• 한국구조물진단유지관리공학회 논문집
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• 제17권4호
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• pp.48-56
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• 2013

프리텐션 방식을 사용한 PSC 휨부재는 시공이 간편하고 품질관리가 용이하기 때문에 최근 토목분야에서 적용된 사례가 증가하고 있다. 특히, PSC 휨부재의 종류 중 하나인 반단면 프리캐스트 콘크리트 합성 슬래브는 롱라인 공법을 적용하여 최근에 개발되었다. 반단면 프리캐스트 콘크리트 합성 슬래브는 프리캐스트 콘크리트와 현장타설 콘크리트를 합성하여 제작한다. 이 연구에서는 롱라인 공법으로 제작한 프리캐스트 PSC를 적용한 반단면 프리캐스트 콘크리트 합성 슬래브의 프리스트레스 도입 효율과 휨강도에 대한 실험을 실시하고 그 결과를 제시하였다. 롱라인 공법은 한번의 긴장력 도입으로 여러 개의 부재를 생산할 수 있는 장점이 있다. 또한, 프리캐스트 PSC 내에 매입되어 있는 철근의 영향을 고려하여 반단면 프리캐스트 콘크리트 합성 슬래브의 휨강도를 합리적으로 평가할 수 있는 식을 제시하였다.

• BLOOD RESEARCH
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• 제53권4호
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• pp.320-324
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• 2018

Background Recent studies have devoted much attention to non-protein-coding transcripts in relation to a wide range of malignancies. MALAT1, a long non-coding RNA, has been reported to be associated with cancer progression and prognosis. Thus, we here determined MALAT1 gene expression in chronic lymphocytic leukemia (CLL), a genetically heterogeneous disease, and explored its possible relationships with cytogenetic abnormalities. Methods MALAT1 expression level was evaluated using real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) on blood mononuclear cells from 30 non-treated CLL patients and 30 matched healthy controls. Cytogenetic abnormalities were determined in patients by fluorescence in situ hybridization (FISH). Results MALAT1 expression level was up-regulated in the CLL group compared to healthy controls (P=0.008). Del13q14, followed by Del11q22, were the most prevalent cytogenetic abnormalities. We found no association between the FISH results and MALAT1 expression in patients. Conclusion Altered expression of MALAT1 is associated with CLL development. Further investigations are required to assess the relationship between this long non-coding RNA and CLL patient survival and prognosis.

• Journal of Microbiology and Biotechnology
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• 제19권12호
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• pp.1672-1678
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• 2009

We studied the effects of aged total petroleum hydrocarbons (aged TPH) on the survival of allochthonous diesel-degrading Rhodococcus sp. strain YS-7 in both laboratory and field investigations. The aged TPH extracted from a crude-oil-contaminated site were fractionized by thin-layer chromatography/flame ionization detection (TLC/FID). The three fractions identified were saturated aliphatic (SA), aromatic hydrocarbon (AH), and asphaltene-resin (AR). The ratio and composition of the separated fractions in the aged TPH were quite different from the crude-oil fractions. In the aged TPH, the SA and AH fractions were reduced and the AR fraction was dramatically increased compared with crude oil. The SA and AH fractions (2 mg/l each) of the aged TPH inhibited the growth of strain YS-7. Unexpectedly, the AR fraction had no effect on the survival of strain YS-7. However, crude oil (1,000 mg/l) did not inhibit the growth of strain YS-7. When strain YS-7 was inoculated into an aged crude-oil-contaminated field and its presence was monitored by fluorescent in situ hybridization (FISH), we discovered that it had disappeared on 36 days after the inoculation. For the first time, this study has demonstrated that the SA and AH fractions in aged TPH are more toxic to an allochthonous diesel-degrading strain than the AR fraction.

• Clinical and Experimental Reproductive Medicine
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• 제44권4호
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• pp.201-206
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• 2017

Objective: The aim of this study was to compare the efficacy of swim-up and density gradient centrifugation (DGC) for reducing the amount of sperm with fragmented DNA, sex chromosome aneuploidy, and abnormal chromatin structure. Methods: Semen samples were obtained from 18 healthy male partners who attended infertility clinics for infertility investigations and were processed with swim-up and DGC. The percentages of sperm cells with fragmented DNA measured by the sperm chromatin dispersion test, normal sex chromosomes assessed by fluorescence in situ hybridization, and abnormal chromatin structure identified by toluidine blue staining were examined. Results: The percentage of sperm cells with fragmented DNA was significantly lower in the swim-up fraction (9.7%, p= 0.001) than in the unprocessed fraction (27.0%), but not in the DGC fraction (27.8%, p= 0.098). The percentage of sperm cells with normal X or Y chromosomes was comparable in the three fractions. The percentage of sperm cells with abnormal chromatin structure significantly decreased after DGC (from 15.7% to 10.3%, p= 0.002). The swim-up method also tended to reduce the percentage of sperm cells with abnormal chromatin structure, but the difference was not significant (from 15.7% to 11.6%, p= 0.316). Conclusion: The swim-up method is superior for enriching genetically competent sperm.

• Geomechanics and Engineering
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• 제16권2호
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• pp.125-140
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• 2018

Tianjin, which is located on the west shore of the Bohai Sea, is part of China's Circum-Bohai-Sea Region, where very weak clay is deposited. From the 1970s to the early $21^{st}$ century, Tianjin marine clay deposits have been the subject of numerous geotechnical investigations. Because of these deposits' geological complexity, great depositional thickness, high water content, large void ratio, excessive settlement, and low shear strength, the geotechnical properties of Tianjin marine clay need to be summarized and evaluated based on various in situ and laboratory tests so that Tianjin can safely and economically sustain more infrastructure in the coming decades. In this study, the properties of Tianjin marine clay, especially its consolidation properties, are summarized, evaluated and discussed. The focus is on establishing correlations between the geotechnical property indexes and mechanical parameters of Tianjin marine clay. These correlations include the correlations between the water content and the void ratio, the depth and the undrained shear strength, the liquid limit and the compression index, the tip resistance and the constrained modulus, the plasticity index and the ratio of undrained shear strength and the preconsolidation pressure. In addition, the primary consolidation properties of Tianjin marine clay, such as the intrinsic compression line (ICL), sedimentation compression line (SCL), compression index, $C_c$, coefficient of consolidation, $C_v$, and hydraulic conductivity change index, $C_{kv}$, are evaluated and discussed. A secondary consolidation property, i.e., the secondary compression index, $C_a$, is also investigated, and the results show that the ratio of $C_a/C_c$ for Tianjin marine clay can be used to calculate $C_a$ in secondary consolidation settlement predictions.

• 디자인융복합연구
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• 제16권5호
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• pp.125-140
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• 2017

본 연구는 머신러닝의 기법이 도시 형태를 분석 및 추론하는 복잡한 과정에 적용 되었을 때, 도시 공간의 변화를 감지하고 분석하며 예측 할 수 있는 가능성을 사례 연구의 근거를 통해 제시하고자 한다. 사례 연구는 미국 보스톤의 메인 스트리트를 대상으로 도시 형태를 분석하는 과정에 머신러닝의 기법을 적용 실험하여 그 효용성을 예증했던 2006년의 선행 연구의 결과를 2016년 도시 형태와 현상을 비교 재해석하여, 10년간의 변화를 도시적 관점, 정보 환경의 관점, 기술적 관점에서 분석하고 이에 유효한 도시 모니터링의 시사점을 도출했다. 먼저, 다중 참여형 정보 수집의 플랫폼이 열리면서 대용량 데이터를 실시간으로 수집할 수 있는 기술적으로 가능해 졌다. 로봇이나 드론 등 인공지능이 탑재된 기계들을 사용하여 도시 정보를 취득하고 개입할 수 있는 가능성과 신산업의 요구에 맞추어 도시 정보 체계를 바꿀 수 있는 가능성이 열려있다. 결론적으로, 현 도시의 당면 문제에 집중하고 각 지역의 특성에 맞는 모니터링 전략을 세우는 것이 중요하며, 국내에서는 최근 도시 재생의 관점이 강조되고 있으므로 그 실천적인 연구가 필요하다.

• Geomechanics and Engineering
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• 제5권4호
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• pp.363-377
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• 2013

Any structure constructed on the earth is supported by the underlying soil. Foundation is an interfacing element between superstructure and the underlying soil that transmits the loads supported by the foundation including its self weight. Foundation design requires evaluation of safe bearing capacity along with both immediate and long term settlements. Weak and compressible soils are subjected to problems related to bearing capacity and settlement. The conventional method of design of footing requires sufficient safety against failure and the settlement must be kept within the allowable limit. These requirements are dependent on the bearing capacity of soil. Thus, the estimation of load carrying capacity of footing is the most important step in the design of foundation. A number of theoretical approaches, in-situ tests and laboratory model tests are available to find out the bearing capacity of footings. The reliability of any theory can be demonstrated by comparing it with the experimental results. Results from laboratory model tests on square footings resting on sand are presented in this paper. The variation of bearing capacity of sand below a model plate footing of square shape with variation in size, depth and the effect of permissible settlement are evaluated. A steel tank of size $900mm{\times}1200mm{\times}1000mm$ is used for conducting model tests. Bearing capacity factor $N_{\gamma}$ is evaluated and is compared with Terzaghi, Meyerhof, Hansen and Vesic's $N_{\gamma}$ values. From the experimental investigations it is found that, as the depth of sand cushion below the footing ($D_{sc}$) increases, ultimate bearing capacity and settlement values show an increasing trend up to a certain depth of sand cushion.

• Geomechanics and Engineering
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• 제16권6호
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• pp.643-654
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• 2018

Tunnel excavation leads to a disturbance on the initial stress balance of surrounding soils, which causes convergences around the tunnel and settlements at the ground surface. Considering the effective impact of settlements on the structures at the surface, it is necessary to estimate them, especially in urban areas. In the present study, ground settlements due to the excavation of East-West Line 7 of the Tehran Metro (EWL7) and the Abuzar tunnels are evaluated and the effect of the lateral earth pressure coefficient ($K_0$) on their extension is investigated. The excavation of the tunnels was performed by TBMs (Tunnel Boring Machines). The coefficient of lateral earth pressure ($K_0$) is one of the most important geotechnical parameters for tunnel design and is greatly influenced by the geological characteristics of the surrounding soil mass along the tunnel route. The real (in-situ) settlements of the ground surface were measured experimentally using leveling methods along the studied tunnels and the results were compared with evaluated settlements obtained from both semi-empirical and numerical methods (using the finite difference software FLAC3D). The comparisons permitted to show that the adopted numerical models can effectively be used to predict settlements induced by a tunnel excavation. Then a numerical parametric study was conducted to show the influence of the $K_0$ values on the ground settlements. Numerical investigations also showed that the shapes of settlement trough of the studied tunnels, in a transverse section, are not similar because of their different diameters and depths of the tunnels.

• Journal of Electrochemical Science and Technology
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• 제13권1호
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• pp.54-62
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• 2022

The preparation of low-cost, simple, and scalable electrodes is crucial for the commercialization of water electrolyzers for H₂ production. Herein, we demonstrate the fabrication of cathodes through Mo-modified Zn phosphating of Ni foam (NiF) for water electrolysis, which has been largely utilized in surface coating industry. In situ growth of electrocatalytically active layers in the hydrogen evolution reaction (HER) was occurred after 1 min of phosphating to form ZnNiMoP_i, and subsequent thermal treatment and electrochemical activation resulted in the formation of ZnNiMoPO_xH_y. ZnNiMoPO_xH_y exhibited superior HER performance than NiF, primarily because of the increased electrochemically active surface area of ZnNiMoPO_xH_y compared to that of bare NiF. Although further investigations to improve the intrinsic electrochemical activity toward the HER and detailed mechanistic studies are required, these results suggest that phosphating is a promising coating method and will possibly advance the fabrication procedure of electrodes for water electrolyzers with better practical applications.

• 한국지반공학회논문집
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• 제39권6호
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• pp.13-19
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• 2023

달 얼음은 향후 인류의 심우주 탐사와 장기 체류를 위한 자원으로 활용될 수 있다. 달 얼음에 대한 기원 및 존재 유형은 여전히 가설로 남아 있다. 최근 세계 우주국에서는 달 얼음에 대한 원격탐사에서 지상탐사를 통해 정량적 매장량과 존재 유형을 밝히고자 경쟁적으로 미션을 계획하여 추진 중에 있다. 달 얼음의 매장량이 충분하다면 향후 얼음을 자원으로 활용하는 현지자원활용 개념이 각광받을 것으로 예상된다. 그러나 현재까지 얼음 추출에 따른 지반 공학적 관점에서 유의해야 하는 침하에 대한 검토는 전무한 실정이다. 본 연구에서는 인공월면토-얼음 존재 유형별로 얼음 추출로 인해 발생 가능한 침하량에 대한 실험적 연구결과를 제시하고 있다. 그 결과 초기 함수비 약 10%의 인공월면토-얼음 혼합토에서 상당한 침하가 발생하였다.