• 제목/요약/키워드: infection process

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침입종 미국실새삼(Cuscuta pentagona Engelm.)의 기주식물 선호도, 기생부위 및 위해가능성 (Host plant preference, parasitic site and risk possibility of Cuscuta pentagona Engelm, invasive plant in Korea)

  • 정영호;이재근;이수인;이승연;장래하;이승혁;조규태;유영한
    • 한국환경생태학회지
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    • 제31권3호
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    • pp.287-296
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    • 2017
  • 이 연구는 완전 기생성 침입종인 미국실새삼(Cuscuta pentagona)의 기주선호도와 기생부위를 야외현장과 기생유도 실험 통하여 확인하여 이들 식물의 기주다양성을 알아보고 잠재적인 위해성을 제시하고자 시도하였다. 미국실새삼의 기생은 구상나무와 신갈나무와 같은 목본성 식물종(12.1%)의 목질화가 되지 않은 소지나 잎에서도 관찰되었다. 미국실새삼의 기주식물종은 국화과에 속하는 종이 가장 많았고, 과내 차지하는 기주식물종의 비율은 사초과, 마디풀과 그리고 콩과 등의 것에서 높았다. 기생 유도 실험을 통해 미국실새삼은 1종을 제외한 모든 식물에 기생할 수 있음이 확인됨으로써 이 침입식물의 분포의 제한 요인은 분산과정이라는 것을 알 수 있었다. 기주식물의 감염된 부위는 줄기와 잎 두 곳에서 대부분 나타났고, 드물게 잎이나 줄기에만 나타나기도 하였다. 이 연구로 12개 과의 기숙식물 45종(12개 과의 초본식물 33종과 목본식물 12종)을 새롭게 추가하였다. 그 중에는 조와 같은 농작물뿐만 아니라 멸종위기야생식물 6종에도 기생하였고, 특히 후자의 경우에는 미국실새삼의 기생으로 식물체가 고사까지 당하는 경우도 있었다. 이는 미국실새삼이 잠재적으로 야생식물에게도 확산될 가능성이 높다는 것을 의미한다.

A Web-based Information System for Plant Disease Forecast Based on Weather Data at High Spatial Resolution

  • Kang, Wee-Soo;Hong, Soon-Sung;Han, Yong-Kyu;Kim, Kyu-Rang;Kim, Sung-Gi;Park, Eun-Woo
    • The Plant Pathology Journal
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    • 제26권1호
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    • pp.37-48
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    • 2010
  • This paper describes a web-based information system for plant disease forecast that was developed for crop growers in Gyeonggi-do, Korea. The system generates hourly or daily warnings at the spatial resolution of $240\;m{\times}240\;m$ based on weather data. The system consists of four components including weather data acquisition system, job process system, data storage system, and web service system. The spatial resolution of disease forecast is high enough to estimate daily or hourly infection risks of individual farms, so that farmers can use the forecast information practically in determining if and when fungicides are to be sprayed to control diseases. Currently, forecasting models for blast, sheath blight, and grain rot of rice, and scab and rust of pear are available for the system. As for the spatial interpolation of weather data, the interpolated temperature and relative humidity showed high accuracy as compared with the observed data at the same locations. However, the spatial interpolation of rainfall and leaf wetness events needs to be improved. For rice blast forecasting, 44.5% of infection warnings based on the observed weather data were correctly estimated when the disease forecast was made based on the interpolated weather data. The low accuracy in disease forecast based on the interpolated weather data was mainly due to the failure in estimating leaf wetness events.

치과의료기관 종사자의 치과의료기관 평가제도에 대한 수용에 관한 연구 - 감염관리 부문을 중심으로 - (A Study on Dental Hospital Staff's Acceptance toward the Dental Institutions Accreditation System - A Study of Infection Management Part -)

  • 송영채;김상만;엄기현;장성일
    • 한국병원경영학회지
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    • 제15권3호
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    • pp.123-142
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    • 2010
  • The Government is going to enforce assessment of dental institutions in addition to assessment of medical institutions so that it can provide good-quality medical service to people having much interest in quality of medical service. But the empirical research on the assessment of dental institutions which is still in a model assessment stage, is insufficient. Accordingly, the present research aims to help dental institutions preparing the main assessment by researching an acceptance level of workers of dental institutions in a process performing assessment of dental institutions, based on the preceding researches that the perceived utility has influence on implementation intention. The present research proved the influence that job relevance, result demonstration, usability and education & training of workers and manager's leadership of an infection management part affects perceived utility and implementation intention. As a research result, all the job relevance, result demonstration, usability have a positive(+) influence on perceived utility and implementation intention, and the influence of job relevance most affects especially. The leadership and education & training have influence on what workers get to have implementation intention after perception of utility of infection management according to the order. According to the above results, it can be understood that medical institutions preparing for assessment of dental institutions take charge of the assessment part having high relevance with work of workers and need to make a manager ordering performance of its assessment be able to foster a leadership for improving effectiveness of assessment performance.

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Roy's Adaptation Model에 의한 모성영역에서의 간호진단 확인연구 (A Study for Identification of Nursing Diagnosis using the Roy's Adaptation Model in Maternity Unit)

  • 조정호
    • 대한간호
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    • 제33권3호
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    • pp.79-91
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    • 1994
  • The purpose of this study was to identify the meaningful nursing diagnosis in maternity unit and to suggest formally the basal data to the nursing service with scientific approach. The subject for this paper were 64 patients who admitted to Chung Ang University Hospital, Located in Seoul, from Mar. 10, to July 21, 1993. The results were as follows: 1. The number of nursing diagnosis from 64 patients were 892 and average number of nursing diagnosis per patient was 13.9. 2. Applying the division of nursing diagnosis to Roy's Adaptation Model, determined nursing diagnosis from the 64 patients were 621 (69.6%) in physiological adaptation mode and (Comfort, altered r/t), (Injury, potential for r/t), (Infection, potential for r/t), (Bowel elimination, altered patterns r/t), (Breathing pattern, ineffective r/t), (Nutrition, altered r/t less than body requirement) in order, and 139 (15.6%) in role function mode, (Self care deficit r/t), (Knowledge deficit r/t), (Mobility, impaired physical r/t) in order, 122 (13.7%) in interdependence adaptation mode, (Anxiety r/t), (Family Process, altered r/t) in order, 10(1.1%) in self concept adaptation mode, (Powerlessness r/t), (Grieving, dysfunctional r/t) in order. 3. Nursing diagnosis in maternity unit by the medical diagnosis, the average hospital dates were 3.8 days in normal delivery and majority of used nursing diagnosis, (Comfort, altered r/t) 64.6%, (Self care deficit r/t) 13.6% in order, and the average hospital dates were 9.6 days in cesarean section delivery and majority of used nursing diagnosis, (Comfort, altered r/t) 51.6%, (Self care deficit r/t) 15.2%, (Infection, potential for r/t) 9.9%, (Injury, potential "for r/t) 8.1%, (Anxiety r/t) 5.0%, (Mobility, impaired physical r/t) 3.3% in order, and the average hospital dates were 15.8days in preterm labor and majority of used nursing diagnosis, (Comfort, altered r/ t), (Anxiety r/t), (Injury, potential for r/t) in order, and the average short-term hospital dates were 2.5days, long-term hospital dates were 11.5days in gynecologic diseases and majority of used nursing diagnosis, (Comfort, altered r/t). (Self care deficit r/t), (Injury, potential for r/t), (Infection, potential for r/t) in order.

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수치해석을 이용한 임시대피소 내 공기감염확산 저감장치의 성능 분석 (Numerical Analysis of Airborne Infection Control Performance of Germicidal Systems in a Temporary Shelter)

  • 박정연;성민기;이재욱
    • 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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    • 제21권1호
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    • pp.7-15
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    • 2015
  • Purpose : When natural disaster occurs, the victims are evacuated to temporary shelters such as indoor gymnasiums or large space buildings until their homes are recovered. If someone in this temporary shelter is infected with an airborne infectious disease, it becomes easier for the disease to spread to the other people in the shelter than it would be under normal conditions. Therefore, temporary shelters need to provide not only water and food but also hygienic indoor conditions. Methods : In this study, the use of mechanical systems such as ultraviolet germicidal irradiation (UVGI) systems and air cleaners were simulated using numerical analysis to find out how these systems can control airborne infection in temporary shelters. An indoor gymnasium was selected as a temporary shelter for the numerical simulation model considering Korea's post-disaster response system. Influenza A virus was assumed as an airborne infectious disease and the diffusion of the virus was made by one person in the shelter. Results : The result of this study showed that the UVGI systems disinfected the virus more effectively than the air cleaners by creating a more stable airflow after the disinfection process. The air cleaners could remove the virus but since it created an unstable airflow in the temporary shelter, the virus was condensed to a certain area to show a higher virus concentration level than the source location. Implications : In the temporary shelter, it is necessary to use UVGI systems or air cleaners for hygienic indoor conditions.

An Outer Membrane Protein Preparation as a Vaccine against Pseudomonas aeruginosa Infection

  • Park, Wan-Je;Cho, Yang-Je;Ahn, Dong-Ho;Jung, Sang-Bo;Lee, Na-Gyong;Kim, Hyun-Su;Hahm, Kyung-Soo;Kim, Yu-Sam
    • Journal of Microbiology and Biotechnology
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    • 제7권2호
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    • pp.144-150
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    • 1997
  • We developed a simple and efficient method to prepare a Pseudomonas vaccine of outer membrane (OM) proteins free from lipopolysaccharide (LPS). A three step purification process including extraction, ultrafiltration and ultracentrifugation effectively removed LPS from the OM protein fraction. Approximately 2 mg of the OM proteins was obtained from 1 g of wet cell. LPS contaminant in the vaccine preparation was less than 0.003% (w/w) of protein and protease activity was not detectable. To achieve a wide range of protection, OM proteins prepared from four attenuated P. aeruginosa strains were mixed in equal amounts and used as a vaccine, which elicited in rabbits a high titer of antibody reactive to all of the seven Fisher types. The antisera from the immunized rabbit had a strong reactivity to vaccine proteins larger than 25 kDa. In a burned mouse infection model, immunization with the vaccine significantly enhanced bacterial clearance in the Pseudomonas infected skin. The vaccination also provided mice an excellent protection against Pseudomonas infection (11, 16). Data on antigenicity, mutagenicity, acute, subacute toxicity and pharmacological tests confirmed the safety of the vaccine (1, 3, 10, 12, 17). These data demonstrate that this method can be applied to manufacture a bacterial vaccine of OM proteins with safety and prophylactic efficacy at a practical low cost.

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호흡기 감염병 예방을 위한 보건소 상시 선별진료소 활용방안 연구 - 음압 결핵 검진실을 중심으로 (A Study on a space utilization plan for screening clinic in public health center by means of the prevention of respiratory infectious disease - Focused on a negative pressured tuberculosis exam room)

  • 윤형진;한수하
    • 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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    • 제27권4호
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    • pp.51-60
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    • 2021
  • Purpose: Tuberculosis(TB) care unit in public health center should be carefully considered to be re-designed as an infection safety environment for both patient and healthcare workers. So, for the enhancement, this study analyses the facility requirements for co-using the screening clinic as a TB and other respiratory disease care unit. Methods: Not only screening clinic facility guidelines from "A Study for Standard Triage Design and Construction Document" but also the guidelines of TB care and related medical facility are reviewed; KDCA, CDC, ECDC and WHO as a TB care, and FGI and NHS for facility. The facility requirements are summarized space, approach, and mechanical requirement in order. By comparing the summary and screening clinic facility guidelines, supplementations are proposed for TB care unit setting. Results: The result of this study shows that both the space program and mechanical requirement of the screening clinic and that of TB care unit are almost identical and could be share, which include direct airflow or negative air pressure in an exam room. To increase functional and economical efficiency, however, it is necessary to consider a multi-functional negative pressured room, So care process may be re-designed based on a room type; face-to-face room or glass wall inbetween. Implications: The facility guidelines for TB care unit of a public health center should be developed to build a safe environment for infection control by reflecting its medical plan and budget.

OsF3H Gene Increases Insect Resistancy in Rice through Transcriptomic Changes and Regulation of Multiple Biosynthesis Pathways

  • Rahmatullah Jan;Saleem Asif;Kyung-Min Kim
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.287-287
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    • 2022
  • In this study, we analyze RNA-seq data from OxF3Hand WT at several points (Oh, 3 h, 12 h, and 24 h) after WBPH infection. A number of the genes were further validated by RT-qPCR. Results revealed that highest number of DEGs (4,735) between the two genotypes detected after 24 h of infection. Interestingly, many of the DEGs between the WT and OsF3H under control conditions were also found to be differentially expressed in OsF3H in response to WBPH infestation. These results indicate that significant differences in gene expression between the "OxF3H" and "WT" exist as the infection time increases. Many of these DEGs were related to oxidoreductase activity, response to stress, salicylic acid biosynthesis, metabolic process, defense response to pathogen, cellular response to toxic substance, and regulation of hormones level. Moreover, genes involved in salicylic acid (SA) and Ethylene (Et) biosynthesis were upregulated in OxF3H plants while jasmonic acid (JA), Brassinosteroid (Br), and abscisic acid (ABA) signaling pathways were found downregulated in OxF3H plant during WBPH infestation. Interestingly, many DEGs related to pathogenesis such as OsPR1, OsPR1b, NPR1, OsNPR3 and OsNPR5 were found significantly upregulated in OxF3H plants. Additionally, genes related to MAPKs pathway, and about 30 WRKY genes involved in different pathways were found upregulated in OxF3H plants after WBPH infestation. This suggests that overexpression of the OxF3H gene leads to multiple transcriptomic changes and impact plant hormones, pathogenic related and secondary metabolites related genes and enhancing the plant resistance to WBPH infestation.

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분석기법을 우회하는 악성코드를 분석하기 위한 프로세스 설계 (A Novel Process Design for Analyzing Malicious Codes That Bypass Analysis Techniques)

  • 이경률;이선영;임강빈
    • 정보화정책
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    • 제24권4호
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    • pp.68-78
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    • 2017
  • 악성코드는 나날이 복잡해지고 다양화되어 단순한 정보유출에서부터 시스템에 대한 심각한 피해를 유발하는 실정에 이르렀다. 이러한 악성코드를 탐지하기 위해 코드분석에 역공학을 이용하는 많은 연구가 진행되었지만, 악성코드 개발자도 분석방법을 우회하는 다양한 기법을 활용함으로써 코드분석을 어렵게 하였다. 특히, 악성코드의 감염여부조차 판단하기 어려운 루트킷 기법들이 진화하고 있고, 악성코드가 이 기법들을 흡수함으로써 그 문제의 심각성은 더욱 커지고 있다. 따라서 본 논문에서는 분석기법들을 우회하는 악성코드에 재빠르게 대응하기 위한 분석 프로세스를 설계하였다. 설계된 프로세스를 통하여 악성코드의 탐지를 더욱 효율적으로 할 수 있을 것으로 사료된다.

돼지 Toxoplasmosis 의 간접 적혈구응집반응과 피내반응에 관한 연구 (Studies on Passive Hemagglutination Test and Skin Test for Toxoplasmosis in Swine)

  • 서명득;장두환
    • 대한수의학회지
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    • 제12권1호
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    • pp.51-58
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    • 1972
  • Hemagglutinating antigen of Toxoplasma gondii was prepared and purified by the method of a slight modification of Tsunematsu, and the preparation of the skin test antigen (toxoplasmin) was made by means of acetone-ether treatment described by Nobute et al. With these antigens the passive hemagglutionation and skin tests were performed for the diagnosis of swine toxoplasmosis by using artificially infected pigs. The results obtained were summarized as follows: 1. The hemagglutinating antibody and the skin test antibody were demonstrated one and three weeks after infection, respectively. And these antibodies were maintained over nine weeks after infection. 2. The antigenicity of hemagglutinating antigen was stable when it was kept in frozen state, while was unstable in a liquid state. 3. Freeze-dried skin test antigen (toxoplasmin) was stable for two months or more if it was kept at $5^{\circ}C$ and room temperature, but in the liquid or reconstituted state it was unstable. 4. Freeze-dried skin test antigen could be preserved without loss of antigenicity for more than two months. 5. Passive hemagglutination test could be applied effectively at the early phase of the disease process and skin test at later phase, mainly for epidemiological survey. However, by combiniation of these methods, the more accurate results could be obtained.

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