• Journal of Acupuncture Research
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• 제20권4호
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• pp.114-133
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• 2003

Objective : The meridian theory in oriental medicine explains that Sp9(Yinlingquan) has been considered very important for gynecological disorders, spleen and stomach disorders, and water metabolic disorders. Functional MRI is the best method of showing the evidences of the effect of the Electro-acupuncture treatment through scientific methods. On this supposition, Electro-acupuncture stimulation on Sp9(Yinlingquan) was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). Methods : Electro-acupuncture stimulation on Sp9(Yinlingquan), the experiment was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right Sp9(Yinlingquan), 2Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. The Image analysis including motion correction, talairach transformation, and smoothing was done using SPM99. Results : The electro-acupuncture stimulation on Sp9(Yinlingquan) activates Brodmann Area 13, 19, 22, 39, 40, 47 which may be the central pathways of the electro-acupuncture stimulation on Sp9(Yinlingquan). We also hypothesize that those brain areas may be directly or indirectly related with the mechanism of the effect of electro-acupuncture stimulation on Sp9(Yinlingquan).

• Molecules and Cells
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• 제37권2호
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• pp.149-160
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• 2014

Plant breeders have focused on improving plant architecture as an effective means to increase crop yield. Here, we identify the main-effect quantitative trait loci (QTLs) for plant shape-related traits in rice (Oryza sativa) and find candidate genes by applying whole genome re-sequencing of two parental cultivars using next-generation sequencing. To identify QTLs influencing plant shape, we analyzed six traits: plant height, tiller number, panicle diameter, panicle length, flag leaf length, and flag leaf width. We performed QTL analysis with 178 $F_7$ recombinant inbred lines (RILs) from a cross of japonica rice line 'SNU-SG1' and indica rice line 'Milyang23'. Using 131 molecular markers, including 28 insertion/deletion markers, we identified 11 main- and 16 minor-effect QTLs for the six traits with a threshold LOD value > 2.8. Our sequence analysis identified fifty-four candidate genes for the main-effect QTLs. By further comparison of coding sequences and meta-expression profiles between japonica and indica rice varieties, we finally chose 15 strong candidate genes for the 11 main-effect QTLs. Our study shows that the whole-genome sequence data substantially enhanced the efficiency of polymorphic marker development for QTL fine-mapping and the identification of possible candidate genes. This yields useful genetic resources for breeding high-yielding rice cultivars with improved plant architecture.

• Journal of Digital Contents Society
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• 제6권1호
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• pp.41-48
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• 2005

In this paper, we propose and evaluate symbol timing recovery algorithm for S-DMT cable modern, which supports more channels and better quality symmetric mutimedia service over HFC network. We adopt timing recovery algorithm of PN sequence insertion in time domain and evaluate the performance of it in various noise channel such as AWGN, ISI, impulse. We verified that performance of this algorithm is depends on the channel noise environment and sampling clock offset and that over 10 dB degradation of Eb/No is occurred at the timing failure probability of $10^3$ in the composite noise channel of AWGN, ISI, and impulse in comparison with impulse noise-alone channel. finally, we verified that this algorithm showed good timing failure probability in case of sampling clock optimization was performed in advance.

• Journal of Korea Multimedia Society
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• 제15권7호
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• pp.847-858
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• 2012

In this paper, we propose a mobile watermarking based on the distortion analysis of display-capture image in a smart phone. We compose a random sequence by utilizing the property of frequency band in the wavelet domain. Then we calculate the CCS (Coefficients Comparative Sum) using the block wavelet coefficients of selected subbands after the wavelet transformation and the random sequence and repeatedly embed a watermark using an insertion threshold for the watermark robustness. For correcting a distortion caused by the display-capture process, we adopt a frame at the outside of watermarked image, then we can equate a watermark synchronization by detecting the frame. And we can improve frame detection ratio by using an iteratively adaptive threshold. A proposed scheme embedded information of 206 bits into standard digital images and it shows an average about 41.42 dB in PSNR. In watermark extract experiments, a proposed scheme accurately recognizes the frame more than 97% in total captured images. Also in BER (Bit Error Ratio) of captured images, it shows about 3.73%, then it was improved more than 70%, compared with the Pramila's method.

• The Journal of Korean Institute of Communications and Information Sciences
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• 제32권10A호
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• pp.1034-1041
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• 2007

In this paper, we propose a FD USE (frequency domain minimum mean square error) equalizer algorithm for MBOK DS-UWB (M-ary bi-orthogonal keying direct sequence UWB) systems considered as a PHY proposal for high-speed wireless communication in IEEE 802.15.TG3a. The conventional FD MMSE equalization scheme has a structural limit due to insertion of the cyclic prefix (CP) in all transmit packets, but the proposed scheme is able to equalize the channel effect without CP. In order to overcome channel estimation error by multipath delay, we introduce a moving FFT and a moving average scheme. Compared with conventional FD MMSE equalizer and the traditional TD (time domain) MMSE-RAKE receiver, the proposed FD MMSE equalizer has better BER performance and we demonstrate this result by computer simulation.

• Animal Systematics, Evolution and Diversity
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• nspc3호
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• pp.139-146
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• 1992

The primary sequence of the 18S rRNA gene of a crustacean Pugettia quadridens (Decapoda: Pleocyemata: Brachyura) was determined by the PCR cloning and Taq sequencing. The 18S rRNA gene of this species in 1837 bases long, and 46 bases shorter than that of another crustacean decapod Oedignathus inermis. The similarity between two species is 90.8% when the insertion and/or deletion sites were excluded. Within the molecule, the most conservative (identical) region locates at the position of 1137-1206 and it is 70 bases long. The most long consecutive nucleotide differences occur at the position between 46-55 and the second most between 399-407. The sequence variation in the primary structure of 18S rRNA gene are not evenly distributed throughout the molecule.

• The Transactions of the Korea Information Processing Society
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• 제1권4호
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• pp.479-489
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• 1994

At the present time, it is an important problem that we are to select a transmission line code for the very-high speed optical transmission system which can confidentially transfer the original information signal sequence efficiently, as it is to be the large capacity and the economization for the optical digital transmission system to transfer the information signal sequence at the very-high speed. Therefore, this paper is to select first the proper transmission line codes for the high speed(more than Mb/s) optical transmission system of the proposed two-level unipolar transmission line codes up to date, and to decide a mBIZ (m Binary with One Zero insertion) code as an optimal transmission line code for the very-high speed optical transmission system, resulting from analyzing the performance at the requirements of the transmission line code, such as the maximum consecutive identical digits, the transmission delay time, the increasing rate of clock, the mark rate, the circuit complexity, the supervision of transmission line error, and power spectrum among the selected transmission line codes.

• Genomics & Informatics
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• 제3권2호
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• pp.61-65
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• 2005

Comparing 231 genes on chimpanzee chromosome 22 with their orthologous on human chromosome 21, we have found that 15 orthologs have indels within their coding sequences. It was rather surprising that significant number of genes have changed by indel, despite the shorter time since their divergence and led us hypothesize that indels and structural changes may represent one of the major mechanism of proteome evolution in the higher primates. Human T-complex protein 10 like (TCP 10L) is a representative having indel within its coding sequence. Gene structure of human TCP10L compared with chimpanzee TCP10L gene showed 16 base pair difference in genomic DNA. As a result of the indel, frame shift mutation occurs in coding sequence (CDS) and human TCP10L express longer polypeptide of 21 amino acid residues than that of chimpanzee. Our prediction found that the indel may affect to dramatic change of secondary protein structure between human and chimpanzee TCP10L. Especially, the structural changes in the C-terminal region of TCP10L protein may affect on the interacting potential to other proteins rather than DNA binding function of the protein. Through these changes, TCP10L might influence gene expression profiles in liver and testis and subsequently influence the physiological changes required in primate evolution.

• International Journal of Industrial Entomology and Biomaterials
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• 제37권2호
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• pp.82-89
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• 2018

This study was carried out to understand phylogenetic relationships of the 30 mulberry cultivars converved in Korea based on the ITS rDNA region, and they were compared to 40 reference sequences from GenBank. The size and the G+C content of the ITS rDNA gene regions from the 30 Korean mulberry cultivars and 40 reference sequences varied from 612-630 bp and 58.19-61.62%, respectively. Based on the results of the comparative phylogenetic analysis of the ITS rDNA regions of the 30 Korean mulberry cultivars and 40 reference sequences, they were divided into three groups (Group 1, 2, and 3) and two subgroups (Group 1A and 1B within Group 1). The sequence lengths of the Korean mulberry cultivar numbers 1-26 and 27-30 were 615 bp and 616 bp, respectively. At 205 bp location of ITS1 rDNA region, the cultivar numbers 1-26 contain the nucleotide thymine but the cultivar numbers 27-30 contain the nucleotide adenine. In addition, the insertion of the nucleotide adenine at 206 bp location was found only in the four Korean mulberry cultivars (numbers 27-30). Based on these sequence information and phylogenetic result, the 30 Korean mulberry cultivars were identified as M. alba and M. australis. This study will contribute to the construction of genetic database constructions and accurate variety identifications for unidentified mulberry varieties in Korea.

• Microbiology and Biotechnology Letters
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• 제47권1호
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• pp.25-33
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• 2019

Lactobacillus rhamnosus BFE5264, isolated from a Maasai fermented milk product ("kule naoto"), was previously shown to exhibit bile acid resistance, cholesterol assimilation, and adhesion to HT29-MTX cells in vitro. In this study, we re-annotated and analyzed the previously reported complete genome sequence of strain BFE5264. The genome consists of a circular chromosome of 3,086,152 bp and a putative plasmid, which is the largest one identified among L. rhamnosus strains. Among the 2,883 predicted protein-coding genes, those with carbohydrate-related functions were the most abundant. Genome analysis of strain BFE5264 revealed two consecutive CRISPR regions and no known virulence factors or antimicrobial resistance genes. In addition, previously known highly variable regions in the genomes of L. rhamnosus strains were also evident in strain BFE5264. Pairwise comparison with the most studied probiotic strain L. rhamnosus GG revealed strain BFE5264-specific deletions, probably due to insertion sequence-mediated recombination. The latter was associated with loss of the spaCBA pilin gene cluster and exopolysaccharide biosynthetic genes. Comparative genomic analysis of the sequences from all available L. rhamnosus strains revealed that they were clustered into two groups, being within the same species boundary based on the average nucleotide identities. Strain BFE5264 had a sister group relationship with the group that contained strain GG, but neither ANI-based hierarchical clustering nor core-gene-based phylogenetic tree construction showed a clear distinctive pattern associated with the isolation source, implying that the genotype alone cannot account for their ecological niches. These results provide insights into the probiotic mechanisms of strain BFE5264 at the genomic level.