• Title/Summary/Keyword: improvement of day

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Evaluation of effect over time after oral administration of telmisartan for chronic kidney disease in cats

  • Han, Donghyun;Lee, Dong-Guk;Jung, Dong-In
    • Journal of Biomedical and Translational Research
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    • v.19 no.4
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    • pp.86-91
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    • 2018
  • Angiotensin receptor blockers, such as telmisartan, are considered effective in the treatment of hypertension and proteinuria due to chronic kidney disease (CKD) in cats. It selectively blocks the $AT_1$ receptor and does not affect the $AT_2$ receptor, thus effectively blocking the activity of the renin angiotensin aldosterone system. This study aims to compare over time the changes in various indicators, including systemic hypertension and proteinuria, before and after the administration of telmisartan in cats with CKD. Decrease in blood pressure (BP) (p<0.001) and urine protein to creatinine (UP/C) ratio (p<0.001) were found to be statistically significant over time after the administration of telmisartan. BP and the UP/C ratio were $160{\pm} 22.2$ and $0.50{\pm}0.647$ before telmisartan administration (Day 0), $150{\pm}21.0$ and $0.27{\pm}0.487$ on the 30th day (Day 30), $150{\pm}17.0$ and $0.25{\pm}0.376$ on the 60th day (Day 60), and $140{\pm}17.8$ and $0.15{\pm}0.233$ on the 90th day (Day 90) after administration, respectively. BP and UP/C were statistically significantly lower in cats with CKD over time at each time point from Day 0 to Day 90 at 30 day intervals. Especially after 90 days of telmisartan administration, the improvement of BP and UP/C were estimated to be about 20 mmHg and 0.35, respectively. In conclusion, the oral administration of telmisartan to cats with CKD is effective in improving BP and proteinuria, which has a positive effect on long-term survival in cats with CKD.

A Randomized Controlled Clinical Trial of Topical Herbal Gel Treatment for Chronic Shoulder Pain (만성 어깨 통증의 한약 추출 외용 젤 치료에 대한 임상연구)

  • Jo, Su Jeong;Choi, Young Doo;Jang, Jin Taek;Kim, Kap Sung;Lee, Seung Deok
    • Journal of Acupuncture Research
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    • v.31 no.4
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    • pp.1-9
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    • 2014
  • Objectives : The aim of this study is to evaluate the efficacy of a topical herbal gel application for the treatment of chronic shoulder pain. Methods : We compared the effects of Dapureo gel, which contains several herbal medicines known to improve shoulder pain, with those of placebo gel by double-blind method. 30 participants were randomized - 15 were assigned to treatment group and the other 15 were assigned to control group. Either Dapureo gel(treatment group) or placebo gel(control group) was applied topically by themselves, once a day for 2 weeks. Primary outcome was daily visual analogue scale(VAS) changes for shoulder pain which was self-reported for 2 weeks. Secondary outcome was the difference in the total shoulder pain and disability index(SPADI) which was measured at a baseline and 2 weeks after the treatment. Results : Primary outcome: Subjects of treatment group showed statistically significant improvement in VAS compared to control subjects continuously from the second day(p <0.05) to the fifteenth day(p <0.001). The treatment group showed 31% of pain reduction on the fifteenth day, while the control group showed only 7%. Secondary outcome: In terms of SPADI changes, the treatment group showed improvement compared to the control group(p <0.01). Conclusions : These results suggest that the topical herbal gel treatment used in this study is effective in improving chronic shoulder pain.

The Ecological Modeling for Estimation of Carrying Capacity in Masan Bay in 2002 summer (2002년 하계 마산만의 수질개선을 위한 환경용량산정 모델링)

  • Hong, Sok Jin;Lee, Won Chan;Park, Sung Eun;Jung, Rea Hong;Cho, Yoon Sik;Park, Jong Su;Kim, Dong Myung
    • Journal of Wetlands Research
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    • v.9 no.2
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    • pp.57-69
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    • 2007
  • This study focused on coastal water quality response to land-based and sediment pollution loads and estimation of the carrying capacity in Masan Bay using an ecological model with the data in summer of 2002. A residual current was simulated to have a slightly complicated pattern with ranging from 0.1 to 1.5 cm/s. In Masan Bay, pollutant materials cannot flow from the inner to the outer bay easily because of residual currents flow southward at surface and northward at the bottom. The simulation results of COD distribution showed high concentrations over 3 mg/L in the inner part of Masan Bay related pollutant discharge. For improvement seawater quality grade I in Masan Bay, it is necessary to reduce the organic and inorganic loads from point sources by more than 80%. For improvement seawater quality grade II, it is necessary to reduce the organic and inorganic loads from point sources by more than 50% and ameliorate severe polluted sediment. The carrying capacity for COD is 2.32 ton/day and 7.16 ton/day for each grade.

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Serial Electrophysiological Studies in Miller Fisher Syndrome (Miller Fisher 증후군1예에서 일련의 신경생리학적 소견)

  • Jun, Dong Chul;Park, Chun-Kang;Lee, Kyu-Yong;Lee, Young Joo;Kim, Juhan
    • Annals of Clinical Neurophysiology
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    • v.3 no.2
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    • pp.156-159
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    • 2001
  • Miller Fisher syndrome(MFS) has been the focus of conflicting opinions regarding the peripheral versus the central nature of the site of major neural injury. We present our electrophysiological findings in one case of MFS to help clarify the pattern of peripheral nerve injury in this syndrome. A 45-year-old man visited our hospital due to sudden diplopia. Initial examination revealed internuclear opthalmoplegia. The next day, his symptoms rapidly aggravated to complete external ophthalmoplegia, ataxia, and areflexia with hand and foot numbness. Serial electrophysiological studies were performed. The results of brainstem evoked potential(BAEP) and blink reflex were normal in the serial studies. Motor and sensory nerve conduction study(NCS) were normal findings in second hospital day, but ulnar sensory nerve shows no sensory nerve action potential(SNAP) and sural sensory conduction velocity was delayed in 7th hospital day. Our patient's clinical presentation began to improve on 15th hospital day, and his electrophysiologic study showed improvement on 29th hospital day. We believe that all the manifestations of MFS can be explained by the involvement of peripheral nerves without brainstem or cerebellar lesion with the serial electrophysiological studies.

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The Effect of Health Risk Factors on the Remaining Teeth of the Elderly in Day Care Center (주간보호시설노인의 건강위험요인이 잔존치아에 미치는 영향)

  • Shim, Youn-Soo;An, So-Youn;Park, So-Young
    • The Korean Journal of Health Service Management
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    • v.11 no.2
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    • pp.81-91
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    • 2017
  • Objectives : The purpose of this study was to provide basic data for the development of general and oral health improvement programs for the elderly by analyzing the effect of health risk factors on the remaining teeth of the elderly in day care centers. Methods : The subjects were 294 elderly people who used day care centers in Seoul. Results : In terms of health risk factors, the elderly who did not have diabetes or smoke had more remaining teeth. In terms of oral health risk factors, the elderly with no dental caries, periodontal disease and dental pain had more remaining teeth. Conclusions : It is necessary to activate systematic welfare services for the elderly that fit their lifestyle in the light of the health and oral health risk factors of the elderly who use day care centers.

Effects of a Video CD Rehabilitation Program for Total Knee Replacement on Range of Knee Angle and Activities of Daily Living Function (동영상 CD를 이용한 슬관절 전치환술 환자의 재활교육 프로그램이 관절가동범위 및 일상활동 수행에 미치는 효과)

  • Nam, Mun-Hee;Lee, Jung-Eun
    • Quality Improvement in Health Care
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    • v.16 no.1
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    • pp.79-89
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    • 2010
  • Background : This study was identified the effects of a video CD Rehabilitation program on the range of knee angle and activities of daily living in patients with a total knee replacement Method : The data was collected from March 1 to May 31 2009 for the control group and from July 1 to September 31 2009 for the experimental group. The control and experimental groups contained 19 subjects each. A video CD Rehabilitation program configured to 8 minutes in length was shown 8 times every other day. Result : 1. On the day of Hemovac removal, the knee angle and CPM angle in the experimental group increased significantly, but they remained relatively constant on post operation day 21. 2. The activities of daily living were significantly different in the experimental group. Conclusion : 1. On the day of Hemovac removal, the knee angle and CPM angle in the experimental group increased significantly, but they remained relatively constant on post operation day 21. 2. The activities of daily living were significantly different in the experimental group.

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Investigation of Current Status of Saturday Program Operation in Busan Metropolitan City (부산광역시의 토요 프로그램 운영실태의 탐색)

  • Park, In-Kyu;Cha, Cheol-Pyo;Park, Chang-Un
    • Journal of Fisheries and Marine Sciences Education
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    • v.24 no.5
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    • pp.739-753
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    • 2012
  • Based on 'Backpack-free day' and 'Unsupervised studying day' in the early 1980s, 10% of all schools in 2004 had at least 1 day of five-day classes a month as at least 2 days were enforced in 2006, and most elementary and middle schools had widely enforced the five-day class since 2012 March. The five-day class system expands the stage of studying from school to families and local societies to build an educational community related to school-family-local societies to provide various activities such as culture, art, sports, social, nature experiences on holidays to have the goal to foster creative future talents with proper personality understanding and considering others. In Busan, the five-day week class of Saturday program is being operated in various methods by national local government and public organizations. The Saturday program of local societies registered in the Saturday school of the information sharing networks are 2823 in total for the past 6 years which are being operated by national local government and public organizations. However, participation of students in the Saturday program is around 20% in 2012 March when Saturday holiday system was widely conducted. For this, problems in the Saturday programs that are currently being enforced are to be closely analyzed and participation expansion plans are to be made. Therefore, this study analyzes and investigates operation forms of Saturday programs conducted in Busan to propose an improvement plan to fulfill goals of Saturday programs and boost participation of students.

Improvement of Chronic Bleeding in the Patient with Unresectable Advanced Gastric Cancer Using the Decoction of Notoginseng Radix - a Case Report

  • Jeon, Hyeonjin;Park, Sora;Lee, Sookyung
    • The Journal of Korean Medicine
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    • v.37 no.2
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    • pp.104-109
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    • 2016
  • Objectives: A 74-year-old male patient with unresectable advanced gastric cancer (clinical initial stage T3N+, Borrmann type III) admitted due to gastric bleeding at tumor site. On first admission day, hemoglobin level was 5.7g/dl and performance status was grade 3 according to Eastern Cooperative Oncology Group Performance Status(ECOG-PS). After performing red blood cell transfusion as an emergency treatment, hemoglobin level was increased up to 9.5g/dl. However, bleeding of oozing site was continued. For hemostasis, decoction of notoginseng radix (30g/day) was administered since day 7 after admission. The dose was elevated to 40g/day after hemoglobin level was decreased to 6.5g/dl on day 11. Since then, melena was stopped and hemoglobin level was maintained over 9.1g/dl. This case shows the hemostasis effect of decoction of notoginseng radix on gastric bleeding in unresectable advanced gastric cancer.

Development of Peak Power Demand Forecasting Model for Special-Day using ELM (ELM을 이용한 특수일 최대 전력수요 예측 모델 개발)

  • Ji, Pyeong-Shik;Lim, Jae-Yoon
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.64 no.2
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    • pp.74-78
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    • 2015
  • With the improvement of living standards and economic development, electricity consumption continues to grow. The electricity is a special energy which is hard to store, so its supply must be consistent with the demand. The objective of electricity demand forecasting is to make best use of electricity energy and provide balance between supply and demand. Hence, it is very important work to forecast electricity demand with higher precision. So, various forecasting methods have been developed. They can be divided into five broad categories such as time series models, regression based model, artificial intelligence techniques and fuzzy logic method without considering special-day effects. Electricity demand patterns on holidays can be often idiosyncratic and cause significant forecasting errors. Such effects are known as special-day effects and are recognized as an important issue in determining electricity demand data. In this research, we developed the power demand forecasting method using ELM(Extreme Learning Machine) for special day, particularly, lunar new year and Chuseok holiday.

Clinical Study of HPS-A on Various Digestive Symptoms (각종 소화기 증상에 대한 HPS-A의 임상실험)

  • Cho Chong-Kwan
    • Journal of Oriental Neuropsychiatry
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    • v.3 no.1
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    • pp.107-116
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    • 1992
  • In order to study the effect and safety of HPS-A on various digestive symptom, it was taken 3 times a day for 2 weeks on 31 patients. The results were as follows ; 1. The sex distribution was male 42% and female 58% 2. The age distribution was thirties 35% twenties 20%, forties 19% 3. The average improvement rate after 1 week was 85.2% and improvement rate of each symptom was epigastric soreness 89.9%, dyspepsia 85.1%, hunger pain 84.6% 4. The average improvement rate after 2 weeks was 94.5% and improvement rate of each symptom was epigastric soreness 96.6%,hunger pain 96.5%, dyspepsia 96.3% 5. No cases were showen side effects. Aecording to the above results, it is proved that PHS-A can be applied to care gastritis and early peptic ulcer.

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