• Title/Summary/Keyword: inductive activity

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Antioxidant and Quinone Reductase Inductive Activities of Various Organs of Pepper (고추 기관별 항산화 활성과 quinone reductase 유도활성)

  • Ku, Kang-Mo;Kang, Young-Hwa
    • Journal of Applied Biological Chemistry
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    • v.53 no.1
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    • pp.31-36
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    • 2010
  • We analyzed antioxidant and quinone reductase (QR) inductive activities of various organs of pepper for utilizing by-product of them. Peppers were separated into fruits, roots, stems, and leaves and extracted with methanol for the analysis. As a result, pepper leaves showed higher phenol content than other organs. Using the DPPH assay, there was not considerably different activity depending on pepper organs, but pepper leaves showed significantly higher antioxidant activity using the ABTS assay. In FTC and TBA assay, stems and leaves showed significantly higher lipidperoxidation inhibitory activity. In QR inductive assay, pepper tissues showed different QR inductive activity: leaves>roots>>stems>fruits. In addition, pepper leaves showed highest antiproliferation activity on hepa1c1c7 among pepper tissues in $50-200\;{\mu}g/mL$. These results indicate that pepper leaves have high potential to be a good functional food material due to high QR inductive and antioxidant activities.

Cancer Chemopreventive Activity of the Rhizome Extract of Alpinia officinarum (고양강 추출물의 암예방 활성)

  • Ku, Kang-Mo;Chang, Young-Jin;Kim, Min-Gun;Kim, Kil-Ung;Song, Kyung-Sik;Kang, Young-Hwa
    • Korean Journal of Pharmacognosy
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    • v.38 no.1
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    • pp.95-99
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    • 2007
  • In order to find novel cancer chemopreventive agents, quinone reductase (QR) inductive activity of methanol extract of herbal medicines was examined using murine hepatoma, hepa1c1c7 cells. QR has been used as an anticarcinogenic marker enzyme in cancer chemoprevention study. The methanol extract of Alpinia officinarum (Zingiberace) showed showed significantly strong quinone reductase inductive activity compared to the control group. The methanol extract of Alpinia officinarum was successively fractionated with various solvents according to polarity. Hexane, ethyl acetate, buthanol and water fractions were obtained and theirs activities were assessed. The QR inductive effect was moved to the ethyl acetate fraction and was highly increased. The CD (concentration required to double the specific activity of QR) value of ethyl acetate fraction was 8.6 ${\mu}g/mL$. Alpinia officinarum also showed strong antioxidant activity. These results suggest that Alpinia officinarum can be developed as cancer chemopreventive agent.

Antioxidant and QR Inductive Activities of Novel Functional Soybean 'Agakong3'

  • Ku, Kang-Mo;Kim, Min-Gun;Hong, Mi-Jeong;Jeong, Yeon-Shin;Kim, Jeong-Sang;Lee, In-Jung;Shin, Dong-Hyun;Hwang, Young-Hyun;Kang, Young-Hwa
    • Food Science and Biotechnology
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    • v.18 no.3
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    • pp.624-629
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    • 2009
  • In order to evaluate the bioactivity of 'Agakong3', which was newly bred, quinone reductase (QR) inductive activity and antioxidant activity were both assessed. The methanol extract of 'Agakong3' showed a significantly stronger QR inductive activity than other soybeans. The methanol extract of 'Agakong3' also showed a significantly stronger cytotoxicity on hepa1c1c7 than other soybeans. 'Agakong3' exhibited the most potent antioxidant activity in the Trolox equivalent antioxidant capacity (TEAC) assay whereas it showed significantly weak antioxidant in the DPPH assay. In total phenol and flavonoid contents, 'Agakong3' showed the highest contents regarding phenol and flavonoid compounds. Major isoflavones such as daidzein and genistein were quantitified by high performance liquid chromatography. 'Agakong3' also showed the highest total isoflavone contents. Results of correlation analysis showed that there were high correlation coefficients between the contents of isoflavone and TEAC and the contents of isoflavone and QR inductive activity, respectively. These results suggest that 'Agakong3' will be a promising and functional food material.

An Analysis on the Effect of the Shape Features of the Textile Electrode on the Non-contact Type of Sensing of Cardiac Activity Based on the Magnetic-induced Conductivity Priciple (직물 전극의 형상 특성이 자계 유도성 전도율 기반의 비접촉식 심장활동 센싱에 미치는 효과의 분석)

  • Gi, Sun Ok;Lee, Young Jae;Koo, Hye Ran;Khang, Seon Ah;Park, Hee Jung;Kim, Kyeong Seop;Lee, Joo Hyeon;Lee, Jeong Whan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.62 no.6
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    • pp.803-810
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    • 2013
  • The purpose of this research is to analyze the effect of shape of the inductive textile electrode on the non-contact heart activity sensing, based on the magnetic-induced conductivity principle. Four types of the inductive textile electrodes were determined according to the combinations of the two shape features. A fiber-metal hybrid-typed conductive thread was developed and applied to materialization of the textile electrodes by embroidery method. The heart activity was extracted through the textile electrode sewn on a T-shirt. The experiments were implemented to constantly measure the heart activity for 20 seconds, in each case of 5 healthy male subjects. The heart activity signals acquired in each type of the inductive textile electrode were analyzed, 1)by drawing a comparison of morphology with those of ECG signal (LeadII), and 2)by calculation of the normalized mean and standard deviation of magnitude of the heart activity signals. The analysis resulted that the relatively better quality of signals were acquired in the 'square' types in the matter of whole shape, while the better results were obtained in 'donut' types in the matter of center hole. Accordingly, the relatively best quality of signals was obtained in the case of 'Square-Donut' type of the inductive textile electrode.

Proliferation and Functional Activity of Human Adipose Tissue-Derived CD146 Positive Endothelial Cells According to Culture Mediums (배지 성분에 따른 인간 지방조직기원 CD146 양성 혈관내피세포의 증식 및 기능의 평가)

  • Park, Bong-Wook;Hah, Young-Sool;Kim, Jin-Hyun;Cho, Hee-Young;Jung, Myeong-Hee;Kim, Deok-Ryong;Kim, Shin-Won;Kim, Uk-Kyu;Kim, Jong-Ryoul;Byun, June-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.32 no.6
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    • pp.504-510
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    • 2010
  • Purpose: This study was to examine the proliferation and function of the adipose tissue-derived endothelial cells according to different culture medium conditions. Materials and Methods: Adipose tissue-derived CD146 positive endothelial cells were cultured in according to different culture mediums (DMEM culture medium with or without osteogenic inductive agents and EBM-2 culture medium with or without osteogenic inductive agents). The proliferation and function of the adipose tissue-derived endothelial cells was examined in different culture medium conditions. Results: Adipose tissue-derived endothelial cells formed tube-like structures on Matrigel in EBM-2 culture medium with or without osteogenic inductive agents. However, the cells did not form tube-like structures on Matrigel in DMEM medium with or without osteogenic inductive agents. After 24 hours of culture, among the culture medium using EBM-2, the proliferation of the cells were promoted in EBM-2 medium without osteogenic inductive agents than in EBM-2 medium with osteogenic inductive agents. However, 72 hours of culture, the proliferation of the cells were promoted in EBM-2 medium with osteogenic inductive agents than in EBM-2 medium without osteogenic inductive agents. Conclusion: These results suggest that the proliferation and function of the adipose tissue-derived CD146 positive endothelial cells could be maintained in EBM-2 with osteogenic inductive agents.

Application of a Textile-based Inductive Sensor for the Vital Sign Monitoring

  • Gi, Sun Ok;Lee, Young Jae;Koo, Hye Ran;Khang, Seonah;Kim, Kyung-Nam;Kang, Seung-Jin;Lee, Joo Hyeon;Lee, Jeong-Whan
    • Journal of Electrical Engineering and Technology
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    • v.10 no.1
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    • pp.364-371
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    • 2015
  • In this study, we developed a feasible structure of a textile-based inductive sensor using a machine embroidery method, and applied it to a non-contact type vital sign sensing device based on the principle of magnetic-induced conductivity. The mechanical heart activity signals acquired through the inductive sensor embroidered with conductive textile on fabric were compared with the Lead II ECG signals and with respiration signals, which were simultaneously measured in every case with five subjects. The analysis result showed that the locations of the R-peak in the ECG signal were highly associated with sharp peaks in the signals obtained through the textile-based inductive sensor (r=0.9681). Based on the results, we determined the feasibility of the developed textile-based inductive sensor as a measurement device for the heart rate and respiration characteristics.

Effects of Electric Current on Flowering in Pharbitis and Floral Stimulus activity in the Phloem Exudate of Cotyledons

  • Jueson Maeng
    • Journal of Plant Biology
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    • v.37 no.2
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    • pp.159-166
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    • 1994
  • Direct current (DC) applied to cotyledons during a 16 h inductive dark period inhibited the flowering in the short-day plant, Pharbitis nil Choisy cv. Violet. The inhibitory effect of DC was more profound when the current flowed from roots to cotyledons, showing its polarity-dependent action. The second half on the inductive dark period was more sensitive to DC stimulus. The flowering was significantly depressed only when DC stimuli were applied to the translocation path of the floral stimulus from the induced cotyledon to the apex, suggesting that the transport of floral stimulus was damaged by the DC treatment. The vegetative apex culture bioassay system showed that a significant level of the floral stimulus activity existed in the phloem exudate from the cotyledons which would fail to form their own floral buds. These results strongly support the hypothesis that DC partially impede, at least temporarily, the transmission path of the floral stimulus from florally-induced cotyledon to the apex, rather than depressing in situ synthesis of the floral stimulus.

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Real-time Intrusion-Detection Parallel System for the Prevention of Anomalous Computer Behaviours (비정상적인 컴퓨터 행위 방지를 위한 실시간 침입 탐지 병렬 시스템에 관한 연구)

  • 유은진;전문석
    • Review of KIISC
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    • v.5 no.2
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    • pp.32-48
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    • 1995
  • Our paper describes an Intrusion Detection Parallel System(IDPS) which detects an anomaly activity corresponding to the actions that interaction between near detection events. IDES uses parallel inductive approaches regarding the problem of real-time anomaly behavior detection on rule-based system. This approach uses sequential rule that describes user's behavior and characteristics dependent on time. and that audits user's activities by using rule base as data base to store user's behavior pattern. When user's activity deviates significantly from expected behavior described in rule base. anomaly behaviors are recorded. Observed behavior is flagged as a potential intrusion if it deviates significantly from the expected behavior or if it triggers a rule in the parallel inductive system.

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The Effects of Inductive Activities Using GeoGebra on the Proof Abilities and Attitudes of Mathematically Gifted Elementary Students (GeoGebra를 활용한 귀납활동이 초등수학영재의 증명능력 및 증명학습태도에 미치는 영향)

  • Kwon, Yoon Shin;Ryu, Sung Rim
    • Education of Primary School Mathematics
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    • v.16 no.2
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    • pp.123-145
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    • 2013
  • This study was expected to yield the meaningful conclusions from the experimental group who took lessons based on inductive activities using GeoGebra at the beginning of proof learning and the comparison one who took traditional expository lessons based on deductive activities. The purpose of this study is to give some helpful suggestions for teaching proof to mathematically gifted elementary students. To attain the purpose, two research questions are established as follows. 1. Is there a significant difference in proof abilities between the experimental group who took inductive lessons using GeoGebra and comparison one who took traditional expository lessons? 2. Is there a significant difference in proof attitudes between the experimental group who took inductive lessons using GeoGebra and comparison one who took traditional expository lessons? To solve the above two research questions, they were divided into two groups, an experimental group of 10 students and a comparison group of 10 students, considering the results of gift and aptitude test, and the computer literacy among 20 elementary students that took lessons at some education institute for the gifted students located in K province after being selected in the mathematics. Special lesson based on the researcher's own lesson plan was treated to the experimental group while explanation-centered class based on the usual 8th grader's textbook was put into the comparison one. Four kinds of tests were used such as previous proof ability test, previous proof attitude test, subsequent proof ability test, and subsequent proof attitude test. One questionnaire survey was used only for experimental group. In the case of attitude toward proof test, the score of questions was calculated by 5-point Likert scale, and in the case of proof ability test was calculated by proper rating standard. The analysis of materials were performed with t-test using the SPSS V.18 statistical program. The following results have been drawn. First, experimental group who took proof lessons of inductive activities using GeoGebra as precedent activity before proving had better achievement in proof ability than the comparison group who took traditional proof lessons. Second, experimental group who took proof lessons of inductive activities using GeoGebra as precedent activity before proving had better achievement in the belief and attitude toward proof than the comparison group who took traditional proof lessons. Third, the survey about 'the effect of inductive activities using GeoGebra on the proof' shows that 100% of the students said that the activities were helpful for proof learning and that 60% of the reasons were 'because GeoGebra can help verify processes visually'. That means it gives positive effects on proof learning that students research constant character and make proposition by themselves justifying assumption and conclusion by changing figures through the function of estimation and drag in investigative software GeoGebra. In conclusion, this study may provide helpful suggestions in improving geometry education, through leading students to learn positive and active proof, connecting the learning processes such as induction based on activity using GeoGebra, simple deduction from induction(i.e. creating a proposition to distinguish between assumptions and conclusions), and formal deduction(i.e. proving).