• Title/Summary/Keyword: injection route

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Key Re-distribution Scheme of Dynamic Filtering Utilizing Attack Information for Improving Energy Efficiency in WSNs (무선 센서 네트워크에서 에너지 효율성 향상을 위해 공격정보를 활용한 동적 여과 기법의 키 재분배 기법)

  • Park, Dong-Jin;Cho, Tae-Ho
    • Journal of the Korean Institute of Intelligent Systems
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    • v.26 no.2
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    • pp.113-119
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    • 2016
  • Wireless sensor networks are vulnerable to an adversary due to scarce resources and wireless communication. An adversary can compromise a sensor node and launch a variety of attacks such as false report injection attacks. This attack may cause monetary damage resulting in energy drain by forwarding the false reports and false alarms at the base station. In order to address this problem, a number of en-route filtering schemes has been proposed. Notably, a dynamic en-route filtering scheme can save energy by filtering of the false report. In the key dissemination phase of the existing scheme, the nodes closer to the source node may not have matching keys to detect the false report. Therefore, continuous attacks may result in unnecessary energy wastage. In this paper, we propose a key re-distribution scheme to solve this issue. The proposed scheme early detects the false report injection attacks using initially assigned secret keys in the phase of the key pre-distribution. The experimental results demonstrate the validity of our scheme with energy efficiency of up to 26.63% and filtering capacity up to 15.92% as compared to the existing scheme.

Local Complications after Intramuscular Buttock Injections in Children (소아에서 둔부 근육주사 후 발생한 국소 합병증)

  • Park, Doo-Hyun;Lee, Nam-Hyuk;Kim, Sang-Youn
    • Advances in pediatric surgery
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    • v.4 no.2
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    • pp.137-143
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    • 1998
  • Intramuscular injection(IM) into the gluteal muscles is a common route of medication, but may lead to complications. A retrospective review of 32 patients who required surgical treatment for local complications of buttock injections in children was made at the Taegu Fatima Hospital during a seven-year nine-month period (March 1990 to December 1997). Local complications included acute inflammation, cellulitis and abscess(71.9 %), and fat necrosis(21.9 %), and injection granuloma(6.2 %). Over the half of injections were on the upper and outer quadrant of the buttock, but the other 43.7 % were in the upper and inner or lower and outer quadrant which are considered unsuitable sites for intramuscular injection. The majority of complications developed within fat tissue(90.6 %) rather than within muscle(9.4 %). Two-thirds of the patients were under 2 years of age, this suggests that it is technically difficult to accurately administer IM injections in small children because muscle mass is smaller compared to subcutaneous. In addition subcutaneous fat is more susceptible to chemical irritation. Staph. aureus was the predominant organism, isolated in 84.6 % of the patients with abscesses. Treatment consisted of needle aspiration, incision and drainage, curettage, or surgical excision. In conclusion, the major factor that contributes to complications following IM of the buttock appears to be the inadvertent intrafat rather than of IM injection. Accurate injection into the muscles based on a knowledge of pelvic anatomy as well as the potential complications is necessary to prevent complications.

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Effects of Foot-and-mouth Disease Vaccination Location and Injection Device on the Incidence of Site Lesions in Pork

  • Ko, Eun Young;Jung, Samooel;Jeong, Hyun Kyu;Han, Jeong Hee;Son, Jung Ho
    • Food Science of Animal Resources
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    • v.38 no.3
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    • pp.498-505
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    • 2018
  • This study was aimed to investigate the effects of the type O foot-and-mouse disease vaccine (FMDV) on the incidence of abnormal meat such as granuloma or abscess formation at the injection site in pork and its associated economic losses. At 56 d of age, piglets were inoculated with FMDV by one of three administration routes: N-Neck (a conventional needle-syringe injection into the neck), N-Ham (a conventional needle-syringe injection into the ham), and Non-Neck (injection with a needle-free device into the neck). The injection sites were visually examined for the presence of a granuloma or abscess, and the incidence rate of abnormal meat was calculated. The gross weight of the portion of the pork carcasses condemned because of granuloma or abscess formation was measured and multiplied by the weekly sales price to calculate the total economic losses. After implementation of FMDV, the economic losses were approximately six times higher than before implementation. Granuloma or abscess formation was significantly higher in the N-Neck and Non-Neck groups, in which the vaccine was inoculated into the neck area, than in the N-Ham group (N-Neck and N-Ham vs Non-Neck, p<0.05). These results suggest that the incidence of lesions could be reduced if the ham route was used for vaccination.

Acupuncture and blood borne viral infections: a brief summary

  • Wiwanitkit, Viroj
    • CELLMED
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    • v.2 no.2
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    • pp.13.1-13.3
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    • 2012
  • Blood borne infectious diseases are usually a public concern. The transmissions of many diseases are via blood borne mode. Several activities are related to this transmission such as injection, blood transfusion and transplantation. Also, the acupuncture practice can be a possible route for blood borne infectious disease transmission. In this specific review, the author briefly reviews acupuncture and blood borne viral infections.

Static Filtering Probability Control Method Based on Reliability of Cluster in Sensor Networks (센서 네트워크에서 클러스터 신뢰도 기반 정적 여과 확률 조절 기법)

  • Hur, Suh-Mahn;Seo, Hee-Suk;Lee, Dong-Young;Kim, Tae-Kyung
    • Journal of the Korea Society for Simulation
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    • v.19 no.1
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    • pp.161-171
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    • 2010
  • Sensor Networks are often deployed in unattended environments, thus leaving these networks vulnerable to false data injection attacks in which an adversary injects forged reports into the network through compromised nodes. Such attacks by compromised sensors can cause not only false alarms but also the depletion of the finite amount of energy in a battery powered network. Ye et al. proposed the Statistical En-route Filtering scheme to overcome this threat. In statistical en-route filtering scheme, all the intermediate nodes perform verification as event reports created by center of stimulus node are forwarded to the base station. This paper applies a probabilistic verification method to the Static Statistical En-route Filtering for energy efficiency. It is expected that the farther from the base station an event source is, the higher energy efficiency is achieved.

Immunobiological Studies on Route of Administration of Amygdalin (아미그달린의 투여경로에 따른 면역생물학적 연구)

  • Kim, Joung-Hoon;Kang, Tae-Wook;Park, Chan-Bong;Cha, Kwang-Jae;Ahn, Young-Keun
    • YAKHAK HOEJI
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    • v.40 no.2
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    • pp.202-211
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    • 1996
  • Experiments were performed on male Sprague-Dawley rats to investigate the immunobiological effects on route of administration of amygdalin(AM). Rats were administered orally at 12.5, 25, or 50mg/kg/day of AM or injected wtih 25,50, or 100mg/kg/day of AM intravenously for 2 weeks. Rats were immunized and challenged with sheep red blood cells(SRBC). The results of this study were summarized as follows;(1) In oral administration of AM, body weight gains were significantly increased by 50mg/kg AM as compared with controls, the relative weights of liver and thymus also were significantly increased by 12.5 and 25mg/kg AM. However, 2-mercaptoethanol-resistant hemagglutination titier (2-MER HA), Plaque forming cells (PFC) and rosette forming cells (RFC) were non-dose dependently decreased. Phagocytic activity and delayed-type hypersensitivity (DTH) reaction also were significantly decreased by 50mg/kg AM. (2) In intravenous injection of AM, body weight gains, hemagglutination titer (HA), 2MER-HA, DTH reaction, PFC, RFC and circulating leukocytes were not influenced by AM. However, the relative weights of liver, spleen and thymus were significantly enhanced 100mg/kg AM. These results indicated that oral administration of AM non-dose dependently suppresses humoral and cell-mediated immunity in SD rats, and that intravenous injection of AM is unaffected humoral and cell-mediated immunity, however, the high dose of it significantly enhances phagocytic activity.

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Effect of Corynebacterium parvum on Cellular and Humoral Immune Responses in Mice (Corynebacterium parvum이 마우스의 세포성(細胞性) 및 체액성(體液性) 면역반응(免疫反應)에 미치는 영향(影響))

  • Ha, Tai-You;Suh, Yoon-Suk
    • The Journal of the Korean Society for Microbiology
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    • v.18 no.1
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    • pp.91-98
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    • 1983
  • The effect of subcutanecus injection of Corynebacterium parvum($700{\mu}g$) on cellular and humoral immune responses when given at various time relative to sheep red blood cell(SRBC) sensitization were studied by the evaluation of Arthus, delayed-type hypersensitivity(DTH), rosette forming cell, hemagglutinin and hemolysin reactions. Arthus reactivity(3 hours) developed in control mice and test mice pretreated with C. parvum 8 days prior to intravenous sensitization with SRBC were similar. However, there was slight depression of reactivity when C. parvum was given subcutaneoutly(s.c.) 4 or 2 days prior to SRBC sensitization. Arthus reactivity was significantly depressed when C. parvum was given s.c. either at the same time as, or 2 days later than, antigen. DTH reaction was net depressed significantly when C. parvum was injected 8 or 2 days prior to SRBC sensitization or at the same time as antigen. In contrast DTH was significantly augmented when C. parvum given s.c. 4 days prier to SRBC sensitization. DTH was depressed when C. parvum was given s.c. 2 days after antigen. No significant change occurred in rosette forming percetages of spleen cell when C. parvum was given s.c. 8, 4 or 2 days before SRBC sensitization. In contrast, a significant reduction in percentages of rosette forming cell occurred when C. parvum was given s.c. either at the same time as, or 2 days later than, antigen. Serum hemaggulutinin and hemolysin titers were not significantly affected by subcutaneous injection of C. parvum regardless of time relative to SRBC sensitization. However, mercaptoethanol-resistant hemaggulutinin and hemolysin(IgG) titers were somewhat augmented when C. parvum was given 2 days after antigen. It is concluded from these results that depending on the time and route of inoculation, C. parvum can enhance or depress immune responses in mice, suggesting the time and route of C. parvum inoculation is an important point of concern about clinical use of C. parvum for the treatment of cancer.

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Dispersion Characteristics of Zinc Oxide Nanoparticles in Ionic and Non-ionic Isotonic Solution (이온성 및 비이온성 등장액 용매에서 산화아연나노입자의 분산 특성)

  • Choi, Jonghye;Kim, Hyejin;Park, Kwangsik
    • YAKHAK HOEJI
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    • v.57 no.4
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    • pp.282-288
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    • 2013
  • Zinc oxide nanoparticles (ZnONPs) are widely used in a variety of products and cosmetic products including paper, paints, plastics and sunscreen. However, information on the safety of ZnONPs are not enough and many publications suggest possible toxic effects on environmental and human health. Furthermore, physico-chemical characteristics of nanoparticles makes it hard to test toxicity using the test guidelines of chemicals adopted by regulatory bodies. In this study, stability of ZnONPs was investigated using different types of isotonic solution, which is important in the toxicity study of intravenous route. Precipitation, aggregation, size, zeta potential and morphology of ZnONPs were evaluated with different times and concentrations. Precipitation of ZnONPs were observed in ionic isotonic solution including phosphate-buffered saline, Kreb's-Ringer solution, physiological salt solution and cell culture media of DMEM (Dulbecco's Modified Eagle's Medium) with 10% fetal bovine serum. On the other hand, they were stable without precipitation in non-ionic isotonic solution such as 5% glucose and 2% glycerol, respectively, which are biocompatible for intravenous injection. The average size of ZnONPs in 5% glucose and 2% glycerol was stably maintained, which is less than 30 nm and very similar as that in water dispersion of ZnONPs, provided by the manufacturer. The stability was maintained during the experimental period of 5 days and diluted state up to 15,000 ppm. These data suggest that 5% glucose and 2% glycerol solution can be used for the vehicles of ZnONPs in the toxicity study of intravenous injection route.

A Method to Improve Energy Efficiency Using a Function that Evaluate the Probability of Attempts to Verify a Report at Intermediate Node in USN (USN에서 중간 노드에서의 보고서 검증 시도 확률 평가 함수를 이용한 에너지 효율 향상 기법)

  • Lee, Hyun-Woo;Moon, Soo-Young;Cho, Tae-Ho
    • Journal of the Korea Society for Simulation
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    • v.20 no.4
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    • pp.21-29
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    • 2011
  • Wireless sensor nodes operate in open environments. The deployed sensor nodes are very vulnerable to physical attacks from outside. Attackers compromise some sensor nodes. The compromised nodes by attackers can lead to false data injection into sensor networks. These attacks deplete the limited energy of sensor nodes. Ye et al. proposed the Statistical En-Route Filtering (SEF) as a countermeasure of the attacks. The sensor node in SEF examines the event reports based on certain uniform probability. Thus, the same energies are consumed in both legitimate reports and false reports. In this paper, we propose a method that each node controls the probability of attempts to verify a report to reduce energy consumption of sensor nodes. The probability is determined in consideration of the remaining energy of the node, the number of hops from the node to SINK node, the ratio of false reports. the proposed method can have security which is similar with SEF and consumes lower energy than SEF.

A Study on the Types and Causes of Medication Errors and Related Drugs - by Analyzing AJNs Medication Error 73 Cases - (임상에서의 투약오류원인과 관련 의약품 분석 - AJN에 기고된 Medication Error 기사의 73사례를 중심으로 -)

  • Cho Won Sun
    • Journal of Korean Public Health Nursing
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    • v.16 no.1
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    • pp.176-189
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    • 2002
  • The purpose of this study were to illustrate the various medication error types and causes and identified to related drugs to provide basic data for preventing nurses' medication error by analysing 73 cases of AJN 'medication Error' column(1993, Oct -2000, Nov). Nurses' types of medication error were classified into 7 types. The most frequent error types are wrong medication$(21.9\%)$ and the wrong dose$(21.9\%)$ together. The others are wrong $time(4.1\%)$, $omission(2.7\%)$, mechanical $error(2.7\%)$, incorrect IV $rate(1.4\%)$. wrong route $administration(1.4\%)$ in order. Nurses' causes of medication error were 9 kinds. The most frequent type is confusing between similar drug shape, color, size, name, injection devices and patient's $name(43.9\%)$ and the others are lack of knowledge about $drugs(26.8\%),\; slips(7.3\%),\; miscalculating\;dose(4.9\%)$, incorrect adjusts $devices(4.9\%)$, difficulty to read or illegible decimal $point(4.9\%),$ $abbreviation(2.4\%)$, fatigue with $overwork(2.4\%)$ and no communication with $patient(2.4\%)$ in order. Related drugs with medication error are as follows. - dose unit(IU. minims. mcg/min. mEq) : Heparin. insulin. synthetic calcitonin, some enzymes and hormones, vitamins, some antibiotics, tuberculin injection. MgSO4 injection. nitroglycerin - similar size, color and shape drug : $0.9\%$ N/S and acetic acid $0.25\%$ for irrigation. premixed 2mg lidocaine sol. and $0.9\%$ N/S, gentamycin 20mg/2mL for children and 80mg/2mL for adult, dextroamphetamine 5mg and 10mg capsule. sedatives chloral hydrate 250mg/5mL and 500mg/5mL - similar name :Aredia(pamidronate disodium) and Adriamycin(doxorubicin), Lamictal (lamotrigine) and Lamisil 250mg. Elderpryl and enalapril, cefotaxime and cefoxitin, carboplatin and cisplatin, sumatriptan and zolmitriptan, Celebrex and Celexa, Humulin and Humalog, Percodan and Percocet, Diabeta and Diabinese, Epivir and Retrovir, Xanax(alprazolam) and Zantac(ranitidine) - decimal point : low molecular weight warfarin, methotrexate - unfamiliar drug uses of familiar drug ; methotrexate. droperidol, imipramine, propranolol - number of drug name(misleading chemical name) : 6-thioguanine, 6-mercaptopurine, 5-fluorouracil - type of administration route : Oxycodone(OxyContin). - administration time : acarbose(Precose). - injection way (Z-track method): hydroxyzine - epidural cathether : LMWHs(enoxaparin, dalteparin), - ADD Vantage self contained delivery system : ceftriaxone(Rocephin)

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