• Asian Pacific Journal of Cancer Prevention
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• v.16 no.12
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• pp.5059-5062
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• 2015

Background: ALL is an irredeemable disease due to the resistance to treatment. There are several influences which are involved in such resistance to chemotherapy, including oxidative stress as a result of the generation of reactive oxygen species (ROS) and presence of hypodiploid cells. Cluster of differentiation 26 (CD26), also known as dipeptidyl peptidase-4, is a 110 kDa, multifunctional, membrane-bound glycoprotein. Aim and objectives: The aim of this study was to evaluate the clinical significance of serum CD26 in patients with acute lymphoblastic leukaemia patients in the post remission induction phase, as well as the relationship between CD26 activity and the oxidative stress status. Materials and Methods: CD26, total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI), in addition to activity of related enzymes myeloperoxidase, glutathione-s-transferase and xanthine oxidase, were analysed in sixty children with acute lymphoblastic leukaemia in the post remission induction phase. Results: The study showed significant elevation in CD26, TOS and OSI levels in patients with acute lymphoblastic leukaemia in the post remission induction phase in comparison to healthy control samples. In contrast, myeloperoxidase, glutathione-s-transferase and xanthine oxidase activities were decreased significantly. A significant correlation between CD26 concentration and some oxidative stress parameters was evident in ALL patients. Conclusions: Serum levels of CD26 appear to be useful as a new biomarker of oxidative stress in children with acute lymphoblastic leukaemia in the post remission induction phase, and levels of antioxidants must be regularly estimated during the treatment of children with ALL.

• Journal of Korean Society for Atmospheric Environment
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• v.25 no.4
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• pp.304-315
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• 2009

Numerical simulations were carried out to understand the effect of Sea Surface Temperature (SST) spatial distribution on regional circulation. A three-dimensional non-hydrostatic atmospheric model RAMS, version 6.0, was applied to examine the impact of SST forcing on regional circulation. New Generation Sea Surface Temperature (NGSST) data were implemented to RAMS to compare the results of modeling with default SST data. Several numerical experiments have been undertaken to evaluate the effect of SST for initialization. First was the case with NGSST data (Case NG), second was the case with RAMS monthly data (Case RM) and third was the case with seasonally averaged RAMS monthly data (Case RS). Case NG showed accurate spatial distributions of SST but, the results of RM and RS were $3{\sim}4^{\circ}C$ lower than buoy observation data. By analyzing practical sea surface conditions, large difference in horizontal temperature and wind field for each run were revealed. Case RM and Case RS showed similar horizontal and vertical distributions of temperature and wind field but, Case NG estimated the intensity of sea breeze weakly and land breeze strongly. These differences were due to the difference of the temperature gradient caused by different spatial distributions of SST. Diurnal variations of temperature and wind speed for Case NG indicated great agreement with the observation data and statistics such as root mean squared error, index of agreement, regression were also better than Case RM and Case RS.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.174-174
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• 2014

Memristor devices are one of the most promising candidate approaches to next-generation memory technologies. Memristive switching phenomena usually rely on repeated electrical resistive switching between non-volatile resistance states in an active material under the application of an electrical stimulus, such as a voltage or current. Recent reports have explored the use of variety of external operating parameters, such as the modulation of an applied magnetic field, temperature, or illumination conditions to activate changes in the memristive switching behaviors. Among these possible choices of signal controlling factors of memristor, photon is particularly attractive because photonic signals are not only easier to reach directly over long distances than electrical signal, but they also efficiently manage the interactions between logic devices without any signal interference. Furthermore, due to the inherent wave characteristics of photons, the facile manipulation of the light ray enables incident light angle controlled memristive switching. So that, in the tautological sense, device orienting position with regard to a photon source determines the occurrence of memristive switching as well. To demonstrate this position controlled memory device functionality, we have fabricated a metal-semiconductor-metal memristive switching nanodevice using ZnO nanorods. Superhydrophobicity employed in this memristor gives rise to illumination direction selectivity as an extra controlling parameter which is important feature in emerging. When light irradiates from a point source in water to the surface treated device, refraction of light ray takes place at the water/air interface because of the optical density differences in two media (water/air). When incident light travels through a higher refractive index medium (water; n=1.33) to lower one (air; n=1), a total reflection occurs for incidence angles over the critical value. Thus, when we watch the submerged NW arrays at the view angles over the critical angle, a mirror-like surface is observed due to the presence of air pocket layer. From this processes, the reversible switching characteristics were verified by modulating the light incident angle between the resistor and memristor.

• Natural Product Sciences
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• v.24 no.1
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• pp.21-27
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• 2018

Psoriasis is an auto-immune skin disease, which is characterized by the excessive generation of plaques on the skin with typically a long-lasting red, itchy and scaly symptoms. Imiquimod, which has been used for the treatment of external genital warts, actinic keratosis, and superficial basal cell carcinoma, induced of psoriasis-like skin disorders with skin erythema and thickness in mice. In the present study, we tried to find the bioactive herbal extract against imiquimod-induced psoriasis-like skin disorder in mice. During the searching of the herbal extract with anti-psoriatic effect, the ethanolic extract of Cnidium officinale ameliorated imiquimod-induced psoriasis-like skin disorder in mice. The morphological evaluation, H&E staining and Psoriasis Area and Severity Index (PASI) score showed that ear and back thickness, and erythema induced by imiquimod were significantly reversed after the treatment of the cream of the ethanolic extract of C. officinale. The overexpressed myeloperoxidase (MPO) and keratin 6A levels were decreased by the treatment of C. officinale cream. Also, $IFN-{\gamma}$, c-fos and $I{\kappa}B-{\alpha}$ mRNA levels, which are related to the progression of psoriasis, were reduced by C. officinale cream. Thus, the ethanolic extract of C. officinale ameliorated psoriasis-like skin disorder induced by imiquimod and might be the therapeutic agent for psoriasis.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.590-590
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• 2012

A transparent conducting oxide (TCO) layer was applied in crystalline Si (c-Si) solar cells without use of the conventional SiNx-coating. A high quality indium-tin-oxide (ITO) layer was directly deposited on an emitter layer of a Si wafer. Three different types of emitters were formed by controlling the phosphorous diffusion condition. A light-doped emitter forming a thinner emitter junction showed an improved photoconversion efficiency of 14.1% comparing to 13.2% of a heavy-doped emitter. This was induced by lower recombination within a narrower depletion region of the light-doped emitter. In the aspect of light management, the intermediate refractive index of ITO is effective to reduce the light reflection leading the enhanced carrier generation in a Si absorber. For the electrical aspect, the ITO layer serves as an efficient electrical conductor and thus relieves the burden of high contact resistance of the light-doped emitter. Additionally, the ITO works as a buffer layer of Ag and Si and certainly prevents the shunting problem of Ag penetration into Si emitter region. It discusses an efficient design scheme of TCO-embedded emitter Si solar cells.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.6
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• pp.30-36
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• 2011

The current test methods are insufficient to evaluate and ensure the safety and reliability of vehicle system for all possible dynamic situation including the worst case such as rollover, spin-out and so on. Although the known NHTSA Sine with dwell steering maneuvers are applied for the vehicle performance assessment, they aren't enough to estimate other possible worst case scenarios. Therefore, it is crucial for us to verify the various worst cases including the existing severe steering maneuvers. This paper includes useful worst case based upon the existing worst case scenarios mentioned above and worst case evaluation for vehicle dynamic controller in simulation basis and UCC HILS. The only human steering angle is selected as a design parameter here and optimized to maximize the index function to be expressed in terms of both yaw rate and side slip angle. The obtained scenarios were enough to generate the worst case to meet NHTSA worst case definition. It has been concluded that the new procedure in this paper is adequate to create other feasible worst case scenarios for a vehicle dynamic control system.

• Proceedings of the Korean Society of Crop Science Conference
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• 1999.11a
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• pp.25-79
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• 1999

To evaluate the historical changes and future counterplan of food culture in Korea . the following were surveyed : the scale of foodseivice industry. the consumer attitude on functional health food. the fancy and using frequency of fastfood in the growing generation, the actual state on use of imported food. consumer opinions in selecting factor of functional and organic foods. the actual state and consumer attitude on the imported foods, long-term prospect of food service industry in futures. the production of food rubbishes and their reusing rates. the production scales and toxicity problems of agricultural medicines including the postharvest agricultural medicine. the consumer anxiety such as potential environmental and human health risks associated with GMOs (genetically modified organisms) and the import state of GMOs, long-term prospect of population increase in world, and aged population of over 65 years and their social index in Korea, self-supporting rate and national security of food in Korea. the prospect for demand and supply of grains in Korea and world. decrease of the farming population and the decrease problem of agricultural productivity. the problem on the introduction of direct payment system for a farmhouse, and other social problem etc. In cases of 1996, self-supporting rate of food in Korea was the lowest as $26.4{\%}$ in the world but those countries such as USA, UK France, Canada and Denmark were $134.0{\%}\;122.0{\%}$. $190.0{\%}$. $179.0{\%}\;and\;134.0{\%}$, respectively. in 1997 Therefore. our food security appeared as a very serious problem in a viewpoint of the national security That's why this very important Symposium will be held by agriculture-related three Societies to see the last year of 1999 out and the new millennium in.

• Journal of the Korea Society of Computer and Information
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• v.13 no.4
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• pp.141-150
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• 2008

In this mobile computing environment, data broadcasting is widely used to resolve the problem of limited power and bandwidth of mobile equipments. Most previous broadcast indexing methods concentrate on flat data. However. with the growing popularity of XML, an increasing amount of information is being stored and exchanged in the XML format. We propose a novel indexing method. called TOP tree(Tree Ordering based Path summary tree), for indexing XML document on mobile broadcast environments. TOP tree is a path summary tree which provides a concise structure summary at group level using global IDs and element information at local level using local IDs. Based on the TOP tree representation, we suggest a broadcast stream generation and query Processing method that efficiently handles not only simple Path queries but also multiple path queries. We have compared our indexing method with other indexing methods. Evaluation results show that our approaches can effectively improve the access time and tune-in time in a wireless broadcasting environment.

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2001.12a
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• pp.38-47
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• 2001

L-theanine is a unique amino acid, found almost solely in tea plants. It is the main component responsible for the exotic taste of green tea. In our studies of L-theanine, we have found a variety of biological activities including relaxation and the alleviation of PMS. In general, animals generate very weak electric pulses on the surface of the brain, called brain waves. Brain waves are classified into four types, namely $\alpha$, $\beta$, $\delta$ and $\theta$-waves, based on their frequency. Brain waves correlate with individual mental conditions. For example, generation of $\alpha$-waves is considered an index of relaxation. In human volunteers, $\alpha$-waves were generated on the occipital and parietal regions of the brain surface within 40 minutes after the oral administration of 50 or 200 mg Suntheanine$^{TM}$ without causing drowsiness. Premenstrual Syndrome (PMS) is a symptom unique to women which appears in the luteal phase from the ovulation period through the first day of menstruation. It possesses characteristics of having a peak just prior to menstruation and disappearing 1 - 2 days following the start of menstruation. Symptoms of PMS are generally categorized as mental, physical and social symptoms. When comparing the reported Symptoms of PMS by the methods of MDQ score, the Suntheanine$^{TM}$ group was found to have a lower incidence of PMS symptoms, including physical, mental and social symptoms. Overall, a significant alleviation of PMS symptoms by the administration of 200 mg Suntheanine$^{TM}$ was observed. With the successful industrial production of L-theanine, we are now able to supply Suntheanine$^{TM}$, offering a tremendous opportunity for designing functional foods targeting relaxation and the alleviation of PMS.

• Journal of the Korean Society for Railway
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• v.13 no.6
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• pp.595-600
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• 2010

The Bimodal Tram being developed in Korea is a new transit system that provides both benefits of rail and bus systems in terms of accessibility and fixed time schedule. The Bimodal Tram is expected to take an important role of transit system in Korea under the national strategy of transportation system such as 'Low Carbon and Green Growth' for the next generation. This study does define the key indices considered for a decision of introducing the Bimodal Tram system and develop a finalized index, BSI(Bimodal Score for Introduction), showing the level of Bimodal Tram system introduced at a city level. The transport/transit system varies depending on cities with respect to demographic characteristics, travel patterns, financial capabilities, etc. This study will help any cities where transport agencies are trying to introduce the Bimodal Tram as a new transit system.