this study was to investigate the value and efficacy of BDI, STAI, STAXI, ISI, and SCL-90-R in correlation with depression, anxiety, and insomnia patients. Methods : A total of 39 patients, who were diagnosed with depression, anxiety, and insomnia were evaluated using BDI, STAI, STAXI, ISI, and SCL-90-R. They were then statistically analyzed. Results : 1. BDI scores of depression patients were significantly different from other patients. 2. BDI scores of depression patients had strong positive correlation with STAI-S, and STAI-T scores. 3. STAI-S scores of anxiety patients had positive correlation with BDI, and ISI scores. 4. SCL-90-R depression subscale scores of depression patients had strong positive correlation with somatization, obsessive compulsive, interpersonal sensitivity, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, global severity index, and positive symptom total subscale scores. 5. SCL-90-R anxiety subscale scores of anxiety patients had strong positive correlation with somatization, obsessive compulsive, depression, phobic anxiety, and global severity index subscale scores. Phobic anxiety subscale scores had strong positive correlation with anxiety, global severity index, and positive symptom total subscale scores. Conclusions : The result findings are expected to serve as a useful resource in future stress-related depression, anxiety, and insomnia case reports and clinical research in oriental neuropsychiatry.

• The Journal of Internal Korean Medicine
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• v.41 no.3
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• pp.494-501
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• 2020

Objectives: Insomnia is a common condition that causes deterioration of cognitive function and physical function and has a negative impact on quality of life. Insomnia is experienced by more than one-third of the population of the world. Although sleeping pills are currently used as therapeutic agents, they have side effects, so safer treatment methods are needed. Therefore, we report a case of an outpatient who sleeps only one hour a day due to insomnia. Methods: The patient visited Korean Medicine Hospital 10 times for four weeks and was treated with Korean medicine therapies, including electroacupuncture on the back-Shu points and herbal medicine (Yukmijihwang-tang and Hwangnyeonhaedok-tang). Treatment progress was assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI). Results: After 29 days of treatment, the PSQI score decreased from 20 points and 14 points. The ISI score also decreased to decreased to 22 points from 26 points. The average daily sleeping time increased from 60 minutes to 197.1 minutes after treatment. No significant side effects were observed. Conclusions: Yukmijihwang-tang and Hwangnyeonhaedok-tang with electroacupuncture might be a recommended therapeutic option for insomnia patients.

• The Journal of Korean Medicine
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• v.36 no.1
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• pp.86-92
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• 2015

Objectives: The purpose of this study is to present two treatment cases of psoriasis with insomnia. Methods: We administered Guibi-tang medication to the psoriasis patients with insomnia and tested the results by Psoriasis Area and Severity Index(PASI) and Insomnia Severity Index(ISI) as well. Results: After the treatment both the patients showed improvements in PASI and ISI as well. PASI of Patient 1 changed from 15.2 to 1.2 along with the change of ISI from 27 to 2. In case of Patient 2, PASI changed from 14.6 to 1.8 while ISI changed from 21 to 6. Conclusions: The results suggest that Guibi-tang can be an effective treatment for insomnia and psoriasis as well. Further studies will be needed to demonstrate conclusively the effect of Guibi-tang on psoriasis cure.

• Journal of Korean Public Health Nursing
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• v.32 no.2
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• pp.263-274
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• 2018

Purpose: This study examined the correlation of insomnia, sleep quality, depression, and circadian rhythm in nursing students. Methods: A total of 213 subjects completed a questionnaire consisting of their general characteristics, Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Center for Epidemiologic Studies Depression (CES-D), and Composite Scale of Morningness (CSM). The collected data were analyzed by descriptive statistics, t-test, ANOVA, and Pearson's correlation coefficient using the SPSS 23.0 program. Results: The subjects' mean scores were ISI 7.18; PSQI 11.18; CES-D 16.00; and CSM 30.18. In insomnia, there were significant differences according to caffeine, perceived health status and major satisfaction. In sleep quality, there were significant differences according to perceived health status and major satisfaction. Significant differences in depression were observed according to gender, caffeine, subjective health status, major satisfaction, and circadian rhythm by drinking and exercise. A significant positive correlation was observed among ISI, PSQI, and CES-D. ISI and CES-D were negatively correlated. Conclusion: Tailored health care programs should be developed and applied to prevent and manage sleep-related and emotion-related problems in nursing students by considering the health status, major satisfaction, and gender.

• The Journal of Internal Korean Medicine
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• v.43 no.2
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• pp.212-218
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• 2022

Objective: This study reports the effects of Gyejigeojakyakgachokchilmolyeoyonggol-tang (GCMYT) in a patient with insomnia after COVID-19 vaccination. Methods: GCMYT was used to treat insomnia following vaccination, and symptoms were evaluated using the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), and a visual analog scale (VAS). Results: The patient's PSQI, ISI, and VAS scores decreased from 21 to 11, from 25 to 13, and from 7 to 3, respectively. Conclusion: GCMYT is an effective treatment for insomnia following COVID-19 vaccination.

• Korean Journal of Psychosomatic Medicine
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• v.27 no.1
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• pp.50-59
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• 2019

Objectives : Many of the patients with type 2 diabetes are associated with sleep problems, and the rate of insomnia is known to be higher in the general population. The aims of this study were to know the frequency and clnical characteristics of insomnia, and related variables to insomnia in patients diagnosed with type 2 diabetes. Methods : For 99 patients from 18 to 80 years of age (65 males and 34 females) with type 2 diabetes, interviews were performed. Total sleep time and sleep latency was evaluated. Insomnia was evaluated using the Korean Version of the Insomnia Severity Index (ISI-K). Severity of depressive symptoms were evaluted using the Korean version of the Hamilton Depression Scale (K-HDRM). According to the cutoff score of 15.5 on the ISI-K, subjects were divided into the group of type 2 diabetics with insomnia (N=34) and those without insomnia (N=65) at first, and then statistically analyzed. Results : TInsomnia could be found in 34.34% of type 2 diabetics. Type 2 diabetics with insomnia had significantly more single or divorced (respectively 11.8%, p<0.05), higher total scores of the K-HDRS ($11.76{\pm}5.52$, p<0.001), shorter total sleep time ($5.35{\pm}2.00hours$, p<0.001), and longer sleep latency ($50.29{\pm}33.80minutes$, p<0.001). The all item scores of the ISI-K in type 2 diabetics with insomnia were significantly higher than those in type 2 diabetics without insomnia, that is, total ($18.38{\pm}2.69$), A1 (Initial insomnia) ($2.97{\pm}0.76$), A2 (Middle insomnia) ($3.06{\pm}0.69$), A3 (Terminal insomnia) ($2.76{\pm}0.61$), B (Satisfaction) ($3.18{\pm}0.72$), C (Interference) ($2.09{\pm}0.97$), D (Noticeability) ($2.12{\pm}1.09$) and E (Distress) ($2.21{\pm}0.81$) (respectively p<0.001). Variables associated with insomnia in type 2 diabetics were as following. Age had significant negative correlation with A3 items of the ISI-K (${\beta}=-0.241$, p<0.05). Total scores of the K-HDRS had significant positive correlation, while total sleep time had significant negative correlation with all items of the ISI-K (respectively p<0.05). Sleep latency had significant positive correlation with total,, A1, B and E item scores of the ISI-K (respectively p<0.05). Conclusions : Insomnia was found in about 1/3 of type 2 diabetics. According to the presence of insomnia, clinical characteristics including sleep quality as well as quantity seemed to be different. Because depression seemed to be correlated with insomnia, clinicians should pay attention to early detection and intervention of depression among type 2 diabetics.

• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.103-108
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• 2013

Objectives : Korea's average life expectancy is getting longer and longer and the pace of change in society has increased every year as people experience stress more easily. Under this situation, chronic sleep disorder is increasing, but there is no specific program for the treatment of sleep disorder in Korean medicine. Therefore, we studied a Korean medical treatment program for sleep disorder to apply to outpatient clinic patients. Methods : For this study, we evaluated the Insomnia Severity Index (ISI), BDI, STAI, FSS on 29 insomnia patients who visited Kyunghee Korean medical hospital from July 2010 to May 2012. Herbal medicine, acupuncture, herbal acupuncture, moxibustion, sleep hygiene, and medical qigong were applied. We compared ISI scores before treatment and after 4 weeks of treatment. Results : ISI score was improved after Korean medical treatment for sleep disorder. Before the treatment ISI score was 18.1, which means clinical insomnia. After the Korean medical treatment, the score was 7.5, which means no clinically significant insomnia. Conclusions : The study showed a significant effect on the Korean medical treatment program for sleep disorder to apply to outpatient clinic patients. ISI score was improved and the patients were satisfied with the treatment, so it would be more helpful to apply in sleep clinics.