• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.302-313
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• 2016

This study conducts statistical analysis based on a survey of 300 CEOs from Korean companies in order to examine the effects of a CEO's internal?external activities (information, knowledge management, learning organization) on business innovation activity (exploitative, exploratory) and business performance. Analysis results show that learning organization activity had a significant positive (+) effect on exploitative and exploratory innovation activity. In addition, knowledge management activity lacked statistically significant effects on exploratory innovation activity. Furthermore, exploitative and exploratory innovation activity was affected by CEO's internal?external activities (information, knowledge management, learning organization) and had a significant positive (+) effect on company's business performance. but it was shown that the level of influence was different. Results of this study imply that maximizing business performance through developing innovation activity by CEO's internal?external activities (information, knowledge management, learning organization) in the company, extracting activity advantageous to company's business environment based on activity perceived in the precedent study and business strategy becomes advantageous to the attainment of business performance objectives.

• Journal of Technology Innovation
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• v.27 no.3
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• pp.113-142
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• 2019

Based on the Knowledge Spillover Theory of Entrepreneurship, this study analyzes the relationship between technological entrepreneurship and national competitiveness. It also analyzes how innovation-driven economy moderates this relationship. Using data on technological entrepreneurship, national competitiveness indexes and economy development stages from 83 countries over 2011 to 2014, this study finds that a ratio of technology-based start-ups in a country has a U-shaped relationship with national competitiveness. this study also finds that countries that are in the innovation-driven economy strengthen this relationship. This finding shows that a higher ratio of technology-based start-ups of a country does not have unconditional positive effects on national competitiveness, thus, related environments and conditions should be elaborately matched. In particular, this finding also implies that policies related to technology-based start-ups should have a proper fit with the level of economic development of the country so that the positive effects of technological entrepreneurship on national competitiveness can be strengthened.

• Journal of the Korea Society of Computer and Information
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• v.12 no.4
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• pp.209-219
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• 2007

Since 100PPM Quality Certification System has been established by the Industrial Advancement Administration in 1995, 100PPM duality Innovation movement has contributed much to the enhancement of qualify competitiveness of Korea's parts industry. And in 2000, raised to a higher level, Single PPM qualify Certification System has been established by the Small and Medium Business Adminstration. The quality target is below the 10ppm(parts per million) in outgoing qualify and delivered goods plus field claim. Recently 1.818 companies is received Single PPM Quality Certification from Government. Single PPM Quality Innovation movement is perfection movement which is suitable for 21C's social-economical criteria to pursuit of zero defect. The purpose of this study is to suggest the Kano Model based Global Sustainable duality Innovation(GSQI) Index to improve current problems of Single PPM Quality Innovation Movement.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.36 no.3
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• pp.109-117
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• 2013

This study designed a "Diagnostic Model for Management Innovation of Medium Enterprises" based on the theoretical background of success factor and management diagnosis model for management innovation of medium enterprises and suggested a measure for utilization of strategic subject and diagnostic model that enterprises can apply. Utilization of medium enterprises management innovation diagnostic model designed through this study would be of help for making a diagnosis of the capability maturity level of enterprises' current management system and improving it by establishing a challenging capability objective and building a circulation system capable of innovating enterprises. It is expected for enterprises to overcome growing pains and establish a management system capable of achieving outcome (productivity) by repeating measurement and innovation through management diagnosis. In addition, this study provides a method to produce a strategic subject, select priority of implementation and prepare an implementation road map by classifying and filtering management issues produced as a result of management diagnosis in a systematic way. If variables necessary for production of an objective weighted value of scoring and discover of elements for category of diagnostic model and elementary items as well as design of a self-diagnosis questionnaire, measurement of management outcome suggested in this study can be able to be verified and supplemented through case study in the future, it is expected to make the degree of completion as a diagnostic model elevated that may help for growth and development through innovation of medium enterprises.

• Asia-Pacific Journal of Business
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• v.10 no.4
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• pp.49-63
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• 2019

The export regulation of semiconductor core materials, which began with the recent revision of the export management regulations of Japan, raises the need for a new cooperation network. A hierarchical management network that was effective in the fast-follower system requires organic cooperation between the public sector and industry through a multilateral network that emphasizes horizontal co-operation among innovation actors. This study focused on the relational capital that exists among members of a business association such as an association that has been relatively marginalized from previous studies. In addition, this study aimed to analyze the effect of network activity characteristics such as industry-university linkage and informal exchange on technological innovation. Through this, I would like to draw implications for enhancing the effectiveness of the government's R & D support and innovation performance of R & D companies. Based on the results of the SMEs R & D survey, this study found that relational capital, informal exchange had a positive effect on technological innovation performance. However, if the relational capital exceeds a certain level, it is analyzed that there is a negative effect due to group think and lock-in effect. This means that informal exchange channels should be expanded for innovation and enhancement, and relational capital should be managed in consideration of the negative effects that may occur when certain levels are exceeded.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.45 no.3
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• pp.186-196
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• 2022

In recent years, ESG activities (Environment, Social and Governance) have been paid more and more attention by enterprises and their stakeholders in various countries. China is the largest developing country in the world. The ESG performance of Chinese listed enterprises helps to understand the shortcomings of their sustainable development ability and further enhance the firm value. Moreover, the interaction effect between green innovation investment and ESG activities is of great significance for enterprises to balance the resource allocation between the two factors in the future. Taking listed Chinese manufacturing companies from 2011 to 2020 as an example, this study investigates the influence of ESG activities on financial performance and non-financial performance, and tests the moderating role of green innovation. Our results show that: (1) ESG performance has a negative impact on financial performance; (2) ESG performance has a positive impact on non-financial performance; (3) Green innovation can positively adjust the negative impact of environmental activities on financial performance. However, it will enhance the negative impact of governance activities on financial performance. The interaction effect between green innovation and social activities on corporate financial performance is a substitution effect; (4) With the improvement of green innovation level, the positive impact of ESG overall performance and environmental performance on corporate reputation will also be suppressed.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.89-96
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• 2023

Background and aim: Panax ginseng, a key herbal medicine of replenishing Qi and tonifying Spleen, is widely used in the treatment of gastrointestinal diseases in East Asia. In this study, we aim to investigate the potential effects and mechanisms of polysaccharides from P. ginseng (PGP) on intestinal mucosal restitution which is one of the crucial repair modalities during the recovery of mucosal injury controlled by the Ca²⁺ signaling. Methods: Rat model of intestinal mucosal injury was induced by indomethacin. The fractional cell migration was carried out by immunohistochemistry staining with BrdU. The morphological observations on intestinal mucosal injury were also performed. Intestinal epithelial cell (IEC-6) migration in vitro was conducted by scratch method. Western-blot was adopted to determine the expressions of PLC-𝛾1, Rac1, TRPC1, RhoA and Cav-1. Immunoprecipitation was used to evaluate the levels of Rac1/PLC-𝛾1, RhoA/TRPC1 and Cav-1/TRPC1. Results: The results showed that PGP effectively reduced the assessment of intestinal mucosal injury, reversed the inhibition of epithelial cell migration induced by Indomethacin, and increased the level of Ca²⁺ in intestinal mucosa in vivo. Moreover, PGP dramatically promoted IEC-6 cell migration, the expression of Ca²⁺ regulators (PLC-𝛾1, Rac1, TRPC1, Cav-1 and RhoA) as well as protein complexes (Rac1/PLC-𝛾1, Cav-1/TRPC1 and RhoA/TRPC1) in vitro. Conclusion: PGP increases the Ca²⁺ content in intestinal mucosa partly through controlling the regulators of Ca²⁺ mobilization, subsequently promotes intestinal epithelial cell migration, and then prevents intestinal mucosal injury induced by indomethacin.

• International Journal of Contents
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• v.18 no.1
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• pp.1-16
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• 2022

With the advent of the 5G, networks and information and communication technologies have been continuously developed. In the fields of art galleries, virtual reality (VR) exhibitions that can be visited online have emerged, innovating the way of human-computer interaction and creating new artistic experiences for users. This study explores the three-dimensionality, clarity, and innovative interactions that users experience when viewing a VR exhibit, which affects the exhibit's presence. Besides, in terms of research method, the research sets spatial participation and immersion as dependent variables, with three-dimensionality (high versus low), clarity (high versus low), and innovation (high versus low) in a 2×2×2 design as the base, and explores their interaction effects. The results show that three-dimensionality and innovative interactions affect spatial participation. First of all, in groups with high innovation and low three-dimensionality, spatial participation presents a higher positive factor. Secondly, with regard to immersion, three-dimensionality, clarity and innovation present a tripartite interaction. Groups with low three-dimensionality and high clarity have a higher positive effect on immersion when the level of innovation is low. When the degree of innovation is high, the positive effect on immersion is higher in groups with high three-dimensionality and low clarity. The above results show that in the production of VR exhibitions, it is necessary to increase the three-dimensionality and clarity of exhibited image contents, while taking into account the user's perception and innovativeness. On the other hand, this study puts forward suggestions for the design, content and future development of VR exhibitions, which has important reference significance for the improvement and innovation of future VR exhibitions.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.7
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• pp.920-929
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• 2017

Objective: The bursa of Fabricius (BF) is a central humoral immune organ belonging specifically to avians. Recent studies had suggested that miRNAs were active regulators involved in the immune processes. This study was to investigate the possible differences of the BF at miRNA level between two genetically disparate duck breeds. Methods: Using Illumina next-generation sequencing, the miRNAs libraries of ducks were established. Results: The results showed that there were 66 differentially expressed miRNAs and 28 novel miRNAs in bursa. A set of abundant miRNAs (i.e., let-7, miR-146a-5p, miR-21-5p, miR-17~92) which are involved in immunity and disease were detected and the predicted target genes of the novel miRNAs were associated with duck high anti-adversity ability. By gene ontology analysis and enriching KEGG pathway, the targets of differential expressed miRNAs were mainly involved in immunity and disease, supporting that there were differences in the BF immune functions between the two duck breeds. In addition, the metabolic pathway had the maximum enriched target genes and some enriched pathways that were related to cell cycle, protein synthesis, cell proliferation and apoptosis. It indicted that the difference of metabolism may be one of the reasons leading the immune difference between the BF of two duck breeds. Conclusion: This data lists the main differences in the BF at miRNAs level between two genetically disparate duck breeds and lays a foundation to carry out molecular assisted breeding of poultry in the future.

• Korean small business review
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• v.43 no.1
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• pp.51-83
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• 2021

This study empirically examined how the technology innovation competence of the 4th Industrial Revolution Enterprises affects management performance. It also analyzed whether there would be any difference in business performance between the 4th Industrial Revolution Enterprises and the non-4th Industrial Revolution Enterprises. The samples for analysis were analyzed using in-situ data of 2,543 enterprises classified as technical innovation enterprises and the 4th Industrial Revolution Enterprises through Korea Technology Finance Corporation's in-house technical evaluation. Variables for technology innovation competence were analyzed using variables such as the size of manpower of research and development, the level of research and development organizations, the number of intellectual property rights, the ratio of intangible assets, the amount of knowledge properties, the amount of research and development investment, and the intensiveness degree of research and development. In terms of the impact of the 4th Industrial Revolution Enterprises' technology innovation competence on business performance, all factors except for the level of research and development organizations were found to affect business performance, which supported the study hypothesis. In particular, it was confirmed that the amount of knowledge properties has had a relatively greater impact on business performance. In addition, the average comparative analysis between the 4th Industrial Revolution Enterprises and the non-4th Industrial Revolution Enterprises confirmed that the 4th Industrial Revolution Enterprises conducted higher values in the business performance.