• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3429-3436
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• 2013

Cervical cancer is a major health problem worldwide and is the most frequent cause of cancer in women in India. Early detection and affordable drugs with clinical efficacy have to go hand-in-hand in order to comprehensibly address this serious health challenge. Plant-based drugs with potent anticancer effects should add to the efforts to find a cheap drug with limited clinical side effects. Keeping this very purpose in mind, an attempt has been made in this review to explore the potential of plant extracts or constituents known to exhibit antitumorigenic activity or exert cytotoxic effect in human cervical carcinoma cells. Alkaloids such as those isolated from C. vincetoxicum and T. Tanakae, naucleaorals A and B, isolated from the roots of N. orientalis, (6aR)-normecambroline, isolated from the bark of N. dealbata appear promising in different human cervical carcinoma cells with the $IC_{50}$ of 4.0-8 ${\mu}g/mL$. However, other compounds such as rhinacanthone and neolignans isolated from different plants are not far behind and kill cervical cancer cells at a very low concentrations. Among plant extracts or its constituents that enhance the effect of known anticancer drugs, noni, derived from the plant M. citrifolia perhaps is the best candidate. The cytotoxic potency and apoptotic index of cisplatin was found to significantly enhanced in combination with noni in different human cervical carcinoma cells and it therefore holds significance as promising herbal-based anticancer agent. However, efficacy needs to be further investigated in various cervical cell lines and more importantly, in in vivo cervical cancer models for possible use as an alternative and safe anticancer drug.

• 한국연초학회지
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• 제3권2호
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• pp.123-128
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• 1981

For evaluating the cigarette smoke quality of nonblended and commercial cigarettes, four modified smoke quality indexes were deduced from considering the reactivity of the thiol group in cystine (SH value) with the cigarette smoke constituents, and from the maximum limited contents of tar. nicotine, and carbon monoxide for the less harmful cigarettes. These results were discussed with respect to correlation coefficients between the indexes and tar/nicotine ratio which had been known reliable for smoke quality evaluation. Among the three indexes, the SH/[(N/O.6) +($\frac{C+T}{8}$)] index was found to be the most reliable and applicable.

• 화약ㆍ발파
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• 제28권2호
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• pp.59-68
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• 2010

도심지에서의 건물해체 및 발파공사로 노후된 인접 구조물의 구조적 안정성에 영향을 미칠 가능성이 있다. 본 연구에서는 노후 콘크리트 재료의 물성을 파악하기 위하여 반발경도에 의한 압축강도와 X선 회절 및 상 분석에 의한 성분 함량으로 상관성을 비교하였고, 충격 에너지에 의한 손상도 평가를 위해 측정된 탄성파속도 값으로 손상도를 산출하였다. 결과적으로, 반발경도에 의한 압축강도와 재료의 성분 함량은 상관성이 있음을 확인하였고, 탄성파속도 값으로 산출된 손상도는 압축강도가 큰 재료일수록 작게 나타났고, 충격력이 작을수록 작게 나타났다.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.445-449
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• 2005

Various methods to detect the phytoplankton/red tide blooms in the oceanic waters have been developed and tested on satellite ocean color imagery since the last two and half decades, but accurate detection of blooms with these methods remains challenging in optically complex turbid waters, mainly because of the eventual interference of absorbing and scattering properties of dissolved organic and particulate inorganic matters with these methods. The present study introduces a new method called Red tide Index (Rl), providing indices which behave as a good measure of detecting red tide algal blooms in high scattering and absorbing waters of the Korean South Sea and Yellow Sea. The effectiveness of this method in identifying and locating red tides is compared with the standard Ocean Chlorophyll 4 (OC4) bio-optical algorithm applied to SeaWiFS ocean imagery, acquired during two bloom episodes on 27 March 2002 and 28 September 2003. The result revealed that OC4 bio-optical algorithm falsely identifies red tide blooms in areas abundance in colored dissolved organic and particulate inorganic matter constituents associated with coastal areas, estuaries and river mouths, whereas red tide index provides improved capability of detecting, predicting and monitoring of these blooms in both clear and turbid waters.

• Structural Engineering and Mechanics
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• 제24권4호
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• pp.447-461
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• 2006

Here, the axisymmetric free flexural vibrations and thermal stability behaviors of functionally graded spherical caps are investigated employing a three-noded axisymmetric curved shell element based on field consistency approach. The formulation is based on first-order shear deformation theory and it includes the in-plane and rotary inertia effects. The material properties are graded in the thickness direction according to the power-law distribution in terms of volume fractions of the constituents of the material. The effective material properties are evaluated using homogenization method. A detailed numerical study is carried out to bring out the effects of shell geometries, power law index of functionally graded material and base radius-to-thickness on the vibrations and buckling characteristics of spherical shells.

• Journal of Applied Biological Chemistry
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• 제51권2호
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• pp.61-65
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• 2008

Three phenolic glycosides, gastrodin (1), parishin (2), and parishin B (3) were isolated from the n-BuOH fraction of Gastrodia elata (Orchidaseae) by medium pressure liquid chromatography. Their chemical structures were identified by the interpretation of their spectral data and direct comparison with literature values. Gastrodin and parishin were isolated as the major constituents in G. elata. Gastrodin may be a suitable index component for quality control of G. elata.

• 생약학회지
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• 제28권1호
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• pp.21-25
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• 1997

The diets with three types of triterpenoid constituents, which were isolated from Lactuca indica, provoked significant changes of serum lipoprotein-cholesterol meta bolisms of hypercholesterolemic rats induced by high-cholesterol diet, together with the reduction of atherogenic index. Especially, triterpene acetates which have triterpene moieties such as ${\beta}-amyrin$, ${\alpha}-amyrin$, lupeol, pseudotaraxasterol, taraxasterol and germanicol showed a considerable hypocholesterolemic activity. The rat given orally with triterpene acetates did not exhibit a significantly higher value of atherogenic index than that of normal rats.

• 한국환경농학회지
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• 제11권3호
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• pp.261-268
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• 1992

식물 세포의 미토콘드리아와 엽록체는 광 증감제로 작용할 가능성이 있는 여러 가지 색소들을 함유하고 있다. 이들 색소들은 대부분이 막에 결합되어있으며 청색광 영역에서 강한 흡수대를 가지므로 청색광하에서 노출된 이들 소기관에서는 활성산소가 발생되어 막의 구조적, 기능적 피해를 유발하는 요인이 된다. 활성산소의 광발생에 따른 막구조의 변화는 일차적으로 막지질 지방산성분의 산화적 파괴에 기인할 것이다. 본 연구에서는 식물이 고광도의 가시광선(특히 청색광선)하에서 일어나는 막지질 지방산의 산화적 파괴에 지방산 대신 상대적으로 둔감한 포화 지방산의 조성비를 높일 것이라고 가정하고, 이를 뒷받침할만한 실험결과를 얻었다. 즉, 광질이 서로 다른 가시광선 처리조건하에서 생장중인 식물 및 그 소기관들을 대상으로 막지질의 과산화, 지방산조성 및 불포화도, 막결합 단백질의 활성 등을 측정하고 이를 제시하였다.

• Weed & Turfgrass Science
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• 제3권4호
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• pp.347-353
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• 2014

This study was conducted to investigate the effects of composted liquid manure (CLM) on soil properties and turf quality of zoysiagrass. The CLMs were produced at 5 facilities for livestock excretions treatments located in Cheongwon, Gunwi, Iksan, Nonsan, and Yeoju in Korea, respectively. Field experiments were conducted at 5 golf courses and a sod farm located near each facility for livestock excretion treatments. Chemical fertilizer (CF) with N at $12g\;m^{-2}year^{-1}$ and CLMs were applied four times, respectively. The constituents of the different CLMs were variable based on when and where the fertilizer was produced. Soil K content significantly increased when the soil was treated with CLMs. The soil treated with CF showed a higher content of total P than that treated with CLM. CF and CLMs treatments significantly increased the turf color index compared with control. Tiller density and shoot dry weight of fertilized plots were also higher than those of non-fertilized plots. However, there was no significant difference in turf color index and tiller density among plots treated by CLMs or CF. The results of this study demonstrated that CLMs could be a substitute for CF.

• Steel and Composite Structures
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• 제23권3호
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• pp.251-261
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• 2017

In this paper, thermal effect on the vibration and stability of initially stressed sandwich plates with functionally graded material (FGM) face sheets is analyzed. Material properties of FGM face sheet are graded continuously in the thickness direction. The variation of FGM properties assumes a simple power law distribution in terms of the volume fractions of the constituents. The governing equations of arbitrarily initially-stressed sandwich plates including the effects of transverse shear deformation and rotary inertia are derived. The initial stress is taken to be a combination of a uniaxial extensional stress and a pure bending stress in the examples. The eigenvalue problems are formed to study the vibration and buckling characteristics of simple supported initially stressed FGM/metal/FGM plates. The effects of volume fraction index, temperature rise, initial stress and layer thickness of metal on the natural frequencies and buckling loads are investigated. The results reveal that the volume fraction index, initial stresses and layer thickness of metal have significant influence on the vibration and stability of sandwich plates with FGM face sheets.