• Title/Summary/Keyword: ingestion

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Elemental Analysis of herbal medicine, Foundry Air and Hair for the Study of Human Surroundings (인체 환경 연구를 위한 한약재, 작업장 공기 및 모발의 원소분석)

  • 강상훈;이상순;조승연;정용삼
    • Journal of Environmental Health Sciences
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    • v.28 no.3
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    • pp.64-71
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    • 2002
  • Hair provides important information about the body's mineral status. Therefore, we have studied the trace elemental distribution in human hair under different inhalation and ingestion environment using neutron activation analysis (NAA). NAA is a powerful analytical method which can be used successfully to determine trace elements in environmental and biological materials. Total diet and six different herbal medicine were analysed to study ingestion environment. Airborne dust in foundry was analysed and compared with outdoor dust to study inhalation environment. Human hairs of common person, herbal medicine taker and foundry worker were analysed to estimate the trace elemental distribution of people under different inhalation and ingestion environment. Analytical results show that herbal medicines contain higher micronutrients such as Ca, Mg, Mn and Cu that total diet and airborne dust in foundry has high Cr. The concentration of Ca, Mg and Mn in hair of herbal medicine taker is two times higher than in hair of common person and Cr con-centration in hair of foundry worker is about three times higher than in hair of common person. These results show that NAA can be used importantly to monitor human health through biological and environmental samples.

A Case of Cantharidin Poisoning after the Ingestion of Herbal Medicine (한약복용 후 발생한 칸타리딘 중독 1례)

  • Ji Ho Jin;Kim Hyun;Kim Sun Hyu;Oh Sung Bum;Moon Joong Bum;Lee Kang Hyun;Hwang Sung Oh
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.1
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    • pp.56-59
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    • 2005
  • Blister beetles produce cantharidin, which is toxic to people and animals. Cantharidin has been believed to be an aphrodisiac and an abortifacient based on its tendency to cause marked irritation to the genitourinary system leading to priapism in men and pelvic congestion in women for many years. Cantharidin was used by oriental traditional medicine for more than 2000 years. Typical signs related to cantharidin ingestion are gastrointestinal tract and urinary tract irritation, endotoxemia, shock and myocardial dysfunction. Cantharidin is a severe irritant to epithelial linings (gastrointestinal tract, urinary tract, and skin) and develop systemic inflammatory response syndrome. We report a case of corrosive esophagogastritis and acute renal failure by ingestion of cantharidin.

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Diagnostic Radioopacity in Chloroform Ingestion -A Case Report- (방사선 비투과성 클로로포름 음독 1례)

  • Lee Sung Woo;Choi Sung Hyuk;Hong Yun Sik;Kim Su Jin;Moon Sung Woo;Moon Jun Dong;Jung Sang Hyun;Park Jong Su
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.1
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    • pp.48-51
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    • 2005
  • Diagostic imaging can help in management of toxicologic emergencies. We report a patient who presented to the emergency department with coma and suppressed respiration after ingestion of unknown substance. We documented chloroform with radiopaque material in bowel on abdominal radiograph. We used activated charcoal and laxative to decontaminate bowel. Hepatotoxicity occurred on 3rd admission day and elevation of liver enzyme reached peak level on 5th admission day. The patient received hemoperfusion, N-acetylsystein and supportive cares. The patient was improved from hepatic dysfunction and discharged without complication on 11th admission day. Radiograph in toxicology may confirm a diagnosis and assist in therapeutic intervention.

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Broadband Noise Analysis of Horizontal Axis Wind Turbines Including Low Frequency Noise (수평축 풍력발전기의 저주파소음을 포함한 광대역소음 해석에 관한 연구)

  • Him, Hyun-Jung;Kim, Ho-Geun;Lee, Soo-Gab
    • New & Renewable Energy
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    • v.3 no.3
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    • pp.45-53
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    • 2007
  • This paper demonstrates a computational method in predicting aerodynamic noise generated from wind turbines. Low frequency noise due to displacement of fluid and leading fluctuation, according to the blade passing motion, is modelled on monopole and dipole sources. They are predicted by Farassat 1A equation. Airfoil self noise and turbulence ingestion noise are modelled upon quadrupole sources and are predicted by semi-empirical formulas composed on the groundwork of Brooks et al. and Lowson. Aerodynamic flow in the vicinity of the blade should be obtained first, while noise source modelling need them as numerical inputs. Vortex Lattice Method(VLM) is used to compute aerodynamic conditions near blade. In the use of program X-foil [M.Drela] boundary layer characteristics are calculated to obtain airfoil self noise. Wind turbine blades are divided into spanwise unit panels, and each panel is considered as an independent source. Retarded time is considered, not only in low frequency noise but also In turbulence ingestion noise and airfoil self noise prediction. Numerical modelling is validated with measurement from NREL [AOC15/50 Turbine) and ETSU [Markham's VS45] wind turbine noise measurements.

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INGESTION OF ORTHODONTIC ANCHORAGE SCREWS: AN EXPERIMENTAL STUDY IN DOGS (교정 고정원 스크류의 위장관으로 섭취시 예후에 대한 실험적 평가)

  • Li, Jing-Xu;Choi, Byung-Ho;Kim, Yeon-Hwan;Kim, Han-Sung;Ko, Chang-Yong
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.2
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    • pp.121-123
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    • 2007
  • Foreign bodies with a sharp edge which are accidentally swallowed are likely to become lodged in the stomach. An animal study was undertaken to determine the outcome of orthodontic anchorage screw ingestion. The radiographic findings of ten Mongolian dogs that ingested a total of 10 orthodontic anchorage screws and 10 reamers (both a screw and a reamer per dog) were evaluated. The study showed that all orthodontic anchorage screws and reamers reaching the stomach spontaneously passed, with the exception of two reamers. Further investigation of clinical cases might be necessary to determine whether the results of our animal study are in accordance with clinical findings.

A Case of Acute Intoxication with Glyphosate and Oxyfluorfen Containing Powder Herbicide ($Daejangun^{(R)}$) (Oxyfluoren이 함유된 입제 glyphosate 제초제(대장군) 급성 중독 1예)

  • Lee Seung Hee;Yi Kum Ho;Yoo Sung-Soo;Roh Heung-Keun
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.2
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    • pp.110-113
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    • 2005
  • Glyphosate containing herbicides are an alternative to paraquat and have been widely used with increasing frequency in suicide attempts throughout Asia. It is an organophosphorus compound that is not a cholinesterase inhibitor. Daejangun powder consists of glyphosate ammonium, surfactant and another herbicide, oxyfluorfen. A 60-year-old man ingested about 300 g of Daejangun powder with 500 ml of water in a suicide attempt. He was brought to emergency room 6 hours after the ingestion and showed severe metabolic acidosis (pH 6.75), marked leukocytosis (WBC 35,800/$mm^3$), hypoglycemia (glucose 13 mg/dL) and increased liver enzymes (AST/ALT 1,683/418 IU/L). Later he developed aspiration pneumonia, acute renal failure and hyperchloremic acidosis. Upper gastrointestinal endoscopy which performed 5 days after the ingestion revealed corrosive injuries (grade 1) in both esophagus and stomach. However, intensive treatment with supportive measures improved the abnormal findings almost completely 4 weeks after the ingestion.

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A Case of Serious Caustic Injury after Ingestion of Hydrochloric Acid (염산으로 인한 중대한 부식성 손상 1례)

  • Park Hyun-Joo;Yi Hyeon-Gyu;Kim Pum-Soo;Roh Hyung-Keun
    • Journal of The Korean Society of Clinical Toxicology
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    • v.2 no.1
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    • pp.58-62
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    • 2004
  • Acid ingestion can cause not only caustic injury on esophagus and stomach but also fatal outcome through systemic complications. We report the case of a patient who died early after severe caustic injury with strong acid. A 38-year-old man who ingested about 400ml of hydrochloric acid of unknown concentration was transferred to our hospital from a private clinic, in which he was managed with gastric irrigation through a nasogastric tube. He was complaining dyspnea and abdominal pain. Physical examination demonstrated tenderness and rebound tenderness on epigastric region. Severe metabolic acidosis and leukocytosis were noted. Radiological findings suggested perforation of gastrointestinal tract, although the physical signs were not typical. Endoscopy revealed caustic injuries of grade I on esophagus and of grade Ⅲ on stomach, which indicate more severe injury on the stomach than on the esophagus. Exploratory surgery was recommended but unfortunately not permitted by his family. Despite intensive measures, his vital signs deteriorated rapidly and he died 50 hours after the ingestion.

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Ingestion Toxicity of Fipronil on Reticulitermes speratus kyushuensis (Isoptera: Rhinotermitidae) and Its Applicability as A Termite Bait

  • Kim, Si Hyun;Chung, Yong Jae
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.2
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    • pp.159-167
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    • 2017
  • Historical wooden buildings in Korea are being damaged by Reticulitermes speratus kyushuensis Morimoto, a type of subterranean termite, and the scale of this damage is increasing gradually because of global warming. This study evaluated the ingestion toxicity of the phenylpyrazole insecticide fipronil to R. s. kyushuensis and its applicability as termite bait with the aim of controlling termite colonies more efficiently. An ingestion toxicity assessment was conducted and the $LT_{50}$ was determined to be 4.43 day at concentrations of 10 ppm, indicating a slow-acting effect; therefore, 10 ppm was selected as an appropriate dose. A field applicability assessment was conducted in which the number of foraging workers and the rate at which the termites fed decreased 2 weeks after baiting, and termite colony activity was no longer apparent after 4 weeks demonstrating the efficacy of fipronil at eliminating colonies. Taken together, these results, indicate that low-dose fipronil eliminated R. s. kyushuensis colonies faster than insect growth regulators; therefore, it is expected to be useful when trying to conserve historical wooden buildings.

Toxocariasis and Ingestion of Raw Cow Liver in Patients with Eosinophilia

  • Choi, Dong-Il;Lim, Jae-Hoon;Choi, Dong-Chull;Paik, Seung-Woon;Kim, Sun-Hee;Huh, Sun
    • Parasites, Hosts and Diseases
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    • v.46 no.3
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    • pp.139-143
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    • 2008
  • Ingestion of raw animal liver has been suggested as a possible mode of infection of human toxocariasis, We evaluated the relationship between toxocariasis and the ingestion of raw meat in patients with eosinophilia of unknown etiology. The study population consisted of 120 patients presenting with peripheral blood eosinophilia (> $500\;cells/{\mu}l$ or > 10% of the white blood cell count). They were divided into 2 groups: 104 seropositive patients based on a Toxocara excretory-secretory IgG ELISA and 16 seronegative patients. While 25.0% of seronegative patients had a recent history of eating raw cow liver, 87.5% of seropositive patients had this history. Multivariate statistical analysis showed that a recent history of eating raw cow liver was related to an increased risk of toxocariasis. Collectively, it is proposed that raw cow liver is a significant infection source of toxocariasis in the patients with eosinophilia of unknown etiology.

Risk factors predicting development of complications in 72 dogs with esophageal foreign bodies

  • Shin, Bohye;Kim, Hakhyun;Chang, Dongwoo;Kang, Ji-Houn;Kang, Byeong-Teck;Yang, Mhan-pyo
    • Korean Journal of Veterinary Research
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    • v.59 no.1
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    • pp.25-31
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    • 2019
  • The aim of this study was to determine predictive risk factors implicated in complications in dogs with esophageal foreign bodies. Medical records of 72 dogs diagnosed with esophageal foreign bodies by endoscopy were reviewed retrospectively. Factors analyzed included age; breed; gender; body weight, location, dimension, and type of foreign body; and duration of impaction. To identify risk factors associated with complications after foreign body ingestion, categorical variables were analyzed using the chisquare or Fisher's exact tests and multivariate analysis, as appropriate. Complications secondary to esophageal foreign body ingestion included megaesophagus, esophagitis, perforation, laceration, diverticulum, and pleuritis. Univariate analysis revealed that the location and duration of impaction after foreign body ingestion were associated with an increased risk of esophageal laceration and perforation. Multivariate analysis showed that age, duration of impaction, and foreign body dimension were significant independent risk factors associated with the development of complications in dogs with esophageal foreign bodies. In conclusion, these results showed that longer duration of impaction and larger foreign body dimensions may increase the risks of esophageal laceration, perforation, and plueritis in dogs.