• Bulletin of the Korean Chemical Society
• /
• v.31 no.10
• /
• pp.3035-3037
• /
• 2010

• Analytical Science and Technology
• /
• v.26 no.6
• /
• pp.353-356
• /
• 2013

A method on the determination of caffeine in beverage with acridiene orange-${\beta}$-cyclodextrin (CD) inclusion complex was developed. The conditions such as pH of the sample solution and concentration of acridine orange and ${\beta}$-CD were optimized to 12.0(${\pm}0.5$), $1.9{\times}10^{-6}M$ and $1.25{\times}10^{-3}M$, respectively. Under these optimum conditions, the calibration curve of caffeine was obtained over concentration range of $5{\times}10^{-5}{\sim}1.1{\times}10^{-3}M$. The detection limit was $1.0{\times}10^{-5}M$. The relative errors(%) in beverage samples were less than 5.0%.

• Environmental Analysis Health and Toxicology
• /
• v.12 no.3_4
• /
• pp.75-84
• /
• 1997

Chromatographic retention behavior and separation of various phenol derivatives on a Partisil 10 ODS 3 column-with mobile phase containing $\alpha$-cyclodextrin-were systematically studied. The decrease in k' values caused by the addition of cyclodextrins in the mobile phase was based on the formation of an inclusion complex, resulting in weakening of the hydrophobic interaction between solutes and the stationary phase. The content of the organic solvent in the mobile phase also influenced k' values of the solutes, and k' values increased with a decrease of the content of organic solvent in the mobile phase. A simple equation has been derived that reveals the hyperbolic dependence of the capacity factor on the total concentration of cyclodextrin. A plot of the reciprocal of the capacity factor against (CD)$_T$ gives a straight line and the dissociation constant, K$_D$, of the inclusion complex can be calculated from the slope. The capacity factor decreased with increasing temperature. The enthalpy was calculated from the slope of van't Hoff plots. Under optimum conditions, some mixtures of phenol derivatives were able to separated successfully.

• Journal of Pharmaceutical Investigation
• /
• v.26 no.4
• /
• pp.257-261
• /
• 1996

The seeds of Zizyphus Jujuba have been used as an antianxiety agent for the treatment of insomnia from the earliest times. Sanjoinine-A, isolated from the seeds of Zizyphus Jujuba, have been found to have a minor tranquilizer activity. However this drug is poorly soluble in water. In order to increase the dissolution rate of sanjoinine-A, solid dispersions with PVP-MC and inclusion complex with ${\beta}-cyclodextrin$ were prepared and evaluated. All of these systems increased the dissolution rate of sanjoinine A comparing with sanjoinine-A free base. From pH-rate profile of sanjoinine-A at $60^{\circ}C$, it was found that sanjoinine A was relatively stable in acidic solution, but unstable in basic solution.

• The Pure and Applied Mathematics
• /
• v.20 no.4
• /
• pp.243-249
• /
• 2013

Let A be an algebra and D a derivation of A. Then D is called algebraic nil if for any $x{\in}A$ there is a positive integer n = n(x) such that $D^{n(x)}(P(x))=0$, for all $P{\in}\mathbb{C}[X]$ (by convention $D^{n(x)}({\alpha})=0$, for all ${\alpha}{\in}\mathbb{C}$). In this paper, we show that any algebraic nil derivation (possibly unbounded) on a commutative complex algebra A maps into N(A), where N(A) denotes the set of all nilpotent elements of A. As an application, we deduce that any nilpotent derivation on a commutative complex algebra A maps into N(A), Finally, we deduce two noncommutative versions of algebraic nil derivations inclusion range.

• Journal of applied mathematics & informatics
• /
• v.29 no.1_2
• /
• pp.49-53
• /
• 2011

In this paper, we adopt a numerical method to establish the smallest set to contain all Ger$\v{s}$gorin discs of a given complex matrix and its some similar matrices. With the smallest set, a new estimation for all eigenvalues of the matrix is obtained.

• Journal of Pharmaceutical Investigation
• /
• v.16 no.2
• /
• pp.55-67
• /
• 1986

Inclusion complexation of tiaprofenic acid (TPA) with cyclodextrins $({\alpha}-,\;{\beta}-,\;{\gamma}-CyDs)$ in aqueous solution and in solid phase was investigated by solubility method, measurement of partition coefficient, ultra-violet, circular dichroism, infrared spectroscopies, powder X-ray diffractometry and differential scanning calorimetry. Investigations were made to prepare inclusion complexes of TPA with ${\beta}-CyD$ in solid powdered form by coprecipitation, freeze-drying, spray-drying and co-pulverization methods. The coprecipitation, freeze-drying and spray-drying methods were successful in obtaining inclusion complexes. The results showed that the latter two methods might be originally superior to the former in obtaining powdered inclusion completes. Especially, it was shown by powder X-ray diffractometry that spray-dried ${\beta}-CyD$ alone, TPA-spray-dried ${\beta}-CyD$ physical mixture, and spray-dried $TPA-{\beta}-CyD$ complex were amorphous. The dissolution behaviours of $TPA-{\beta}-CyD$ systems prepared by above four methods were compared with those of TPA alone and $TPA-{\beta}-CyD$ physical mixture, and the rates of dissolution of TPA in pH 1.2 buffer were greatly enhanced by inclusion complexation and copulverization.

• Proceedings of the Korean Society of Life Science Conference
• /
• 2002.03a
• /
• pp.68-68
• /
• 2002

• Bulletin of the Korean Chemical Society
• /
• v.22 no.12
• /
• pp.1397-1399
• /
• 2001

• Journal of the Korean Chemical Society
• /
• v.53 no.4
• /
• pp.399-406
• /
• 2009

The fluorescence study was performed to see whether the adsorption orientation of 4-biphenyl acetonitrile(BPAN) on metal colloids can be changed by forming an inclusion complex with $\alpha$-cyclodextrin($\alpha$-CD). The fluorescence quenching was observed with increasing temperature to confirm the direct adsorption of BPAN to the Au and Ag colloidal surfaces. BPAN adsorbed on the metal colloids formed inclusion complex with $\alpha$-CD regardless of the kinds of metal colloids. The formation constants, 32 $M^{-1}$ and 13 $M^{-1}$ for Au and Ag colloids respectively, were obtained with Benesi-Hildebrand plot. The molecules adsorbed on both the Au and Ag colloidal surfaces behaved similarly to each other, leading to the conclusion that the orientation of BPAN adsorbed on the metal colloids can be modified with $\alpha$-CD.