• BMB Reports
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• v.51 no.2
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• pp.85-91
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• 2018

Pluripotent stem cell (PSC) variations can cause significant differences in the efficiency of cardiac differentiation. This process is unpredictable, as there is not an adequate indicator at the undifferentiated stage of the PSCs. We compared global gene expression profiles of two PSCs showing significant differences in cardiac differentiation potential. We identified 12 up-regulated genes related to heart development, and we found that 4 genes interacted with multiple genes. Among these genes, Gata6 is the only gene that was significantly induced at the early stage of differentiation of PSCs to cardiomyocytes. Gata6 knock-down in PSCs decreased the efficiency of cardiomyocyte production. In addition, we analyzed 6 mESC lines and 3 iPSC lines and confirmed that a positive correlation exists between Gata6 levels and efficiency of differentiation into cardiomyocytes. In conclusion, Gata6 could be utilized as a biomarker to select the best PSC lines to produce PSC-derived cardiomyocytes for therapeutic purposes.

• Korean System Dynamics Review
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• v.14 no.3
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• pp.25-49
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• 2013

As global competition for green car, that is environmentally friendly car, is getting tougher, the governments and the related industries are putting their core efforts in its diffusion. However, the green car sales are disappointing so far. To overcome the gridlock, it is necessary to develop concrete analytical framework to understand the diffusion process. Based on causal loop analysis from the previous work, we have identified main variables and relationships of them in the diffusion process and developed a stock-flow diagram and mathematical formula for the main components. The model would be applied for further quantitative simulation on the diffusion process of green car and other innovative goods as well. Also, we have suggested constructive insights for the policy makers and for the related industries. First, it is important to increase consumers' willingness to consider through marketing and word of mouth to accelerate the diffusion process. Second, in the perspective of the industry, the market share of green car should be increased at the earliest possible stage and this could be done by enhancing each components of green car attractiveness(e.g. price, driving range, social infra). Third, companies should develop a balanced investment between consumer and technology sector through a flexible financial policy. Fourth, the government continuously has the role of investing in the related R&D and social infra building. We expect the green car diffusion model and related formula from the research can provide meaningful tools to analyze the diffusion process of other new and innovative goods based on its deep researched literature review.

• Korean Medical Education Review
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• v.25 no.2
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• pp.109-113
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• 2023

An educational outcome cohort has been established at Keimyung University School of Medicine to help make educational policy decisions and improve educational programs based on data. The purpose of the educational outcome cohort is to support educational policy decisions for achieving graduation outcomes smoothly and to accomplish the intended human resources development of the university through objective analyses and regular monitoring, providing continuous feedback. The data collected for the educational outcome cohort include the student identifications of freshmen, entrance exam scores, premedical and medical school grades, titles and forms of student academic research, the results of psychological testing, scholarship recipient lists, volunteer clubs, and so forth. The data are collected using an information utilization agreement approved by the Institutional Review Board, and the collected data are encrypted and stored on a dedicated computer for enhanced personal information security. Proposals to access and utilize the educational outcome cohort data must be discussed and approved by the Educational Outcome Cohort Committee, which decides on the scope and method of utilization. The collected and managed educational outcome cohort data have been used to develop comparative programs to improve students' competency and to support admission policy decisions through an analysis of the characteristics and performance of medical school students. The establishment and utilization of the educational outcome cohort will play an important role in determining the School of Medicine's educational policies and suggesting new directions for educational policies in the future.

• Journal of Korea Foundry Society
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• v.30 no.4
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• pp.126-129
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• 2010

• Proceedings of the Korean Nuclear Society Conference
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• 2004.05a
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• pp.391-391
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• 2004

• Science of Emotion and Sensibility
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• v.11 no.4
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• pp.645-652
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• 2008

First question: what makes inclusive design truly inclusive? Most inclusive design products are far from being appealing to their intended customers. This is mainly because designers are typically concerned with enhancing the usability, and not the emotional value that creates the connection between the product and the users. Typical solutions are larger displays and larger buttons, and these solutions often make the product less tasteful, graceful, and favorable. As a result, such products become less inclusive, veering from the original intention of the designers. Emotional design is not about making fun products, but about enjoyable products. Positive emotional design increases the affection value in products that enable users to create emotional connection with products. With the emotional connection, the user can engage in learning about the product as well as enjoy using the product. This can also resolve most usability issues by increasing the attention level and decreasing boredom. When more people feel that a product is enjoyable, it becomes more inclusive. Second question: Can't inclusive design have innovative value? Most inclusive design products are far from being innovative, and thus, they cannot create market opportunities. While emotional design approach increases value for users, innovative design approach creates value for the businesses. This will eventually promote development of inclusive products. This paper discusses the benefits of emotional design approach in inclusive design. It also argues how emotional design can help make inclusive design more innovative. Accompanied exemplar design process illustrates how emotional design contributes to inclusive design and how it leads to innovative products.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.7 no.2
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• pp.63-76
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• 2012

The possibility of successful commercialization of technologically innovative products depends on the degree to which consumers select and utilize the product. Therefore, the research that endeavors to find the usage behavior and the acceptance intention of users of technologically innovative products is a very important quest. This study empirically analyzes the factors that influence commercialization of a technologically innovative product: cloud computing. Existing studies examined acceptance intentions by expanding the TAM model and excluded attitude and usage behavior. This study determined attitude, usage behavior and personal characteristics of consumers to be important influencing factors. The results of the empirical analysis are as follows: First, the self-efficacy of personal characteristics had a significant effect on ease of use and acceptance intention and perceived costs had a significant influence on the factors of perceived usefulness and perceived ease of use. Second, research on the systematic characteristics of cloud computing confirmed that security was an important factor affecting acceptance intention while innovativeness was critical to ease of use. Third, of the usage characteristics among users of technologically innovative products, perceived usefulness had an effect on the acceptance and usage behavior of cloud computing, and perceived ease of use had an important influence on perceived usefulness. Currently, when cloud computing services have not yet become widespread to the public, this study proposed meaningful results for policy direction and commercialization strategies by revealing variables that influence acceptance and usage behavior.

• Journal of Appropriate Technology
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• v.6 no.2
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• pp.126-135
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• 2020

Recently, with the development of the 4th Industrial Revolution era and the popularization of technologies the maker movement is spreading worldwide in various ways for education, entrepreneurship, and solving social problems. This paper introduces a case of establishing and operating a maker space in Tanzania, East Africa, one of the developing countries. iTEC Tech-shop was established in the first half of 2018 at the Nelson Mandela African Institution of Science and Technology (NM-AIST) in Arusha, Tanzania by Innovative Technology and Energy Center (iTEC), and has been operating for nearly two years. With the allocation of empty warehouse space from NM-AIST, physical facilities were established through the purchase and installation of equipment and hand tools. Based on the advice from Idea Factory of Seoul National University and Fab-Lab Seoul, iTEC Tech-shop operational system were established. Through a total of 7 technical workshops, iTEC Tech-shop provided training courses for about 180 local personnel. In addition, the smart Techshop test-bed project was promoted in order to improve the operation level along with securing sustainability of the Techshop. The case of the iTEC Tech-shop could be a useful case for institutions or organizations promoting the maker movement to developing countries.

• The Korean Journal of Air & Space Law and Policy
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• v.27 no.1
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• pp.157-169
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• 2012

China's Space Activities in 2011 (thereafter 2011 White Paper) was published by Information Office of State Council of the Peoples Republic of China on December 29, 2011, and it was the third space white paper after 2000's space white paper and 2006's space white paper. The 2011 White Paper summarizes splendid achievements China had received in space area since 2006, and systematically introduces the principles of China's space activities; at the same time, it also presents the world the policies, measures and key areas of China's space activities in the following five years. This 2011 White Paper is the most detailed, concrete, and integrated elaboration of China's space policy, and it will be the guideline for China to explore outer space with peaceful purpose in the next five years. Compared with 2000's and 2006's White Papers, the 2011 White Paper indicated that Chinese government adjusted space policies under the new circumstance. The 2011 white paper stressed China's position on use of outer space for peaceful purpose and highlighted the new idea of scientific and innovative development in space industry in the next five years.

• Journal of the Korean Society for Advanced Composite Structures
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• v.5 no.1
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• pp.28-36
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• 2014

This study describes the development of innovative connections between steel beams and concrete-filled tube columns that utilize a combination of low-carbon steel and super-elastic shape memory alloy components. The intent is to combine the recentering behavior provided by the shape memory alloys to reduce building damage and residual drift after a major earthquake with the excellent energy dissipation of the low-carbon steel. The analysis and design of structures requires that simple yet accurate models for the connection behavior be developed. The development of a simplified 2D spring connection model for cyclic loads from advanced 3D FE monotonic studies is described. The implementation of those models into non-linear frame analyses indicates hat the recentering systems will provide substantial benefits for smaller earthquakes and superior performance to all-welded moment frames for large earthquakes.