• Title/Summary/Keyword: injection duration

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Comprehensive Korean Medicine Treatment for Benign Essential Blepharospasm in a Patient Responding Poorly to Botulinum Toxin Treatment

  • Ha, Seojung;Kim, Sung A;Lee, Suji;Choi, Sungwoon;Lee, Sanghoon
    • Journal of Acupuncture Research
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    • v.39 no.1
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    • pp.49-52
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    • 2022
  • Benign essential blepharospasm (BEB) is a condition/disease which involves involuntary muscle contractions causing the eye to repetitively close, making it impossible for the patient to perform daily activities. This study reports Korean medicine treatment of a rare case BEB in a 34-year-old male patient whose symptoms showed minimal improvement following botulinum toxin injection (the standard treatment). Acupuncture, pharmacopuncture, and herbal medicine treatment for 11 days resulted in clinical improvement for all symptoms as assessed by using the Jankovic Rating Scale, Blepharospasm Disability Index, numerical rating scale, duration of spasms lasting more than 1 hour per day, and number of spasms lasting less than 1 minute per day. This case report suggests that comprehensive Korean medicine treatment could be a treatment option for BEB in patients who do not respond well to botulinum toxin injection.

Intralesional Injection of Autologous Platelet-Rich Plasma as an Effective Regeneration Therapy: A Case Report of Chronic Wagner Grade 2 Diabetic Foot Ulcer (증례 보고: 병변 내 자가 혈소판풍부혈장 주사로 효과적으로 재생된 만성화된 Wagner Grade 2 당뇨발 궤양 1예)

  • Moon Hee, Kim
    • Journal of Korean Foot and Ankle Society
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    • v.26 no.4
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    • pp.187-191
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    • 2022
  • The author experienced a case of autologous platelet-rich plasma (PRP) affecting the recovery of a chronic neuropathic diabetic foot ulcer combined with infection. A 65-year-aged male with uncontrolled diabetes presented with a Wagner grade 2 diabetic foot ulcer on his left forefoot of more than 2 weeks duration. Osteomyelitis, gangrene, and ischemia requiring acute intervention were absent. Although infection was controlled to a moderate degree, wound healing was unsatisfactory following surgical debridement and simple dressing. Therefore, intralesional autologous PRP injection was performed 5 times as an adjuvant regeneration therapy, and the recalcitrant ulcer healed in 3 months. Intralesional PRP injections are worthwhile as they promote wound regeneration, are evidence-based, safe, and can be easily performed in ambulatory care facilities.

A Study on the Combustion and Smoke Emission Characteristics of the Natural Aspiration Type Diesel Engine (자연흡기식 디젤 기관의 연소와 매연 배출 특성에 관한 실험적 연구)

  • 정우인;박찬국
    • Transactions of the Korean Society of Automotive Engineers
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    • v.5 no.4
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    • pp.70-83
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    • 1997
  • We made a selection of engine operating conditions in the natural aspiration type diesel engine as load and speed. The effects on the power, smoke emission and cylinder pressure characteristics of these variations in operating conditions were observed experimentally. Also, the smoke emission was predicted by using the Arrhenius equation and empirical equation of the smoke emission was made. At the same time, the correlations, between the combustion and smoke emission characteristic were examined. From the above results, it is clear that to prevent power dropping and to decrease exhaust fume whin the conditions are changed, one should improve the intake system. To do this, the best way is to lower the air-fuel mixing ratio. We found that the parameters of the indicated mean effective pressure, maximum pressure and its location and combustion duration, etc. change the motion in accordance with the conditions described above. Also, we found that the variation of the pressure cycle comes from an amplified variation of the early part of process. From the analysis of comparing combustion and exhaust fume, the exhaust fume is produced at the latter time of combustion and decreased when the combustion ratio is higher. Also, we developed a special formula which can predict the exhaust fume value according to the engine load and speed.

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A Study on the Event Processing for Electronic Control (전자제어의 Event 처리방법에 관한 연구)

  • 이종승;이중순;정성식;하종률
    • Transactions of the Korean Society of Automotive Engineers
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    • v.6 no.3
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    • pp.115-122
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    • 1998
  • For digital engine control timings, such as ignition, are based on the crank shaft angle. Therefore, it is very important that the angle of the crank shaft can be detected with accuracy for optimal ignition timing. Sequential multi-point injection(MPI) systems that have independent injection events for each cylinder, are used to inject an accurate quantity of fuel, and to cope with varying engine status promptly. In this study the distributorless ignition timing. A crankshaft position sensor has been installed such that it generates a number of pulses per crankshaft revolution to permit accurate detection of the crank shaft angle. An event detecting algorithm has been developed, which detects the crank shaft pulses generated by the position sensor, and the software outputs the required control signals at given crank angle values. We clarified that the hardware method is the best way to increase the performance of the control system, because the event detecting duration T(1+2)max becomes zero.

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Impinging Atomization of Intermittent Gasoline Sprays (간헐 가솔린 분무의 충돌에 의한 미립화 촉진)

  • 원영호;임치락
    • Transactions of the Korean Society of Automotive Engineers
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    • v.6 no.5
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    • pp.174-181
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    • 1998
  • Experimental and analytical studies are presented to characterize the break-up mechanism and atomization processes of the intermittent- impinging-type nozzle. Gasoline jets passing through the circular nozzle with the outlet diameter of 0.4mm and the injection duration of 10ms are impinged on each other. The impingement of fuel jets forms a thin liquid sheet, and the break-up of the liquid sheet produces liquid ligaments and droplets subsequently. The shape of liquid sheets was visualized at various impinging velocities and angles using the planer laser induced fluorescence (PLIF) technique. Based on the Kelvin-Helmholtz wave instability theory, the break-up length of liquid sheets and the droplet diameter are obtained by the theoretical analysis of the sheet disintegration. The mean diameter of droplet is also estimated analytically using the liquid sheet thickness at the edge and the wavelength of the fastest growing wave. The present results indicate that the theoretical results are favorably agreed with the experimental results. The size of droplets decreases after the impingement as the impinging angle or the injection pressure increase. The increment of the injection pressure is more effective than the increment of the impinging angle to reduce the size of droplets.

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A Study on the Piezo Injector Control Algorithm for CRDI Diesel Engines (커먼레일 디젤 엔진용 피에조 인젝터 제어에 관한 연구)

  • Oh, Byoung-Gul;Oh, Seung-Suk;Park, Yeong-Seop;Lee, Kang-Yoon;SunWoo, Myoung-Ho
    • Journal of the Korean Society for Precision Engineering
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    • v.26 no.2
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    • pp.54-62
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    • 2009
  • The purpose of this study is to develop a piezo injector driver for common-rail direct injection diesel engines. In this research, we analyzed the electrical and mechanical characteristics of the piezo actuator through experiments. Current flow and charging voltage of the piezo injector are controlled by the PWM signal of variable duty ratio in order to realize both fast response and low peak current. The optimal switching duty ratio was designed by modeling and analyzing of the piezo driver circuit. In order to avoid resonance and unacceptably long settling time, appropriate frequency range of the PWM signal was derived based on the driver circuit model. The developed injector driver was validated by experiments under various fuel rail pressure, injection duration, and charging voltage.

Comparison of Suprascapular Nerve Block and Shoulder Joint Injection for Treatment of Frozen Shoulder (견구축증(Frozen Shoulder)에서 견갑상신경차단과 견관절강내 주사의 통증 치료 효과)

  • Jeong, Hyeon-Gyoo;Lee, Sang-Gon
    • The Korean Journal of Pain
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    • v.11 no.2
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    • pp.226-229
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    • 1998
  • Background: Treatment for frozen shoulder is various and difficult. It is important for pain clinicians to plan more effective and simpler treatment modalities. Pain clinicians have done suprascapular nerve block(SSNB) for treatment of frozen shoulder, but the effectiveness of treatment has been unsatisfactory. Shoulder joint injection(SJI) using local anesthetics and steroid mixture is a relatively simple procedure. This study was performed to compare therapeutic effects of SSNB and SJI in frozen shoulder. Methods: Eighty patients suffering from frozen shoulder were randomly divided into two groups. Group 1 had been treated with SSNB and physiotherapy for 3 weeks. Group 2 had been treated with SJI and physiotherapy for the same duration. Pain scores and treatment results were compared and analyzed at the time of 2 months after treatment started. Results: The VAS scores after SJI were lower than those of SSNB. Therapeutic results according to Haggart's classifications were significantly effective in group 2. Conclusion: These results show that SJI is more effective than SSNB for treatment of frozen shoulder.

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Changes in Plasma Lipid Pattern in Streptozotocin-Induced Diabetic Rats: A Time Course Study (스트렙토토신-당뇨쥐의 유병기간에 따른 혈중지질패턴의 경시적 변화)

  • 이수자
    • Journal of Nutrition and Health
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    • v.32 no.7
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    • pp.767-774
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    • 1999
  • This study was carrid out to examine a part of the mechanism for the etiology of diabetic complications. Thirty normal and forty streptozotocin(STZ)-induced diabetic rats were used as the animal models. Animals were sacrificed at the time points of 3 days, 1, 2, 4 and 6 weeks after STZ-injection and time course in body weight and organ weight, the levels of blood glucose, plasma lipid patterns, and atherogenic index were measured during 6 weeks. The STZ-diabetic animals showed 63% survival rate and fsting blood glucose levels of the diabetic animals measured in the range of 230-410mg/dL during the experimental period. The body weigh of diabetic animals decreased significantly throughout the experimental period and the relative weights of organs to body weight were significantly higher than the normal control ones. The enlargement of the kidney in the diabetic animals was especially remarkable. Plasma triglyceride concentration in diabetic rats substancially increased from the first week of onset of diabetes mellitus and maintained higher levels than the control ones throughout the whole experimental period. The plasma total cholesterol level and atherogenic index in the diabetic rats were significantly higher than the normal ones from the third day after STZ injection and showed a gradual increase with the duration of the disease. Throughout the experiment, the diabetic rats consistently showed a slightly lower HDL-cholesterol level compared to the normal animals. From the results of this study, it appears that the significant changes in blood lipid pattern in STZ-diabetic animals start from the first week after STZ injection.

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A Clinical Study of Trigger Point by Blocking Methods (유발점 차단에 의한 임상적 연구)

  • Hur, Yung-Gu
    • Journal of Korean Physical Therapy Science
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    • v.4 no.2
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    • pp.383-390
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    • 1997
  • The purpose of this study is the evaluation of the degree of post injection soreness, symptom duration, factor and autonomic symptoms after trigger point injection in patients with trigger points. We devided the subjects of the study into four groups Such as, only dry needling, needle-TENS, with massage-stretch, massage-stretch only, including 100 patients, and measured the visual analog scale before treatment and after treatment. Before treatment, The VAS mean scores were $6.2{\pm}1.03$ in needle-TENS with massage-stretch group ; $6.2{\pm}1.75$ in needdle-TENS group, and $6.3{\pm}1.85$ in dry needling group, and $6.8{\pm}1.03$ in massage-stretch group. In post injection 3rd day, The VAS mean score were $0.9{\pm}1.78$ in needling-TENS with massage-stretch group, $1.1{\pm}1.52$ in needling-TENS group, $1.7{\pm}1.10$ in dry needling group, and $3.9{\pm}3.01$ in massage-stretch group. As for a causative factor of activities for trigger were overload with 37.0%, overwork with 35.0% and fatigue with 13.0%. Symptoms for trigger were tenderness with 28.0%, numbness and tingling with 24.0%. ROM limit with 17.0% and tightness with 17.0%. As a result, needling-TENS with massage-stretch group showed less soreness and effect than other group.

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Anti-Inflammatory Effects of 15Hz Electroacupuncture on the Carrageenan-Injected Rat (Carrageenan 유발염증에 대한 15Hz 전침의 효과에 대한 연구)

  • Han, You-jin;Lee, Yong-tae;Jang, Kyung-jeon
    • Journal of Acupuncture Research
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    • v.20 no.3
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    • pp.166-176
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    • 2003
  • Objective : The aim of this study is to investigate the anti-inflammatory effects of 15Hz electroacupuncture(EA) on carrageenan-injected rats. Inflammation was induced by an intraplantar injection of 1% carrageenan into the right hind paw. Methods : Bilateral EA stimulation with 15 Hz were delivered at those acupoints corresponding to Zusanli and Sanyinjiao in man via the needles for a total of 30 min duration in carrageenan-injected rats. Results: The developing edema was measured 30 minutes interval afer carrageenan injection and 15 Hz EA stimulation presented significant edema inhibition. Three hours after carrageenan injection, prostaglandin $E_2(PGE_2)$ and nitric oxide(NO) levels were measured. The 15Hz EA stimulation significantly inhibited $PGE_2$ and NO production in the right paw. The pro-inflammatory mRNA expression such as cyclooxygenases(COX)-2 and interleukin(IL)-$1{\beta}$ were slightly down-regulated by EA stimulation. The number of COX-2, IL-$1{\beta}$, tumor necrosis factor-${\alpha}$ immunoreactive cells were abundantly observed in paw edema. But these cells were decreased in nmber according to anti-edema effect of 15Hz EA. Conclusions: These results indicate that 15Hz EA stimulation have an alleviation action against carrageenan-induced edema and local inflammation.

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