• Advances in Traditional Medicine
• /
• 제7권5호
• /
• pp.556-563
• /
• 2008

Peripheral nerve injuries are a commonly encountered clinical problem and often result in a chronic pain and severe functional deficits. The expression of c-Fos is sometimes used as a marker of increased neuronal activity. We have prepared the aqueous extract of amygdalin from Armeniacae semen for pain control. In the present study, we investigated the effects of amygdalin on the recovery rate of the locomotor function and on the expression of c-Fos in the ventrolateral periaqueductal gray (vlPAG) region following sciatic crushed nerve injury in rats. Walking track analysis for the evaluation of functional recovery and immunohistochemistry for the c-Fos expression were used in this study. In the present results, characteristic gait change with dropping of the sciatic function index (SFI) was observed and c-Fos expression in the vlPAG was suppressed following sciatic crushed nerve injury in rats. Amygdalin enhanced SFI value and restored c-Fos expression in the vlPAG to the control value. The present our study indicated that amygdalin activates neurons in the vlPAG, and it facilitates functional recovery following peripheral nerve injury.

• 대한한방내과학회지
• /
• 제43권5호
• /
• pp.817-826
• /
• 2022

Objectives: The aim of this study is to report a case in which a patient showed recovery from hemiparesis after a head injury. Methods: A 60-year-old woman who suffered a head injury received Korean medicine treatment, including herbal decoctions, acupuncture, electroacupuncture, and physical treatment for 32 days. The response before and after treatment was evaluated using the Manual Muscle Test, the Korean version of the Modified Barthel Index, and walking status. Results: After treatment, the range of the Manual Muscle Test grades of her left lower extremity increased from 1-3 to 2-4. Her score on the Korean version of the Modified Barthel Index improved from 60 to 90. The patient, who was in a wheelchair at the time of admission, walked with a cane upon discharge. Conclusion: This study suggests that intervention with Korean medicine could be one of the therapeutic options for improving hemiparesis after head injury.

• 한국전문물리치료학회지
• /
• 제30권2호
• /
• pp.102-109
• /
• 2023

Background: While efforts have been made to differentiate fall risk in older adults using wearable devices and clinical methodologies, technologies are still infancy. We applied a decision tree (DT) algorithm using inertial measurement unit (IMU) sensor data and clinical measurements to generate high performance classification models of fall risk of older adults. Objects: This study aims to develop a classification model of fall risk using IMU data and clinical measurements in older adults. Methods: Twenty-six older adults were assessed and categorized into high and low fall risk groups. IMU sensor data were obtained while walking from each group, and features were extracted to be used for a DT algorithm with the Gini index (DT1) and the Entropy index (DT2), which generated classification models to differentiate high and low fall risk groups. Model's performance was compared and presented with accuracy, sensitivity, and specificity. Results: Accuracy, sensitivity and specificity were 77.8%, 80.0%, and 66.7%, respectively, for DT1; and 72.2%, 91.7%, and 33.3%, respectively, for DT2. Conclusion: Our results suggest that the fall risk classification using IMU sensor data obtained during gait has potentials to be developed for practical use. Different machine learning techniques involving larger data set should be warranted for future research and development.

• 한국대기환경학회지
• /
• 제2권2호
• /
• pp.1-8
• /
• 1986

To obtain the guidance of plants sensitivity or resistance to $SO_2$ gas, 16 species, 25 varieties of plants were exposed to 0, 0.2, 0.4, 0.7 and 1.5 ppm of $SO_2$ gas in controlled environmental chamber and the visible injury on the plants was observed. Plant sensitivity and/or resistance rankings at each guidance appeared different, based on first injured time, injury degree, and injury index. Only 10 varieties of plant are equal in the ranking at different base. It is concluded that recommended guidance for sensitivity and resistance of plants to $SO_2$ gas are the first injured time and the injury degree, respectively.

• Journal of Acupuncture Research
• /
• 제19권5호
• /
• pp.247-257
• /
• 2002

By process of treatment for a case which diagnosed as spinal cord injury due to spinal arterio-venous malformation and admitted from the 19th, April, 2001 to the 15th, October, 2001, the results are as follows. Methods : The treatment of patient who is diagnosed as spinal cord injury due to spinal arterio-venous malformation by walking abreast of several kinds of oriental medical treatment with rehabilitative therapy. Results : The treatment was taken to the patient upgraded Frankel scale B to D and Cord motor index 61point to 88point.

• 한국산림과학회지
• /
• 제83권4호
• /
• pp.486-497
• /
• 1994

대기오염물질(大氣汚染物質)이 사상공단(沙上工團) 주변(周邊)의 해송림(海松林)에 미치는 영향(影響)을 알아보기 위하여 공단주변(工團周邊)의 해송림(海松林)에서 가시적(可視的)인 피해(被害), 엽내(葉內) 엽록소(葉綠素), 무기성분(無機成分) 및 오염물질(汚染物質) 등(等)을 분석(分析)한 결과(結果)는 다음과 같다. 1. 해송엽(海松葉)의 변색(變色)은 공단(工團) 주변(周邊)의 조사지(調査地)에서 심하게 나타났으며, 엽령(葉齡)이 증가(增加)될수록 심하게 나타났다. 피해도지수(被害度指數)는 공단(工團)에서 가까울수록 높게 나타났다. 2. 엽내(葉內) 수용성유황(水溶性硫黃) 함량(含量)은 전(全) 엽령(葉齡) 모두 공단(工團)에서 가까운 조사지(調査地)에서 높았으며, 전(全) 조사지(調査地)에서 대조구(對照區) 보다 높게 나타났다. 3. 엽록소(葉綠素) a의 함량(含量)은 공단(工團)에서 가까운 조사지(調査地)에서 현저히 감소(減少)되었으며, 엽령(葉齡)이 증가(增加)될수록 높게 나타나 엽록소(葉綠素) a는 대기오염(大氣汚染)에 의해 영향(影響)을 많이 받고 있음을 알 수 있었다. 엽록소(葉綠素) b의 함량(含量)은 많은 조사지(調査地)에서 대조구(對照區)와 차이(差異)가 없었다. 한편 전체(全體) 엽록소(葉綠素)와 엽록소(葉綠素) a와 b의 함량비(含量比)는 엽록소(葉綠素) a의 감소(減少)로 인하여 공단(工團)에서 인접(隣接)한 조사지(調査地)에서 감소(減少)하는 경향(傾向)이 있었다. 4. 엽내(葉內) 인산(燐酸)의 함량(含量)은 엽령(葉齡)이 증가(增加)될수록 공단(工團)으로 부터 더 먼 지역(地域)까지 감소현상(減少現狀)이 나타났으며, 칼슘의 함량(含量)은 전(全) 엽령(葉齡)에서 공단주변(工團周邊) 조사지(調査地)에서 감소(減少)되었다. 5. 피해도지수(被害度指數)와 엽록소(葉綠素) a, 전체(全體) 엽록소(葉綠素), 엽록소(葉綠素) a와 b의 함량비(含量比), 칼슘의 함량간(含量間)에는 부(否)의 상관(相關)이 있었고, 피해도지수(被害度指數)와 수용성유황(水溶性硫黃)의 함량(含量) 간(間)에는 정(定)의 상관(相關)이 있었다. 6. 해송(海松)의 피해도지수(被害度指數), 수용성유황(水溶性硫黃) 함량(含量), 엽록소(葉綠素) 함량(含量), 무기성분(無機成分) 함량(含量) 등에 의해 피해지역(被害地域)을 구분(區分)하기 위해 Cluster분석(分析)을 실시(實施)한 결과(結果), 공단주변(工團周邊) 지역(地域)(1-8 조사지(調査地)), 중간(中間) 지역(地域)(9, 10, 11, 12, 15, 17 조사지(調査地)), 대조구(對照區)를 포함한 비교적(比較的) 먼 지역(地域)(13, 14, 16, 18, 19 조사지(調査地)와 대조구(對照區))으로 크게 3개의 작은 집단(集團)으로 구분(區分)할 수 있었다. 7. 가시적(可視的) 피해(被害)를 받은 해송엽(海松葉)의 횡단면(橫斷面)을 관찰(觀察)한 결과(結果), 엽조직(葉組織)은 엽육세포(葉肉細胞)와 수지구(樹脂溝) 주변(周邊)의 후막세포(厚膜細胞)와 내피층(內皮層)이 부분적(部分的)으로 파괴(破壞)되었다.

• 대한한의학회지
• /
• 제30권3호
• /
• pp.39-50
• /
• 2009

Objective : The aim of this study was to evaluate the effects of Aconiti ciliare tuber on the descending pain and the recovery of locomotor function that results from sciatic crushed nerve injury in rats. Method : In order to assess the effects of the aqueous extract of Aconiti ciliare tuber on the recovery rate of locomotor function, we investigated the walking track analysis, and for the effects on the pain control we investigated brain-derived neurotrophic factor (BDNF) and inducible nitric oxide synthase (iNOS) expression in the sciatic nerve and on the expressions of c-Fos in the ventrolateral periaqueductal gray (vlPAG) region resulting from the sciatic crushed nerve injury in rats. Result : Treatment with Aconiti ciliare tuber significantly enhanced the SFIvalue, enhanced BDNF expression, decreased iNOS expression, and suppressed c-Fos expression. The present results showed that Aconiti ciliare tuber facilitated functional recovery following sciatic crushed nerve injury in rats. The recovery mechanisms of SFI by Aconiti ciliare tuber might be ascribed to the increase of BDNF expression for nerve regeneration and reinnervation and to the suppression of iNOS expression for inhibiting nerve inflammation. Conclusion : In this process it has been shown that Aconiti ciliare tuber can be used for pain control and functional recovery from peripheral nerve injury.

• 척추신경추나의학회지
• /
• 제6권1호
• /
• pp.63-74
• /
• 2011

Objectives: The purpose of this study is to investigate the clinical application of Gamisopunghwalhyeal-tang to three patients traumatic knee joint injury. Methods: Patients are hospitalized at Dept. of Oriental Rehabilitation, Bu-Chun Jaseng Oriental Medicine Hospital, diagnosed as traumatic knee joint injury and treated mainly with herbal medicine ; Gamisopunghwalhyeal-tang. This study was measured by VAS(Visual Analogue Scale) score and walking time and Western Ontario and McMaster Universities(WOMAC) index score. Results: After taking Gamisopunghwalhyeal-tang, the patient's pain was controlled and increased time of walking on floor after treatment. VAS & WOMAC score were decreased. Conclusions: As seen in this three cases of traumatic knee joint injury, Gamisopunghwalhyeal-tang has a positive effect to control pain with traumatic knee joint injury.

• 한방재활의학과학회지
• /
• 제26권3호
• /
• pp.143-151
• /
• 2016

A 57-year-old male patient was diagnosed as Incomplete cervical spinal cord injury and Neurogenic bladder after falling accident and suffered from tetraplegia and urinary retention. The patient was hospitalized and treated with Complex Korean Medical treatment such as acupuncture, electro-acupuncture, bee venom pharmacopuncture and herbal medication for 13 weeks. International Standard for Neurological Classification of Spinal Cord Injury (ISNCSCI) was adopted to evaluate the functional recovery and Korean version of Modified Barthel Index (K-MBI) was adopted to evaluate the recovery of activities of daily living (ADL). After treatment, Total scores of ISNCSCI and K-MBI were improved. Also patient's micturition reflex was recovered and symptoms of neurogenic bladder were improved. This result shows that Korean Medical treatment may be an effective treatment option for spinal cord injury and neurogenic bladder patients. Further clinical studies are needed to clarify the effect of Korean Medical treatment on spinal cord injury.

• 보건행정학회지
• /
• 제23권3호
• /
• pp.233-243
• /
• 2013

Background: This study was conducted to evaluate the individual and community level factors which were influencing the severe injury patients' death and transfer at discharge. Methods: Analysis data is based on Korean National Hospital Discharge In-depth Survey Data released by the Korea Center for Disease Control and Prevention from 2006 to 2008. Study subjects was 11,026 inpatients with of severe injury. For multi-level analysis, socio-demographic characteristics, injury related characteristics, hospitalization related characteristics were used as individual level factors, and socio-environmental characteristics and health care resource characteristics were used as community level factors. Results: As to community level factors affecting mortality of severe injury, the possibility of death was also high in cases of less numbers of surgeons per a population of 100,000 and more number of operation beds. As to community level factors affecting transfer of severe injury, vulnerable areas with higher social deprivation index and low population density had higher possibility of transfer. Conclusion: Both individual level factors and community level factors affected clinical outcomes of treatment for severe injury. In particular, since there happened higher death and transfer of severe injury in socioeconomic and medical vulnerable areas, special efforts for establishing preventive policy and care system for injury in national and area level should be directed toward such areas.