• International journal of steel structures
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• v.18 no.4
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• pp.1470-1481
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• 2018

Building-level response to post-earthquake fire hazards in steel buildings has been assessed using primarily two-dimensional analyses of the lateral force resisting system. This approach may not adequately consider potential vulnerabilities in the gravity framing system. For this reason, three-dimensional (3D) finite element models of a 10-story case study building with perimeter moment resisting frames were developed to analyze post-earthquake fire events and better understand building response. Earthquakes are simulated using ground motion time histories, while Eurocode parametric time-temperature curves are used to represent compartment fires. Incremental dynamic analysis and incremental fire analysis procedures capture a range of hazard intensities. Findings show that the structural response due to earthquake and fire hazards are somewhat decoupled from one another. Regardless of the level of plastic hinging present in the moment framing system due to a seismic event, gravity column failure is the initiating failure mode in a fire event.

• Nuclear Engineering and Technology
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• v.44 no.4
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• pp.393-404
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• 2012

After the Fukushima nuclear accident in 2011, there has been increasing concern regarding severe accidents in nuclear facilities. Severe accident scenarios are difficult for operators to monitor and identify. Therefore, accurate prediction of a severe accident is important in order to manage it appropriately in the unfavorable conditions. In this study, artificial intelligence (AI) techniques, such as support vector classification (SVC), probabilistic neural network (PNN), group method of data handling (GMDH), and fuzzy neural network (FNN), were used to monitor the major transient scenarios of a severe accident caused by three different initiating events, the hot-leg loss of coolant accident (LOCA), the cold-leg LOCA, and the steam generator tube rupture in pressurized water reactors (PWRs). The SVC and PNN models were used for the event classification. The GMDH and FNN models were employed to accurately predict the important timing representing severe accident scenarios. In addition, in order to verify the proposed algorithm, data from a number of numerical simulations were required in order to train the AI techniques due to the shortage of real LOCA data. The data was acquired by performing simulations using the MAAP4 code. The prediction accuracy of the three types of initiating events was sufficiently high to predict severe accident scenarios. Therefore, the AI techniques can be applied successfully in the identification and monitoring of severe accident scenarios in real PWRs.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.18 no.spc
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• pp.63-74
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• 2020

The operational safety assessment is an important part of a safety case for the deep geological repository of spent fuels. It consists of different stages such as the identification of initiating events, event tree analysis, fault tree analysis, and evaluation of exposure doses to the public and radiation workers. This study develops a probabilistic safety assessment method for the operational safety assessment and establishes an assessment framework. For the event and fault tree analyses, we propose the advanced information management system for probabilistic safety assessment (AIMS-PSA Manager). In addition, we propose the Radiological Safety Analysis Computer (RSAC) program to evaluate exposure doses to the public and radiation workers. Furthermore, we check the applicability of the assessment framework with respect to drop accidents of a spent fuel assembly arising out of crane failure, at the surface facility of the KRS⁺ (KAERI Reference disposal System for SNFs). The methods and tools established through this study can be used for the development of a safety case for the KRS⁺ system as well as for the design modification and the operational safety assessment of the KRS⁺ system.

• Nuclear Engineering and Technology
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• v.44 no.3
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• pp.311-322
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• 2012

Since the crisis at the Fukushima plants, severe accident progression during a station blackout accident in nuclear power plants is recognized as a very important area for accident management and emergency planning. The purpose of this study is to investigate the comparative characteristics of anticipated severe accident progression among the three typical types of nuclear reactors. A station blackout scenario, where all off-site power is lost and the diesel generators fail, is simulated as an initiating event of a severe accident sequence. In this study a comparative analysis was performed for typical pressurized water reactor (PWR), boiling water reactor (BWR), and pressurized heavy water reactor (PHWR). The study includes the summarization of design differences that would impact severe accident progressions, thermal hydraulic/severe accident phenomenological analysis during a station blackout initiated-severe accident; and an investigation of the core damage process, both within the reactor vessel before it fails and in the containment afterwards, and the resultant impact on the containment.

• Journal of the Korean Home Economics Association
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• v.39 no.7
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• pp.71-84
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• 2001

The purpose of this study was to investigate the development of preschoolers'narrative competence. The subject were 60 preschoolers aged 3 through 5 years who were enrolled in the day care center All the subjects were asked to produce a new story. All the story children toad were recorded on audiotape. The data were analyzed Qualitatively and quantitatively using content analysis and the statistical package for Social Science 9.0. The main results of this study were as follows. 1) Significant age difference was observed in preschooler's narrative structure. Older children produced structurally more complex stories containing setting, character, initiating event, attempt and consequence than younger children. 2) Significant age difference was observed in preschooler's narrative length. Older children used significantly more words and sentence when they produced stories than younger children.3) Preschooler'narrative structure was significantly correlated with narrative length.

• Molecules and Cells
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• v.39 no.1
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• pp.72-76
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• 2016

Cell death pathways such as apoptosis can be activated in response to oxidative stress, enabling the disposal of damaged cells. In contrast, controlled intracellular redox events are proposed to be a significant event during apoptosis signaling, regardless of the initiating stimulus. In this scenario oxidants act as second messengers, mediating the post-translational modification of specific regulatory proteins. The exact mechanism of this signaling is unclear, but increased understanding offers the potential to promote or inhibit apoptosis through modulating the redox environment of cells. Peroxiredoxins are thiol peroxidases that remove hydroperoxides, and are also emerging as important players in cellular redox signaling. This review discusses the potential role of peroxiredoxins in the regulation of apoptosis, and also their ability to act as biomarkers of redox changes during the initiation and progression of cell death.

• Nuclear Engineering and Technology
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• v.45 no.4
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• pp.459-468
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• 2013

During a station blackout (SBO), the initiating event is a loss of Class IV and Class III power, causing the loss of the pumps, used in systems such as the primary heat transporting system (PHTS), moderator cooling, shield cooling, steam generator feed water, and re-circulating cooling water. The reference case of the SBO case does not credit any of these active heat sinks, but only relies on the passive heat sinks, particularly the initial water inventories of the PHTS, moderator, steam generator secondary side, end shields, and reactor vault. The reference analysis is followed by a series of sensitivity cases assuming certain system availabilities, in order to assess their mitigating effects. This paper also establishes the strategies to mitigate SBO accidents. Current studies and strategies use the computer code of the Integrated Severe Accident Analysis Code (ISAAC) for Wolsong plants. The analysis results demonstrate that appropriate strategies to mitigate SBO accidents are established and, in addition, the symptoms of the SBO processes are understood.

• Archives of Craniofacial Surgery
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• v.22 no.5
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• pp.276-279
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• 2021

A 65-year-old woman presented with a solid mass on the right temporal area. The mass had grown for over 2 years without any initiating event of trauma or inflammation. Before excision, the patient went through a computed tomography scan, revealing a calcified mass without bony connection. Under general anesthesia, an excisional biopsy was performed. Microscopic examination confirmed a diagnosis of soft tissue osteoma. Soft tissue osteoma is rare, especially in the head and neck region. Osteomas in the temporal region have not been reported yet. Due to its rarity, osteoma might be misdiagnosed as another soft tissue or bone origin tumor. Its treatment of choice is simple excision. In this review, we present an unusual clinical form of soft tissue osteoma.

• Nuclear Engineering and Technology
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• v.53 no.10
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• pp.3256-3263
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• 2021

The main steam line break accident is an essential initiating event of the pressurized water reactor. In present work, the fuzzy set theory and the signal-based fault detection method has been used to detect the occurrence and diagnosis of the location and break area for the small scale MSLB. The models are validated by the AP1000 accident simulator based on MAAP5. From the test results it can be seen that the proposed approach has a rapid and proper response on accident detection and location diagnosis. The method proposed to evaluate the break area shows good performances for small scale MSLB with the relative deviation within ±3%.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.71.1-71.1
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• 2003

We show that Cdc6, an essential initiation factor for DNA replication, undergoes caspase-3-mediated cleavage in the early stages of apoptosis in HeLa cells and SK-HEP-1 cells induced by etoposide, paclitaxel, ginsenoside Rh2, or TRAIL. The cleavage occurs at the SEVD$\^$442//G motif and generates an N-terminal truncated Cdc6 fragment (p49-tCdc6) that lacks the carboxy-terminal nuclear export sequence (NES). Cdc6 is known to be phosphorylated by cyclin A-Cyclin A-dependent kinase 2 (Cdk2), an event that promotes its exit from the nucleus and probably blocks it from initiating inappropriate DNA replication. (omitted)